@prefix : <https://w3id.org/brainteaser/ontology/schema/> .
@prefix dc: <http://purl.org/dc/elements/1.1/> .
@prefix ATC: <http://purl.bioontology.org/ontology/ATC/> .
@prefix OAE: <http://purl.obolibrary.org/obo/OAE_> .
@prefix bto: <https://w3id.org/brainteaser/ontology/schema/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xml: <http://www.w3.org/XML/1998/namespace> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ESCO: <http://data.europa.eu/esco/isco/> .
@prefix NCIT: <http://purl.obolibrary.org/obo/NCIT_> .
@prefix UMLS: <https://uts.nlm.nih.gov/uts/umls/concept/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix time: <http://www.w3.org/2006/time#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix SNOMEDCT: <http://purl.bioontology.org/ontology/SNOMEDCT/> .
@base <https://w3id.org/brainteaser/ontology/schema/> .

<https://w3id.org/brainteaser/ontology/schema/> rdf:type owl:Ontology ;
                                                 owl:versionIRI <https://w3id.org/brainteaser/ontology/3.0/schema/> ;
                                                 owl:imports <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl> ,
                                                             <http://www.w3.org/TR/skos-reference/skos-owl1-dl.rdf> ;
                                                 dc:title "The Brainteaser Ontology"@en ;
                                                 dcterms:contributor <https://brainteaser.health/partners/> ;
                                                 dcterms:creator <https://orcid.org/0000-0001-9219-6239> ,
                                                                 <https://orcid.org/0000-0001-9709-6392> ,
                                                                 <https://orcid.org/0000-0002-0676-682X> ,
                                                                 <https://orcid.org/0000-0002-5070-2049> ,
                                                                 <https://orcid.org/0000-0003-0362-5893> ,
                                                                 <https://orcid.org/0000-0003-4970-4554> ;
                                                 dcterms:description """The BRAINTEASER Ontology (BO) jointly models both Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS).

BO serves multiple purposes:

• to provide a unified and comprehensive conceptual view about ALS and MS, which are typically dealt with separately, allowing us to coherently integrate the data coming from the different medical partners in the project;
• to seamlessly represent both retrospective data and prospective data, produced during the lifetime of BRAINTEASER;
• to allow for sharing and re-using the BRAINTEASER datasets according to Open Science and FAIR principles."""@en ;
                                                 dcterms:license <https://creativecommons.org/licenses/by-sa/4.0/> ;
                                                 dcterms:publisher <https://brainteaser.health/> ;
                                                 rdfs:comment "The BRAINTEASER Ontology (BO) jointly models both Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS)."@en .

#################################################################
#    Annotation properties
#################################################################

###  http://purl.org/dc/elements/1.1/title
dc:title rdf:type owl:AnnotationProperty .


###  http://purl.org/dc/terms/conformsTo
dcterms:conformsTo rdf:type owl:AnnotationProperty .


###  http://purl.org/dc/terms/contributor
dcterms:contributor rdf:type owl:AnnotationProperty .


###  http://purl.org/dc/terms/license
dcterms:license rdf:type owl:AnnotationProperty .


###  http://purl.org/dc/terms/publisher
dcterms:publisher rdf:type owl:AnnotationProperty .


###  http://www.w3.org/2004/02/skos/core#broaderTransitive
skos:broaderTransitive rdf:type owl:AnnotationProperty .


###  http://www.w3.org/2004/02/skos/core#note
skos:note rdf:type owl:AnnotationProperty .


###  http://xmlns.com/foaf/0.1/name
foaf:name rdf:type owl:AnnotationProperty .


#################################################################
#    Datatypes
#################################################################

###  http://www.w3.org/1999/02/22-rdf-syntax-ns#langString
rdf:langString rdf:type rdfs:Datatype .


###  http://www.w3.org/2001/XMLSchema#date
xsd:date rdf:type rdfs:Datatype .


###  http://www.w3.org/2001/XMLSchema#gYear
xsd:gYear rdf:type rdfs:Datatype .


###  http://www.w3.org/2001/XMLSchema#time
xsd:time rdf:type rdfs:Datatype .


#################################################################
#    Object Properties
#################################################################

###  http://purl.oclc.org/NET/ssnx/ssn#isProducedBy
<http://purl.oclc.org/NET/ssnx/ssn#isProducedBy> rdfs:domain [ rdf:type owl:Class ;
                                                               owl:unionOf ( <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration>
                                                                             bto:WeatherData
                                                                           )
                                                             ] ;
                                                 rdfs:range <http://purl.oclc.org/NET/ssnx/ssn#SensingDevice> .


###  http://www.wurvoc.org/vocabularies/om-1.8/unit_of_measure
<http://www.wurvoc.org/vocabularies/om-1.8/unit_of_measure> rdfs:domain [ rdf:type owl:Class ;
                                                                          owl:unionOf ( <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration>
                                                                                        bto:WeatherData
                                                                                      )
                                                                        ] ;
                                                            rdfs:range <http://www.wurvoc.org/vocabularies/om-1.8/Unit_of_measure> .


###  https://w3id.org/brainteaser/ontology/schema/APConcentrationTime
bto:APConcentrationTime rdf:type owl:ObjectProperty ;
                        rdfs:domain [ rdf:type owl:Class ;
                                      owl:unionOf ( <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration>
                                                    bto:WeatherData
                                                  )
                                    ] ;
                        rdfs:range time:Instant ;
                        rdfs:comment "It defines the relationship between air pollution conentration individuals and their time of recording."@en ;
                        rdfs:label "APConcentrationTime"@en .


###  https://w3id.org/brainteaser/ontology/schema/administration
bto:administration rdf:type owl:ObjectProperty ;
                   rdfs:domain bto:TherapeuticTreatment ;
                   rdfs:range bto:Administration ;
                   rdfs:comment "It defines the relationship between a therapeutic treatment and the specific administration details."@en ;
                   rdfs:label "administration"@en .


###  https://w3id.org/brainteaser/ontology/schema/adverseReaction
bto:adverseReaction rdf:type owl:ObjectProperty ;
                    rdfs:domain bto:EndTherapyReason ;
                    rdfs:range bto:AdverseDrugReaction ;
                    rdfs:comment "It defines the relationship between The end therapy reason and the adverse reaction occurred."@en ;
                    rdfs:label "adverseReaction"@en .


###  https://w3id.org/brainteaser/ontology/schema/anatomicalLocation
bto:anatomicalLocation rdf:type owl:ObjectProperty ;
                       rdfs:domain [ rdf:type owl:Class ;
                                     owl:unionOf ( bto:ClinicalEvaluation
                                                   bto:DiagnosticImaging
                                                   bto:Onset
                                                   bto:SurgicalProcedure
                                                   bto:Trauma
                                                 )
                                   ] ;
                       rdfs:range bto:AnatomicalSite ;
                       rdfs:comment "It defines the location of a trauma, onset, surgical procedure or diagnostic imaging."@en ;
                       rdfs:label "anatomicalLocation"@en .


###  https://w3id.org/brainteaser/ontology/schema/birthplace
bto:birthplace rdf:type owl:ObjectProperty ;
               rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
               rdfs:range bto:Place ;
               rdfs:comment "It defines the relationship between a person and his or her birthplace."@en ;
               rdfs:label "birthplace"@en .


###  https://w3id.org/brainteaser/ontology/schema/coexistingPregnancy
bto:coexistingPregnancy rdf:type owl:ObjectProperty ;
                        rdfs:domain bto:Relapse ;
                        rdfs:range bto:Pregnancy ;
                        rdfs:comment "It defines the relationship between a relapse and a co-occurring pregnancy."@en ;
                        rdfs:label "coexistingPregnancy"@en .


###  https://w3id.org/brainteaser/ontology/schema/conductedInClinic
bto:conductedInClinic rdf:type owl:ObjectProperty ;
                      rdfs:domain bto:ClinicalTrial ;
                      rdfs:range bto:ClinicsAndHospitals ;
                      rdfs:comment "It defines the relationship between a clinical trial and a clinic or hospital. In particular, a clinical trial is conducted in a clinic or hospital."@en ;
                      rdfs:label "conductedInClinic"@en .


###  https://w3id.org/brainteaser/ontology/schema/confirmedPregnancy
bto:confirmedPregnancy rdf:type owl:ObjectProperty ;
                       rdfs:domain bto:EndTherapyReason ;
                       rdfs:range bto:Pregnancy ;
                       rdfs:comment "It defines the relationship between the end therapy reason and a pregnancy, meaning the therapeutic treatment was interrupted due to a confirmed pregnancy."@en ;
                       rdfs:label "confirmedPregnancy"@en .


###  https://w3id.org/brainteaser/ontology/schema/consists
bto:consists rdf:type owl:ObjectProperty ;
             rdfs:domain bto:Event ;
             rdfs:range bto:InterventionOrProcedure ;
             rdfs:comment "It defines the relationship between an event and an intervetion or procedure. In particular, an event could consist in an intervention or procedure."@en ;
             rdfs:label "consists"@en .


###  https://w3id.org/brainteaser/ontology/schema/coveredPlace
bto:coveredPlace rdf:type owl:ObjectProperty ;
                 rdfs:domain <http://purl.oclc.org/NET/ssnx/ssn#SensingDevice> ;
                 rdfs:range bto:Place ;
                 rdfs:comment "It defines the relationship between the sensing device for environmental data and the covered place."@en ;
                 rdfs:label "coveredPlace"@en .


###  https://w3id.org/brainteaser/ontology/schema/determinedBy
bto:determinedBy rdf:type owl:ObjectProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:Comorbidity ;
                 rdfs:range bto:DiseaseDisorderOrFinding ;
                 rdfs:comment "It defines the relationship between a comorbidity and the disease that determines it."@en ;
                 rdfs:label "determinedBy"@en .


###  https://w3id.org/brainteaser/ontology/schema/enrolledIn
bto:enrolledIn rdf:type owl:ObjectProperty ;
               rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
               rdfs:range bto:ClinicalTrialParticipation ;
               rdfs:comment "It defines the relationship between a person and a clinical trial participation. In particular, a person can be enrolled in a clinical trial participation."@en ;
               rdfs:label "enrolledIn"@en .


###  https://w3id.org/brainteaser/ontology/schema/filledAppQuestionnaire
bto:filledAppQuestionnaire rdf:type owl:ObjectProperty ;
                           rdfs:domain bto:Event ;
                           rdfs:range bto:AppQuestionnaire ;
                           rdfs:comment "Links each app questionnaire to the event in which it was filled."@en ;
                           rdfs:label "filledAppQuestionnaire"@en .


###  https://w3id.org/brainteaser/ontology/schema/hasDisease
bto:hasDisease rdf:type owl:ObjectProperty ;
               rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
               rdfs:range bto:DiseaseDisorderOrFinding ;
               rdfs:comment "It defines the relationship between a person and a disease which he or she suffers from."@en ;
               rdfs:label "hasDisease"@en .


###  https://w3id.org/brainteaser/ontology/schema/hasEthnicity
bto:hasEthnicity rdf:type owl:ObjectProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:Patient ;
                 rdfs:range bto:Group ;
                 rdfs:comment "It defines the patient's ethnicity. For instance, we say that: :Peter :hasEthnicity _:b . _:b a Group (social concept); a skos:Concept."@en ;
                 rdfs:label "hasEthnicity"@en .


###  https://w3id.org/brainteaser/ontology/schema/hasKinship
bto:hasKinship rdf:type owl:ObjectProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:Patient ;
               rdfs:range bto:Kinship ;
               rdfs:comment "It defines the relation between a patient and a kinship. For instance, we say that: :Peter :hasKinship _:b . _:b a Kinship; :hasKinshipType http://aunt. http://aunt a KinshipType; a skos:Concept."@en ;
               rdfs:label "hasKinship"@en ;
               skos:note "This property is functional because we refer only to biological kinship thus a person can only have one biological kinship with a specific person."@en .


###  https://w3id.org/brainteaser/ontology/schema/hasKinshipType
bto:hasKinshipType rdf:type owl:ObjectProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:Kinship ;
                   rdfs:range bto:KinshipType ;
                   rdfs:comment "It defines the relation between a Kinship and a KinshipType. For instance, we say that: :Peter :hasKinship _:b . _:b a Kinship; :hasKinshipType http://aunt. http://aunt a KinshipType; a skos:Concept."@en ;
                   rdfs:label "hasKinshipType"@en .


###  https://w3id.org/brainteaser/ontology/schema/hasOccupation
bto:hasOccupation rdf:type owl:ObjectProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:Patient ;
                  rdfs:range bto:Occupation ;
                  rdfs:comment "It defines the relationship between a patient and his or her occupation."@en ;
                  rdfs:label "hasOccupation"@en .


###  https://w3id.org/brainteaser/ontology/schema/hasRegisteredActivity
bto:hasRegisteredActivity rdf:type owl:ObjectProperty ;
                          rdfs:domain bto:Event ;
                          rdfs:range bto:Activity ;
                          rdfs:comment "It defines the relationsihip between an event and an activity. In particular, during an event a specific type of activity can be registered."@en ;
                          rdfs:label "hasRegisteredActivity"@en .


###  https://w3id.org/brainteaser/ontology/schema/hasRegisteredCondition
bto:hasRegisteredCondition rdf:type owl:ObjectProperty ;
                           rdfs:domain bto:Event ;
                           rdfs:range bto:Condition ;
                           rdfs:comment "It defines the relationsihip between an event and a comorbidity. In particular, during an event a preexisting condition can be registered."@en ;
                           rdfs:label "hasRegisteredCondition"@en .


###  https://w3id.org/brainteaser/ontology/schema/inClinicalTrial
bto:inClinicalTrial rdf:type owl:ObjectProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:ClinicalTrialParticipation ;
                    rdfs:range bto:ClinicalTrial ;
                    rdfs:comment "It defines the relationship between a clinical trial participation and a clinical trial. In particular, a clinical trial participation refers to a clinical trial."@en ;
                    rdfs:label "inClinicalTrial" .


###  https://w3id.org/brainteaser/ontology/schema/inKinshipWith
bto:inKinshipWith rdf:type owl:ObjectProperty ;
                  rdfs:domain bto:Kinship ;
                  rdfs:range <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
                  rdfs:comment "The relationship of kinship between a patient with another Person (who might also be a Patient)"^^xsd:string ;
                  rdfs:label "inKinshipWith"@en .


###  https://w3id.org/brainteaser/ontology/schema/isAboutDisease
bto:isAboutDisease rdf:type owl:ObjectProperty ;
                   rdfs:domain bto:ClinicalTrial ;
                   rdfs:range bto:DiseaseDisorderOrFinding ;
                   rdfs:comment "It defines the relationship between a clinical trial and the disease studied in it."@en ;
                   rdfs:label "isAboutDisease"@en .


###  https://w3id.org/brainteaser/ontology/schema/menstrualCycle
bto:menstrualCycle rdf:type owl:ObjectProperty ;
                   rdfs:domain bto:Patient ;
                   rdfs:range bto:MenstrualCycle ;
                   rdfs:comment "Links a patient to the information about her menstrual cycle."@en ;
                   rdfs:label "menstrualCycle"@en .


###  https://w3id.org/brainteaser/ontology/schema/observedResult
bto:observedResult rdf:type owl:ObjectProperty ;
                   rdfs:domain bto:HematologyTest ;
                   rdfs:range bto:LaboratoryTestResult ;
                   rdfs:comment "It defines the relationship between an hematology test and the observed laboratory results."@en ;
                   rdfs:label "observedResult"@en .


###  https://w3id.org/brainteaser/ontology/schema/onGene
bto:onGene rdf:type owl:ObjectProperty ;
           rdfs:domain bto:GeneticTesting ;
           rdfs:range bto:Gene ;
           rdfs:comment "It defnies the relationship between a genetic testing and a gene. In particular, a genetic testing looks for some genetic mutations on a gene."@en ;
           rdfs:label "onGene"@en .


###  https://w3id.org/brainteaser/ontology/schema/ownsSensingDevice
bto:ownsSensingDevice rdf:type owl:ObjectProperty ;
                      rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
                      rdfs:range <http://purl.oclc.org/NET/ssnx/ssn#SensingDevice> ;
                      rdfs:comment "Links each person to the sensing device they are carrying."@en ;
                      rdfs:label "ownsSensingDevice"@en .


###  https://w3id.org/brainteaser/ontology/schema/performedTreatment
bto:performedTreatment rdf:type owl:ObjectProperty ;
                       rdfs:domain bto:TherapeuticProcedure ;
                       rdfs:range bto:TherapeuticTreatment ;
                       rdfs:comment "It defines the relationship between the therapeutic procedure and the perfomed therapeutic treatments."@en ;
                       rdfs:label "performedTreatment"@en .


###  https://w3id.org/brainteaser/ontology/schema/pharmacologicSubstance
bto:pharmacologicSubstance rdf:type owl:ObjectProperty ;
                           rdfs:domain bto:TherapeuticTreatment ;
                           rdfs:range bto:PharmacologicSubstance ;
                           rdfs:comment "It defines the relationship between a therapeutic treatment and the employed pharmacologic subastance."@en ;
                           rdfs:label "pharmacologicSubstance"@en .


###  https://w3id.org/brainteaser/ontology/schema/placeLocation
bto:placeLocation rdf:type owl:ObjectProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:Residence ;
                  rdfs:range bto:Place ;
                  rdfs:comment "It defines the relationship between a patient's residence and its location."@en ;
                  rdfs:label "placeLocation"@en .


###  https://w3id.org/brainteaser/ontology/schema/pregnancy
bto:pregnancy rdf:type owl:ObjectProperty ;
              rdfs:domain bto:Event ;
              rdfs:range bto:Pregnancy ;
              rdfs:comment "It defines the relationship between an event and a pregnancy that can be registrered during the event."@en ;
              rdfs:label "pregnancy"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapse
bto:relapse rdf:type owl:ObjectProperty ;
            rdfs:domain bto:Event ;
            rdfs:range bto:Relapse ;
            rdfs:comment "It defines the relationship between an event and a relapse that can be registered during the event."@en ;
            rdfs:label "relapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/requiredMRI
bto:requiredMRI rdf:type owl:ObjectProperty ;
                rdfs:domain bto:Relapse ;
                rdfs:range bto:MRI ;
                rdfs:comment "It defines the relationship between a relapse and a MRI that has been required."@en ;
                rdfs:label "requiredMRI"@en .


###  https://w3id.org/brainteaser/ontology/schema/residence
bto:residence rdf:type owl:ObjectProperty ;
              rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
              rdfs:range bto:Residence ;
              rdfs:comment "It defines the relationship between a person and his or her residence."@en ;
              rdfs:label "residence"@en .


###  https://w3id.org/brainteaser/ontology/schema/surgicalType
bto:surgicalType rdf:type owl:ObjectProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:SurgicalProcedure ;
                 rdfs:range bto:SurgicalType ;
                 rdfs:comment "It defines the realtionship between the surgical procedure and the specific type of surgical procedure."@en ;
                 rdfs:label "surgicalType"@en .


###  https://w3id.org/brainteaser/ontology/schema/tested
bto:tested rdf:type owl:ObjectProperty ;
           rdfs:domain bto:Patient ;
           rdfs:range bto:GeneticTesting ;
           rdfs:comment "It defines the relationship betwen a patient and a genetic testing. In particular, a patient can be tested for genetic mutations."@en ;
           rdfs:label "tested"@en .


###  https://w3id.org/brainteaser/ontology/schema/testedForOligoclonalBands
bto:testedForOligoclonalBands rdf:type owl:ObjectProperty ,
                                       owl:FunctionalProperty ;
                              rdfs:domain bto:CSFAnalysis ;
                              rdfs:range bto:OligoclonalBands ;
                              rdfs:comment "It defines the relationship between a CSF Analysis and a test for the presence of oligoclonal bands."@en ;
                              rdfs:label "testedForOligoclonalBands"@en .


###  https://w3id.org/brainteaser/ontology/schema/therapyType
bto:therapyType rdf:type owl:ObjectProperty ;
                rdfs:domain bto:TherapeuticTreatment ;
                rdfs:range bto:TherapeuticProcedureType ;
                rdfs:comment "It defines the relationship between the therapeutic treatment and the type of therapeutic procedure that has been administered."@en ;
                rdfs:label "therapyType"@en .


###  https://w3id.org/brainteaser/ontology/schema/trauma
bto:trauma rdf:type owl:ObjectProperty ;
           rdfs:domain bto:Event ;
           rdfs:range bto:Trauma ;
           rdfs:comment "It defines the relationship between an event and a trauma that can be registered during the event."@en ;
           rdfs:label "trauma"@en .


###  https://w3id.org/brainteaser/ontology/schema/undergo
bto:undergo rdf:type owl:ObjectProperty ;
            rdfs:domain bto:Patient ;
            rdfs:range bto:Event ;
            rdfs:comment "It defines the relationship between patient and event. In particular, a patient can undergo some events."@en ;
            rdfs:label "undergo"@en .


#################################################################
#    Data properties
#################################################################

###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q1
bto:ALSFRSR_Q1 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( xsd:integer
                                          [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "Detectable speech disturbance"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Intelligible with repeating"@en ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "Normal speech process"@en ;
                                                                              rdf:rest rdf:nil
                                                                            ]
                                                                 ]
                                                      ]
                                          ]
                                        )
                          ] ;
               dcterms:conformsTo UMLS:C4298336 ;
               rdfs:comment "Q1: Speech"@en ;
               rdfs:label "ALSFRSR_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q10
bto:ALSFRSR_Q10 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:SelfALSFRSR ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:unionOf ( xsd:integer
                                           [ rdf:type rdfs:Datatype ;
                                             owl:oneOf [ rdf:type rdf:List ;
                                                         rdf:first "None"@en ;
                                                         rdf:rest [ rdf:type rdf:List ;
                                                                    rdf:first "Occurs at rest: difficulty breathing when either sitting or lying"@en ;
                                                                    rdf:rest [ rdf:type rdf:List ;
                                                                               rdf:first "Occurs with one or more of the following: eating, bathing, dressing"@en ;
                                                                               rdf:rest rdf:nil
                                                                             ]
                                                                  ]
                                                       ]
                                           ]
                                         )
                           ] ;
                dcterms:conformsTo UMLS:C4298328 ;
                rdfs:comment "Q10: Dyspnea"@en ;
                rdfs:label "ALSFRSR_Q10"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q10alt
bto:ALSFRSR_Q10alt rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:SelfALSFRSR ;
                   rdfs:range [ rdf:type rdfs:Datatype ;
                                owl:oneOf [ rdf:type rdf:List ;
                                            rdf:first "no change"@en ;
                                            rdf:rest [ rdf:type rdf:List ;
                                                       rdf:first "shortness of breath at rest while either sitting or lying down"@en ;
                                                       rdf:rest [ rdf:type rdf:List ;
                                                                  rdf:first "shortness of breath only with walking"@en ;
                                                                  rdf:rest [ rdf:type rdf:List ;
                                                                             rdf:first "shortness of breath with minimal exertion (i.e. talking, eating, bathing or dressing)"@en ;
                                                                             rdf:rest [ rdf:type rdf:List ;
                                                                                        rdf:first "significant shortness of breath (all of the time) and considering using mechanical ventilation"@en ;
                                                                                        rdf:rest rdf:nil
                                                                                      ]
                                                                           ]
                                                                ]
                                                     ]
                                          ]
                              ] ;
                   rdfs:comment "Do you experience shortness of breath or have difficulty breathing?"@en ;
                   rdfs:label "ALSFRSR_Q10alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q11
bto:ALSFRSR_Q11 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:SelfALSFRSR ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:unionOf ( xsd:integer
                                           [ rdf:type rdfs:Datatype ;
                                             owl:oneOf [ rdf:type rdf:List ;
                                                         rdf:first "Needs extra pillows in order to sleep (more than two)"@en ;
                                                         rdf:rest [ rdf:type rdf:List ;
                                                                    rdf:first "None"@en ;
                                                                    rdf:rest [ rdf:type rdf:List ;
                                                                               rdf:first "Some difficulty sleeping at night due to shortness of breath, does not routinely use more than two pillows"@en ;
                                                                               rdf:rest [ rdf:type rdf:List ;
                                                                                          rdf:first "Unable to sleep without mechanical assistance"@en ;
                                                                                          rdf:rest rdf:nil
                                                                                        ]
                                                                             ]
                                                                  ]
                                                       ]
                                           ]
                                         )
                           ] ;
                dcterms:conformsTo UMLS:C4298327 ;
                rdfs:comment "Q11: Orthopnea"@en ;
                rdfs:label "ALSFRSR_Q11"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q11alt
bto:ALSFRSR_Q11alt rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:SelfALSFRSR ;
                   rdfs:range [ rdf:type rdfs:Datatype ;
                                owl:oneOf [ rdf:type rdf:List ;
                                            rdf:first "Unable to sleep without mechanical assistance"@en ;
                                            rdf:rest [ rdf:type rdf:List ;
                                                       rdf:first "no change"@en ;
                                                       rdf:rest [ rdf:type rdf:List ;
                                                                  rdf:first "occasional shortness of breath while lying on back but don't routinely use more that two (2) pillows to sleep"@en ;
                                                                  rdf:rest [ rdf:type rdf:List ;
                                                                             rdf:first "shortness of breath while lying on back and require more than two pillows (or an equivalent) to sleep"@en ;
                                                                             rdf:rest rdf:nil
                                                                           ]
                                                                ]
                                                     ]
                                          ]
                              ] ;
                   rdfs:comment "Do you experience shortness of breath or have difficulty breathing while lying down on your back?"@en ;
                   rdfs:label "ALSFRSR_Q11alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q12
bto:ALSFRSR_Q12 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:SelfALSFRSR ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:unionOf ( xsd:integer
                                           [ rdf:type rdfs:Datatype ;
                                             owl:oneOf [ rdf:type rdf:List ;
                                                         rdf:first "Continuous use of BiPAP during the night"@en ;
                                                         rdf:rest [ rdf:type rdf:List ;
                                                                    rdf:first "Intermittent use of BiPAP"@en ;
                                                                    rdf:rest [ rdf:type rdf:List ;
                                                                               rdf:first "None"@en ;
                                                                               rdf:rest rdf:nil
                                                                             ]
                                                                  ]
                                                       ]
                                           ]
                                         )
                           ] ;
                dcterms:conformsTo UMLS:C4298326 ;
                rdfs:comment "Q12: Respiratory Insufficiency"@en ;
                rdfs:label "ALSFRSR_Q12"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q12alt
bto:ALSFRSR_Q12alt rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:SelfALSFRSR ;
                   rdfs:range [ rdf:type rdfs:Datatype ;
                                owl:oneOf [ rdf:type rdf:List ;
                                            rdf:first "continuous use of BiPAP at night"@en ;
                                            rdf:rest [ rdf:type rdf:List ;
                                                       rdf:first "continuous use of BiPAP at night and during the day (nearly 24 hours per day)"@en ;
                                                       rdf:rest [ rdf:type rdf:List ;
                                                                  rdf:first "intermittent use of BiPAP"@en ;
                                                                  rdf:rest [ rdf:type rdf:List ;
                                                                             rdf:first "mechanical ventilation by intubation or tracheostomy"@en ;
                                                                             rdf:rest [ rdf:type rdf:List ;
                                                                                        rdf:first "no respiratory support"@en ;
                                                                                        rdf:rest rdf:nil
                                                                                      ]
                                                                           ]
                                                                ]
                                                     ]
                                          ]
                              ] ;
                   rdfs:comment "Do you require respiratory (breathing) support?"@en ;
                   rdfs:label "ALSFRSR_Q12alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q1alt
bto:ALSFRSR_Q1alt rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SelfALSFRSR ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "no change"@en ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "noticeable speech difference"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "speech has changed; asked often to repeat words or phrases"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "speech has changed; sometimes need the use of alternative communication methods (i.e. computer, writing pad, letter board or eye chart)"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "unable to communicate verbally"@en ;
                                                                                       rdf:rest rdf:nil
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Have you noticed any changes in your speech?"@en ;
                  rdfs:label "ALSFRSR_Q1alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q2
bto:ALSFRSR_Q2 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( xsd:integer
                                          [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "Moderately excessive saliva; may have minimal drooling"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Normal"@en ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "Slight but definite excess of saliva in mouth; may have night time drooling"@en ;
                                                                              rdf:rest rdf:nil
                                                                            ]
                                                                 ]
                                                      ]
                                          ]
                                        )
                          ] ;
               dcterms:conformsTo UMLS:C4298335 ;
               rdfs:comment "Q2: Salivation"@en ;
               rdfs:label "ALSFRSR_Q2"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q2alt
bto:ALSFRSR_Q2alt rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SelfALSFRSR ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "marked amounts of excessive saliva with some daytime drooling"@en ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "marked excessive saliva with marked drooling requiring a constant tissue or handkerchief"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "moderate amounts of excessive saliva with or without minimal day time drooling"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "no change"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "slight but definite excess of saliva with or without night time drooling"@en ;
                                                                                       rdf:rest rdf:nil
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Have you noticed any changes (increases) in the amount of saliva in your mouth (regardless of any medication use)?"@en ;
                  rdfs:label "ALSFRSR_Q2alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q3
bto:ALSFRSR_Q3 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( xsd:integer
                                          [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "Early eating problems - occasional choking"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Normal eating habits"@en ;
                                                                   rdf:rest rdf:nil
                                                                 ]
                                                      ]
                                          ]
                                        )
                          ] ;
               dcterms:conformsTo UMLS:C4298334 ;
               rdfs:comment "Q3: Swallowing"@en ;
               rdfs:label "ALSFRSR_Q3"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q3alt
bto:ALSFRSR_Q3alt rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SelfALSFRSR ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "do not eat anything by mouth and receive all nutrition through a feeding tube (PEG)"@en ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "no changes (all foods and liquids)"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "some changes in swallowing or occasional choking episodes (including coughing during swallowing)"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "unable to eat all consistencies of food and have modified the consistency of foods eaten"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "use a feeding tube (PEG) to supplement what is eaten by mouth"@en ;
                                                                                       rdf:rest rdf:nil
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Have there been any changes in your ability to swallow?"@en ;
                  rdfs:label "ALSFRSR_Q3alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q4
bto:ALSFRSR_Q4 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( xsd:integer
                                          [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "No words are legible, but can still grip pen"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Normal"@en ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "Not all words are legible"@en ;
                                                                              rdf:rest [ rdf:type rdf:List ;
                                                                                         rdf:first "Slow"@en ;
                                                                                         rdf:rest rdf:nil
                                                                                       ]
                                                                            ]
                                                                 ]
                                                      ]
                                          ]
                                        )
                          ] ;
               dcterms:conformsTo UMLS:C4298333 ;
               rdfs:comment "Q4:Handwriting"@en ;
               rdfs:label "ALSFRSR_Q4"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q4alt
bto:ALSFRSR_Q4alt rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SelfALSFRSR ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "able to hold a pen but unable to write"@en ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "no changes"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "not all words are legible"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "slower and/or sloppier but all the words are legible"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "unable to hold a pen"@en ;
                                                                                       rdf:rest rdf:nil
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Has your handwriting changed? Please choose the best answer that describes your  handwriting with your dominant (usual) hand without a cuff or brace."@en ;
                  rdfs:label "ALSFRSR_Q4alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q5
bto:ALSFRSR_Q5 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range xsd:integer ;
               rdfs:comment "Q5: Cutting Food and Handling Utensils (with or without gastrostomy)."@en ;
               rdfs:label "ALSFRSR_Q5"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q5A
bto:ALSFRSR_Q5A rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:SelfALSFRSR ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Can cut most foods (> 50%), although slow and clumsy; some help needed"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Food must be cut by someone, but can still feed slowly"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Normal"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Somewhat slow and clumsy, but no help needed"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C4285407 ;
                rdfs:comment "Q5A: Cutting Food and Handling Utensils (without gastrostomy)"@en ;
                rdfs:label "ALSFRSR_Q5A"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q5Aalt
bto:ALSFRSR_Q5Aalt rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:SelfALSFRSR ;
                   rdfs:range [ rdf:type rdfs:Datatype ;
                                owl:oneOf [ rdf:type rdf:List ;
                                            rdf:first "food must be cut by someone else but can feed slowly without assistance"@en ;
                                            rdf:rest [ rdf:type rdf:List ;
                                                       rdf:first "needs to be fed"@en ;
                                                       rdf:rest [ rdf:type rdf:List ;
                                                                  rdf:first "no change"@en ;
                                                                  rdf:rest [ rdf:type rdf:List ;
                                                                             rdf:first "sometimes need help with cutting more difficult foods"@en ;
                                                                             rdf:rest [ rdf:type rdf:List ;
                                                                                        rdf:first "somewhat slow and clumsy (or different than before) but no assistance or  adaptive equipment"@en ;
                                                                                        rdf:rest rdf:nil
                                                                                      ]
                                                                           ]
                                                                ]
                                                     ]
                                          ]
                              ] ;
                   rdfs:comment "Cutting food and handling utensils"@en ;
                   rdfs:label "ALSFRSR_Q5Aalt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q5B
bto:ALSFRSR_Q5B rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:SelfALSFRSR ;
                rdfs:range rdf:PlainLiteral ;
                dcterms:conformsTo UMLS:C4298332 ;
                rdfs:comment "Q5B: Cutting Food and Handling Utensils (with gastrostomy)"@en ;
                rdfs:label "ALSFRSR_Q5B"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q5Balt
bto:ALSFRSR_Q5Balt rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:SelfALSFRSR ;
                   rdfs:range [ rdf:type rdfs:Datatype ;
                                owl:oneOf [ rdf:type rdf:List ;
                                            rdf:first "require assistance with closures and fasteners"@en ;
                                            rdf:rest [ rdf:type rdf:List ;
                                                       rdf:first "unable to perform any of the manipulations"@en ;
                                                       rdf:rest rdf:nil
                                                     ]
                                          ]
                              ] ;
                   rdfs:comment "Using a feeding tube (PEG)"@en ;
                   rdfs:label "ALSFRSR_Q5Balt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q6
bto:ALSFRSR_Q6 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( xsd:integer
                                          [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "Independent; Can complete self-care with effort or decreased efficiency"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Intermittent assistance or substitute methods"@en ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "Needs attendant for self-care"@en ;
                                                                              rdf:rest [ rdf:type rdf:List ;
                                                                                         rdf:first "Normal function"@en ;
                                                                                         rdf:rest rdf:nil
                                                                                       ]
                                                                            ]
                                                                 ]
                                                      ]
                                          ]
                                        )
                          ] ;
               dcterms:conformsTo UMLS:C4298331 ;
               rdfs:comment "Q6: Dressing and Hygiene"@en ;
               rdfs:label "ALSFRSR_Q6"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q6alt
bto:ALSFRSR_Q6alt rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SelfALSFRSR ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "do not perform self-care activities and completely dependent on caregiver"@en ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "no change"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "perform self-care activities without assistance but with increased effort or decreased efficiency"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "require daily assistance"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "require intermittent assistance or use different methods (i.e. sit down to get dressed, fasten buttons with a fastener or your non-dominant hand)"@en ;
                                                                                       rdf:rest rdf:nil
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Has your ability to dress and perform self-care activities (i.e. bathing, teeth brushing, shaving, combing your hair, other hygienic activities) changed?"@en ;
                  rdfs:label "ALSFRSR_Q6alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q7
bto:ALSFRSR_Q7 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( xsd:integer
                                          [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "Can turn alone, or adjust sheets, but with great difficulty"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Normal function"@en ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "Somewhat slow and clumsy, but no help needed"@en ;
                                                                              rdf:rest rdf:nil
                                                                            ]
                                                                 ]
                                                      ]
                                          ]
                                        )
                          ] ;
               dcterms:conformsTo UMLS:C4285576 ;
               rdfs:comment "Q7: Truning in Bed and Adjusting Bed Clothes"@en ;
               rdfs:label "ALSFRSR_Q7"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q7alt
bto:ALSFRSR_Q7alt rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SelfALSFRSR ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "can initiate turning in bed or adjusting the bed clothes but require assistance to complete the task"@en ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "can turn in bed and adjust the bed clothes without assistance but it is slower or more clumsy"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "can turn in bed or adjust the bedclothes without assistance but with great difficulty"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "helpless in bed"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "no change"@en ;
                                                                                       rdf:rest rdf:nil
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Has your ability to turn in bed and adjust the bed clothes (i.e. cover yourself with the sheet or blanket) changed?"@en ;
                  rdfs:label "ALSFRSR_Q7alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q8
bto:ALSFRSR_Q8 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( xsd:integer
                                          [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "Early ambulation difficulties"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Non-ambulatory functional movement only"@en ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "Normal"@en ;
                                                                              rdf:rest [ rdf:type rdf:List ;
                                                                                         rdf:first "Walks with assistance"@en ;
                                                                                         rdf:rest rdf:nil
                                                                                       ]
                                                                            ]
                                                                 ]
                                                      ]
                                          ]
                                        )
                          ] ;
               dcterms:conformsTo UMLS:C4298330 ;
               rdfs:comment "Q8: Walking"@en ;
               rdfs:label "ALSFRSR_Q8"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q8alt
bto:ALSFRSR_Q8alt rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SelfALSFRSR ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "can move legs or stand up but unable to walk from room to room"@en ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "cannot walk or move my legs"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "no change"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "require assistance to walk (i.e. cane, walker, foot brace or hand held assistance)"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "walking has changed but do not require any assistance or devices (i.e. foot brace, cane, walker)"@en ;
                                                                                       rdf:rest rdf:nil
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Has your ability to walk changed?"@en ;
                  rdfs:label "ALSFRSR_Q8alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q9
bto:ALSFRSR_Q9 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SelfALSFRSR ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( xsd:integer
                                          [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "Cannot do"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Mild unsteadiness or fatigue"@en ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "Needs assistance"@en ;
                                                                              rdf:rest [ rdf:type rdf:List ;
                                                                                         rdf:first "Normal"@en ;
                                                                                         rdf:rest [ rdf:type rdf:List ;
                                                                                                    rdf:first "Slow"@en ;
                                                                                                    rdf:rest rdf:nil
                                                                                                  ]
                                                                                       ]
                                                                            ]
                                                                 ]
                                                      ]
                                          ]
                                        )
                          ] ;
               dcterms:conformsTo UMLS:C4298329 ;
               rdfs:comment "Q9: Climbing Stairs"@en ;
               rdfs:label "ALSFRSR_Q9"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRSR_Q9alt
bto:ALSFRSR_Q9alt rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SelfALSFRSR ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "cannot climb stairs"@en ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "no change"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "require assistance (i.e. using the handrail, cane or person)"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "slower"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "unsteady and/or more fatigued"@en ;
                                                                                       rdf:rest rdf:nil
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Has your ability to climb stairs changed?"@en ;
                  rdfs:label "ALSFRSR_Q9alt"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRS_R_WHO_COMPLETED
bto:ALSFRS_R_WHO_COMPLETED rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:SelfALSFRSR ;
                           rdfs:range [ rdf:type rdfs:Datatype ;
                                        owl:oneOf [ rdf:type rdf:List ;
                                                    rdf:first "Caregiver alone"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Patient"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Patient with assistance"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Patient with assistance from caregiver or family member"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                      ] ;
                           rdfs:comment "Please indicate who completed this survey"@en ;
                           rdfs:label "ALSFRS_R_WHO_COMPLETED"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q1
bto:DYMUS_Q1 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you have difficulties swallowing solid food (such as meat, bread, and the like)?"@en ;
             rdfs:label "DYMUS_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q10
bto:DYMUS_Q10 rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:DYMUS ;
              rdfs:range xsd:boolean ;
              rdfs:comment "Do you have weight loss?"@en ;
              rdfs:label "DYMUS_Q10"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q2
bto:DYMUS_Q2 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you have difficulties swallowing liquids (such as water, milk, and the like)?"@en ;
             rdfs:label "DYMUS_Q2"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q3
bto:DYMUS_Q3 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you have a globus sensation in your throat during swallowing?"@en ;
             rdfs:label "DYMUS_Q3"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q4
bto:DYMUS_Q4 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you have food sticking in your throat?"@en ;
             rdfs:label "DYMUS_Q4"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q5
bto:DYMUS_Q5 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you cough or do you have a choking sensation after ingesting solid foods?"@en ;
             rdfs:label "DYMUS_Q5"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q6
bto:DYMUS_Q6 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you cough or do you have a choking sensation after ingesting liquids?"@en ;
             rdfs:label "DYMUS_Q6"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q7
bto:DYMUS_Q7 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you need to swallow several times before completely swallowing solid food?"@en ;
             rdfs:label "DYMUS_Q7"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q8
bto:DYMUS_Q8 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you need to cut food in small pieces before swallowing?"@en ;
             rdfs:label "DYMUS_Q8"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS_Q9
bto:DYMUS_Q9 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:DYMUS ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Do you need to take many sips before completely swallowing liquid?"@en ;
             rdfs:label "DYMUS_Q9"@en .


###  https://w3id.org/brainteaser/ontology/schema/EQ5D5L_Q1
bto:EQ5D5L_Q1 rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:EQ5D5L ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "I am unable to walk about"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "I have moderate problems in walking about"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "I have no problems in walking about"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "I have severe problems in walking about"@en ;
                                                                        rdf:rest [ rdf:type rdf:List ;
                                                                                   rdf:first "I have slight problems in walking about"@en ;
                                                                                   rdf:rest rdf:nil
                                                                                 ]
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Mobility"@en ;
              rdfs:label "EQ5D5L_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/EQ5D5L_Q2
bto:EQ5D5L_Q2 rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:EQ5D5L ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "I am unable to wash or dress myself"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "I have moderate problems washing or dressing myself"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "I have no problems washing or dressing myself"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "I have severe problems washing or dressing myself"@en ;
                                                                        rdf:rest [ rdf:type rdf:List ;
                                                                                   rdf:first "I have slight problems washing or dressing myself"@en ;
                                                                                   rdf:rest rdf:nil
                                                                                 ]
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Self-care"@en ;
              rdfs:label "EQ5D5L_Q2"@en .


###  https://w3id.org/brainteaser/ontology/schema/EQ5D5L_Q3
bto:EQ5D5L_Q3 rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:EQ5D5L ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "I am unable to do my usual activities"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "I have moderate problems doing my usual activities"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "I have no problems doing my usual activities"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "I have severe problems doing my usual activities"@en ;
                                                                        rdf:rest [ rdf:type rdf:List ;
                                                                                   rdf:first "I have slight problems doing my usual activities"@en ;
                                                                                   rdf:rest rdf:nil
                                                                                 ]
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Usual activities"@en ;
              rdfs:label "EQ5D5L_Q3"@en .


###  https://w3id.org/brainteaser/ontology/schema/EQ5D5L_Q4
bto:EQ5D5L_Q4 rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:EQ5D5L ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "I have moderate pain or discomfort"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "I have no pain or discomfort"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "I have severe pain or discomfort"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "I have slight pain or discomfort"@en ;
                                                                        rdf:rest rdf:nil
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Pain/Discomfort"@en ;
              rdfs:label "EQ5D5L_Q4"@en .


###  https://w3id.org/brainteaser/ontology/schema/EQ5D5L_Q5
bto:EQ5D5L_Q5 rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:EQ5D5L ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "I am extremely anxious or depressed"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "I am moderately anxious or depressed"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "I am not anxious or depressed"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "I am severely anxious or depressed"@en ;
                                                                        rdf:rest [ rdf:type rdf:List ;
                                                                                   rdf:first "I am slightly anxious or depressed"@en ;
                                                                                   rdf:rest rdf:nil
                                                                                 ]
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Anxiety/Depression"@en ;
              rdfs:label "EQ5D5L_Q5"@en .


###  https://w3id.org/brainteaser/ontology/schema/EQ5D5L_Q6
bto:EQ5D5L_Q6 rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:EQ5D5L ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:onDatatype xsd:float ;
                           owl:withRestrictions ( [ xsd:minInclusive "0.0"^^xsd:float
                                                  ]
                                                  [ xsd:maxInclusive "100.0"^^xsd:float
                                                  ]
                                                )
                         ] ;
              rdfs:comment "Health today"@en ;
              rdfs:label "EQ5D5L_Q6"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q1
bto:HADS_Q1 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "A lot of the time"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "From time to time, occasionally"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Most of the time"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Not at all"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641379 ;
            rdfs:comment "I feel tense or 'wound up'"@en ;
            rdfs:label "HADS_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q10
bto:HADS_Q10 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:HADS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Definitely"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "I don't take as much care as I should"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "I may not take quite as much care"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "I take just as much care as ever"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3641388 ;
             rdfs:comment "I have lost interest in my appearance"@en ;
             rdfs:label "HADS_Q10"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q11
bto:HADS_Q11 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:HADS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Not at all"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not very much"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Quite a lot"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Very much indeed"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3641389 ;
             rdfs:comment "I feel restless as I have to be on the move"@en ;
             rdfs:label "HADS_Q11"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q12
bto:HADS_Q12 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:HADS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "As much as I ever did"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Definitely less than I used to"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Hardly at all"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rather less than I used to"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3641390 ;
             rdfs:comment "I look forward with enjoyment to things"@en ;
             rdfs:label "HADS_Q12"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q13
bto:HADS_Q13 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:HADS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Not at all"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not very often"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Quite often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Very often indeed"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3641391 ;
             rdfs:comment "I get sudden feelings of panic"@en ;
             rdfs:label "HADS_Q13"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q14
bto:HADS_Q14 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:HADS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Not often"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Often"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Sometimes"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Very seldom"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3641392 ;
             rdfs:comment "I can enjoy a good book or radio or TV program"@en ;
             rdfs:label "HADS_Q14"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q2
bto:HADS_Q2 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Definitely as much"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Hardly at all"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Not quite so much"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Only a little"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641380 ;
            rdfs:comment "I still enjoy the things I used to enjoy"@en ;
            rdfs:label "HADS_Q2"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q3
bto:HADS_Q3 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "A little, but it doesnt worry me"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Not at all"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Very definitely and quite badly"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Yes, but not too badly"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641381 ;
            rdfs:comment "I get a sort of frightened feeling as if something awful is about to happen"@en ;
            rdfs:label "HADS_Q3"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q4
bto:HADS_Q4 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "As much as I always could"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Definitely not so much now"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Not at all"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Not quite so much now"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641382 ;
            rdfs:comment "I can laugh and see the funny side of things"@en ;
            rdfs:label "HADS_Q4"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q5
bto:HADS_Q5 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "A great deal of the time"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "A lot of the time"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "From time to time, but not too often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Only occasionally"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641383 ;
            rdfs:comment "Worrying thoughts go through my mind"@en ;
            rdfs:label "HADS_Q5"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q6
bto:HADS_Q6 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Most of the time"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Not often"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Sometimes"@en ;
                                                           rdf:rest rdf:nil
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641384 ;
            rdfs:comment "I feel cheerful"@en ;
            rdfs:label "HADS_Q6"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q7
bto:HADS_Q7 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Definitely"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Not at all"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Not often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Usually"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641385 ;
            rdfs:comment "I can sit at ease and feel relaxed"@en ;
            rdfs:label "HADS_Q7"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q8
bto:HADS_Q8 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Nearly all the time"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Not at all"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Sometimes"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Very often"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641386 ;
            rdfs:comment "I feel as if I am slowed down"@en ;
            rdfs:label "HADS_Q8"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_Q9
bto:HADS_Q9 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:HADS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Not at all"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Occasionally"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Quite often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Very often"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3641387 ;
            rdfs:comment "I get a sort of frightened feeling like 'butterflies' in the stomach"@en ;
            rdfs:label "HADS_Q9"@en .


###  https://w3id.org/brainteaser/ontology/schema/IgGIndexCSF
bto:IgGIndexCSF rdf:type owl:DatatypeProperty ,
                         owl:FunctionalProperty ;
                rdfs:domain bto:CSFAnalysis ;
                rdfs:range xsd:float ;
                rdfs:comment "The IgG index is the ratio of the quotients for IgG and albumin (IgGcsf/IgGs)/(Albcsf/Albs). It is a quantitative analysis of the relationship between CSF IgG and serum IgG, divided by the same relationship for albumin. [Definition Source: Simonsen, Cecilia Smith et al. “The diagnostic value of IgG index versus oligoclonal bands in cerebrospinal fluid of patients with multiple sclerosis.” Multiple sclerosis journal - experimental, translational and clinical vol. 6,1 2055217319901291. 22 Jan. 2020]"@en ;
                rdfs:label "IgGIndexCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q1
bto:MFIS_Q1 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Almost always"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Never"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Rarely"@en ;
                                                                      rdf:rest [ rdf:type rdf:List ;
                                                                                 rdf:first "Sometimes"@en ;
                                                                                 rdf:rest rdf:nil
                                                                               ]
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829104 ;
            rdfs:comment "I have been less alert"@en ;
            rdfs:label "MFIS_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q10
bto:MFIS_Q10 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3827236 ;
             rdfs:comment "I have trouble maintaining physical effort for long periods"@en ;
             rdfs:label "MFIS_Q10"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q11
bto:MFIS_Q11 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829103 ;
             rdfs:comment "I have had difficulty making decisions"@en ;
             rdfs:label "MFIS_Q11"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q12
bto:MFIS_Q12 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829096 ;
             rdfs:comment "I have been less motivated to do anything that requires thinking"@en ;
             rdfs:label "MFIS_Q12"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q13
bto:MFIS_Q13 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829093 ;
             rdfs:comment "My muscles have felt weak"@en ;
             rdfs:label "MFIS_Q13"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q14
bto:MFIS_Q14 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829108 ;
             rdfs:comment "I have been physically uncomfortable"@en ;
             rdfs:label "MFIS_Q14"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q15
bto:MFIS_Q15 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829099 ;
             rdfs:comment "I have had trouble finishing tasks that require thinking"@en ;
             rdfs:label "MFIS_Q15"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q16
bto:MFIS_Q16 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829107 ;
             rdfs:comment "I have had difficulty organizing my thoughts when doing things at home or at work"@en ;
             rdfs:label "MFIS_Q16"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q17
bto:MFIS_Q17 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829098 ;
             rdfs:comment "I have been less able to complete tasks that require physical effort"@en ;
             rdfs:label "MFIS_Q17"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q18
bto:MFIS_Q18 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829092 ;
             rdfs:comment "My thinking has been slowed down"@en ;
             rdfs:label "MFIS_Q18"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q19
bto:MFIS_Q19 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829100 ;
             rdfs:comment "I have had trouble concentrating"@en ;
             rdfs:label "MFIS_Q19"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q2
bto:MFIS_Q2 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Almost always"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Never"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Rarely"@en ;
                                                                      rdf:rest [ rdf:type rdf:List ;
                                                                                 rdf:first "Sometimes"@en ;
                                                                                 rdf:rest rdf:nil
                                                                               ]
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829102 ;
            rdfs:comment "I have had difficulty paying attention for long periods of time"@en ;
            rdfs:label "MFIS_Q2"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q20
bto:MFIS_Q20 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829101 ;
             rdfs:comment "I have limited my physical activities"@en ;
             rdfs:label "MFIS_Q20"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q21
bto:MFIS_Q21 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:MFIS ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Almost always"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Never"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Often"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Rarely"@en ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "Sometimes"@en ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             dcterms:conformsTo UMLS:C3829091 ;
             rdfs:comment "I have needed to rest more often or for longer periods"@en ;
             rdfs:label "MFIS_Q21"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q3
bto:MFIS_Q3 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Never"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Often"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Rarely"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Sometimes"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829088 ;
            rdfs:comment "I have been unable to think clearly"@en ;
            rdfs:label "MFIS_Q3"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q4
bto:MFIS_Q4 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Never"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Often"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Rarely"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Sometimes"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829106 ;
            rdfs:comment "I have been clumsy and uncoordinated"@en ;
            rdfs:label "MFIS_Q4"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q5
bto:MFIS_Q5 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Almost always"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Never"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Rarely"@en ;
                                                                      rdf:rest [ rdf:type rdf:List ;
                                                                                 rdf:first "Sometimes"@en ;
                                                                                 rdf:rest rdf:nil
                                                                               ]
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829105 ;
            rdfs:comment "I have been forgetful"@en ;
            rdfs:label "MFIS_Q5"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q6
bto:MFIS_Q6 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Almost always"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Never"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Rarely"@en ;
                                                                      rdf:rest [ rdf:type rdf:List ;
                                                                                 rdf:first "Sometimes"@en ;
                                                                                 rdf:rest rdf:nil
                                                                               ]
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829090 ;
            rdfs:comment "I have had to pace myself in my physical activities"@en ;
            rdfs:label "MFIS_Q6"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q7
bto:MFIS_Q7 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Almost always"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Never"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Rarely"@en ;
                                                                      rdf:rest [ rdf:type rdf:List ;
                                                                                 rdf:first "Sometimes"@en ;
                                                                                 rdf:rest rdf:nil
                                                                               ]
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829097 ;
            rdfs:comment "I have been less motivated to do anything that requires physical effort"@en ;
            rdfs:label "MFIS_Q7"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q8
bto:MFIS_Q8 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Almost always"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Never"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Rarely"@en ;
                                                                      rdf:rest [ rdf:type rdf:List ;
                                                                                 rdf:first "Sometimes"@en ;
                                                                                 rdf:rest rdf:nil
                                                                               ]
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829095 ;
            rdfs:comment "I have been less motivated to participate in social activities"@en ;
            rdfs:label "MFIS_Q8"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS_Q9
bto:MFIS_Q9 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:MFIS ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Almost always"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Never"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Often"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Rarely"@en ;
                                                                      rdf:rest [ rdf:type rdf:List ;
                                                                                 rdf:first "Sometimes"@en ;
                                                                                 rdf:rest rdf:nil
                                                                               ]
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            dcterms:conformsTo UMLS:C3829094 ;
            rdfs:comment "I have been limited in my ability to do things away from home"@en ;
            rdfs:label "MFIS_Q9"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSInPaediatricAge
bto:MSInPaediatricAge rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:Patient ;
                      rdfs:range xsd:boolean ;
                      rdfs:comment "An indicator of whether the patient contracted Multiple Sclerosis (MS) in paediatric age."@en ;
                      rdfs:label "MSInPaediatricAge"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q1
bto:MSQOL54_Q1 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "Excellent"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Fair"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Good"@en ;
                                                              rdf:rest [ rdf:type rdf:List ;
                                                                         rdf:first "Very good"@en ;
                                                                         rdf:rest rdf:nil
                                                                       ]
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828889 ;
               rdfs:comment "In general, would you say your health is:"@en ;
               rdfs:label "MSQOL54_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q10
bto:MSQOL54_Q10 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "No, not limited at all"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Yes, limited a little"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Yes, limited a lot"@en ;
                                                               rdf:rest rdf:nil
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828905 ;
                rdfs:comment "Does your health limit you in walking several blocks? If so, how much?"@en ;
                rdfs:label "MSQOL54_Q10"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q11
bto:MSQOL54_Q11 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "No, not limited at all"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Yes, limited a little"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Yes, limited a lot"@en ;
                                                               rdf:rest rdf:nil
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828906 ;
                rdfs:comment "Does your health limit you in walking one block? If so, how much?"@en ;
                rdfs:label "MSQOL54_Q11"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q12
bto:MSQOL54_Q12 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "No, not limited at all"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Yes, limited a little"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Yes, limited a lot"@en ;
                                                               rdf:rest rdf:nil
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828914 ;
                rdfs:comment "Does your health limit you in bathing and dressing yourself? If so, how much?"@en ;
                rdfs:label "MSQOL54_Q12"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q13
bto:MSQOL54_Q13 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range xsd:boolean ;
                dcterms:conformsTo UMLS:C3828897 ;
                rdfs:comment "During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? Cut down on the amount of time you could spend on work or other activities"@en ;
                rdfs:label "MSQOL54_Q13"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q14
bto:MSQOL54_Q14 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range xsd:boolean ;
                dcterms:conformsTo UMLS:C3828898 ;
                rdfs:comment "During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? Accomplished less than you would like"@en ;
                rdfs:label "MSQOL54_Q14"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q15
bto:MSQOL54_Q15 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range xsd:boolean ;
                dcterms:conformsTo UMLS:C3828895 ;
                rdfs:comment "During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? Were limited in the kind of work or other activities"@en ;
                rdfs:label "MSQOL54_Q15"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q16
bto:MSQOL54_Q16 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range xsd:boolean ;
                dcterms:conformsTo UMLS:C3828895 ;
                rdfs:comment "During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? Had difficulty performing the work or other activities (for example, it took extra effor)"@en ;
                rdfs:label "MSQOL54_Q16"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q17
bto:MSQOL54_Q17 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range xsd:boolean ;
                dcterms:conformsTo UMLS:C3828931 ;
                rdfs:comment "During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious). Cut down on the amount of time you could spend on work or other activities"@en ;
                rdfs:label "MSQOL54_Q17"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q18
bto:MSQOL54_Q18 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range xsd:boolean ;
                dcterms:conformsTo UMLS:C3828932 ;
                rdfs:comment "During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious). Accomplished less than you would like"@en ;
                rdfs:label "MSQOL54_Q18"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q19
bto:MSQOL54_Q19 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range xsd:boolean ;
                dcterms:conformsTo UMLS:C3828930 ;
                rdfs:comment "During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious). Didn’t do work or other activities as carefully as usual"@en ;
                rdfs:label "MSQOL54_Q19"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q2
bto:MSQOL54_Q2 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "About the same"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Much better now than one year ago"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Much worse now than one year ago"@en ;
                                                              rdf:rest [ rdf:type rdf:List ;
                                                                         rdf:first "Somewhat better now than one year ago"@en ;
                                                                         rdf:rest [ rdf:type rdf:List ;
                                                                                    rdf:first "Somewhat worse now than one year ago"@en ;
                                                                                    rdf:rest rdf:nil
                                                                                  ]
                                                                       ]
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828904 ;
               rdfs:comment "Compared to one year ago, how would you rate your health in general now?"@en ;
               rdfs:label "MSQOL54_Q2"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q20
bto:MSQOL54_Q20 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Moderately"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Not at all"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Quite a bit"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Slightly"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828928 ;
                rdfs:comment "During the past 4 weeks, to what extent has your physical health or emotional problems interfered with your normal social activities with family, friends, neighbors, or groups?"@en ;
                rdfs:label "MSQOL54_Q20"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q21
bto:MSQOL54_Q21 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Mild"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Moderate"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "None"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Severe"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Very mild"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828938 ;
                rdfs:comment "How much bodily pain have you had during the past 4 weeks?"@en ;
                rdfs:label "MSQOL54_Q21"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q22
bto:MSQOL54_Q22 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A little bit"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Moderately"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Not at all"@en ;
                                                               rdf:rest rdf:nil
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828899 ;
                rdfs:comment "During the past 4 weeks, how much did pain interfere with your normal work (including both work outside the home and housework)?"@en ;
                rdfs:label "MSQOL54_Q22"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q23
bto:MSQOL54_Q23 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828927 ;
                rdfs:comment "How much of the time during the past 4 weeks did you feel full of pep?"@en ;
                rdfs:label "MSQOL54_Q23"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q24
bto:MSQOL54_Q24 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828939 ;
                rdfs:comment "How much of the time during the past 4 weeks have you been a very nervous person?"@en ;
                rdfs:label "MSQOL54_Q24"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q25
bto:MSQOL54_Q25 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828920 ;
                rdfs:comment "How much of the time during the past 4 weeks have you felt so down in the dumps that nothing could cheer you up?"@en ;
                rdfs:label "MSQOL54_Q25"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q26
bto:MSQOL54_Q26 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828922 ;
                rdfs:comment "How much of the time during the past 4 weeks have you felt calm and peaceful?"@en ;
                rdfs:label "MSQOL54_Q26"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q27
bto:MSQOL54_Q27 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828917 ;
                rdfs:comment "How much of the time during the past 4 weeks did you have a lot of energy?"@en ;
                rdfs:label "MSQOL54_Q27"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q28
bto:MSQOL54_Q28 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828921 ;
                rdfs:comment "How much of the time during the past 4 weeks have you felt downhearted and blue?"@en ;
                rdfs:label "MSQOL54_Q28"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q29
bto:MSQOL54_Q29 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828923 ;
                rdfs:comment "How much of the time during the past 4 weeks did you feel worn out?"@en ;
                rdfs:label "MSQOL54_Q29"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q3
bto:MSQOL54_Q3 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "No, not limited at all"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Yes, limited a little"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Yes, limited a lot"@en ;
                                                              rdf:rest rdf:nil
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828908 ;
               rdfs:comment "Does your health limit you in vigorous activities, such as running, lifting heavy objects, participating in strenuous sports? If so, how much?"@en ;
               rdfs:label "MSQOL54_Q3"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q30
bto:MSQOL54_Q30 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828940 ;
                rdfs:comment "How much of the time during the past 4 weeks have you been a happy person?"@en ;
                rdfs:label "MSQOL54_Q30"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q31
bto:MSQOL54_Q31 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828925 ;
                rdfs:comment "How much of the time during the past 4 weeks did you feel tired?"@en ;
                rdfs:label "MSQOL54_Q31"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q32
bto:MSQOL54_Q32 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828926 ;
                rdfs:comment "How much of the time during the past 4 weeks did you feel rested on waking in the morning?"@en ;
                rdfs:label "MSQOL54_Q32"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q33
bto:MSQOL54_Q33 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828892 ;
                rdfs:comment "During the past 4 weeks, how much of the time has your physical health or emotional problems interfered with your social activities (like visiting with friends, relatives, etc.)?"@en ;
                rdfs:label "MSQOL54_Q33"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q34
bto:MSQOL54_Q34 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Definitely false"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Definitely true"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Mostly false"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Mostly true"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Not sure"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828918 ;
                rdfs:comment "I seem to get sick a little easier than other people"@en ;
                rdfs:label "MSQOL54_Q34"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q35
bto:MSQOL54_Q35 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Definitely false"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Definitely true"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Mostly false"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Mostly true"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Not sure"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828941 ;
                rdfs:comment "I am as healthy as anybody I know"@en ;
                rdfs:label "MSQOL54_Q35"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q36
bto:MSQOL54_Q36 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Definitely false"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Definitely true"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Mostly false"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Mostly true"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Not sure"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828929 ;
                rdfs:comment "I expect my health to get worse"@en ;
                rdfs:label "MSQOL54_Q36"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q37
bto:MSQOL54_Q37 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Definitely false"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Definitely true"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Mostly false"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Mostly true"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Not sure"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828915 ;
                rdfs:comment "My health is excellent"@en ;
                rdfs:label "MSQOL54_Q37"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q38
bto:MSQOL54_Q38 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828933 ;
                rdfs:comment "How much of the time during the past 4 weeks were you discouraged by your health problems?"@en ;
                rdfs:label "MSQOL54_Q38"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q39
bto:MSQOL54_Q39 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828919 ;
                rdfs:comment "How much of the time during the past 4 weeks were you frustrated about your health?"@en ;
                rdfs:label "MSQOL54_Q39"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q4
bto:MSQOL54_Q4 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "No, not limited at all"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Yes, limited a little"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Yes, limited a lot"@en ;
                                                              rdf:rest rdf:nil
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828909 ;
               rdfs:comment "Does your health limit you in moderate activities, such as moving a table, pushing a vacuum cleaner, bowling, or playing golf?"@en ;
               rdfs:label "MSQOL54_Q4"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q40
bto:MSQOL54_Q40 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828916 ;
                rdfs:comment "How much of the time during the past 4 weeks was your health a worry in your life?"@en ;
                rdfs:label "MSQOL54_Q40"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q41
bto:MSQOL54_Q41 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828924 ;
                rdfs:comment "How much of the time during the past 4 weeks did you feel weighed down by your health problems?"@en ;
                rdfs:label "MSQOL54_Q41"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q42
bto:MSQOL54_Q42 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828935 ;
                rdfs:comment "How much of the time during the past 4 weeks have you had difficulty concentrating and thinking?"@en ;
                rdfs:label "MSQOL54_Q42"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q43
bto:MSQOL54_Q43 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828891 ;
                rdfs:comment "How much of the time during the past 4 weeks did you have trouble keeping your attention on an activity for long?"@en ;
                rdfs:label "MSQOL54_Q43"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q44
bto:MSQOL54_Q44 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828890 ;
                rdfs:comment "How much of the time during the past 4 weeks have you had trouble with your memory?"@en ;
                rdfs:label "MSQOL54_Q44"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q45
bto:MSQOL54_Q45 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A good bit of the time"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "A little of the time"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "All of the time"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Most of the time"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "None of the time"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Some of the time"@en ;
                                                                                                rdf:rest rdf:nil
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828901 ;
                rdfs:comment "How much of the time during the past 4 weeks have others, such as family members or friends, noticed that you have trouble with your memory or problems with your concentration?"@en ;
                rdfs:label "MSQOL54_Q45"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q46
bto:MSQOL54_Q46 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A little of a problem"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Not a problem"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Somewhat of a problem"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Very much a problem"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828902 ;
                rdfs:comment "How much of a problem was the lack of sexual interest for you during the past 4 weeks?"@en ;
                rdfs:label "MSQOL54_Q46"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q47
bto:MSQOL54_Q47 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A little of a problem"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Not a problem"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Somewhat of a problem"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Very much a problem"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3827368 ;
                rdfs:comment "How much of a problem was the difficulty getting or keeping an erection for you during the past 4 weeks?"@en ;
                rdfs:label "MSQOL54_Q47"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q48
bto:MSQOL54_Q48 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A little of a problem"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Not a problem"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Somewhat of a problem"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Very much a problem"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828934 ;
                rdfs:comment "How much of a problem was the difficulty having orgasm for you during the past 4 weeks?"@en ;
                rdfs:label "MSQOL54_Q48"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q49
bto:MSQOL54_Q49 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "A little of a problem"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Not a problem"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Somewhat of a problem"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Very much a problem"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828942 ;
                rdfs:comment "How much of a problem was the for ability to satisfy sexual partner you during the past 4 weeks?"@en ;
                rdfs:label "MSQOL54_Q49"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q5
bto:MSQOL54_Q5 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "No, not limited at all"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Yes, limited a little"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Yes, limited a lot"@en ;
                                                              rdf:rest rdf:nil
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828910 ;
               rdfs:comment "Does your health limit you in lifting or carrying groceries? If so, how much?"@en ;
               rdfs:label "MSQOL54_Q5"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q50
bto:MSQOL54_Q50 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Neither satisfied nor dissatisfied"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Somewhat dissatisfied"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Somewhat satisfied"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Very dissatisfied"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Very satisfied"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3827367 ;
                rdfs:comment "Overall, how satisfied were you with your sexual function during the past 4 weeks?"@en ;
                rdfs:label "MSQOL54_Q50"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q51
bto:MSQOL54_Q51 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Extremely"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Moderately"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Not at all"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Quite a bit"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Slightly"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828937 ;
                rdfs:comment "During the past 4 weeks, to what extent have problems with your bowel or bladder function interfered with your normal social activities with family, friends, neighbors, or groups?"@en ;
                rdfs:label "MSQOL54_Q51"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q52
bto:MSQOL54_Q52 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Extremely"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Moderately"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Not at all"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Quite a bit"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Slightly"@en ;
                                                                                     rdf:rest rdf:nil
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828900 ;
                rdfs:comment "During the past 4 weeks, how much did pain interfere with your enjoyment of life?"@en ;
                rdfs:label "MSQOL54_Q52"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q53
bto:MSQOL54_Q53 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:onDatatype xsd:float ;
                             owl:withRestrictions ( [ xsd:minInclusive "0.0"^^xsd:float
                                                    ]
                                                    [ xsd:maxInclusive "10.0"^^xsd:float
                                                    ]
                                                  )
                           ] ;
                dcterms:conformsTo UMLS:C3828893 ;
                rdfs:comment "Overall, how would you rate your own quality-of-life?"@en ;
                rdfs:label "MSQOL54_Q53"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q54
bto:MSQOL54_Q54 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:MSQOL54 ;
                rdfs:range [ rdf:type rdfs:Datatype ;
                             owl:oneOf [ rdf:type rdf:List ;
                                         rdf:first "Delighted"@en ;
                                         rdf:rest [ rdf:type rdf:List ;
                                                    rdf:first "Mixed - about equally satisfied and dissatisfied"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Mostly dissatisfied"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Mostly satisfied"@en ;
                                                                          rdf:rest [ rdf:type rdf:List ;
                                                                                     rdf:first "Pleased"@en ;
                                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                                rdf:first "Terrible"@en ;
                                                                                                rdf:rest [ rdf:type rdf:List ;
                                                                                                           rdf:first "Unhappy"@en ;
                                                                                                           rdf:rest rdf:nil
                                                                                                         ]
                                                                                              ]
                                                                                   ]
                                                                        ]
                                                             ]
                                                  ]
                                       ]
                           ] ;
                dcterms:conformsTo UMLS:C3828936 ;
                rdfs:comment "Which best describes how you feel about your life as a whole?"@en ;
                rdfs:label "MSQOL54_Q54"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q6
bto:MSQOL54_Q6 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "No, not limited at all"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Yes, limited a little"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Yes, limited a lot"@en ;
                                                              rdf:rest rdf:nil
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828911 ;
               rdfs:comment "Does your health limit you in climbing several flights of stair? If so, how much?"@en ;
               rdfs:label "MSQOL54_Q6"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q7
bto:MSQOL54_Q7 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "No, not limited at all"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Yes, limited a little"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Yes, limited a lot"@en ;
                                                              rdf:rest rdf:nil
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828912 ;
               rdfs:comment "Does your health limit you in climbing one flights of stair? If so, how much?"@en ;
               rdfs:label "MSQOL54_Q7"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q8
bto:MSQOL54_Q8 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "No, not limited at all"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Yes, limited a little"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Yes, limited a lot"@en ;
                                                              rdf:rest rdf:nil
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828913 ;
               rdfs:comment "Does your health limit you in bending, kneeling, or stooping? If so, how much?"@en ;
               rdfs:label "MSQOL54_Q8"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54_Q9
bto:MSQOL54_Q9 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:MSQOL54 ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "No, not limited at all"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Yes, limited a little"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Yes, limited a lot"@en ;
                                                              rdf:rest rdf:nil
                                                            ]
                                                 ]
                                      ]
                          ] ;
               dcterms:conformsTo UMLS:C3828907 ;
               rdfs:comment "Does your health limit you in walking more than a mile? If so, how much?"@en ;
               rdfs:label "MSQOL54_Q9"@en .


###  https://w3id.org/brainteaser/ontology/schema/PFTs_FEV1_L
bto:PFTs_FEV1_L rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:PFTs ;
                rdfs:range xsd:float ;
                dcterms:conformsTo UMLS:C0849974 ;
                rdfs:comment "A test of lung function, the FEV1 is the volume exhaled during the first second of a forced expiratory maneuver started from the level of total lung capacity. It is the most frequently used index for assessing bronchoconstriction or bronchodilatation. [Definition Source: NCI]"@en ;
                rdfs:label "PFTs_FEV1_L"@en .


###  https://w3id.org/brainteaser/ontology/schema/PFTs_FEV1_P
bto:PFTs_FEV1_P rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:PFTs ;
                rdfs:range xsd:float ;
                dcterms:conformsTo UMLS:C0849974 ;
                rdfs:comment "A test of lung function, the FEV1 is the volume exhaled during the first second of a forced expiratory maneuver started from the level of total lung capacity. It is the most frequently used index for assessing bronchoconstriction or bronchodilatation. [Definition Source: NCI]"@en ;
                rdfs:label "PFTs_FEV1_P"@en .


###  https://w3id.org/brainteaser/ontology/schema/PFTs_FEV6_L
bto:PFTs_FEV6_L rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:PFTs ;
                rdfs:range xsd:float ;
                dcterms:conformsTo UMLS:C1708092 ;
                rdfs:comment "A test of lung function, the FEV6 is the volume exhaled during six seconds of a forced expiratory maneuver started from the level of total lung capacity. [Definition Source: NCI]"@en ;
                rdfs:label "PFTs_FEV6_L"@en .


###  https://w3id.org/brainteaser/ontology/schema/PFTs_FEV6_P
bto:PFTs_FEV6_P rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:PFTs ;
                rdfs:range xsd:float ;
                dcterms:conformsTo UMLS:C1708092 ;
                rdfs:comment "A test of lung function, the FEV6 is the volume exhaled during six seconds of a forced expiratory maneuver started from the level of total lung capacity. [Definition Source: NCI]"@en ;
                rdfs:label "PFTs_FEV6_P"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q1
bto:PSQI_Q1 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:PSQI ;
            rdfs:range xsd:time ;
            rdfs:comment "During the past month, what time have you usually gone to bed at night?"@en ;
            rdfs:label "PSQI_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q10
bto:PSQI_Q10 rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "No bed partner or room mate"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Partner in same bed"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Partner/room mate in other room"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Partner/room mate in same room but not same bed"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Do you have a bed partner or room mate?"@en ;
             rdfs:label "PSQI_Q10"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q11A
bto:PSQI_Q11A rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:PSQI ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "Less than once a week"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "Not during the past month"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "Once or twice a week"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "Three or more times a week"@en ;
                                                                        rdf:rest rdf:nil
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Loud snoring"@en ;
              rdfs:label "PSQI_Q11A"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q11B
bto:PSQI_Q11B rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:PSQI ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "Less than once a week"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "Not during the past month"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "Once or twice a week"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "Three or more times a week"@en ;
                                                                        rdf:rest rdf:nil
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Long pauses between breaths while asleep"@en ;
              rdfs:label "PSQI_Q11B"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q11C
bto:PSQI_Q11C rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:PSQI ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "Less than once a week"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "Not during the past month"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "Once or twice a week"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "Three or more times a week"@en ;
                                                                        rdf:rest rdf:nil
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Legs twitching or jerking while you sleep"@en ;
              rdfs:label "PSQI_Q11C"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q11D
bto:PSQI_Q11D rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:PSQI ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "Less than once a week"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "Not during the past month"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "Once or twice a week"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "Three or more times a week"@en ;
                                                                        rdf:rest rdf:nil
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Episodes of disorientation or confusion during sleep"@en ;
              rdfs:label "PSQI_Q11D"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q11E
bto:PSQI_Q11E rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:PSQI ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "Less than once a week"@en ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "Not during the past month"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "Once or twice a week"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "Three or more times a week"@en ;
                                                                        rdf:rest rdf:nil
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "Other restlessness while you sleep, please describe"@en ;
              rdfs:label "PSQI_Q11E"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q2
bto:PSQI_Q2 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:PSQI ;
            rdfs:range xsd:int ;
            rdfs:comment "During the past month, how long (in minutes) has it usually taken you to fall asleep each night?"@en ;
            rdfs:label "PSQI_Q2"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q3
bto:PSQI_Q3 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:PSQI ;
            rdfs:range xsd:time ;
            rdfs:comment "During the past month, what time have you usually gotten up in the morning?"@en ;
            rdfs:label "PSQI_Q3"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q4
bto:PSQI_Q4 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:PSQI ;
            rdfs:range xsd:int ;
            rdfs:comment "During the past month, how many hours of actual sleep did you get at night? (This may be different than the number of hours you spent in bed.)"@en ;
            rdfs:label "PSQI_Q4"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5A
bto:PSQI_Q5A rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Cannot get to sleep within 30 minutes"@en ;
             rdfs:label "PSQI_Q5A"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5B
bto:PSQI_Q5B rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Wake up in the middle of the night or early morning"@en ;
             rdfs:label "PSQI_Q5B"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5C
bto:PSQI_Q5C rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Have to get up to use the bathroom"@en ;
             rdfs:label "PSQI_Q5C"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5D
bto:PSQI_Q5D rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Cannot breathe comfortably"@en ;
             rdfs:label "PSQI_Q5D"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5E
bto:PSQI_Q5E rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Cough or snore loudly"@en ;
             rdfs:label "PSQI_Q5E"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5F
bto:PSQI_Q5F rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Feel too cold"@en ;
             rdfs:label "PSQI_Q5F"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5G
bto:PSQI_Q5G rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Feel too hot"@en ;
             rdfs:label "PSQI_Q5G"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5H
bto:PSQI_Q5H rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Have bad dreams"@en ;
             rdfs:label "PSQI_Q5H"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5I
bto:PSQI_Q5I rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:PSQI ;
             rdfs:range [ rdf:type rdfs:Datatype ;
                          owl:oneOf [ rdf:type rdf:List ;
                                      rdf:first "Less than once a week"@en ;
                                      rdf:rest [ rdf:type rdf:List ;
                                                 rdf:first "Not during the past month"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "Once or twice a week"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Three or more times a week"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                    ]
                        ] ;
             rdfs:comment "Have pain"@en ;
             rdfs:label "PSQI_Q5I"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5J_1
bto:PSQI_Q5J_1 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:PSQI ;
               rdfs:range rdf:PlainLiteral ;
               rdfs:comment "Other reason(s), please describe:"@en ;
               rdfs:label "PSQI_Q5J_1"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q5J_2
bto:PSQI_Q5J_2 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:PSQI ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:oneOf [ rdf:type rdf:List ;
                                        rdf:first "Less than once a week"@en ;
                                        rdf:rest [ rdf:type rdf:List ;
                                                   rdf:first "Not during the past month"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Once or twice a week"@en ;
                                                              rdf:rest [ rdf:type rdf:List ;
                                                                         rdf:first "Three or more times a week"@en ;
                                                                         rdf:rest rdf:nil
                                                                       ]
                                                            ]
                                                 ]
                                      ]
                          ] ;
               rdfs:comment "how often have you had trouble sleeping because of this?"@en ;
               rdfs:label "PSQI_Q5J_2"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q6
bto:PSQI_Q6 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:PSQI ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Less than once a week"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Not during the past month"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Once or twice a week"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Three or more times a week"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            rdfs:comment "During the past month, how often have you taken medicine to help you sleep (prescribed or “over the counter”)?"@en ;
            rdfs:label "PSQI_Q6"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q7
bto:PSQI_Q7 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:PSQI ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Less than once a week"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Not during the past month"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Once or twice a week"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Three or more times a week"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            rdfs:comment "During the past month, how often have you had trouble staying awake while driving, eating meals, or engaging in social activity?"@en ;
            rdfs:label "PSQI_Q7"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q8
bto:PSQI_Q8 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:PSQI ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "A very big problem"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "No problem at all"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Only a very slight problem"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Somewhat of a problem"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            rdfs:comment "During the past month, how much of a problem has it been for you to keep up enough enthusiasm to get things done?"@en ;
            rdfs:label "PSQI_Q8"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI_Q9
bto:PSQI_Q9 rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:PSQI ;
            rdfs:range [ rdf:type rdfs:Datatype ;
                         owl:oneOf [ rdf:type rdf:List ;
                                     rdf:first "Fairly bad"@en ;
                                     rdf:rest [ rdf:type rdf:List ;
                                                rdf:first "Fairly good"@en ;
                                                rdf:rest [ rdf:type rdf:List ;
                                                           rdf:first "Very bad"@en ;
                                                           rdf:rest [ rdf:type rdf:List ;
                                                                      rdf:first "Very good"@en ;
                                                                      rdf:rest rdf:nil
                                                                    ]
                                                         ]
                                              ]
                                   ]
                       ] ;
            rdfs:comment "During the past month, how would you rate your sleep quality overall?"@en ;
            rdfs:label "PSQI_Q9"@en .


###  https://w3id.org/brainteaser/ontology/schema/SLEEP_ALS_Q1
bto:SLEEP_ALS_Q1 rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:SLEEP_ALS ;
                 rdfs:range [ rdf:type rdfs:Datatype ;
                              owl:onDatatype xsd:float ;
                              owl:withRestrictions ( [ xsd:minInclusive "0.0"^^xsd:float
                                                     ]
                                                     [ xsd:maxInclusive "10.0"^^xsd:float
                                                     ]
                                                   )
                            ] ;
                 dcterms:conformsTo UMLS:C4054285 ;
                 rdfs:comment "During the last 7 days, how would you rate your sleep quality overall? Choose a number from 1 to 10 that best describes your sleep quality"@en ;
                 rdfs:label "SLEEP_ALS_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/VASQ1
bto:VASQ1 rdf:type owl:DatatypeProperty ;
          rdfs:domain bto:VAS ;
          rdfs:range [ rdf:type rdfs:Datatype ;
                       owl:onDatatype xsd:float ;
                       owl:withRestrictions ( [ xsd:minInclusive "0.0"^^xsd:float
                                              ]
                                              [ xsd:maxInclusive "10.0"^^xsd:float
                                              ]
                                            )
                     ] ;
          dcterms:conformsTo UMLS:C0042815 ;
          rdfs:comment "Choose a number from 0 to 10 that best describes your pain"@en ;
          rdfs:label "VAS_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/WEIGHT_Q1
bto:WEIGHT_Q1 rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:WEIGHT ;
              rdfs:range xsd:float ;
              rdfs:comment "Please, enter your weight"@en ;
              rdfs:label "WEIGHT_Q1"@en .


###  https://w3id.org/brainteaser/ontology/schema/abdominalSurgery
bto:abdominalSurgery rdf:type owl:DatatypeProperty ;
                     rdfs:domain [ rdf:type owl:Class ;
                                   owl:unionOf ( bto:Last5YearsEvent
                                                 bto:MoreThan5YearsEvent
                                               )
                                 ] ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether a patient had an abdominal surgery."@en ;
                     rdfs:label "abdominalSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/activeKilocalories
bto:activeKilocalories rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:PhysicalActivityData ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Active kilocalories registered by the wearable device. [uom: kcal]"@en ;
                       rdfs:label "activeKilocalories"@en .


###  https://w3id.org/brainteaser/ontology/schema/activeTime
bto:activeTime rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:PhysicalActivityData ;
               rdfs:range xsd:float ;
               rdfs:comment "Active time registered by the wearable device. [uom: seconds]"@en ;
               rdfs:label "activeTime"@en .


###  https://w3id.org/brainteaser/ontology/schema/activityDistance
bto:activityDistance rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:PhysicalActivityData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "Activity distance registered by the wearable device. [uom: meters]"@en ;
                     rdfs:label "activityDistance"@en .


###  https://w3id.org/brainteaser/ontology/schema/activityEndYear
bto:activityEndYear rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:Activity ;
                    rdfs:range xsd:gYear ;
                    rdfs:comment "The year in which an activity ended."@en ;
                    rdfs:label "activityEndYear"@en .


###  https://w3id.org/brainteaser/ontology/schema/activityIntensity
bto:activityIntensity rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:PhysicalActivity ;
                      rdfs:range [ rdf:type rdfs:Datatype ;
                                   owl:oneOf [ rdf:type rdf:List ;
                                               rdf:first "Intense"@en ;
                                               rdf:rest [ rdf:type rdf:List ;
                                                          rdf:first "Moderate"@en ;
                                                          rdf:rest [ rdf:type rdf:List ;
                                                                     rdf:first "Professional"@en ;
                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                rdf:first "Soft"@en ;
                                                                                rdf:rest rdf:nil
                                                                              ]
                                                                   ]
                                                        ]
                                             ]
                                 ] ;
                      rdfs:comment "The level of intensity with which the physical activity is carried out."@en ;
                      rdfs:label "activityIntensity"@en .


###  https://w3id.org/brainteaser/ontology/schema/activityStartYear
bto:activityStartYear rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:Activity ;
                      rdfs:range xsd:gYear ;
                      rdfs:comment "The year in which the activity started."@en ;
                      rdfs:label "activityStartYear"@en .


###  https://w3id.org/brainteaser/ontology/schema/activitySteps
bto:activitySteps rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:PhysicalActivityData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Activity steps registered by the wearable device."@en ;
                  rdfs:label "activitySteps"@en .


###  https://w3id.org/brainteaser/ontology/schema/activityStepsGoal
bto:activityStepsGoal rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:PhysicalActivityData ;
                      rdfs:range xsd:float ;
                      rdfs:comment "Activity steps goal registered by the wearable device."@en ;
                      rdfs:label "activityStepsGoal"@en .


###  https://w3id.org/brainteaser/ontology/schema/activityStressDuration
bto:activityStressDuration rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:StressLevel ;
                           rdfs:range xsd:float ;
                           rdfs:comment "Activity stress duration registered by the wearable device. [uom: seconds]"@en ;
                           rdfs:label "activityStressDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/activityType
bto:activityType rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:PhysicalActivity ;
                 rdfs:range rdf:PlainLiteral ;
                 rdfs:comment "The type of physical activity carried out."@en ;
                 rdfs:label "activityType"@en .


###  https://w3id.org/brainteaser/ontology/schema/administrationFrequency
bto:administrationFrequency rdf:type owl:DatatypeProperty ,
                                     owl:FunctionalProperty ;
                            rdfs:domain bto:Administration ;
                            rdfs:range rdf:PlainLiteral ;
                            rdfs:comment "The frequency of administration of the pharmacological substance."@en ;
                            rdfs:label "administrationFrequency"@en .


###  https://w3id.org/brainteaser/ontology/schema/administrationRoute
bto:administrationRoute rdf:type owl:DatatypeProperty ,
                                 owl:FunctionalProperty ;
                        rdfs:domain bto:Administration ;
                        rdfs:range rdf:PlainLiteral ;
                        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0013153"@en ;
                        rdfs:comment "Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. [Definition Source: NCI][attribution: ICH]"@en ;
                        rdfs:label "administrationRoute"@en .


###  https://w3id.org/brainteaser/ontology/schema/administrationUoM
bto:administrationUoM rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:Administration ;
                      rdfs:range rdf:PlainLiteral ;
                      rdfs:comment "The Unit of Measure (UoM) of the adminstration dose."@en ;
                      rdfs:label "administrationUoM"@en .


###  https://w3id.org/brainteaser/ontology/schema/adminstrationDose
bto:adminstrationDose rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:Administration ;
                      rdfs:range xsd:float ;
                      rdfs:comment "A definite quantity of a medicine or drug given or prescribed to be given at one time. [Definition Source: Oxford English Dictionary]"@en ;
                      rdfs:label "administrationDose"@en .


###  https://w3id.org/brainteaser/ontology/schema/ageBaseline
bto:ageBaseline rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:Patient ;
                rdfs:range xsd:float ;
                rdfs:comment "The MS patient's age at baseline. Expressed in years."@en ;
                rdfs:label "ageBaseline"@en .


###  https://w3id.org/brainteaser/ontology/schema/ageDiagnosis
bto:ageDiagnosis rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:Diagnosis ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Age of the patient at the diagnosis."@en ;
                 rdfs:label "ageDiagnosis"@en .


###  https://w3id.org/brainteaser/ontology/schema/ageOnset
bto:ageOnset rdf:type owl:DatatypeProperty ,
                      owl:FunctionalProperty ;
             rdfs:domain bto:Onset ;
             rdfs:range xsd:float ;
             rdfs:comment "Age of the patient at the onset."@en ;
             rdfs:label "ageOnset"@en .


###  https://w3id.org/brainteaser/ontology/schema/albuminCSF
bto:albuminCSF rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:CSFAnalysis ;
               rdfs:range xsd:float ;
               rdfs:comment "A quantitative measurement of albumin present in a sample of CSF. Unit of measure : [mg/l]."@en ;
               rdfs:label "albuminCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/alcoholUse
bto:alcoholUse rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:Lifestyle ;
               rdfs:range xsd:boolean ;
               rdfs:comment "Whether a patient drinks alcohol."@en ;
               rdfs:label "alcoholUse"@en .


###  https://w3id.org/brainteaser/ontology/schema/alive
bto:alive rdf:type owl:DatatypeProperty ,
                   owl:FunctionalProperty ;
          rdfs:domain bto:Patient ;
          rdfs:range xsd:boolean ;
          rdfs:comment "Whether the patient is still alive."@en ;
          rdfs:label "alive"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs1
bto:alsfrs1 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 1 for ALSFRS: Speech."@en ;
            rdfs:label "alsfrs1"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs10
bto:alsfrs10 rdf:type owl:DatatypeProperty ,
                      owl:FunctionalProperty ;
             rdfs:domain bto:ALSFRS ;
             rdfs:range xsd:integer ;
             rdfs:comment "Item 10 for Revised ALSFRS: Dyspnea."@en ;
             rdfs:label "alsfrs10"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs11
bto:alsfrs11 rdf:type owl:DatatypeProperty ,
                      owl:FunctionalProperty ;
             rdfs:domain bto:ALSFRS ;
             rdfs:range xsd:integer ;
             rdfs:comment "Item 11 for Revised ALSFRS: Orthopnea."@en ;
             rdfs:label "alsfrs11"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs12
bto:alsfrs12 rdf:type owl:DatatypeProperty ,
                      owl:FunctionalProperty ;
             rdfs:domain bto:ALSFRS ;
             rdfs:range xsd:integer ;
             rdfs:comment "Item 12 for Revised ALSFRS: Respiratory Insufficiency."@en ;
             rdfs:label "alsfrs12"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs2
bto:alsfrs2 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 2 for ALSFRS: Salivation."@en ;
            rdfs:label "alsfrs2"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs3
bto:alsfrs3 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 3 for ALSFRS: Swallowing."@en ;
            rdfs:label "alsfrs3"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs4
bto:alsfrs4 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 4 for ALSFRS: Handwriting."@en ;
            rdfs:label "alsfrs4"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs5
bto:alsfrs5 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 5 for ALSFRS: Cutting food and handling utensilis."@en ;
            rdfs:label "alsfrs5"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs6
bto:alsfrs6 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 6 for ALSFRS: Dressing and hygiene."@en ;
            rdfs:label "alsfrs6"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs7
bto:alsfrs7 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 7 for ALSFRS: Turning in bed and adjusting blankets."@en ;
            rdfs:label "alsfrs7"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs8
bto:alsfrs8 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 8 for ALSFRS: Walking."@en ;
            rdfs:label "alsfrs8"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrs9
bto:alsfrs9 rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:ALSFRS ;
            rdfs:range xsd:integer ;
            rdfs:comment "Item 9 for ALSFRS: Climbing Stairs."@en ;
            rdfs:label "alsfrs9"@en .


###  https://w3id.org/brainteaser/ontology/schema/alsfrsOriginal10
bto:alsfrsOriginal10 rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:ALSFRS ;
                     rdfs:range xsd:integer ;
                     rdfs:comment "Original item 10 for ALSFRS: Breathing."@en ;
                     rdfs:label "alsfrsOriginal10"@en .


###  https://w3id.org/brainteaser/ontology/schema/alterationCSF
bto:alterationCSF rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:CSFAnalysis ;
                  rdfs:range [ rdf:type rdfs:Datatype ;
                               owl:oneOf [ rdf:type rdf:List ;
                                           rdf:first "atypical alteration for MS" ;
                                           rdf:rest [ rdf:type rdf:List ;
                                                      rdf:first "normal" ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "traumatic" ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "typical alteration for MS" ;
                                                                            rdf:rest rdf:nil
                                                                          ]
                                                               ]
                                                    ]
                                         ]
                             ] ;
                  rdfs:comment "Whether the CSF specimen is normal or presents alterations."@en ;
                  rdfs:label "alterationCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/ambulationEDSS
bto:ambulationEDSS rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:EDSS ;
                   rdfs:range xsd:integer ;
                   rdfs:comment "Expanded Disability Status Score (EDSS) score for ambulation."@en ;
                   rdfs:label "ambulationEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/ambulationEDSSAssistance
bto:ambulationEDSSAssistance rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:EDSS ;
                             rdfs:range xsd:boolean ;
                             rdfs:comment "Whether the patient used assistance to perform the ambulation test."@en ;
                             rdfs:label "ambulationEDSSAssistance"@en .


###  https://w3id.org/brainteaser/ontology/schema/ambulationEDSSObservedTime
bto:ambulationEDSSObservedTime rdf:type owl:DatatypeProperty ;
                               rdfs:domain bto:EDSS ;
                               rdfs:range xsd:float ;
                               rdfs:comment "Observed time to walk 500m (in minutes)"@en ;
                               rdfs:label "ambulationEDSSObservedTime"@en .


###  https://w3id.org/brainteaser/ontology/schema/ambulationEDSSPatientDistance
bto:ambulationEDSSPatientDistance rdf:type owl:DatatypeProperty ;
                                  rdfs:domain bto:EDSS ;
                                  rdfs:range xsd:integer ;
                                  rdfs:comment "Distance reported by patient (in meters) without stopping"@en ;
                                  rdfs:label "ambulationEDSSPatientDistance"@en .


###  https://w3id.org/brainteaser/ontology/schema/ambulationEDSSPatientTime
bto:ambulationEDSSPatientTime rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:EDSS ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "Time reported by patient (in minutes) without stopping"@en ;
                              rdfs:label "ambulationEDSSPatientTime"@en .


###  https://w3id.org/brainteaser/ontology/schema/ankleFootOrthosis
bto:ankleFootOrthosis rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:WalkTest ;
                      rdfs:range xsd:boolean ;
                      rdfs:comment "Whether the patient has ankle/foot orthosis."@en ;
                      rdfs:label "ankleFootOrthosis"@en .


###  https://w3id.org/brainteaser/ontology/schema/ashworthLeftArm
bto:ashworthLeftArm rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:MuscleToneAssessment ;
                    rdfs:range [ rdf:type rdfs:Datatype ;
                                 owl:onDatatype xsd:integer ;
                                 owl:withRestrictions ( [ xsd:minInclusive 0
                                                        ]
                                                        [ xsd:maxInclusive 4
                                                        ]
                                                      )
                               ] ;
                    rdfs:comment "Muscle tone assessment of the left arm."@en ;
                    rdfs:label "ashworthLeftArm"@en .


###  https://w3id.org/brainteaser/ontology/schema/ashworthLeftLeg
bto:ashworthLeftLeg rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:MuscleToneAssessment ;
                    rdfs:range [ rdf:type rdfs:Datatype ;
                                 owl:onDatatype xsd:integer ;
                                 owl:withRestrictions ( [ xsd:minInclusive 0
                                                        ]
                                                        [ xsd:maxInclusive 4
                                                        ]
                                                      )
                               ] ;
                    rdfs:comment "Muscle tone assessment of the left leg."@en ;
                    rdfs:label "ashworthLeftLeg"@en .


###  https://w3id.org/brainteaser/ontology/schema/ashworthRightArm
bto:ashworthRightArm rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:MuscleToneAssessment ;
                     rdfs:range [ rdf:type rdfs:Datatype ;
                                  owl:onDatatype xsd:integer ;
                                  owl:withRestrictions ( [ xsd:minInclusive 0
                                                         ]
                                                         [ xsd:maxInclusive 4
                                                         ]
                                                       )
                                ] ;
                     rdfs:comment "Muscle tone assessment of the right arm."@en ;
                     rdfs:label "ashworthRightArm"@en .


###  https://w3id.org/brainteaser/ontology/schema/ashworthRightLeg
bto:ashworthRightLeg rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:MuscleToneAssessment ;
                     rdfs:range [ rdf:type rdfs:Datatype ;
                                  owl:onDatatype xsd:integer ;
                                  owl:withRestrictions ( [ xsd:minInclusive 0
                                                         ]
                                                         [ xsd:maxInclusive 4
                                                         ]
                                                       )
                                ] ;
                     rdfs:comment "Muscle tone assessment of the right leg."@en ;
                     rdfs:label "ashworthRightLeg"@en .


###  https://w3id.org/brainteaser/ontology/schema/autoimmuneDisease
bto:autoimmuneDisease rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:ALSBrainteaserComorbidities ;
                      rdfs:range xsd:boolean ;
                      rdfs:comment "Whether a patient ever had an autoimmune disease."@en ;
                      rdfs:label "autoimmuneDisease"@en .


###  https://w3id.org/brainteaser/ontology/schema/averageHeartRate
bto:averageHeartRate rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:HeartRateMeasurement ;
                     rdfs:range xsd:float ;
                     rdfs:comment "Average heart rate registered by the wearable device. [uom: bpm]"@en ;
                     rdfs:label "averageHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/averageMeasurement
bto:averageMeasurement rdf:type owl:DatatypeProperty ;
                       rdfs:domain [ rdf:type owl:Class ;
                                     owl:unionOf ( <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration>
                                                   bto:WeatherData
                                                 )
                                   ] ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Average of valid measurements in that week; if there are no valid measurements in that week, it is denoted as NA."@en ;
                       rdfs:label "averageMeasurement"@en .


###  https://w3id.org/brainteaser/ontology/schema/averageStressLevel
bto:averageStressLevel rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:StressLevel ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Average stress level registered by the wearable device."@en ;
                       rdfs:label "averageStressLevel"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiClinicalLMNBulbar
bto:awajiClinicalLMNBulbar rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:AwajiClinicalEvaluation ;
                           rdfs:range [ rdf:type rdfs:Datatype ;
                                        owl:oneOf [ rdf:type rdf:List ;
                                                    rdf:first "ND"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "No"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Yes"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                      ] ;
                           rdfs:comment "Whether the patient presents clinical Lower Motor Neuron (LMN) signs in the Bulbar region."@en ;
                           rdfs:label "awajiClinicalLMNBulbar"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiClinicalLMNCervical
bto:awajiClinicalLMNCervical rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:AwajiClinicalEvaluation ;
                             rdfs:range [ rdf:type rdfs:Datatype ;
                                          owl:oneOf [ rdf:type rdf:List ;
                                                      rdf:first "ND"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "No"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "Yes"@en ;
                                                                            rdf:rest rdf:nil
                                                                          ]
                                                               ]
                                                    ]
                                        ] ;
                             rdfs:comment "Whether the patient presents clinical Lower Motor Neuron (LMN) signs in the Cervical region."@en ;
                             rdfs:label "awajiClinicalLMNCervical"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiClinicalLMNLumboSacral
bto:awajiClinicalLMNLumboSacral rdf:type owl:DatatypeProperty ;
                                rdfs:domain bto:AwajiClinicalEvaluation ;
                                rdfs:range [ rdf:type rdfs:Datatype ;
                                             owl:oneOf [ rdf:type rdf:List ;
                                                         rdf:first "ND"@en ;
                                                         rdf:rest [ rdf:type rdf:List ;
                                                                    rdf:first "No"@en ;
                                                                    rdf:rest [ rdf:type rdf:List ;
                                                                               rdf:first "Yes"@en ;
                                                                               rdf:rest rdf:nil
                                                                             ]
                                                                  ]
                                                       ]
                                           ] ;
                                rdfs:comment "Whether the patient presents clinical Lower Motor Neuron (LMN) signs in the Lumbo-Sacral region."@en ;
                                rdfs:label "awajiClinicalLMNLumboSacral"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiClinicalLMNThoracic
bto:awajiClinicalLMNThoracic rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:AwajiClinicalEvaluation ;
                             rdfs:range [ rdf:type rdfs:Datatype ;
                                          owl:oneOf [ rdf:type rdf:List ;
                                                      rdf:first "ND"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "No"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "Yes"@en ;
                                                                            rdf:rest rdf:nil
                                                                          ]
                                                               ]
                                                    ]
                                        ] ;
                             rdfs:comment "Whether the patient presents clinical Lower Motor Neuron (LMN) signs in the Thoracic region."@en ;
                             rdfs:label "awajiClinicalLMNThoracic"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiClinicalUMNBulbar
bto:awajiClinicalUMNBulbar rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:AwajiClinicalEvaluation ;
                           rdfs:range [ rdf:type rdfs:Datatype ;
                                        owl:oneOf [ rdf:type rdf:List ;
                                                    rdf:first "ND"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "No"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Yes"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                      ] ;
                           rdfs:comment "Whether the patient presents clinical Upper Motor Neuron (UMN) signs in the Bulbar region."@en ;
                           rdfs:label "awajiClinicalUMNBulbar"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiClinicalUMNCervical
bto:awajiClinicalUMNCervical rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:AwajiClinicalEvaluation ;
                             rdfs:range [ rdf:type rdfs:Datatype ;
                                          owl:oneOf [ rdf:type rdf:List ;
                                                      rdf:first "ND"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "No"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "Yes"@en ;
                                                                            rdf:rest rdf:nil
                                                                          ]
                                                               ]
                                                    ]
                                        ] ;
                             rdfs:comment "Whether the patient presents clinical Upper Motor Neuron (UMN) signs in the Cervical region."@en ;
                             rdfs:label "awajiClinicalUMNCervical"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiClinicalUMNLumboSacral
bto:awajiClinicalUMNLumboSacral rdf:type owl:DatatypeProperty ;
                                rdfs:domain bto:AwajiClinicalEvaluation ;
                                rdfs:range [ rdf:type rdfs:Datatype ;
                                             owl:oneOf [ rdf:type rdf:List ;
                                                         rdf:first "ND"@en ;
                                                         rdf:rest [ rdf:type rdf:List ;
                                                                    rdf:first "No"@en ;
                                                                    rdf:rest [ rdf:type rdf:List ;
                                                                               rdf:first "Yes"@en ;
                                                                               rdf:rest rdf:nil
                                                                             ]
                                                                  ]
                                                       ]
                                           ] ;
                                rdfs:comment "Whether the patient presents clinical Upper Motor Neuron (UMN) signs in the Lumbo-Sacral region."@en ;
                                rdfs:label "awajiClinicalUMNLumboSacral"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiDiagnosisCriteria
bto:awajiDiagnosisCriteria rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:AwajiClinicalEvaluation ;
                           rdfs:range [ rdf:type rdfs:Datatype ;
                                        owl:oneOf [ rdf:type rdf:List ;
                                                    rdf:first "Definite"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "Possible"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Probable"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                      ] ;
                           rdfs:comment "ALS diagnosis according to the Awaji criteria."@en ;
                           rdfs:label "awajiDiagnosisCriteria"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiEMGLMNBulbar
bto:awajiEMGLMNBulbar rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:AwajiClinicalEvaluation ;
                      rdfs:range [ rdf:type rdfs:Datatype ;
                                   owl:oneOf [ rdf:type rdf:List ;
                                               rdf:first "ND"@en ;
                                               rdf:rest [ rdf:type rdf:List ;
                                                          rdf:first "No"@en ;
                                                          rdf:rest [ rdf:type rdf:List ;
                                                                     rdf:first "Yes"@en ;
                                                                     rdf:rest rdf:nil
                                                                   ]
                                                        ]
                                             ]
                                 ] ;
                      rdfs:comment "Whether the patient presents Lower Motor Neuron (LMN) signs in the Bulbar region, using needle electromyography (EMG)."@en ;
                      rdfs:label "awajiEMGLMNBulbar"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiEMGLMNCervical
bto:awajiEMGLMNCervical rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:AwajiClinicalEvaluation ;
                        rdfs:range [ rdf:type rdfs:Datatype ;
                                     owl:oneOf [ rdf:type rdf:List ;
                                                 rdf:first "ND"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "No"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Yes"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                   ] ;
                        rdfs:comment "Whether the patient presents Lower Motor Neuron (LMN) signs in the Cervical region, using needle electromyography (EMG)."@en ;
                        rdfs:label "awajiEMGLMNCervical"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiEMGLMNLumboSacral
bto:awajiEMGLMNLumboSacral rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:AwajiClinicalEvaluation ;
                           rdfs:range [ rdf:type rdfs:Datatype ;
                                        owl:oneOf [ rdf:type rdf:List ;
                                                    rdf:first "ND"@en ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "No"@en ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "Yes"@en ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                      ] ;
                           rdfs:comment "Whether the patient presents Lower Motor Neuron (LMN) signs in the Lumbo-Sacral region, using needle electromyography (EMG)."@en ;
                           rdfs:label "awajiEMGLMNLumboSacral"@en .


###  https://w3id.org/brainteaser/ontology/schema/awajiEMGLMNThoracic
bto:awajiEMGLMNThoracic rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:AwajiClinicalEvaluation ;
                        rdfs:range [ rdf:type rdfs:Datatype ;
                                     owl:oneOf [ rdf:type rdf:List ;
                                                 rdf:first "ND"@en ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "No"@en ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "Yes"@en ;
                                                                       rdf:rest rdf:nil
                                                                     ]
                                                          ]
                                               ]
                                   ] ;
                        rdfs:comment "Whether the patient presents Lower Motor Neuron (LMN) signs in the Thoracic region, using needle electromyography (EMG)."@en ;
                        rdfs:label "awajiEMGLMNThoracic"@en .


###  https://w3id.org/brainteaser/ontology/schema/awakeDuration
bto:awakeDuration rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SleepData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Awake duration registered by the wearable device. [uom: seconds]"@en ;
                  rdfs:label "awakeDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/axialOnset
bto:axialOnset rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:Onset ;
               rdfs:range xsd:boolean ;
               rdfs:comment "Whether the patient experienced axial onset. The Axial Skeleton is the part of the skeleton that includes the skull and spinal column and sternum and ribs. [Definition Source: NCI]"@en ;
               rdfs:label "axialOnset"@en .


###  https://w3id.org/brainteaser/ontology/schema/basalKilocalories
bto:basalKilocalories rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:PhysicalActivityData ;
                      rdfs:range xsd:float ;
                      rdfs:comment "Total basal calories registered by the wearable device. [uom: kcal]"@en ;
                      rdfs:label "basalKilocalories"@en .


###  https://w3id.org/brainteaser/ontology/schema/baselineHeartRate
bto:baselineHeartRate rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:HeartRateMeasurement ;
                      rdfs:range xsd:float ;
                      rdfs:comment "The baseline heart rate (at stimulus onset)."@en ;
                      rdfs:label "baselineHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatAI
bto:beatToBeatAI rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:BeatToBeatData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Area Index, defined as the cumulative area of the sectors corresponding to the points that are located above Line of Identity (LI) divided by the cumulative area of sectors corresponding to all points in the Poincaré plot except those that are located on LI."@en ;
                 rdfs:label "beatToBeatAI"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatC2a
bto:beatToBeatC2a rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "The contributions of heart rate acceleration in long-term Heart Rate Variability (HRV) (Piskorski, 2011)."@en ;
                  rdfs:label "beatToBeatC2a"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatC2d
bto:beatToBeatC2d rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "The contributions of heart rate deceleration in long-term HRV (Piskorski, 2011)."@en ;
                  rdfs:label "beatToBeatC2d"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatCSI
bto:beatToBeatCSI rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "The Cardiac Sympathetic Index (Toichi, 1997), calculated by dividing the longitudinal variability of the Poincaré plot by its transverse variability."@en ;
                  rdfs:label "beatToBeatCSI"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatCSIModified
bto:beatToBeatCSIModified rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:BeatToBeatData ;
                          rdfs:range xsd:float ;
                          rdfs:comment "The modified CSI (Jeppesen, 2014) obtained by dividing the square of the longitudinal variability by its transverse variability. "@en ;
                          rdfs:label "beatToBeatCSIModified"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatCVI
bto:beatToBeatCVI rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "The Cardiac Sympathetic Index (Toichi, 1997), equal to the logarithm of the product of longitudinal variability of the Poincaré plot by its transverse variability."@en ;
                  rdfs:label "beatToBeatCVI"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatCVSD
bto:beatToBeatCVSD rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:BeatToBeatData ;
                   rdfs:range xsd:float ;
                   rdfs:comment "The root mean square of the sum of successive differences (RMSSD) divided by the mean of the RR intervals (MeanNN)."@en ;
                   rdfs:label "beatToBeatCVSD"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatCa
bto:beatToBeatCa rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:BeatToBeatData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "The total contributions of heart rate accelerations to HRV."@en ;
                 rdfs:label "beatToBeatCa"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatCd
bto:beatToBeatCd rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:BeatToBeatData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "The total contributions of heart rate accelerations to HRV."@en ;
                 rdfs:label "beatToBeatCd"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatGI
bto:beatToBeatGI rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:BeatToBeatData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Guzik’s Index, defined as the distance of points above line of identity (LI) to LI divided by the distance of all points in Poincaré plot to LI except those that are located on LI."@en ;
                 rdfs:label "beatToBeatGI"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatHTI
bto:beatToBeatHTI rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "The HRV triangular index, measuring the total number of RR intervals divided by the height of the RR intervals histogram."@en ;
                  rdfs:label "beatToBeatHTI"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatHcvNN
bto:beatToBeatHcvNN rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The median absolute deviation of the RR intervals (MadNN) divided by the median of the absolute differences of their successive differences (MedianNN)."@en ;
                    rdfs:label "beatToBeatHcvNN"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatIALS
bto:beatToBeatIALS rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:BeatToBeatData ;
                   rdfs:range xsd:float ;
                   rdfs:comment "Inverse of the average length of the acceleration/deceleration segments. "@en ;
                   rdfs:label "beatToBeatIALS"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatIqrNN
bto:beatToBeatIqrNN rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The interquartile range (IQR) of the RR intervals. "@en ;
                    rdfs:label "beatToBeatIqrNN"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatMadNN
bto:beatToBeatMadNN rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The median absolute deviation of the RR intervals."@en ;
                    rdfs:label "beatToBeatMadNN"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatMeanNN
bto:beatToBeatMeanNN rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:BeatToBeatData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The mean of the RR intervals."@en ;
                     rdfs:label "beatToBeatMeanNN"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatMedianNN
bto:beatToBeatMedianNN rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:BeatToBeatData ;
                       rdfs:range xsd:float ;
                       rdfs:comment "The median of the absolute values of the successive differences between RR intervals."@en ;
                       rdfs:label "beatToBeatMedianNN"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatPAS
bto:beatToBeatPAS rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Percentage of NN intervals in alternation segments"@en ;
                  rdfs:label "beatToBeatPAS"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatPI
bto:beatToBeatPI rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:BeatToBeatData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Porta’s Index, defined as the number of points below LI divided by the total number of points in Poincaré plot except those that are located on LI."@en ;
                 rdfs:label "beatToBeatPI"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatPIP
bto:beatToBeatPIP rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Percentage of inflection points of the RR intervals series."@en ;
                  rdfs:label "beatToBeatPIP"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatPNN20
bto:beatToBeatPNN20 rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The proportion of RR intervals greater than 20ms, out of the total number of RR intervals."@en ;
                    rdfs:label "beatToBeatPNN20"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatPNN50
bto:beatToBeatPNN50 rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The proportion of RR intervals greater than 50ms, out of the total number of RR intervals."@en ;
                    rdfs:label "beatToBeatPNN50"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatPSS
bto:beatToBeatPSS rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Percentage of short segments"@en ;
                  rdfs:label "beatToBeatPSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatRmssd
bto:beatToBeatRmssd rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The square root of the mean of the sum of successive differences between adjacent RR intervals."@en ;
                    rdfs:label "beatToBeatRmssd"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSD1
bto:beatToBeatSD1 rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "SD1 is a measure of the spread of RR intervals on the Poincaré plot perpendicular to the line of identity. It is an index of short-term RR interval fluctuations, i.e., beat-to-beat variability. It is equivalent (although on another scale) to RMSSD, and therefore it is redundant to report correlations with both (Ciccone, 2017)."@en ;
                  rdfs:label "beatToBeatSD1"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSD1SD2
bto:beatToBeatSD1SD2 rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:BeatToBeatData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The ratio between short- and long-term fluctuations of the RR intervals (SD1 divided by SD2)."@en ;
                     rdfs:label "beatToBeatSD1SD2"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSD1a
bto:beatToBeatSD1a rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:BeatToBeatData ;
                   rdfs:range xsd:float ;
                   rdfs:comment "Short-term variance of contributions of accelerations (shortenings of RR intervals) (Piskorski, 2011)."@en ;
                   rdfs:label "beatToBeatSD1a"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSD1d
bto:beatToBeatSD1d rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:BeatToBeatData ;
                   rdfs:range xsd:float ;
                   rdfs:comment "Short-term variance of contributions of decelerations (prolongations of RR intervals) (Piskorski, 2011)."@en ;
                   rdfs:label "beatToBeatSD1d"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSD2
bto:beatToBeatSD2 rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:BeatToBeatData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Measure of the spread of RR intervals on the Poincaré plot along the line of identity. It is an index of long-term RR interval fluctuations. "@en ;
                  rdfs:label "beatToBeatSD2"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDANN1
bto:beatToBeatSDANN1 rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:BeatToBeatData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The standard deviation of average RR intervals extracted from 1-minute segments of time series data."@en ;
                     rdfs:label "beatToBeatSDANN1"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDANN2
bto:beatToBeatSDANN2 rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:BeatToBeatData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The standard deviation of average RR intervals extracted from 2-minutes segments of time series data."@en ;
                     rdfs:label "beatToBeatSDANN2"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDANN5
bto:beatToBeatSDANN5 rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:BeatToBeatData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The standard deviation of average RR intervals extracted from 5-minutes segments of time series data."@en ;
                     rdfs:label "beatToBeatSDANN5"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDNN
bto:beatToBeatSDNN rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:BeatToBeatData ;
                   rdfs:range xsd:float ;
                   rdfs:comment "The standard deviation of the RR intervals."@en ;
                   rdfs:label "beatToBeatSDNN"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDNNI
bto:beatToBeatSDNNI rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The mean of the standard deviations of RR intervals extracted from 2-minutes segments of time series data."@en ;
                    rdfs:label "beatToBeatSDNNI"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDNNI1
bto:beatToBeatSDNNI1 rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:BeatToBeatData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The mean of the standard deviations of RR intervals extracted from 1-minute segments of time series data."@en ;
                     rdfs:label "beatToBeatSDNNI1"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDNNI5
bto:beatToBeatSDNNI5 rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:BeatToBeatData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The mean of the standard deviations of RR intervals extracted from 5-minutes segments of time series data."@en ;
                     rdfs:label "beatToBeatSDNNI5"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDNNa
bto:beatToBeatSDNNa rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "Total variance of contributions of accelerations (shortenings of RR intervals) (Piskorski, 2011)."@en ;
                    rdfs:label "beatToBeatSDNNa"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDNNd
bto:beatToBeatSDNNd rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:BeatToBeatData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "Total variance of contributions of decelerations (prolongations of RR intervals) (Piskorski, 2011)."@en ;
                    rdfs:label "beatToBeatSDNNd"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSDSD
bto:beatToBeatSDSD rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:BeatToBeatData ;
                   rdfs:range xsd:float ;
                   rdfs:comment "The standard deviation of the successive differences between RR intervals."@en ;
                   rdfs:label "beatToBeatSDSD"@en .


###  https://w3id.org/brainteaser/ontology/schema/beatToBeatSI
bto:beatToBeatSI rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:BeatToBeatData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Slope Index, defined as the phase angle of points above LI divided by the phase angle of all points in Poincaré plot except those that are located on LI."@en ;
                 rdfs:label "beatToBeatSI"@en .


###  https://w3id.org/brainteaser/ontology/schema/before20Years
bto:before20Years rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:Smoking ;
                  rdfs:range xsd:boolean ;
                  rdfs:comment "Whether a patient smoked before the age of 20."@en ;
                  rdfs:label "before20Years"@en .


###  https://w3id.org/brainteaser/ontology/schema/birthYear
bto:birthYear rdf:type owl:DatatypeProperty ,
                       owl:FunctionalProperty ;
              rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
              rdfs:range xsd:gYear ;
              dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2826771" ;
              rdfs:comment "The year in which a person was born. [Definition Source: NCI]"@en ;
              rdfs:label "birthYear"@en .


###  https://w3id.org/brainteaser/ontology/schema/bmrKilocalories
bto:bmrKilocalories rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:PhysicalActivityData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "BMR kilocalories registered by the wearable device. [uom: kcal]"@en ;
                    rdfs:label "bmrKilocalories"@en .


###  https://w3id.org/brainteaser/ontology/schema/bmvtrTotal
bto:bmvtrTotal rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:BVMTR ;
               rdfs:range xsd:integer ;
               rdfs:comment "Brief Visuospatial Memory Test-Revised Total Score."@en ;
               rdfs:label "bmvtrTotal"@en .


###  https://w3id.org/brainteaser/ontology/schema/bodyMassIndex
bto:bodyMassIndex rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:ClinicalEvaluation ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Weight in kilograms divided by the square of the height in metres, used esp. as an indicator of obesity or general nutritional status; also called Quetelet index; abbreviated BMI. [Definition Source: Oxford English Dictionary]"@en ;
                  rdfs:label "bodyMassIndex"@en .


###  https://w3id.org/brainteaser/ontology/schema/bowelAndBladderEDSS
bto:bowelAndBladderEDSS rdf:type owl:DatatypeProperty ,
                                 owl:FunctionalProperty ;
                        rdfs:domain bto:EDSS ;
                        rdfs:range xsd:integer ;
                        rdfs:comment "Expanded Disability Status Score (EDSS) score for bowel and bladder functions."@en ;
                        rdfs:label "bowelAndBladderEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/bowelAndBladderRelapse
bto:bowelAndBladderRelapse rdf:type owl:DatatypeProperty ,
                                    owl:FunctionalProperty ;
                           rdfs:domain bto:Relapse ;
                           rdfs:range xsd:boolean ;
                           rdfs:comment "Whether the relapse involved bowel and bladder functions."@en ;
                           rdfs:label "bowelAndBladderRelapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/brainAtrophyMRI
bto:brainAtrophyMRI rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:MRI ;
                    rdfs:range [ rdf:type rdfs:Datatype ;
                                 owl:oneOf [ rdf:type rdf:List ;
                                             rdf:first "high" ;
                                             rdf:rest [ rdf:type rdf:List ;
                                                        rdf:first "mild" ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "moderate" ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "none" ;
                                                                              rdf:rest rdf:nil
                                                                            ]
                                                                 ]
                                                      ]
                                           ]
                               ] ;
                    rdfs:comment "The level of brain atrophy (cerebral atrophy) found in the brain of the patient shown by the MRI."@en ;
                    rdfs:label "brainAtrophyMRI"@en .


###  https://w3id.org/brainteaser/ontology/schema/brainsetmRelapse
bto:brainsetmRelapse rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:Relapse ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether the relapse involved the brainstem functions."@en ;
                     rdfs:label "brainstemRelapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/brainstemEDSS
bto:brainstemEDSS rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:EDSS ;
                  rdfs:range xsd:integer ;
                  rdfs:comment "Expanded Disability Status Score (EDSS) score for brainstem functions."@en ;
                  rdfs:label "brainstemEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/bulbarOnset
bto:bulbarOnset rdf:type owl:DatatypeProperty ,
                         owl:FunctionalProperty ;
                rdfs:domain bto:Onset ;
                rdfs:range xsd:boolean ;
                rdfs:comment "Whether the patient experienced bulbar onset, which means he or she first notice speech or swallowing problems. [Definition Source: National Institute of Neurological Disorders and Stroke]"@en ;
                rdfs:label "bulbarOnset"@en .


###  https://w3id.org/brainteaser/ontology/schema/bulbarSubscore
bto:bulbarSubscore rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:ALSFRS ;
                   rdfs:range xsd:integer ;
                   rdfs:comment "Bulbar ALSFRS subscore. Sum of items: 1, 2 and 3."@en ;
                   rdfs:label "bulbarSubscore"@en .


###  https://w3id.org/brainteaser/ontology/schema/burdenT1Lesions
bto:burdenT1Lesions rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:MRI ;
                    rdfs:range [ rdf:type rdfs:Datatype ;
                                 owl:oneOf [ rdf:type rdf:List ;
                                             rdf:first "High"@en ;
                                             rdf:rest [ rdf:type rdf:List ;
                                                        rdf:first "Mild"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Moderate"@en ;
                                                                   rdf:rest rdf:nil
                                                                 ]
                                                      ]
                                           ]
                               ] ;
                    rdfs:comment "The burden of T2 lesions showed in the MRI."@en ;
                    rdfs:label "burdenT1Lesions"@en .


###  https://w3id.org/brainteaser/ontology/schema/burdenT2Lesions
bto:burdenT2Lesions rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:MRI ;
                    rdfs:range [ rdf:type rdfs:Datatype ;
                                 owl:oneOf [ rdf:type rdf:List ;
                                             rdf:first "High"@en ;
                                             rdf:rest [ rdf:type rdf:List ;
                                                        rdf:first "Mild"@en ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "Moderate"@en ;
                                                                   rdf:rest rdf:nil
                                                                 ]
                                                      ]
                                           ]
                               ] ;
                    rdfs:comment "The burden of T1 lesions showed in the MRI."@en ;
                    rdfs:label "burdenT2Lesions"@en .


###  https://w3id.org/brainteaser/ontology/schema/bvmtrTrial1
bto:bvmtrTrial1 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:BVMTR ;
                rdfs:range xsd:integer ;
                rdfs:comment "Brief Visuospatial Memory Test-Revised Immediate Recall Trial 1 Score."@en ;
                rdfs:label "bvmtrTrial1"@en .


###  https://w3id.org/brainteaser/ontology/schema/bvmtrTrial2
bto:bvmtrTrial2 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:BVMTR ;
                rdfs:range xsd:integer ;
                rdfs:comment "Brief Visuospatial Memory Test-Revised Immediate Recall Trial 2 Score."@en ;
                rdfs:label "bvmtrTrial2"@en .


###  https://w3id.org/brainteaser/ontology/schema/bvmtrTrial3
bto:bvmtrTrial3 rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:BVMTR ;
                rdfs:range xsd:integer ;
                rdfs:comment "Brief Visuospatial Memory Test-Revised Immediate Recall Trial 3 Score."@en ;
                rdfs:label "bvmtrTrial3"@en .


###  https://w3id.org/brainteaser/ontology/schema/cardiacDisease
bto:cardiacDisease rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:ALSBrainteaserComorbidities ;
                   rdfs:range xsd:boolean ;
                   rdfs:comment "Whether a patient ever had a cardiac disease."@en ;
                   rdfs:label "cardiacDisease"@en .


###  https://w3id.org/brainteaser/ontology/schema/cerebellarEDSS
bto:cerebellarEDSS rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:EDSS ;
                   rdfs:range xsd:integer ;
                   rdfs:comment "Expanded Disability Status Score (EDSS) score for cerebellar functions."@en ;
                   rdfs:label "cerebellarEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/cerebellarRelapse
bto:cerebellarRelapse rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:Relapse ;
                      rdfs:range xsd:boolean ;
                      rdfs:comment "Whether the relapse involved the celebellar functions."@en ;
                      rdfs:label "cerebellarRelapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/cerebralEDSS
bto:cerebralEDSS rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:EDSS ;
                 rdfs:range xsd:integer ;
                 rdfs:comment "Expanded Disability Status Score (EDSS) score for cerebral functions."@en ;
                 rdfs:label "cerebralEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/cervicalSpineSurgery
bto:cervicalSpineSurgery rdf:type owl:DatatypeProperty ;
                         rdfs:domain [ rdf:type owl:Class ;
                                       owl:unionOf ( bto:Last5YearsEvent
                                                     bto:MoreThan5YearsEvent
                                                   )
                                     ] ;
                         rdfs:range xsd:boolean ;
                         rdfs:comment "Whether a patient had a cervical spine surgery."@en ;
                         rdfs:label "cervicalSpineSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/cervicalTrauma
bto:cervicalTrauma rdf:type owl:DatatypeProperty ;
                   rdfs:domain [ rdf:type owl:Class ;
                                 owl:unionOf ( bto:Last5YearsEvent
                                               bto:MoreThan5YearsEvent
                                             )
                               ] ;
                   rdfs:range xsd:boolean ;
                   rdfs:comment "Whether a patient had a cervical trauma."@en ;
                   rdfs:label "cervicalTrauma"@en .


###  https://w3id.org/brainteaser/ontology/schema/clinicalTrialDescription
bto:clinicalTrialDescription rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:ClinicalTrial ;
                             rdfs:range rdf:PlainLiteral ;
                             rdfs:comment "The description of a clinical trial."@en ;
                             rdfs:label "clinicalTrialDescription"@en .


###  https://w3id.org/brainteaser/ontology/schema/clinicallyEvaluatedEDSS
bto:clinicallyEvaluatedEDSS rdf:type owl:DatatypeProperty ,
                                     owl:FunctionalProperty ;
                            rdfs:domain bto:EDSS ;
                            rdfs:range xsd:float ;
                            rdfs:comment "Expanded Disability Status Score (EDSS) evaluated by the physician."@en ;
                            rdfs:label "clinicallyEvaluatedEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/cognitivePhenotype
bto:cognitivePhenotype rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:Patient ;
                       rdfs:range rdf:PlainLiteral ;
                       rdfs:comment "Cognitive phenotype is defined as the broad set of measurable parameters associated with cognition, including not only behavioral symptoms and specific neurocognitive probes, but also physiological and structural indices which we can use to characterize cognitive function at the neural systems. [Source: doi.org/10.1007/978-1-4614-3846-5_4]"@en ;
                       rdfs:label "cognitivePhenotype"@en .


###  https://w3id.org/brainteaser/ontology/schema/cognitiveRelapse
bto:cognitiveRelapse rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:Relapse ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether the relapse involved the mental functions."@en ;
                     rdfs:label "cognitiveRelapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/comorbiditySeverity
bto:comorbiditySeverity rdf:type owl:DatatypeProperty ,
                                 owl:FunctionalProperty ;
                        rdfs:domain bto:Comorbidity ;
                        rdfs:range [ rdf:type rdfs:Datatype ;
                                     owl:oneOf [ rdf:type rdf:List ;
                                                 rdf:first "life risk" ;
                                                 rdf:rest [ rdf:type rdf:List ;
                                                            rdf:first "moderate" ;
                                                            rdf:rest [ rdf:type rdf:List ;
                                                                       rdf:first "serious" ;
                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                  rdf:first "slight" ;
                                                                                  rdf:rest rdf:nil
                                                                                ]
                                                                     ]
                                                          ]
                                               ]
                                   ] ;
                        rdfs:comment "The severity of a comorbidity."@en ;
                        rdfs:label "comorbiditySeverity"@en .


###  https://w3id.org/brainteaser/ontology/schema/comorbidityTreatment
bto:comorbidityTreatment rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:Comorbidity ;
                         rdfs:range rdf:PlainLiteral ;
                         rdfs:comment "The treatment used for the comorbidity."@en ;
                         rdfs:label "comorbidityTreatment"@en .


###  https://w3id.org/brainteaser/ontology/schema/componentName
bto:componentName rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:LaboratoryTestResult ;
                  rdfs:range rdf:PlainLiteral ;
                  rdfs:comment "The name of the hematopoietic component tested in the laboratory test result."@en ;
                  rdfs:label "componentName"@en .


###  https://w3id.org/brainteaser/ontology/schema/concentrationMeasurement
bto:concentrationMeasurement rdf:type owl:DatatypeProperty ;
                             rdfs:domain [ rdf:type owl:Class ;
                                           owl:unionOf ( <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration>
                                                         bto:WeatherData
                                                       )
                                         ] ;
                             rdfs:range xsd:float ;
                             rdfs:comment "Raw air pollution concentration measured by the Sensing Device."@en ;
                             rdfs:label "concentrationMeasurement"@en .


###  https://w3id.org/brainteaser/ontology/schema/conditionEnd
bto:conditionEnd rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:Condition ;
                 rdfs:range xsd:date ;
                 rdfs:comment "The calendar date of the end of the registered conditon."@en ;
                 rdfs:label "conditionEnd"@en .


###  https://w3id.org/brainteaser/ontology/schema/conditionStart
bto:conditionStart rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:Condition ;
                   rdfs:range xsd:date ;
                   dcterms:title "The calendar date of the start of the registered conditon."@en ;
                   rdfs:label "conditionStart"@en .


###  https://w3id.org/brainteaser/ontology/schema/contiguousLesionsMRI
bto:contiguousLesionsMRI rdf:type owl:DatatypeProperty ,
                                  owl:FunctionalProperty ;
                         rdfs:domain bto:MRI ;
                         rdfs:range xsd:boolean ;
                         rdfs:comment "Whether the MRI detected the presence of extended contiguous lesions equal to or greater than three vertical segments."@en ;
                         rdfs:label "contiguousLesionsMRI"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITotalCorrect
bto:cvltIITotalCorrect rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:CVLTII ;
                       rdfs:range xsd:integer ;
                       rdfs:comment "California Verbal Learning Test Total Corrected Score."@en ;
                       rdfs:label "cvltIITotalCorrect"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITotalInterferences
bto:cvltIITotalInterferences rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:CVLTII ;
                             rdfs:range xsd:integer ;
                             rdfs:comment "California Verbal Learning Test Total Interferences Score."@en ;
                             rdfs:label "cvltIITotalInterferences"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITotalPerseverations
bto:cvltIITotalPerseverations rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:CVLTII ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "California Verbal Learning Test Total Perseverations Score."@en ;
                              rdfs:label "cvltIITotalPerseverations"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial1Correct
bto:cvltIITrial1Correct rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:CVLTII ;
                        rdfs:range xsd:integer ;
                        rdfs:comment "California Verbal Learning Test Trial 1 Corrected Score."@en ;
                        rdfs:label "cvltIITrial1Correct"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial1Interferences
bto:cvltIITrial1Interferences rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:CVLTII ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "California Verbal Learning Test Trial 1 Interferences Score."@en ;
                              rdfs:label "cvltIITrial1Interferences"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial1Perseverations
bto:cvltIITrial1Perseverations rdf:type owl:DatatypeProperty ;
                               rdfs:domain bto:CVLTII ;
                               rdfs:range xsd:integer ;
                               rdfs:comment "California Verbal Learning Test Trial 1 Perseverations Score."@en ;
                               rdfs:label "cvltIITrial1Perseverations"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial2Correct
bto:cvltIITrial2Correct rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:CVLTII ;
                        rdfs:range xsd:integer ;
                        rdfs:comment "California Verbal Learning Test Trial 2 Corrected Score."@en ;
                        rdfs:label "cvltIITrial2Correct"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial2Interferences
bto:cvltIITrial2Interferences rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:CVLTII ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "California Verbal Learning Test Trial 2 Interferences Score."@en ;
                              rdfs:label "cvltIITrial2Interferences"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial2Perseverations
bto:cvltIITrial2Perseverations rdf:type owl:DatatypeProperty ;
                               rdfs:domain bto:CVLTII ;
                               rdfs:range xsd:integer ;
                               rdfs:comment "California Verbal Learning Test Trial 2 Perseverations Score."@en ;
                               rdfs:label "cvltIITrial2Perseverations"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial3Correct
bto:cvltIITrial3Correct rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:CVLTII ;
                        rdfs:range xsd:integer ;
                        rdfs:comment "California Verbal Learning Test Trial 3 Corrected Score."@en ;
                        rdfs:label "cvltIITrial3Correct"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial3Interferences
bto:cvltIITrial3Interferences rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:CVLTII ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "California Verbal Learning Test Trial 3 Interferences Score."@en ;
                              rdfs:label "cvltIITrial3Interferences"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial3Perseverations
bto:cvltIITrial3Perseverations rdf:type owl:DatatypeProperty ;
                               rdfs:domain bto:CVLTII ;
                               rdfs:range xsd:integer ;
                               rdfs:comment "California Verbal Learning Test Trial 3 Perseverations Score."@en ;
                               rdfs:label "cvltIITrial3Perseverations"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial4Correct
bto:cvltIITrial4Correct rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:CVLTII ;
                        rdfs:range xsd:integer ;
                        rdfs:comment "California Verbal Learning Test Trial 4 Corrected Score."@en ;
                        rdfs:label "cvltIITrial4Correct"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial4Interferences
bto:cvltIITrial4Interferences rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:CVLTII ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "California Verbal Learning Test Trial 4 Interferences Score."@en ;
                              rdfs:label "cvltIITrial4Interferences"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial4Perseverations
bto:cvltIITrial4Perseverations rdf:type owl:DatatypeProperty ;
                               rdfs:domain bto:CVLTII ;
                               rdfs:range xsd:integer ;
                               rdfs:comment "California Verbal Learning Test Trial 4 Perseverations Score."@en ;
                               rdfs:label "cvltIITrial4Perseverations"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial5Correct
bto:cvltIITrial5Correct rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:CVLTII ;
                        rdfs:range xsd:integer ;
                        rdfs:comment "California Verbal Learning Test Trial 5 Corrected Score."@en ;
                        rdfs:label "cvltIITrial5Correct"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial5Interferences
bto:cvltIITrial5Interferences rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:CVLTII ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "California Verbal Learning Test Trial 5 Interferences Score."@en ;
                              rdfs:label "cvltIITrial5Interferences"@en .


###  https://w3id.org/brainteaser/ontology/schema/cvltIITrial5Perseverations
bto:cvltIITrial5Perseverations rdf:type owl:DatatypeProperty ;
                               rdfs:domain bto:CVLTII ;
                               rdfs:range xsd:integer ;
                               rdfs:comment "California Verbal Learning Test Trial 5 Perseverations Score."@en ;
                               rdfs:label "cvltIITrial5Perseverations"@en .


###  https://w3id.org/brainteaser/ontology/schema/dailyCigarettes
bto:dailyCigarettes rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:Smoking ;
                    rdfs:range xsd:integer ;
                    rdfs:comment "The number of cigarettes smoked in one day on average."@en ;
                    rdfs:label "dailyCigarettes"@en .


###  https://w3id.org/brainteaser/ontology/schema/deathCause
bto:deathCause rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
               rdfs:range rdf:PlainLiteral ;
               dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007465"@en ;
               rdfs:comment "The circumstance or condition that results in the death of a living being. [Definition Source: NCI]"@en ;
               rdfs:label "deathCause"@en .


###  https://w3id.org/brainteaser/ontology/schema/deathDate
bto:deathDate rdf:type owl:DatatypeProperty ,
                       owl:FunctionalProperty ;
              rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
              rdfs:range xsd:date ;
              dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1148348"@en ;
              rdfs:comment "The calendar date of subject's death. [Definition Source: NCI]"@en ;
              rdfs:label "deathDate"@en .


###  https://w3id.org/brainteaser/ontology/schema/deepSleepDuration
bto:deepSleepDuration rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:SleepData ;
                      rdfs:range xsd:float ;
                      rdfs:comment "Deep sleep duration registered by the wearable device. [uom: seconds]"@en ;
                      rdfs:label "deepSleepDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/dextricity
bto:dextricity rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:Patient ;
               rdfs:range xsd:integer ;
               dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0449722"@en ;
               rdfs:comment "The preferred hand of use for controlled and efficient performance of motor tasks. [Definition Source: NCI]"@en ;
               rdfs:label "dextricity"@en .


###  https://w3id.org/brainteaser/ontology/schema/diabetes
bto:diabetes rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:ALSBrainteaserComorbidities ;
             rdfs:range xsd:boolean ;
             rdfs:comment "Whether a patient ever had diabetes."@en ;
             rdfs:label "diabetes"@en .


###  https://w3id.org/brainteaser/ontology/schema/diagnosticCriteria
bto:diagnosticCriteria rdf:type owl:DatatypeProperty ,
                                owl:FunctionalProperty ;
                       rdfs:domain bto:Diagnosis ;
                       rdfs:range rdf:PlainLiteral ;
                       dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0679228"@en ;
                       rdfs:comment "A standard from which a judgment concerning a medical diagnosis can be established. [Definition Source: NCI]"@en ;
                       rdfs:label "diagnosticCriteria"@en .


###  https://w3id.org/brainteaser/ontology/schema/diagnosticCriteriaLabel
bto:diagnosticCriteriaLabel rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:Diagnosis ;
                            rdfs:range rdf:PlainLiteral ;
                            rdfs:comment "Criteria for the diagnosis. Possible values are: {Diagnosed MS, Neuromyelitis optica, NA}"@en ;
                            rdfs:label "diagnosticCriteriaLabel"@en .


###  https://w3id.org/brainteaser/ontology/schema/diagnosticDelay
bto:diagnosticDelay rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:Diagnosis ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The Difference (in days) between the date of diagnosis and the date of onset. (diagnosis_date-onset_date)"@en ;
                    rdfs:label "diagnosticDelay"@en .


###  https://w3id.org/brainteaser/ontology/schema/diet
bto:diet rdf:type owl:DatatypeProperty ,
                  owl:FunctionalProperty ;
         rdfs:domain bto:Lifestyle ;
         rdfs:range rdf:PlainLiteral ;
         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0012155"@en ;
         rdfs:comment "Regular course of eating and drinking adopted by a person or animal. [Definition Source: MSH]"@en ;
         rdfs:label "diet"@en .


###  https://w3id.org/brainteaser/ontology/schema/dominantHandTrial1
bto:dominantHandTrial1 rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:HandDexterity ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Hand Dextrcity on dominant hand (Trial 1)."@en ;
                       rdfs:label "dominantHandTrial1"@en .


###  https://w3id.org/brainteaser/ontology/schema/dominantHandTrial2
bto:dominantHandTrial2 rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:HandDexterity ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Hand Dextrcity on dominant hand (Trial 2)."@en ;
                       rdfs:label "dominantHandTrial2"@en .


###  https://w3id.org/brainteaser/ontology/schema/dominantHandTrialDone
bto:dominantHandTrialDone rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:HandDexterity ;
                          rdfs:range xsd:boolean ;
                          rdfs:comment "Whether the hand dextricity was performed on the dominant hand."@en ;
                          rdfs:label "dominantHandTrialDone"@en .


###  https://w3id.org/brainteaser/ontology/schema/dyslipidemia
bto:dyslipidemia rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:ALSBrainteaserComorbidities ;
                 rdfs:range xsd:boolean ;
                 rdfs:comment "Whether a patient ever had dyslipidemia."@en ;
                 rdfs:label "dyslipidemia"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasALSnonSpecificScore
bto:ecasALSnonSpecificScore rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:ECAS ;
                            rdfs:range xsd:integer ;
                            rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen ALS non-specific Score."@en ;
                            rdfs:label "ecasALSnonSpecificScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasALSspecificScore
bto:ecasALSspecificScore rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:ECAS ;
                         rdfs:range xsd:integer ;
                         rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen ALS-specific Score."@en ;
                         rdfs:label "ecasALSspecificScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasCarerInterviewScore
bto:ecasCarerInterviewScore rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:ECAS ;
                            rdfs:range xsd:integer ;
                            rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Carer Interview Score."@en ;
                            rdfs:label "ecasCarerInterviewScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasExecutiveAlternation
bto:ecasExecutiveAlternation rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:ECAS ;
                             rdfs:range xsd:integer ;
                             rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Executive Alteration score."@en ;
                             rdfs:label "ecasExecutiveAlternation"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasExecutiveFluencyS
bto:ecasExecutiveFluencyS rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:ECAS ;
                          rdfs:range xsd:integer ;
                          rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Executive Fluency of Letter S Score."@en ;
                          rdfs:label "ecasExecutiveFluencyS"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasExecutiveFluencyT
bto:ecasExecutiveFluencyT rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:ECAS ;
                          rdfs:range xsd:integer ;
                          rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Executive Fluency of Letter T Score."@en ;
                          rdfs:label "ecasExecutiveFluencyT"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasExecutiveScore
bto:ecasExecutiveScore rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:ECAS ;
                       rdfs:range xsd:integer ;
                       rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Executive Score."@en ;
                       rdfs:label "ecasExecutiveScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasExecutiveSentenceCompletion
bto:ecasExecutiveSentenceCompletion rdf:type owl:DatatypeProperty ;
                                    rdfs:domain bto:ECAS ;
                                    rdfs:range xsd:integer ;
                                    rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Executive Sentence Completion Score."@en ;
                                    rdfs:label "ecasExecutiveSentenceCompletion"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasHasCarerInterview
bto:ecasHasCarerInterview rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:ECAS ;
                          rdfs:range xsd:boolean ;
                          rdfs:comment "Whether during the ECAS test a carer interview was performed."@en ;
                          rdfs:label "ecasHasCarerInterview"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasLanguageComprehension
bto:ecasLanguageComprehension rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:ECAS ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Language Comprehension Score."@en ;
                              rdfs:label "ecasLanguageComprehension"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasLanguageNaming
bto:ecasLanguageNaming rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:ECAS ;
                       rdfs:range xsd:integer ;
                       rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Language Naming Score."@en ;
                       rdfs:label "ecasLanguageNaming"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasLanguageScore
bto:ecasLanguageScore rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:ECAS ;
                      rdfs:range xsd:integer ;
                      rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Language Score."@en ;
                      rdfs:label "ecasLanguageScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasLanguageSpelling
bto:ecasLanguageSpelling rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:ECAS ;
                         rdfs:range xsd:integer ;
                         rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Language Spelling score."@en ;
                         rdfs:label "ecasLanguageSpelling"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasMemoryDelayedRecall
bto:ecasMemoryDelayedRecall rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:ECAS ;
                            rdfs:range xsd:integer ;
                            rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Memory Delayed Recall Score."@en ;
                            rdfs:label "ecasMemoryDelayedRecall"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasMemoryDelayedRecognition
bto:ecasMemoryDelayedRecognition rdf:type owl:DatatypeProperty ;
                                 rdfs:domain bto:ECAS ;
                                 rdfs:range xsd:boolean ;
                                 rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Memory Delayed Recognition Score."@en ;
                                 rdfs:label "ecasMemoryDelayedRecognition"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasMemoryImmediateRecall
bto:ecasMemoryImmediateRecall rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:ECAS ;
                              rdfs:range xsd:integer ;
                              rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Memory Immediate Recall Score."@en ;
                              rdfs:label "ecasMemoryImmediateRecall"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasMemoryScore
bto:ecasMemoryScore rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:ECAS ;
                    rdfs:range xsd:integer ;
                    rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Memory Score."@en ;
                    rdfs:label "ecasMemoryScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasPsychosisScreenScore
bto:ecasPsychosisScreenScore rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:ECAS ;
                             rdfs:range xsd:integer ;
                             rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Psychosis Screen Score."@en ;
                             rdfs:label "ecasPsychosisScreenScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasReverseDigitSpan
bto:ecasReverseDigitSpan rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:ECAS ;
                         rdfs:range xsd:integer ;
                         rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Reverse Digit Span Score."@en ;
                         rdfs:label "ecasReverseDigitSpan"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasSocialCognition
bto:ecasSocialCognition rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:ECAS ;
                        rdfs:range xsd:integer ;
                        rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Social Cognition Score."@en ;
                        rdfs:label "ecasSocialCognition"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasSymptomsApathyOrInertia
bto:ecasSymptomsApathyOrInertia rdf:type owl:DatatypeProperty ;
                                rdfs:domain bto:ECAS ;
                                rdfs:range xsd:integer ;
                                rdfs:comment "Whether the patient presents apathy or inertia symptoms."@en ;
                                rdfs:label "ecasSymptomsApathyOrInertia"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasSymptomsChangePrevBehaviour
bto:ecasSymptomsChangePrevBehaviour rdf:type owl:DatatypeProperty ;
                                    rdfs:domain bto:ECAS ;
                                    rdfs:range xsd:boolean ;
                                    rdfs:comment "Whether the patient presents symptoms change from previous behaviour."@en ;
                                    rdfs:label "ecasSymptomsChangePrevBehaviour"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasSymptomsDisinhibition
bto:ecasSymptomsDisinhibition rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:ECAS ;
                              rdfs:range xsd:boolean ;
                              rdfs:comment "Whether the patient presents disinhibition symptoms."@en ;
                              rdfs:label "ecasSymptomsDisinhibition"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasSymptomsHyperorality
bto:ecasSymptomsHyperorality rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:ECAS ;
                             rdfs:range xsd:boolean ;
                             rdfs:comment "Whether the patient presents hyperorality symptoms."@en ;
                             rdfs:label "ecasSymptomsHyperorality"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasSymptomsLossSympathyOrEmpathy
bto:ecasSymptomsLossSympathyOrEmpathy rdf:type owl:DatatypeProperty ;
                                      rdfs:domain bto:ECAS ;
                                      rdfs:range xsd:boolean ;
                                      rdfs:comment "Whether the patient presents loss sympathy or empathy symptoms."@en ;
                                      rdfs:label "ecasSymptomsLossSympathyOrEmpathy"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasSymptomsPerseverativeSterotyped
bto:ecasSymptomsPerseverativeSterotyped rdf:type owl:DatatypeProperty ;
                                        rdfs:domain bto:ECAS ;
                                        rdfs:range xsd:boolean ;
                                        rdfs:comment "Whether the patient presents perseverative stereotyped symptoms."@en ;
                                        rdfs:label "ecasSymptomsPerseverativeSterotyped"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasTotalScore
bto:ecasTotalScore rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:ECAS ;
                   rdfs:range xsd:integer ;
                   rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Total Score."@en ;
                   rdfs:label "ecasTotalScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasVerbalFluencyScore
bto:ecasVerbalFluencyScore rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:ECAS ;
                           rdfs:range xsd:integer ;
                           rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Verbal Fluency score."@en ;
                           rdfs:label "ecasVerbalFluencyScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasVisuospatialCubeCounting
bto:ecasVisuospatialCubeCounting rdf:type owl:DatatypeProperty ;
                                 rdfs:domain bto:ECAS ;
                                 rdfs:range xsd:integer ;
                                 rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Visuospatial Cube Counting Score."@en ;
                                 rdfs:label "ecasVisuospatialCubeCounting"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasVisuospatialDotCounting
bto:ecasVisuospatialDotCounting rdf:type owl:DatatypeProperty ;
                                rdfs:domain bto:ECAS ;
                                rdfs:range xsd:integer ;
                                rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Visuospatial Dot Counting Score."@en ;
                                rdfs:label "ecasVisuospatialDotCounting"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasVisuospatialNumberLocation
bto:ecasVisuospatialNumberLocation rdf:type owl:DatatypeProperty ;
                                   rdfs:domain bto:ECAS ;
                                   rdfs:range xsd:integer ;
                                   rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Visuospatial Number Location Score."@en ;
                                   rdfs:label "ecasVisuospatialNumberLocation"@en .


###  https://w3id.org/brainteaser/ontology/schema/ecasVisuospatialScore
bto:ecasVisuospatialScore rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:ECAS ;
                          rdfs:range xsd:integer ;
                          rdfs:comment "Edinburgh Cognitive and Behavioural ALS Screen Visuospatial Score."@en ;
                          rdfs:label "ecasVisuospatialScore"@en .


###  https://w3id.org/brainteaser/ontology/schema/educationLevel
bto:educationLevel rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:Patient ;
                   rdfs:range xsd:int ;
                   dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0013658" ;
                   rdfs:comment "An indication of the years of schooling completed in graded public, private, or parochial schools, and in colleges, universities, or professional schools. [Definition Source: NCI]"@en ;
                   rdfs:label "educationLevel"@en .


###  https://w3id.org/brainteaser/ontology/schema/endReason
bto:endReason rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:ClinicalTrialParticipation ;
              rdfs:range rdf:PlainLiteral ;
              rdfs:comment "The reason for the interruption of the subject's participation in a clinical trial." ;
              rdfs:label "endReason" .


###  https://w3id.org/brainteaser/ontology/schema/endTherapyReason
bto:endTherapyReason rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:EndTherapyReason ;
                     rdfs:range rdf:PlainLiteral ;
                     rdfs:comment "The reason for the interruption of the therapeutic treatment."@en ;
                     rdfs:label "endTherapyReason"@en .


###  https://w3id.org/brainteaser/ontology/schema/eventEnd
bto:eventEnd rdf:type owl:DatatypeProperty ,
                      owl:FunctionalProperty ;
             rdfs:domain bto:Event ;
             rdfs:range xsd:date ;
             rdfs:comment "The calendar date of the end of the event."@en ;
             rdfs:label "eventEnd"@en .


###  https://w3id.org/brainteaser/ontology/schema/eventStart
bto:eventStart rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:Event ;
               rdfs:range xsd:date ;
               rdfs:comment "The calendar date of the start of the event."@en ;
               rdfs:label "eventStart"@en .


###  https://w3id.org/brainteaser/ontology/schema/everSmoked
bto:everSmoked rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:Smoking ;
               rdfs:range xsd:boolean ;
               rdfs:comment "Whether a patient has ever smoked or not."@en ;
               rdfs:label "everSmoked"@en .


###  https://w3id.org/brainteaser/ontology/schema/evokedPotentialsLocation
bto:evokedPotentialsLocation rdf:type owl:DatatypeProperty ,
                                      owl:FunctionalProperty ;
                             rdfs:domain bto:EvokedPotentials ;
                             rdfs:range [ rdf:type rdfs:Datatype ;
                                          owl:oneOf [ rdf:type rdf:List ;
                                                      rdf:first "left" ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "lower" ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "lower left" ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "lower right" ;
                                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                                  rdf:first "right" ;
                                                                                                  rdf:rest [ rdf:type rdf:List ;
                                                                                                             rdf:first "upper" ;
                                                                                                             rdf:rest [ rdf:type rdf:List ;
                                                                                                                        rdf:first "upper left" ;
                                                                                                                        rdf:rest [ rdf:type rdf:List ;
                                                                                                                                   rdf:first "upper right" ;
                                                                                                                                   rdf:rest rdf:nil
                                                                                                                                 ]
                                                                                                                      ]
                                                                                                           ]
                                                                                                ]
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                        ] ;
                             rdfs:comment "The body location of the evoked potential test."@en ;
                             rdfs:label "evokedPotentialsLocation"@en ;
                             skos:note "Locations \"upper left/upper right/lower left/lower right\" can only be used for Evoked Potentials of type 'somatosensory' or 'motor'."@en .


###  https://w3id.org/brainteaser/ontology/schema/evokedPotentialsResponse
bto:evokedPotentialsResponse rdf:type owl:DatatypeProperty ,
                                      owl:FunctionalProperty ;
                             rdfs:domain bto:EvokedPotentials ;
                             rdfs:range [ rdf:type rdfs:Datatype ;
                                          owl:oneOf [ rdf:type rdf:List ;
                                                      rdf:first "altered" ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "normal" ;
                                                                 rdf:rest rdf:nil
                                                               ]
                                                    ]
                                        ] ;
                             rdfs:comment "The evoked potential function test result."@en ;
                             rdfs:label "evokedPotentialsResponse"@en .


###  https://w3id.org/brainteaser/ontology/schema/evokedPotentialsType
bto:evokedPotentialsType rdf:type owl:DatatypeProperty ,
                                  owl:FunctionalProperty ;
                         rdfs:domain bto:EvokedPotentials ;
                         rdfs:range [ rdf:type rdfs:Datatype ;
                                      owl:oneOf [ rdf:type rdf:List ;
                                                  rdf:first "auditory" ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "motor" ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "somatosensory" ;
                                                                        rdf:rest [ rdf:type rdf:List ;
                                                                                   rdf:first "visual" ;
                                                                                   rdf:rest rdf:nil
                                                                                 ]
                                                                      ]
                                                           ]
                                                ]
                                    ] ;
                         rdfs:comment "Whether the test was a Visual Evoked Potential (VEP), Auditory Evoked Potential (AEP), Somatosensory Evoked Potential (SSEP) or Motor Evoked Potential (MEP)."@en ;
                         rdfs:label "evokedPotentialsType"@en .


###  https://w3id.org/brainteaser/ontology/schema/factorsAffectedHandTrial
bto:factorsAffectedHandTrial rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:HandDexterity ;
                             rdfs:range [ rdf:type rdfs:Datatype ;
                                          owl:oneOf [ rdf:type rdf:List ;
                                                      rdf:first "Difficulty seeing"@en ;
                                                      rdf:rest [ rdf:type rdf:List ;
                                                                 rdf:first "Dropped PEG"@en ;
                                                                 rdf:rest [ rdf:type rdf:List ;
                                                                            rdf:first "Has a Cold"@en ;
                                                                            rdf:rest [ rdf:type rdf:List ;
                                                                                       rdf:first "Other"@en ;
                                                                                       rdf:rest [ rdf:type rdf:List ;
                                                                                                  rdf:first "Talked"@en ;
                                                                                                  rdf:rest rdf:nil
                                                                                                ]
                                                                                     ]
                                                                          ]
                                                               ]
                                                    ]
                                        ] ;
                             rdfs:comment "The factors that affected the hand dextricity test."@en ;
                             rdfs:label "factorsAffectedHandTrial"@en .


###  https://w3id.org/brainteaser/ontology/schema/familiarHistoryALS
bto:familiarHistoryALS rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:Patient ;
                       rdfs:range xsd:boolean ;
                       rdfs:comment "Whether someone in the patient's faimily suffered from ALS. This property only applies to ALS patients."@en ;
                       rdfs:label "familiarHistoryALS"@en .


###  https://w3id.org/brainteaser/ontology/schema/floorsClimbed
bto:floorsClimbed rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:PhysicalActivityData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Floors climbed registered by the wearable device."@en ;
                  rdfs:label "floorsClimbed"@en .


###  https://w3id.org/brainteaser/ontology/schema/floorsClimbedGoal
bto:floorsClimbedGoal rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:PhysicalActivityData ;
                      rdfs:range xsd:float ;
                      rdfs:comment "Floors climbed goal registered by the wearable device."@en ;
                      rdfs:label "floorsClimbedGoal"@en .


###  https://w3id.org/brainteaser/ontology/schema/gadoliniumLesionsT1MRI
bto:gadoliniumLesionsT1MRI rdf:type owl:DatatypeProperty ,
                                    owl:FunctionalProperty ;
                           rdfs:domain bto:MRI ;
                           rdfs:range xsd:boolean ;
                           rdfs:comment "Whether the MRI detected some gadolinium-enhanced lesions in T1."@en ;
                           rdfs:label "gadoliniumLesionsT1MRI"@en .


###  https://w3id.org/brainteaser/ontology/schema/gadoliniumLesionsT1MRINumber
bto:gadoliniumLesionsT1MRINumber rdf:type owl:DatatypeProperty ,
                                          owl:FunctionalProperty ;
                                 rdfs:domain bto:MRI ;
                                 rdfs:range xsd:integer ;
                                 rdfs:comment "The number of gadolinium-enhanced lesions in T1."@en ;
                                 rdfs:label "gadoliniumLesionsT1MRINumber"@en .


###  https://w3id.org/brainteaser/ontology/schema/generalizedOnset
bto:generalizedOnset rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:Onset ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether the patient experienced generalized onset, that are widespread symptoms."@en ;
                     rdfs:label "generalizedOnset"@en .


###  https://w3id.org/brainteaser/ontology/schema/genomeSequencing
bto:genomeSequencing rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:Patient ;
                     rdfs:range rdf:PlainLiteral ;
                     dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3640076"@en ;
                     rdfs:comment "A procedure that can determine the DNA sequence for nearly the entire genome of an individual. [Definition Source: NCI]"@en ;
                     rdfs:label "genomeSequencing"@en .


###  https://w3id.org/brainteaser/ontology/schema/glucoseCSF
bto:glucoseCSF rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:CSFAnalysis ;
               rdfs:range xsd:float ;
               rdfs:comment "A quantitative measurement of blood sugar present in a sample of CSF. Unit of measure : [mg/l]."@en ;
               rdfs:label "glucoseCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/goldCoastExcludingOthers
bto:goldCoastExcludingOthers rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:GoldCoastCriteria ;
                             rdfs:range xsd:boolean ;
                             rdfs:comment "Whether other disease processes has been excluded. [Source: doi.org/10.1016/j.clinph.2020.04.005 ]"@en ;
                             rdfs:label "goldCoastExcludingOthers"@en .


###  https://w3id.org/brainteaser/ontology/schema/goldCoastProgressiveMotorImpairment
bto:goldCoastProgressiveMotorImpairment rdf:type owl:DatatypeProperty ;
                                        rdfs:domain bto:GoldCoastCriteria ;
                                        rdfs:range xsd:boolean ;
                                        rdfs:comment "Whether the patient presents progressive motor impairment documented by history or repeated clinical assessment, preceded by normal motor function. [Source: doi.org/10.1016/j.clinph.2020.04.005 ]"@en ;
                                        rdfs:label "goldCoastProgressiveMotorImpairment"@en .


###  https://w3id.org/brainteaser/ontology/schema/goldCoastUMNandLMN
bto:goldCoastUMNandLMN rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:GoldCoastCriteria ;
                       rdfs:range xsd:boolean ;
                       rdfs:comment "Whether the patient presents UMN and LMN signs in at least one body region. [Source: doi.org/10.1016/j.clinph.2020.04.005 ]"@en ;
                       rdfs:label "goldCoastUMNandLMN"@en .


###  https://w3id.org/brainteaser/ontology/schema/granulocytesCSF
bto:granulocytesCSF rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:CSFAnalysis ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The percentage of granulocytes present in a sample of CSF. Unit of measure : [%]."@en ;
                    rdfs:label "granulocytesCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/hadMajorTrauma
bto:hadMajorTrauma rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:BeforeOnset ;
                   rdfs:range xsd:boolean ;
                   rdfs:comment "Whether a patient had a major trauma before the disease onset."@en ;
                   rdfs:label "hadMajorTrauma"@en .


###  https://w3id.org/brainteaser/ontology/schema/hadSurgicalIntervention
bto:hadSurgicalIntervention rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:BeforeOnset ;
                            rdfs:range xsd:boolean ;
                            rdfs:comment "Whether the patient had a surgical intervention before the disease onset."@en ;
                            rdfs:label "hadSurgicalIntervention"@en .


###  https://w3id.org/brainteaser/ontology/schema/hasMenstrualCycle
bto:hasMenstrualCycle rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:MenstrualCycle ;
                      rdfs:range xsd:boolean ;
                      rdfs:comment "Whether the patient has the menstrual cycle."@en ;
                      rdfs:label "hasMenstrualCycle"@en .


###  https://w3id.org/brainteaser/ontology/schema/hasMutation
bto:hasMutation rdf:type owl:DatatypeProperty ,
                         owl:FunctionalProperty ;
                rdfs:domain bto:GeneticTesting ;
                rdfs:range xsd:boolean ;
                rdfs:comment "Whether the gene tested positive or negative for mutations during genetic testing."@en ;
                rdfs:label "hasMutation"@en .


###  https://w3id.org/brainteaser/ontology/schema/headNeckSurgery
bto:headNeckSurgery rdf:type owl:DatatypeProperty ;
                    rdfs:domain [ rdf:type owl:Class ;
                                  owl:unionOf ( bto:Last5YearsEvent
                                                bto:MoreThan5YearsEvent
                                              )
                                ] ;
                    rdfs:range xsd:boolean ;
                    rdfs:comment "Whether a patient had a surgery in the head and neck area."@en ;
                    rdfs:label "headNeckSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/headTrauma
bto:headTrauma rdf:type owl:DatatypeProperty ;
               rdfs:domain [ rdf:type owl:Class ;
                             owl:unionOf ( bto:Last5YearsEvent
                                           bto:MoreThan5YearsEvent
                                         )
                           ] ;
               rdfs:range xsd:boolean ;
               rdfs:comment "Whether a patient had an head trauma."@en ;
               rdfs:label "headTrauma"@en .


###  https://w3id.org/brainteaser/ontology/schema/height
bto:height rdf:type owl:DatatypeProperty ,
                    owl:FunctionalProperty ;
           rdfs:domain bto:ClinicalEvaluation ;
           rdfs:range xsd:float ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0489786"@en ;
           rdfs:comment "Distance or measurement from the base upwards; altitude; stature (of the human body). [Source: Oxford English Dictionary]"@en ;
           rdfs:label "height"@en .


###  https://w3id.org/brainteaser/ontology/schema/highStressDuration
bto:highStressDuration rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:StressLevel ;
                       rdfs:range xsd:float ;
                       rdfs:comment "High stress duration registered by the wearable device. [uom: seconds]"@en ;
                       rdfs:label "highStressDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/homeWalkingStatus
bto:homeWalkingStatus rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:ClinicalEvaluation ;
                      rdfs:range [ rdf:type rdfs:Datatype ;
                                   owl:oneOf [ rdf:type rdf:List ;
                                               rdf:first "Crutches"@en ;
                                               rdf:rest [ rdf:type rdf:List ;
                                                          rdf:first "Fully ambulatory"@en ;
                                                          rdf:rest [ rdf:type rdf:List ;
                                                                     rdf:first "Orthosis"@en ;
                                                                     rdf:rest [ rdf:type rdf:List ;
                                                                                rdf:first "Walker"@em ;
                                                                                rdf:rest [ rdf:type rdf:List ;
                                                                                           rdf:first "Walking stick"@en ;
                                                                                           rdf:rest [ rdf:type rdf:List ;
                                                                                                      rdf:first "Wheelchair"@en ;
                                                                                                      rdf:rest rdf:nil
                                                                                                    ]
                                                                                         ]
                                                                              ]
                                                                   ]
                                                        ]
                                             ]
                                 ] ;
                      rdfs:comment "The ambulatory status of the patient within the house. (e.g., whether they walk on their own or they need assistive devices)"@en ;
                      rdfs:label "homeWalkingStatus"@en .


###  https://w3id.org/brainteaser/ontology/schema/hypertension
bto:hypertension rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:ALSBrainteaserComorbidities ;
                 rdfs:range xsd:boolean ;
                 rdfs:comment "Whether a patient ever had hypertension."@en ;
                 rdfs:label "hypertension"@en .


###  https://w3id.org/brainteaser/ontology/schema/immunoglobulinGCSF
bto:immunoglobulinGCSF rdf:type owl:DatatypeProperty ,
                                owl:FunctionalProperty ;
                       rdfs:domain bto:CSFAnalysis ;
                       rdfs:range xsd:float ;
                       rdfs:comment "A quantitative measurement of Immunoglobulin G (IgG) present in a sample of CSF. Unit of measure : [mg/l]."@en ;
                       rdfs:label "immunoglobulinGCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/intensityDurationGoal
bto:intensityDurationGoal rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:PhysicalActivityData ;
                          rdfs:range xsd:float ;
                          rdfs:comment "Intensity duration goal registered by the wearable device. [uom: seconds]"@en ;
                          rdfs:label "intensityDurationGoal"@en .


###  https://w3id.org/brainteaser/ontology/schema/isMenstrualCycleRegular
bto:isMenstrualCycleRegular rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:MenstrualCycle ;
                            rdfs:range xsd:boolean ;
                            rdfs:comment "Whether the patient has a regular menstrual cycle."@en ;
                            rdfs:label "isMenstrualCycleRegular"@en .


###  https://w3id.org/brainteaser/ontology/schema/kingsValue
bto:kingsValue rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:KingsClinicalStaging ;
               rdfs:range xsd:integer ;
               rdfs:comment "The patient's disease stage according to the King's Staging System."@en ;
               rdfs:label "kingsValue"@en .


###  https://w3id.org/brainteaser/ontology/schema/lesionsT1MRI
bto:lesionsT1MRI rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:MRI ;
                 rdfs:range xsd:boolean ;
                 rdfs:comment "Whether the MRI detected some lesions in T1."@en ;
                 rdfs:label "lesionsT1MRI"@en .


###  https://w3id.org/brainteaser/ontology/schema/lesionsT2MRI
bto:lesionsT2MRI rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:MRI ;
                 rdfs:range xsd:boolean ;
                 rdfs:comment "Whether the MRI detected some lesions in T2."@en ;
                 rdfs:label "lesionsT2MRI"@en .


###  https://w3id.org/brainteaser/ontology/schema/leukocytesCountCSF
bto:leukocytesCountCSF rdf:type owl:DatatypeProperty ,
                                owl:FunctionalProperty ;
                       rdfs:domain bto:CSFAnalysis ;
                       rdfs:range xsd:float ;
                       rdfs:comment "A quantitative measurement of leukocytes present in a sample of CSF. Unit of measure : [/mm3]."@en ;
                       rdfs:label "leukocytesCountCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/lightSleepDuration
bto:lightSleepDuration rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:SleepData ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Light sleep duration registered by the wearable device. [uom: seconds]"@en ;
                       rdfs:label "lightSleepDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/limbsOnset
bto:limbsOnset rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:Onset ;
               rdfs:range xsd:boolean ;
               rdfs:comment "Whether the patient experienced limb onset, which menas symptoms began in the arms or legs. [Definition Source: National Institute of Neurological Disorders and Stroke]"@en ;
               rdfs:label "limbsOnset"@en .


###  https://w3id.org/brainteaser/ontology/schema/linearTrendHeartRate
bto:linearTrendHeartRate rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:HeartRateMeasurement ;
                         rdfs:range xsd:float ;
                         rdfs:comment "The parameter corresponding to the linear trend of heart rate. "@en ;
                         rdfs:label "linearTrendHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/lowStressDuration
bto:lowStressDuration rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:StressLevel ;
                      rdfs:range xsd:float ;
                      rdfs:comment "Low stress duration registered by the wearable device. [uom: seconds]"@en ;
                      rdfs:label "lowStressDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/lowerLimbSurgery
bto:lowerLimbSurgery rdf:type owl:DatatypeProperty ;
                     rdfs:domain [ rdf:type owl:Class ;
                                   owl:unionOf ( bto:Last5YearsEvent
                                                 bto:MoreThan5YearsEvent
                                               )
                                 ] ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether a patient had a lower limb surgery."@en ;
                     rdfs:label "lowerLimbSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/lumboSacralSpineSurgery
bto:lumboSacralSpineSurgery rdf:type owl:DatatypeProperty ;
                            rdfs:domain [ rdf:type owl:Class ;
                                          owl:unionOf ( bto:Last5YearsEvent
                                                        bto:MoreThan5YearsEvent
                                                      )
                                        ] ;
                            rdfs:range xsd:boolean ;
                            rdfs:comment "Whether a patient had a lumbo sacral spine surgery."@en ;
                            rdfs:label "lumboSacralSpineSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/lumboSacralTrauma
bto:lumboSacralTrauma rdf:type owl:DatatypeProperty ;
                      rdfs:domain [ rdf:type owl:Class ;
                                    owl:unionOf ( bto:Last5YearsEvent
                                                  bto:MoreThan5YearsEvent
                                                )
                                  ] ;
                      rdfs:range xsd:boolean ;
                      rdfs:comment "Whether a patient had a lumbo sacral trauma."@en ;
                      rdfs:label "lumboSacralTrauma"@en .


###  https://w3id.org/brainteaser/ontology/schema/lymphocytesCSF
bto:lymphocytesCSF rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:CSFAnalysis ;
                   rdfs:range xsd:float ;
                   rdfs:comment "The percentage of lymphocytes present in a sample of CSF. Unit of measure : [%]."@en ;
                   rdfs:label "lymphocytesCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/maritalStatus
bto:maritalStatus rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:Patient ;
                  rdfs:range rdf:PlainLiteral ;
                  dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0024819"@en ;
                  rdfs:comment "A demographic parameter indicating a person's current conjugal status. [Definition Source: NCI]"@en ;
                  rdfs:label "maritalStatus"@en .


###  https://w3id.org/brainteaser/ontology/schema/maxHeartRate
bto:maxHeartRate rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:HeartRateMeasurement ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Max heart rate registered by the wearable device. [uom: bpm]"@en ;
                 rdfs:label "maxHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/maxStressLevel
bto:maxStressLevel rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:StressLevel ;
                   rdfs:range xsd:float ;
                   rdfs:comment "Max stress level registered by the wearable device."@en ;
                   rdfs:label "maxStressLevel"@en .


###  https://w3id.org/brainteaser/ontology/schema/maxTimeHeartRate
bto:maxTimeHeartRate rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:HeartRateMeasurement ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The time at which maximum heart rate occurs. "@en ;
                     rdfs:label "maxTimeHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/measuredLevel
bto:measuredLevel rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:LaboratoryTestResult ;
                  rdfs:range xsd:float ;
                  rdfs:comment "The level of the hematopoietic component measured in the laboratory test result."@en ;
                  rdfs:label "measuredLevel"@en ;
                  skos:note "This data property is populated only for numeric-valued test results."@en .


###  https://w3id.org/brainteaser/ontology/schema/measurementCalibrated
bto:measurementCalibrated rdf:type owl:DatatypeProperty ;
                          rdfs:domain [ rdf:type owl:Class ;
                                        owl:unionOf ( <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration>
                                                      bto:WeatherData
                                                    )
                                      ] ;
                          rdfs:range xsd:float ;
                          rdfs:comment "Air pollution concentration value with seasonal components and noise removed."@en ;
                          rdfs:label "measurementCalibrated"@en .


###  https://w3id.org/brainteaser/ontology/schema/mediumStressDuration
bto:mediumStressDuration rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:StressLevel ;
                         rdfs:range xsd:float ;
                         rdfs:comment "Medium stress duration registered by the wearable device. [uom: seconds]"@en ;
                         rdfs:label "mediumStressDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/menopauseStatus
bto:menopauseStatus rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:Patient ;
                    rdfs:range xsd:boolean ;
                    dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3829127"@en ;
                    rdfs:comment "An indicator as to whether the female subject is in menopause. [Defintion source: NCI]"@en ;
                    rdfs:label "menopauseStatus"@en .


###  https://w3id.org/brainteaser/ontology/schema/metersWalkedFirstMin
bto:metersWalkedFirstMin rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:WalkTestALS ;
                         rdfs:range xsd:float ;
                         rdfs:comment "How many meters the patient walked in the first minute."@en ;
                         rdfs:label "metersWalkedFirstMin"@en .


###  https://w3id.org/brainteaser/ontology/schema/metersWalkedTwoMins
bto:metersWalkedTwoMins rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:WalkTestALS ;
                        rdfs:range xsd:float ;
                        rdfs:comment "How many meters the patient walked in two minutes."@en ;
                        rdfs:label "metersWalkedTwoMins"@en .


###  https://w3id.org/brainteaser/ontology/schema/minHeartRate
bto:minHeartRate rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:HeartRateMeasurement ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Min heart rate registered by the wearable device. [uom: bpm]"@en ;
                 rdfs:label "minHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/minTimeHeartRate
bto:minTimeHeartRate rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:HeartRateMeasurement ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The time at which minimum heart rate occurs."@en ;
                     rdfs:label "minTimeHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/mitosValue
bto:mitosValue rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:MiToSFunctionalStaging ;
               rdfs:range xsd:integer ;
               rdfs:comment "The patient's disease stage according to the MiToS staging system."@en ;
               rdfs:label "mitosValue"@en .


###  https://w3id.org/brainteaser/ontology/schema/moderateIntensityDuration
bto:moderateIntensityDuration rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:PhysicalActivityData ;
                              rdfs:range xsd:float ;
                              rdfs:comment "Moderate intensity duration registered by the wearable device. [uom: seconds]"@en ;
                              rdfs:label "moderateIntensityDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/moreThan10PercentWeightloss
bto:moreThan10PercentWeightloss rdf:type owl:DatatypeProperty ,
                                         owl:FunctionalProperty ;
                                rdfs:domain bto:ClinicalEvaluation ;
                                rdfs:range xsd:boolean ;
                                rdfs:comment "Whether a patient lost more than 10% of his or her body weight."@en ;
                                rdfs:label "moreThan10PercentWeightloss"@en .


###  https://w3id.org/brainteaser/ontology/schema/motorSubscore
bto:motorSubscore rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:ALSFRS ;
                  rdfs:range xsd:integer ;
                  rdfs:comment "Motor ALSFRS subscore. Sum of items: 4, 5, 6, 7, 8 and 9."@en ;
                  rdfs:label "motorSubscore"@en .


###  https://w3id.org/brainteaser/ontology/schema/multipleSclerosisType
bto:multipleSclerosisType rdf:type owl:DatatypeProperty ,
                                   owl:FunctionalProperty ;
                          rdfs:domain bto:ClinicalEvaluation ;
                          rdfs:range [ rdf:type rdfs:Datatype ;
                                       owl:oneOf [ rdf:type rdf:List ;
                                                   rdf:first "clinically isolated syndrome (CIS)" ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "primary progressive MS (PP)" ;
                                                              rdf:rest [ rdf:type rdf:List ;
                                                                         rdf:first "progressive-relapsing (PR)" ;
                                                                         rdf:rest [ rdf:type rdf:List ;
                                                                                    rdf:first "radiologically isolated syndrome (RIS)" ;
                                                                                    rdf:rest [ rdf:type rdf:List ;
                                                                                               rdf:first "relapsing-remitting MS (RR)" ;
                                                                                               rdf:rest [ rdf:type rdf:List ;
                                                                                                          rdf:first "secondary progressive MS (SP)" ;
                                                                                                          rdf:rest rdf:nil
                                                                                                        ]
                                                                                             ]
                                                                                  ]
                                                                       ]
                                                            ]
                                                 ]
                                     ] ;
                          rdfs:comment "The Multiple Sclerosis (MS) disease course identified in the patient."@en ;
                          rdfs:label "multipleSclerosisType"@en ;
                          skos:note "This data property is used only for MS patients."@en .


###  https://w3id.org/brainteaser/ontology/schema/mutationType
bto:mutationType rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:GeneticTesting ;
                 rdfs:range rdf:PlainLiteral ;
                 rdfs:comment "The type of mutation observed in the gene during genetic testing."@en ;
                 rdfs:label "mutationType" .


###  https://w3id.org/brainteaser/ontology/schema/neckTrauma
bto:neckTrauma rdf:type owl:DatatypeProperty ;
               rdfs:domain [ rdf:type owl:Class ;
                             owl:unionOf ( bto:Last5YearsEvent
                                           bto:MoreThan5YearsEvent
                                         )
                           ] ;
               rdfs:comment "Whether a patient had a neck trauma."@en ;
               rdfs:label "neckTrauma"@en .


###  https://w3id.org/brainteaser/ontology/schema/newOrEnlargedLesionsT2MRI
bto:newOrEnlargedLesionsT2MRI rdf:type owl:DatatypeProperty ,
                                       owl:FunctionalProperty ;
                              rdfs:domain bto:MRI ;
                              rdfs:range xsd:boolean ;
                              rdfs:comment "Whether the MRI detected new or enlarged gadolinium-enhanced lesions in T2 since the last MRI."@en ;
                              rdfs:label "newOrEnlargedLesionsT2MRI"@en .


###  https://w3id.org/brainteaser/ontology/schema/newOrEnlargedLesionsT2MRINumber
bto:newOrEnlargedLesionsT2MRINumber rdf:type owl:DatatypeProperty ,
                                             owl:FunctionalProperty ;
                                    rdfs:domain bto:MRI ;
                                    rdfs:range xsd:integer ;
                                    rdfs:comment "The number of new or enlarged gadolinium-enhanced lesions in T2 since the last MRI."@en ;
                                    rdfs:label "newOrEnlargedLesionsT2MRINumber"@en .


###  https://w3id.org/brainteaser/ontology/schema/nonDominantHandTrial1
bto:nonDominantHandTrial1 rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:HandDexterity ;
                          rdfs:range xsd:float ;
                          rdfs:comment "Hand Dextrcity on non-dominant hand (Trial 1)."@en ;
                          rdfs:label "nonDominantHandTrial1"@en .


###  https://w3id.org/brainteaser/ontology/schema/nonDominantHandTrial2
bto:nonDominantHandTrial2 rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:HandDexterity ;
                          rdfs:range xsd:float ;
                          rdfs:comment "Hand Dextrcity on non-dominant hand (Trial 2)."@en ;
                          rdfs:label "nonDominantHandTrial2"@en .


###  https://w3id.org/brainteaser/ontology/schema/nonDominantHandTrialDone
bto:nonDominantHandTrialDone rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:HandDexterity ;
                             rdfs:range xsd:boolean ;
                             rdfs:comment "Whether the hand dextricity was performed on the dominant hand."@en ;
                             rdfs:label "nonDominantHandTrialDone"@en .


###  https://w3id.org/brainteaser/ontology/schema/normalLevel
bto:normalLevel rdf:type owl:DatatypeProperty ,
                         owl:FunctionalProperty ;
                rdfs:domain bto:LaboratoryTestResult ;
                rdfs:range xsd:boolean ;
                rdfs:comment "Whether the measured level is within the normal range for the tested hematopoietic component."@en ;
                rdfs:label "normalLevel"@en .


###  https://w3id.org/brainteaser/ontology/schema/notes
bto:notes rdf:type owl:DatatypeProperty ;
          rdfs:domain bto:Patient ;
          rdfs:range rdf:PlainLiteral ;
          rdfs:comment "An open box for adding notes about the patient."@en ;
          rdfs:label "notes"@en .


###  https://w3id.org/brainteaser/ontology/schema/numberSpinalCordLesions
bto:numberSpinalCordLesions rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:MRI ;
                            rdfs:range xsd:float ;
                            rdfs:comment "The number of spinal cord lesions showed in the MRI."@en ;
                            rdfs:label "numberSpinalCordLesions"@en .


###  https://w3id.org/brainteaser/ontology/schema/oligoclonalBandsNumber
bto:oligoclonalBandsNumber rdf:type owl:DatatypeProperty ,
                                    owl:FunctionalProperty ;
                           rdfs:domain bto:OligoclonalBands ;
                           rdfs:range xsd:integer ;
                           rdfs:comment "The number of oligoclonal bands present in the specimen."@en ;
                           rdfs:label "oligoclonalBandsNumber"@en .


###  https://w3id.org/brainteaser/ontology/schema/oligoclonalBandsPresence
bto:oligoclonalBandsPresence rdf:type owl:DatatypeProperty ,
                                      owl:FunctionalProperty ;
                             rdfs:domain bto:OligoclonalBands ;
                             rdfs:range xsd:boolean ;
                             rdfs:comment "Whether the tested specimen presents oligoclonal bands."@en ;
                             rdfs:label "oligoclonalBandsPresence"@en .


###  https://w3id.org/brainteaser/ontology/schema/oligoclonalBandsType
bto:oligoclonalBandsType rdf:type owl:DatatypeProperty ,
                                  owl:FunctionalProperty ;
                         rdfs:domain bto:OligoclonalBands ;
                         rdfs:range [ rdf:type rdfs:Datatype ;
                                      owl:oneOf [ rdf:type rdf:List ;
                                                  rdf:first "in CSF" ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "in CSF & serum" ;
                                                             rdf:rest rdf:nil
                                                           ]
                                                ]
                                    ] ;
                         rdfs:comment "Whether the oligoclonal bands were found in CSF or in CSF & serum."@en ;
                         rdfs:label "oligoclonalBandsType"@en .


###  https://w3id.org/brainteaser/ontology/schema/onsetElapsedTime
bto:onsetElapsedTime rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:BeforeOnset ;
                     rdfs:range [ rdf:type rdfs:Datatype ;
                                  owl:oneOf [ rdf:type rdf:List ;
                                              rdf:first "beyond 5years" ;
                                              rdf:rest [ rdf:type rdf:List ;
                                                         rdf:first "within 5 yeras" ;
                                                         rdf:rest rdf:nil
                                                       ]
                                            ]
                                ] ;
                     rdfs:comment "The time elapsed since the occurrence of an event that happened before the onset."@en ;
                     rdfs:label "onsetElapsedTime"@en .


###  https://w3id.org/brainteaser/ontology/schema/originalALSFRS
bto:originalALSFRS rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:ALSFRS ;
                   rdfs:range xsd:integer ;
                   rdfs:comment "Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items: 1,2,3,4,5,6,7,8,9 and old10."@en ;
                   rdfs:label "originalALSFRS"@en .


###  https://w3id.org/brainteaser/ontology/schema/otherFactorsAffectedHandTrial
bto:otherFactorsAffectedHandTrial rdf:type owl:DatatypeProperty ;
                                  rdfs:domain bto:HandDexterity ;
                                  rdfs:range rdf:PlainLiteral ;
                                  rdfs:comment "Other factors that affected the hand dextricity test."@en ;
                                  rdfs:label "otherFactorsAffectedHandTrial"@en .


###  https://w3id.org/brainteaser/ontology/schema/otherOnset
bto:otherOnset rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:Onset ;
               rdfs:range [ rdf:type rdfs:Datatype ;
                            owl:unionOf ( rdf:PlainLiteral
                                          xsd:boolean
                                        )
                          ] ;
               rdfs:comment "Other symptoms experienced by the patient during onset."@en ;
               rdfs:label "otherOnset"@en .


###  https://w3id.org/brainteaser/ontology/schema/otherRelapse
bto:otherRelapse rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:Relapse ;
                 rdfs:range rdf:PlainLiteral ;
                 rdfs:comment "Other functional systems involved in the relapse."@en ;
                 rdfs:label "otherRelapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/outsideWalkingStatus
bto:outsideWalkingStatus rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:ClinicalEvaluation ;
                         rdfs:range [ rdf:type rdfs:Datatype ;
                                      owl:oneOf [ rdf:type rdf:List ;
                                                  rdf:first "Crutches"@en ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "Fully ambulatory"@en ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "Orthosis"@en ;
                                                                        rdf:rest [ rdf:type rdf:List ;
                                                                                   rdf:first "Walker"@em ;
                                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                                              rdf:first "Walking stick"@en ;
                                                                                              rdf:rest [ rdf:type rdf:List ;
                                                                                                         rdf:first "Wheelchair"@en ;
                                                                                                         rdf:rest rdf:nil
                                                                                                       ]
                                                                                            ]
                                                                                 ]
                                                                      ]
                                                           ]
                                                ]
                                    ] ;
                         rdfs:comment "The ambulatory status of the patient when walking outside. (e.g., whether they walk on their own or they need assistive devices)"@en ;
                         rdfs:label "outsideWalkingStatus"@en .


###  https://w3id.org/brainteaser/ontology/schema/packYear
bto:packYear rdf:type owl:DatatypeProperty ,
                      owl:FunctionalProperty ;
             rdfs:domain bto:Smoking ;
             rdfs:range xsd:float ;
             rdfs:comment "Quantificator of lifetime tobacco exposure defined as: (number of cigarettes smoked per day) X (number of years smoked)/20."@en ;
             rdfs:label "packYear"@en .


###  https://w3id.org/brainteaser/ontology/schema/participationEnd
bto:participationEnd rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:ClinicalTrialParticipation ;
                     rdfs:range xsd:date ;
                     rdfs:comment "The calendar date of the end of subject's partiicpation in a clinical trial."@en ;
                     rdfs:label "participationEnd"@en .


###  https://w3id.org/brainteaser/ontology/schema/participationStart
bto:participationStart rdf:type owl:DatatypeProperty ,
                                owl:FunctionalProperty ;
                       rdfs:domain bto:ClinicalTrialParticipation ;
                       rdfs:range xsd:date ;
                       rdfs:comment "The calendar date of the start of subject's partiicpation in a clinical trial."@en ;
                       rdfs:label "participationStart"@en .


###  https://w3id.org/brainteaser/ontology/schema/pathologicalJCCSF
bto:pathologicalJCCSF rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:CSFAnalysis ;
                      rdfs:range xsd:boolean ;
                      rdfs:comment "Whether the JC virus detected in the CSF specimen is pathological."@en ;
                      rdfs:label "pathologicalJCCSF"@en ;
                      skos:note "This data property can only be populated in \"visuJCTestedCSF\" has value True."@en .


###  https://w3id.org/brainteaser/ontology/schema/pelvicSurgery
bto:pelvicSurgery rdf:type owl:DatatypeProperty ;
                  rdfs:domain [ rdf:type owl:Class ;
                                owl:unionOf ( bto:Last5YearsEvent
                                              bto:MoreThan5YearsEvent
                                            )
                              ] ;
                  rdfs:range xsd:boolean ;
                  rdfs:comment "Whether a patient had a pelivc surgery."@en ;
                  rdfs:label "pelvicSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/phenotype
bto:phenotype rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:Patient ;
              rdfs:range rdf:PlainLiteral ;
              dcterms:conformsTo UMLS:C4086242 ;
              rdfs:comment "The observable properties present during a disease. [Definition Source: NCI]"@en ;
              rdfs:isDefinedBy NCIT:C125204 ;
              rdfs:label "phenotype"@en .


###  https://w3id.org/brainteaser/ontology/schema/placeArea
bto:placeArea rdf:type owl:DatatypeProperty ;
              rdfs:domain bto:Place ;
              rdfs:range [ rdf:type rdfs:Datatype ;
                           owl:oneOf [ rdf:type rdf:List ;
                                       rdf:first "city" ;
                                       rdf:rest [ rdf:type rdf:List ;
                                                  rdf:first "rural" ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "town" ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "urban" ;
                                                                        rdf:rest rdf:nil
                                                                      ]
                                                           ]
                                                ]
                                     ]
                         ] ;
              rdfs:comment "The type of populated area that better describe the place."@en ;
              rdfs:label "placeArea"@en .


###  https://w3id.org/brainteaser/ontology/schema/positivityResult
bto:positivityResult rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:LaboratoryTestResult ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether the laboratory test result was positive or not."@en ;
                     rdfs:label "positivityResult"@en ;
                     skos:note "This data property is only populated for positive/negative laboratory test result."@en .


###  https://w3id.org/brainteaser/ontology/schema/predominantLimbsImpairment
bto:predominantLimbsImpairment rdf:type owl:DatatypeProperty ,
                                        owl:FunctionalProperty ;
                               rdfs:domain bto:ClinicalEvaluation ;
                               rdfs:range [ rdf:type rdfs:Datatype ;
                                            owl:oneOf [ rdf:type rdf:List ;
                                                        rdf:first "both" ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "distal" ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "proximal" ;
                                                                              rdf:rest rdf:nil
                                                                            ]
                                                                 ]
                                                      ]
                                          ] ;
                               rdfs:comment "Whether the patient predominantly presents distal limbs impairment or proximal limbs impairment."@en ;
                               rdfs:label "predominantLimbsImpairment"@en ;
                               skos:note "This data property is used only for ALS patients."@en .


###  https://w3id.org/brainteaser/ontology/schema/predominantLimbsSide
bto:predominantLimbsSide rdf:type owl:DatatypeProperty ,
                                  owl:FunctionalProperty ;
                         rdfs:domain bto:ClinicalEvaluation ;
                         rdfs:range [ rdf:type rdfs:Datatype ;
                                      owl:oneOf [ rdf:type rdf:List ;
                                                  rdf:first "left" ;
                                                  rdf:rest [ rdf:type rdf:List ;
                                                             rdf:first "right" ;
                                                             rdf:rest [ rdf:type rdf:List ;
                                                                        rdf:first "symmetric" ;
                                                                        rdf:rest rdf:nil
                                                                      ]
                                                           ]
                                                ]
                                    ] ;
                         rdfs:comment "The side of the body that predominantly presents limb impariment."@en ;
                         rdfs:label "predominantLimbsSide"@en ;
                         skos:note "This data property is used only for ALS patients."@en .


###  https://w3id.org/brainteaser/ontology/schema/predominantMotorNeuron
bto:predominantMotorNeuron rdf:type owl:DatatypeProperty ,
                                    owl:FunctionalProperty ;
                           rdfs:domain bto:ClinicalEvaluation ;
                           rdfs:range [ rdf:type rdfs:Datatype ;
                                        owl:oneOf [ rdf:type rdf:List ;
                                                    rdf:first "both motor neuron" ;
                                                    rdf:rest [ rdf:type rdf:List ;
                                                               rdf:first "lower motor neuron" ;
                                                               rdf:rest [ rdf:type rdf:List ;
                                                                          rdf:first "upper motor neuron" ;
                                                                          rdf:rest rdf:nil
                                                                        ]
                                                             ]
                                                  ]
                                      ] ;
                           rdfs:comment "Whether the patient presents a predominance of lower motor neuron, upper motor neuron or both."@en ;
                           rdfs:label "predominantMotorNeuron"@en ;
                           skos:note "This data property is used only for ALS patients."@en .


###  https://w3id.org/brainteaser/ontology/schema/pregnancyComplications
bto:pregnancyComplications rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:Pregnancy ;
                           rdfs:range rdf:PlainLiteral ;
                           rdfs:comment "Any kind of complication related to the pregnancy."@en ;
                           rdfs:label "pregnancyComplications"@en .


###  https://w3id.org/brainteaser/ontology/schema/pregnancyEnd
bto:pregnancyEnd rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:Pregnancy ;
                 rdfs:range xsd:date ;
                 rdfs:comment "The calendar date in which the pregnancy ended."@en ;
                 rdfs:label "pregnancyEnd"@en .


###  https://w3id.org/brainteaser/ontology/schema/pregnancyEndEvent
bto:pregnancyEndEvent rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:Pregnancy ;
                      rdfs:range rdf:PlainLiteral ;
                      rdfs:comment "The event that ended the pregnancy."@en ;
                      rdfs:label "pregnancyEndEvent"@en .


###  https://w3id.org/brainteaser/ontology/schema/pregnancyStart
bto:pregnancyStart rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:Pregnancy ;
                   rdfs:range xsd:date ;
                   rdfs:comment "The calendar date in which the pregnancy started."@en ;
                   rdfs:label "pregnancyStart"@en .


###  https://w3id.org/brainteaser/ontology/schema/primaryNeoplasm
bto:primaryNeoplasm rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:ALSBrainteaserComorbidities ;
                    rdfs:range xsd:boolean ;
                    rdfs:comment "Whether a patient ever had a primary neoplasm."@en ;
                    rdfs:label "primaryNeoplasm"@en .


###  https://w3id.org/brainteaser/ontology/schema/privacyPreservingDate
bto:privacyPreservingDate rdf:type owl:DatatypeProperty ;
                          rdfs:domain [ rdf:type owl:Class ;
                                        owl:unionOf ( <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration>
                                                      bto:Activity
                                                      bto:AppQuestionnaire
                                                      bto:Condition
                                                      bto:Event
                                                      bto:InterventionOrProcedure
                                                      bto:Pregnancy
                                                      bto:Relapse
                                                      bto:Trauma
                                                      bto:WeatherData
                                                    )
                                      ] ;
                          rdfs:range xsd:float ;
                          rdfs:comment "Privacy preserving date computed according to an algorithm used to extract public instances."@en ;
                          rdfs:label "privacyPreservingDate"@en .


###  https://w3id.org/brainteaser/ontology/schema/privacyPreservingDeathDate
bto:privacyPreservingDeathDate rdf:type owl:DatatypeProperty ,
                                        owl:FunctionalProperty ;
                               rdfs:domain bto:Patient ;
                               rdfs:range xsd:float ;
                               rdfs:comment "Privacy preserving death date computed according to an algorithm used to extract public instances."@en ;
                               rdfs:label "privacyPreservingDeathDate"@en .


###  https://w3id.org/brainteaser/ontology/schema/procedureEnd
bto:procedureEnd rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:InterventionOrProcedure ;
                 rdfs:range xsd:date ;
                 rdfs:comment "The calendar date of the end of an intervention or procedure."@en ;
                 rdfs:label "procedureEnd"@en .


###  https://w3id.org/brainteaser/ontology/schema/procedureStart
bto:procedureStart rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:InterventionOrProcedure ;
                   rdfs:range xsd:date ;
                   rdfs:comment "The calendar start of an intervention or procedure."@en ;
                   rdfs:label "procedureStart"@en .


###  https://w3id.org/brainteaser/ontology/schema/proteinsCSF
bto:proteinsCSF rdf:type owl:DatatypeProperty ,
                         owl:FunctionalProperty ;
                rdfs:domain bto:CSFAnalysis ;
                rdfs:range xsd:float ;
                rdfs:comment "A quantitative measurement of proteins present in a sample of CSF [ mg/l]."@en ;
                rdfs:label "proteinsCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryAOPAbs
bto:pulmonaryAOPAbs rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:PulmonaryFunctionTest ;
                    rdfs:range xsd:float ;
                    rdfs:comment "Occlusion pressure at 100 ms (P0.1) is defined as the negative pressure measured 100 ms after the initiation of an inspiratory effort performed against a closed respiratory circuit. [Definition Source: Beloncle, F., Piquilloud, L., Olivier, PY. et al. Accuracy of P0.1 measurements performed by ICU ventilators: a bench study. Ann. Intensive Care 9, 104 (2019)]"@en ;
                    rdfs:label "pulmonaryAOPAbs"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryFEV6
bto:pulmonaryFEV6 rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:PulmonaryFunctionTest ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Forced expiratory volume (FEV) is the amount of air expired in six seconds of the FVC test. [Definition Source: John Hopkins Medicine]"@en ;
                  rdfs:label "pulmonaryFEV6"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryFVCLyingDown
bto:pulmonaryFVCLyingDown rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:PulmonaryFunctionTest ;
                          rdfs:range xsd:float ;
                          rdfs:comment "Forced Vital Capacity (FVC) when patient is lied down."@en ;
                          rdfs:label "pulmonaryFVCLyingDown"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryFVCLyingDownPercentage
bto:pulmonaryFVCLyingDownPercentage rdf:type owl:DatatypeProperty ;
                                    rdfs:domain bto:PulmonaryFunctionTest ;
                                    rdfs:range xsd:float ;
                                    rdfs:comment "Percentage of FVC lying down."@en ;
                                    rdfs:label "pulmonaryFVCLyingDownPercentage"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryFVCRel
bto:pulmonaryFVCRel rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:PulmonaryFunctionTest ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The percentage of Forced vital capacity (FVC)  is the amount of air exhaled forcefully and quickly after inhaling as much as you can. [Defintion Source: John Hopkins Medicine]"@en ;
                    rdfs:label "pulmonaryFVCRel"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryFVCSitting
bto:pulmonaryFVCSitting rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:PulmonaryFunctionTest ;
                        rdfs:range xsd:float ;
                        rdfs:comment "Forced Vital Capacity (FVC) when patient is sitted."@en ;
                        rdfs:label "pulmonaryFVCSitting"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryFVCSittingPercentage
bto:pulmonaryFVCSittingPercentage rdf:type owl:DatatypeProperty ;
                                  rdfs:domain bto:PulmonaryFunctionTest ;
                                  rdfs:range xsd:float ;
                                  rdfs:comment "Percentage of FVC sitting"@en ;
                                  rdfs:label "pulmonaryFVCSittingPercentage"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryMEP
bto:pulmonaryMEP rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:PulmonaryFunctionTest ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Maximum Expiratory Pressure (MEP) is the greatest amount of pressure that can be generated by exhaling against a mouthpiece, which is a measure of the strength of respiratory muscles. [Definition Source: NCI] (uom: CMH2O)"@en ;
                 rdfs:label "pulmonaryMEP"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryMEPAbs
bto:pulmonaryMEPAbs rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:PulmonaryFunctionTest ;
                    rdfs:range xsd:float ;
                    rdfs:comment "Maximum Expiratory Pressure (MEP) is the highest pressure that can be developed during a forceful expiratory effort against an occluded airway. It is usually measured at maximal inspiration and reported as a positive number in either cm H2O or mmHg. [Definition Source: The University of Texas Medical Branch]"@en ;
                    rdfs:label "pulmonaryMEPAbs"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryMEPpercentage
bto:pulmonaryMEPpercentage rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:PulmonaryFunctionTest ;
                           rdfs:range xsd:float ;
                           rdfs:comment "Percentage of MEP."@en ;
                           rdfs:label "pulmonaryMEPpercentage"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryMIP
bto:pulmonaryMIP rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:PulmonaryFunctionTest ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Maximum Inspiratory Pressure (MIP) is the greatest amount of pressure that can be generated during inhalation against a fully occluded airway, which is used to measure the strength of respiratory muscles. [Definition Source: NCI]"@en ;
                 rdfs:label "pulmonaryMIP"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryMIPAbs
bto:pulmonaryMIPAbs rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:PulmonaryFunctionTest ;
                    rdfs:range xsd:float ;
                    rdfs:comment "Maximum Inspiratory Pressure (MIP) is the lowest pressure developed during a forceful inspiration against an occluded airway. It is usually measured at maximal expiration and recorded as a negative number in either cm H2O or mmHg. [Definition Source: The University of Texas Medical Branch]"@en ;
                    rdfs:label "pulmonaryMIPAbs"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryMIPpercentage
bto:pulmonaryMIPpercentage rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:PulmonaryFunctionTest ;
                           rdfs:range xsd:float ;
                           rdfs:comment "Percentage of MIP."@en ;
                           rdfs:label "pulmonaryMIPpercentage"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryNIP
bto:pulmonaryNIP rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:PulmonaryFunctionTest ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Maximal Negative Inspiratory Pressure (NIP) measures the strength of the diaphragm and other muscles of inspiration and reflects the ability to maintain normal lung expansion and avoid atelectasis. [Definition Source: doi.org/10.1016/B978-032304841-5.50067-4 ]"@en ;
                 rdfs:label "pulmonaryNIP"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryPCF
bto:pulmonaryPCF rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:PulmonaryFunctionTest ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Peak Cough Flow (PCF) is the maximum rate of air flow expelled through the mouth, endotracheal, or tracheostomy tube during a cough. [Definition Source: NCI]"@en ;
                 rdfs:label "pulmonaryPCF"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryPCO2
bto:pulmonaryPCO2 rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:PulmonaryFunctionTest ;
                  rdfs:range xsd:float ;
                  rdfs:comment "The partial pressure of carbon dioxide (PCO2) is the concentration of carbon dioxide in the blood. This is a sensitive indication of the efficiency or level of ventilation of the lungs. [Definition Source: Collins Dictionary of Medicine]"@en ;
                  rdfs:label "pulmonaryPCO2"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryPO2
bto:pulmonaryPO2 rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:PulmonaryFunctionTest ;
                 rdfs:range xsd:float ;
                 rdfs:comment "The partial pressure of oxigen (PO2) is  the concentration of oxygen in the blood. This commonly measured parameter is an important indicator of the efficiency with which oxygen is transferred from atmosphere to blood. [Definition Source: Collins Dictionary of Medicine]"@en ;
                 rdfs:label "pulmonaryPO2"@en .


###  https://w3id.org/brainteaser/ontology/schema/pulmonaryVCAbs
bto:pulmonaryVCAbs rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:PulmonaryFunctionTest ;
                   rdfs:range xsd:float ;
                   rdfs:comment "Vital capacity (VC) is the total volume of air that can be exhaled after inhaling as much as you can. [Definition Source: John Hopkins Medicine]"@en ;
                   rdfs:label "pulmonaryVCAbs"@en .


###  https://w3id.org/brainteaser/ontology/schema/pyramidalEDSS
bto:pyramidalEDSS rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:EDSS ;
                  rdfs:range xsd:integer ;
                  rdfs:comment "Expanded Disability Status Score (EDSS) score for pyramidal functions."@en ;
                  rdfs:label "pyramidalEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/pyramidalRelapse
bto:pyramidalRelapse rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:Relapse ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether the relapse involved the pyramidal functions."@en ;
                     rdfs:label "pyramidalRelapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/quadraticTrendHeartRate
bto:quadraticTrendHeartRate rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:HeartRateMeasurement ;
                            rdfs:range xsd:float ;
                            rdfs:comment "The parameter corresponding to the curvature of heart rate. "@en ;
                            rdfs:label "quadraticTrendHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/questionnaireSubmitted
bto:questionnaireSubmitted rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:AppQuestionnaire ;
                           rdfs:range xsd:dateTime ;
                           rdfs:comment "When the questionnaire was submitted."@en ;
                           rdfs:label "questionnaireSubmitted"@en .


###  https://w3id.org/brainteaser/ontology/schema/quotientAlbuminCSF
bto:quotientAlbuminCSF rdf:type owl:DatatypeProperty ,
                                owl:FunctionalProperty ;
                       rdfs:domain bto:CSFAnalysis ;
                       rdfs:range xsd:float ;
                       rdfs:comment "CSF/serum albumin ratio is performed to understand the blood–CSF barrier disruption. [Defintion Source: Luque, Francisco A, and Stephen L Jaffe. “Cerebrospinal fluid analysis in multiple sclerosis.” International review of neurobiology vol. 79 (2007)]"@en ;
                       rdfs:label "quotientAlbuminCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/r2HeartRate
bto:r2HeartRate rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:HeartRateMeasurement ;
                rdfs:range xsd:float ;
                rdfs:comment "The quality of the quadratic model."@en ;
                rdfs:label "r2HeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/reasonIrregularCycle
bto:reasonIrregularCycle rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:MenstrualCycle ;
                         rdfs:range rdf:PlainLiteral ;
                         rdfs:comment "Why the patient has an irregular menstrual cycle."@en ;
                         rdfs:label "reasonIrregularCycle"@en .


###  https://w3id.org/brainteaser/ontology/schema/reasonNoMenstrualCycle
bto:reasonNoMenstrualCycle rdf:type owl:DatatypeProperty ;
                           rdfs:domain bto:MenstrualCycle ;
                           rdfs:range rdf:PlainLiteral ;
                           rdfs:comment "Why the patient has no menstrual cycle. (e.g., menopause)"@en ;
                           rdfs:label "reasonNoMenstrualCycle"@en .


###  https://w3id.org/brainteaser/ontology/schema/reasonWalkTestNotCompleted
bto:reasonWalkTestNotCompleted rdf:type owl:DatatypeProperty ;
                               rdfs:domain bto:WalkTest ;
                               rdfs:range rdf:PlainLiteral ;
                               rdfs:comment "The reason the walk test was not completed."@en ;
                               rdfs:label "reasonWalkTestNotCompleted"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseClinicalTherapy
bto:relapseClinicalTherapy rdf:type owl:DatatypeProperty ,
                                    owl:FunctionalProperty ;
                           rdfs:domain bto:Relapse ;
                           rdfs:range xsd:boolean ;
                           rdfs:comment "Whether the relapse required treatment in an ambulatory care clinic."@en ;
                           rdfs:label "relapseClinicalTherapy"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseCortisoneTherapy
bto:relapseCortisoneTherapy rdf:type owl:DatatypeProperty ,
                                     owl:FunctionalProperty ;
                            rdfs:domain bto:Relapse ;
                            rdfs:range xsd:boolean ;
                            rdfs:comment "Whether the relapse required a cortisone therapy."@en ;
                            rdfs:label "relapseCortisoneTherapy"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseDuration
bto:relapseDuration rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:Relapse ;
                    rdfs:range xsd:integer ;
                    rdfs:comment "The number of days the relapse lasted."@en ;
                    rdfs:label "relapseDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseEnd
bto:relapseEnd rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:Relapse ;
               rdfs:range xsd:date ;
               rdfs:comment "The calendar date of the end of the relapse."@en ;
               rdfs:label "relapseEnd"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseHospitalAdmission
bto:relapseHospitalAdmission rdf:type owl:DatatypeProperty ,
                                      owl:FunctionalProperty ;
                             rdfs:domain bto:Relapse ;
                             rdfs:range xsd:boolean ;
                             rdfs:comment "Whether the relapse required an hospital admission."@en ;
                             rdfs:label "relapseHospitalAdmission"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseImpactOnADL
bto:relapseImpactOnADL rdf:type owl:DatatypeProperty ,
                                owl:FunctionalProperty ;
                       rdfs:domain bto:Relapse ;
                       rdfs:range xsd:boolean ;
                       rdfs:comment "Whether the relapse afftecd the Activity of Daily Living (ADL)."@en ;
                       rdfs:label "relapseImpactOnADL"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseRecovery
bto:relapseRecovery rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:Relapse ;
                    rdfs:range [ rdf:type rdfs:Datatype ;
                                 owl:oneOf [ rdf:type rdf:List ;
                                             rdf:first "complete" ;
                                             rdf:rest [ rdf:type rdf:List ;
                                                        rdf:first "none" ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "partial" ;
                                                                   rdf:rest rdf:nil
                                                                 ]
                                                      ]
                                           ]
                               ] ;
                    rdfs:comment "How much the patient recovered from the relapse."@en ;
                    rdfs:label "relapseRecovery"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseSequela
bto:relapseSequela rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:Relapse ;
                   rdfs:range xsd:boolean ;
                   rdfs:comment "Whether the patient presented symptoms continuing in time, maybe less severe."@en ;
                   rdfs:label "relapseSequela"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseSeverity
bto:relapseSeverity rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:Relapse ;
                    rdfs:range [ rdf:type rdfs:Datatype ;
                                 owl:oneOf [ rdf:type rdf:List ;
                                             rdf:first "life risk" ;
                                             rdf:rest [ rdf:type rdf:List ;
                                                        rdf:first "moderate" ;
                                                        rdf:rest [ rdf:type rdf:List ;
                                                                   rdf:first "serious" ;
                                                                   rdf:rest [ rdf:type rdf:List ;
                                                                              rdf:first "slight" ;
                                                                              rdf:rest rdf:nil
                                                                            ]
                                                                 ]
                                                      ]
                                           ]
                               ] ;
                    rdfs:comment "The severity of the relapse."@en ;
                    rdfs:label "relapseSeverity"@en .


###  https://w3id.org/brainteaser/ontology/schema/relapseStart
bto:relapseStart rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:Relapse ;
                 rdfs:range xsd:date ;
                 rdfs:comment "The calendar date of the start of the relapse."@en ;
                 rdfs:label "relapseStart"@en .


###  https://w3id.org/brainteaser/ontology/schema/relativeEndDate
bto:relativeEndDate rdf:type owl:DatatypeProperty ,
                             owl:FunctionalProperty ;
                    rdfs:domain bto:Activity ;
                    rdfs:range xsd:gYear ;
                    rdfs:comment "Privacy preserving end date computed according to an algorithm used to extract public instances."@en ;
                    rdfs:label "relativeEndDate"@en .


###  https://w3id.org/brainteaser/ontology/schema/relativeStartDate
bto:relativeStartDate rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:Activity ;
                      rdfs:range xsd:gYear ;
                      rdfs:comment "Privacy preserving start date computed according to an algorithm used to extract public instances."@en ;
                      rdfs:label "relativeStartDate"@en .


###  https://w3id.org/brainteaser/ontology/schema/remSleep
bto:remSleep rdf:type owl:DatatypeProperty ;
             rdfs:domain bto:SleepData ;
             rdfs:range xsd:float ;
             rdfs:comment "REM sleep duration registered by the wearable device. [uom: seconds]"@en ;
             rdfs:label "remSleep"@en .


###  https://w3id.org/brainteaser/ontology/schema/repirationSampEn
bto:repirationSampEn rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:RespiratoryData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The sample entropy"@en ;
                     rdfs:label "repirationSampEn"@en .


###  https://w3id.org/brainteaser/ontology/schema/residenceEnd
bto:residenceEnd rdf:type owl:DatatypeProperty ,
                          owl:FunctionalProperty ;
                 rdfs:domain bto:Residence ;
                 rdfs:range xsd:gYear ;
                 rdfs:comment "The calendar end date of the patient's residence in a specific geographical location."@en ;
                 rdfs:label "residenceEnd"@en .


###  https://w3id.org/brainteaser/ontology/schema/residenceStart
bto:residenceStart rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:Residence ;
                   rdfs:range xsd:gYear ;
                   rdfs:comment "The calendar start date of the patient's residence in a specific geographical location."@en ;
                   rdfs:label "residenceStart"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationAlpha1DimMean
bto:respirationAlpha1DimMean rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:RespiratoryData ;
                             rdfs:range xsd:float ;
                             rdfs:comment "Multifractal DFA. DimMean is the mean of singularity dimensions."@en ;
                             rdfs:label "respirationAlpha1DimMean"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationAlpha1DimRange
bto:respirationAlpha1DimRange rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:RespiratoryData ;
                              rdfs:range xsd:float ;
                              rdfs:comment "Multifractal DFA. DimRange is the range of singularity dimensions, corresponding to the height of the singularity spectrum."@en ;
                              rdfs:label "respirationAlpha1DimRange"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationAlpha1ExpMean
bto:respirationAlpha1ExpMean rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:RespiratoryData ;
                             rdfs:range xsd:float ;
                             rdfs:comment "Multifractal DFA of short-term fluctuations. ExpMean is the mean of singularity exponents."@en ;
                             rdfs:label "respirationAlpha1ExpMean"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationAlpha1ExpRange
bto:respirationAlpha1ExpRange rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:RespiratoryData ;
                              rdfs:range xsd:float ;
                              rdfs:comment "Multifractal DFA of short-term fluctuations. ExpRange is the range of singularity exponents, corresponding to the width of the singularity spectrum. "@en ;
                              rdfs:label "respirationAlpha1ExpRange"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationAlpha2DimMean
bto:respirationAlpha2DimMean rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:RespiratoryData ;
                             rdfs:range xsd:float ;
                             rdfs:comment "Multifractal DFA. Dimmean is the mean of singularity dimensions."@en ;
                             rdfs:label "respirationAlpha2DimMean"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationAlpha2DimRange
bto:respirationAlpha2DimRange rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:RespiratoryData ;
                              rdfs:range xsd:float ;
                              rdfs:comment "Multifractal DFA. DimRange is the range of singularity dimensions, corresponding to the height of the singularity spectrum."@en ;
                              rdfs:label "respirationAlpha2DimRange"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationAlpha2ExpMean
bto:respirationAlpha2ExpMean rdf:type owl:DatatypeProperty ;
                             rdfs:domain bto:RespiratoryData ;
                             rdfs:range xsd:float ;
                             rdfs:comment "Multifractal DFA of long-term fluctuations. ExpMean is the mean of singularity exponents."@en ;
                             rdfs:label "respirationAlpha2ExpMean"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationAlpha2ExpRange
bto:respirationAlpha2ExpRange rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:RespiratoryData ;
                              rdfs:range xsd:float ;
                              rdfs:comment "Multifractal DFA of long-term fluctuations. ExpRange is the range of singularity exponents, corresponding to the width of the singularity spectrum. "@en ;
                              rdfs:label "respirationAlpha2ExpRange"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationApEn
bto:respirationApEn rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:RespiratoryData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The approximate entropy "@en ;
                    rdfs:label "respirationApEn"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationDFAalpha1
bto:respirationDFAalpha1 rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:RespiratoryData ;
                         rdfs:range xsd:float ;
                         rdfs:comment "The “short-term” fluctuation value generated from Detrended Fluctuation Analysis i.e. the root mean square deviation from the fitted trend of the breath-to-breath intervals. Will only be computed if there are more than 160 breath cycles in the respiratory rate. "@en ;
                         rdfs:label "respirationDFAalpha1"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationDFAalpha2
bto:respirationDFAalpha2 rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:RespiratoryData ;
                         rdfs:range xsd:float ;
                         rdfs:comment "The long-term fluctuation value. Will only be computed if there are more than 640 breath cycles in the respiratory rate."@en ;
                         rdfs:label "respirationDFAalpha2"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationRMSSD
bto:respirationRMSSD rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:RespiratoryData ;
                     rdfs:range xsd:float ;
                     rdfs:comment "The root mean square of successive differences of the breath-to-breath intervals."@en ;
                     rdfs:label "respirationRMSSD"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationSD1
bto:respirationSD1 rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:RespiratoryData ;
                   rdfs:range xsd:float ;
                   rdfs:comment "A measure of the spread of breath-to-breath intervals on the Poincaré plot perpendicular to the line of identity. It is an index of short-term variability."@en ;
                   rdfs:label "respirationSD1"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationSD2
bto:respirationSD2 rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:RespiratoryData ;
                   rdfs:range xsd:float ;
                   rdfs:comment "SD2 is a measure of the spread of breath-to-breath intervals on the Poincaré plot along the line of identity. It is an index of long-term variability."@en ;
                   rdfs:label "respirationSD2"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationSD2SD1
bto:respirationSD2SD1 rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:RespiratoryData ;
                      rdfs:range xsd:float ;
                      rdfs:comment "The ratio between short- and long-term fluctuations of the breath-to-breath intervals (SD2 divided by SD1). "@en ;
                      rdfs:label "respirationSD2SD1"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationSDBB
bto:respirationSDBB rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:RespiratoryData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The standard deviation of the breath-to-breath intervals. "@en ;
                    rdfs:label "respirationSDBB"@en .


###  https://w3id.org/brainteaser/ontology/schema/respirationSDSD
bto:respirationSDSD rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:RespiratoryData ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The standard deviation of the successive differences between adjacent"@en ;
                    rdfs:label "respirationSDSD"@en .


###  https://w3id.org/brainteaser/ontology/schema/respiratorySubscore
bto:respiratorySubscore rdf:type owl:DatatypeProperty ,
                                 owl:FunctionalProperty ;
                        rdfs:domain bto:ALSFRS ;
                        rdfs:range xsd:integer ;
                        rdfs:comment "Respiratory ALSFRS subscore. Sum of items: 10, 11 and 12."@en ;
                        rdfs:label "respiratorySubscore"@en .


###  https://w3id.org/brainteaser/ontology/schema/restStressDuration
bto:restStressDuration rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:StressLevel ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Rest stress duration registered by the wearable device. [uom: seconds]"@en ;
                       rdfs:label "restStressDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/restingHeartRate
bto:restingHeartRate rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:HeartRateMeasurement ;
                     rdfs:range xsd:float ;
                     rdfs:comment "Resting heart rate registered by the wearable device. [uom: bpm]"@en ;
                     rdfs:label "restingHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/retiredAtDiagnosis
bto:retiredAtDiagnosis rdf:type owl:DatatypeProperty ,
                                owl:FunctionalProperty ;
                       rdfs:domain bto:Patient ;
                       rdfs:range xsd:boolean ;
                       rdfs:comment "An indicator of whether the patient was retired at the time of diagnosis."@en ;
                       rdfs:label "retiredAtDiagnosis"@en .


###  https://w3id.org/brainteaser/ontology/schema/revisedALSFRS
bto:revisedALSFRS rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:ALSFRS ;
                  rdfs:range xsd:integer ;
                  dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C4296567"@en ;
                  rdfs:comment "Revised Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12."@en ;
                  rdfs:isDefinedBy "http://purl.bioontology.org/ontology/SNOMEDCT/718646004" ;
                  rdfs:label "revisedALSFRS" .


###  https://w3id.org/brainteaser/ontology/schema/sdmtCorrect
bto:sdmtCorrect rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:SDMT ;
                rdfs:range xsd:integer ;
                rdfs:comment "Symbol Digital Modalities Test corrected."@en ;
                rdfs:label "sdmtCorrect"@en .


###  https://w3id.org/brainteaser/ontology/schema/sdmtIncorrect
bto:sdmtIncorrect rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:SDMT ;
                  rdfs:range xsd:integer ;
                  rdfs:comment "Symbol Digital Modalities Test raw score."@en ;
                  rdfs:label "sdmtIncorrect"@en .


###  https://w3id.org/brainteaser/ontology/schema/sensoryEDSS
bto:sensoryEDSS rdf:type owl:DatatypeProperty ,
                         owl:FunctionalProperty ;
                rdfs:domain bto:EDSS ;
                rdfs:range xsd:integer ;
                rdfs:comment "Expanded Disability Status Score (EDSS) score for sensory functions."@en ;
                rdfs:label "sensoryEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/sensoryRelapse
bto:sensoryRelapse rdf:type owl:DatatypeProperty ,
                            owl:FunctionalProperty ;
                   rdfs:domain bto:Relapse ;
                   rdfs:range xsd:boolean ;
                   rdfs:comment "Whether the relapse involved sensory functions."@en ;
                   rdfs:label "sensoryRelapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/sex
bto:sex rdf:type owl:DatatypeProperty ,
                 owl:FunctionalProperty ;
        rdfs:domain <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
        rdfs:range [ rdf:type rdfs:Datatype ;
                     owl:oneOf [ rdf:type rdf:List ;
                                 rdf:first "female" ;
                                 rdf:rest [ rdf:type rdf:List ;
                                            rdf:first "male" ;
                                            rdf:rest rdf:nil
                                          ]
                               ]
                   ] ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1522384" ;
        rdfs:comment "The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. [Definition Source: NCI]"@en ;
        rdfs:label "sex"@en .


###  https://w3id.org/brainteaser/ontology/schema/sexuality
bto:sexuality rdf:type owl:DatatypeProperty ,
                       owl:FunctionalProperty ;
              rdfs:domain bto:Lifestyle ;
              rdfs:range rdf:PlainLiteral ;
              dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0036915" ;
              rdfs:comment "The feeling an individual has about their own sexual preferences and how those views are acted upon. [Definition Source: NCI]"@en ;
              rdfs:label "sexuality"@en .


###  https://w3id.org/brainteaser/ontology/schema/slope
bto:slope rdf:type owl:DatatypeProperty ;
          rdfs:domain bto:Patient ;
          rdfs:range xsd:float ;
          rdfs:comment "The slope of the ALSFRS-R score between time-of-onset and Time 0 computed as: (48-ALSFRSR(Time0))/(Time0-TimeOnset)"@en ;
          rdfs:label "slope"@en .


###  https://w3id.org/brainteaser/ontology/schema/smokersNumber
bto:smokersNumber rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:Smoking ;
                  rdfs:range xsd:int ;
                  rdfs:comment "The number of smokers the patient lives or works with."@en ;
                  rdfs:label "smokersNumber"@en .


###  https://w3id.org/brainteaser/ontology/schema/smokingExpositionType
bto:smokingExpositionType rdf:type owl:DatatypeProperty ;
                          rdfs:domain bto:Smoking ;
                          rdfs:range [ rdf:type rdfs:Datatype ;
                                       owl:oneOf [ rdf:type rdf:List ;
                                                   rdf:first "Living with smokers"@en ;
                                                   rdf:rest [ rdf:type rdf:List ;
                                                              rdf:first "Smoker"@en ;
                                                              rdf:rest [ rdf:type rdf:List ;
                                                                         rdf:first "Working with smokers"@en ;
                                                                         rdf:rest rdf:nil
                                                                       ]
                                                            ]
                                                 ]
                                     ] ;
                          rdfs:comment "Type of smoking exposition."@en ;
                          rdfs:label "smokingExpositionType"@en .


###  https://w3id.org/brainteaser/ontology/schema/spinalCordLesions
bto:spinalCordLesions rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:MRI ;
                      rdfs:range xsd:boolean ;
                      rdfs:comment "Whether the MRI showed spinal cord lesions."@en ;
                      rdfs:label "spinalCordLesions"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2AOD100
bto:spo2AOD100 rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SPO2Data ;
               rdfs:range xsd:float ;
               rdfs:comment "Cumulative area of desaturations under the 100% SpO2 level as baseline and normalized by the total recording time"@en ;
               rdfs:label "spo2AOD100"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2AODMax
bto:spo2AODMax rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:SPO2Data ;
               rdfs:range xsd:float ;
               rdfs:comment "The area under the oxygen desaturation event curve, using the maximum SpO2 value as baseline and normalized by the total recording time"@en ;
               rdfs:label "spo2AODMax"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2AV
bto:spo2AV rdf:type owl:DatatypeProperty ;
           rdfs:domain bto:SPO2Data ;
           rdfs:range xsd:float ;
           rdfs:comment "Average of the pulse oximetry."@en ;
           rdfs:label "spo2AV"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2CA
bto:spo2CA rdf:type owl:DatatypeProperty ;
           rdfs:domain bto:SPO2Data ;
           rdfs:range xsd:float ;
           rdfs:comment "Integral SpO2 below the 90% SpO2 level normalized by the total recording time"@en ;
           rdfs:label "spo2CA"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2CT
bto:spo2CT rdf:type owl:DatatypeProperty ;
           rdfs:domain bto:SPO2Data ;
           rdfs:range xsd:float ;
           rdfs:comment "Percentage of the time spent below the 90% oxygen saturation level."@en ;
           rdfs:label "spo2CT"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2DI
bto:spo2DI rdf:type owl:DatatypeProperty ;
           rdfs:domain bto:SPO2Data ;
           rdfs:range xsd:float ;
           rdfs:comment "Delta Index."@en ;
           rdfs:label "spo2DI"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2M
bto:spo2M rdf:type owl:DatatypeProperty ;
          rdfs:domain bto:SPO2Data ;
          rdfs:range xsd:float ;
          rdfs:comment "Percentage of the pulse oximetry 90% below median oxygen saturation."@en ;
          rdfs:label "spo2M"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2MED
bto:spo2MED rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:SPO2Data ;
            rdfs:range xsd:float ;
            rdfs:comment "Median of the pulse oximetry. "@en ;
            rdfs:label "spo2MED"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2Min
bto:spo2Min rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:SPO2Data ;
            rdfs:range xsd:float ;
            rdfs:comment "Minimum value of the pulse oximetry."@en ;
            rdfs:label "spo2Min"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2ODI
bto:spo2ODI rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:SPO2Data ;
            rdfs:range xsd:float ;
            rdfs:comment "The average number of desaturation events per hour (int). "@en ;
            rdfs:label "spo2ODI"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2P
bto:spo2P rdf:type owl:DatatypeProperty ;
          rdfs:domain bto:SPO2Data ;
          rdfs:range xsd:float ;
          rdfs:comment "Percentile (90th)"@en ;
          rdfs:label "spo2P"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2POD
bto:spo2POD rdf:type owl:DatatypeProperty ;
            rdfs:domain bto:SPO2Data ;
            rdfs:range xsd:float ;
            rdfs:comment "Percentage of oxygen desaturation events"@en ;
            rdfs:label "spo2POD"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2RG
bto:spo2RG rdf:type owl:DatatypeProperty ;
           rdfs:domain bto:SPO2Data ;
           rdfs:range xsd:float ;
           rdfs:comment "SpO2 range (difference between the max and min value)."@en ;
           rdfs:label "spo2RG"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2SD
bto:spo2SD rdf:type owl:DatatypeProperty ;
           rdfs:domain bto:SPO2Data ;
           rdfs:range xsd:float ;
           rdfs:comment "Standard deviation of the pulse oximetry."@en ;
           rdfs:label "spo2SD"@en .


###  https://w3id.org/brainteaser/ontology/schema/spo2ZC
bto:spo2ZC rdf:type owl:DatatypeProperty ;
           rdfs:domain bto:SPO2Data ;
           rdfs:range xsd:float ;
           rdfs:comment "Number of zero-crossing points."@en ;
           rdfs:label "spo2ZC"@en .


###  https://w3id.org/brainteaser/ontology/schema/stdHeartRate
bto:stdHeartRate rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:HeartRateMeasurement ;
                 rdfs:range xsd:float ;
                 rdfs:comment "The standard deviation of the heart rate after stimulus onset."@en ;
                 rdfs:label "stdHeartRate"@en .


###  https://w3id.org/brainteaser/ontology/schema/steps12am6am
bto:steps12am6am rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:PhysicalActivityData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Total steps within the considered segment of data and between 12 AM and 6 AM daily"@en ;
                 rdfs:label "steps12am6am"@en .


###  https://w3id.org/brainteaser/ontology/schema/steps12pm6pm
bto:steps12pm6pm rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:PhysicalActivityData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Total steps within the considered segment of data and between 12 PM and 6 PM"@en ;
                 rdfs:label "steps12pm6pm"@en .


###  https://w3id.org/brainteaser/ontology/schema/steps6am12pm
bto:steps6am12pm rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:PhysicalActivityData ;
                 rdfs:range xsd:float ;
                 rdfs:comment "Total steps within the considered segment of data and between 6 AM and 12 PM"@en ;
                 rdfs:label "steps6am12pm"@en .


###  https://w3id.org/brainteaser/ontology/schema/stressDuration
bto:stressDuration rdf:type owl:DatatypeProperty ;
                   rdfs:domain bto:StressLevel ;
                   rdfs:range xsd:float ;
                   rdfs:comment "Stress duration registered by the wearable device. [uom: seconds]"@en ;
                   rdfs:label "stressDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/stressQualifier
bto:stressQualifier rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:StressLevel ;
                    rdfs:range rdf:PlainLiteral ;
                    rdfs:comment "Stress qualifier registered by the wearable device."@en ;
                    rdfs:label "stressQualifier"@en .


###  https://w3id.org/brainteaser/ontology/schema/stroke
bto:stroke rdf:type owl:DatatypeProperty ;
           rdfs:domain bto:ALSBrainteaserComorbidities ;
           rdfs:range xsd:boolean ;
           rdfs:comment "Whether a patient ever had a stroke."@en ;
           rdfs:label "stroke"@en .


###  https://w3id.org/brainteaser/ontology/schema/sunExposure
bto:sunExposure rdf:type owl:DatatypeProperty ,
                         owl:FunctionalProperty ;
                rdfs:domain bto:Lifestyle ;
                rdfs:range xsd:integer ;
                dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1456711" ;
                rdfs:comment "The exposure to incident light from the sun. [Definition Source: NCI]"@en ;
                rdfs:label "sunExposure"@en .


###  https://w3id.org/brainteaser/ontology/schema/symptomClinicalName
bto:symptomClinicalName rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:Symptom ;
                        rdfs:range rdf:PlainLiteral ;
                        rdfs:comment "The clinical name of the symptom."@en ;
                        rdfs:label "symptomClinicalName"@en .


###  https://w3id.org/brainteaser/ontology/schema/symptomEnd
bto:symptomEnd rdf:type owl:DatatypeProperty ;
               rdfs:domain bto:Symptom ;
               rdfs:range xsd:dateTime ;
               rdfs:comment "When the symptom ended."@en ;
               rdfs:label "symptomEnd"@en .


###  https://w3id.org/brainteaser/ontology/schema/symptomGrade
bto:symptomGrade rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:Symptom ;
                 rdfs:range [ rdf:type rdfs:Datatype ;
                              owl:oneOf [ rdf:type rdf:List ;
                                          rdf:first "Mild"@en ;
                                          rdf:rest [ rdf:type rdf:List ;
                                                     rdf:first "Moderate"@en ;
                                                     rdf:rest [ rdf:type rdf:List ;
                                                                rdf:first "Severe"@en ;
                                                                rdf:rest rdf:nil
                                                              ]
                                                   ]
                                        ]
                            ] ;
                 rdfs:comment "The severity of the symptom."@en ;
                 rdfs:label "symptomGrade"@en .


###  https://w3id.org/brainteaser/ontology/schema/symptomStart
bto:symptomStart rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:Symptom ;
                 rdfs:range xsd:dateTime ;
                 rdfs:comment "When the symptom started."@en ;
                 rdfs:label "symptomStart"@en .


###  https://w3id.org/brainteaser/ontology/schema/symptomType
bto:symptomType rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:Symptom ;
                rdfs:range rdf:PlainLiteral ;
                rdfs:comment "Defines the symptom's category."@en ;
                rdfs:label "symptomType"@en .


###  https://w3id.org/brainteaser/ontology/schema/symptomValue
bto:symptomValue rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:Symptom ;
                 rdfs:range xsd:float ;
                 rdfs:comment "The numerical value associated with the symptom, e.g., the temperature fever."@en ;
                 rdfs:label "symptomValue"@en .


###  https://w3id.org/brainteaser/ontology/schema/thoracicSpineSurgery
bto:thoracicSpineSurgery rdf:type owl:DatatypeProperty ;
                         rdfs:domain [ rdf:type owl:Class ;
                                       owl:unionOf ( bto:Last5YearsEvent
                                                     bto:MoreThan5YearsEvent
                                                   )
                                     ] ;
                         rdfs:range xsd:boolean ;
                         rdfs:comment "Whether a patient had a thoracic spine surgery."@en ;
                         rdfs:label "thoracicSpineSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/thoracicSurgery
bto:thoracicSurgery rdf:type owl:DatatypeProperty ;
                    rdfs:domain [ rdf:type owl:Class ;
                                  owl:unionOf ( bto:Last5YearsEvent
                                                bto:MoreThan5YearsEvent
                                              )
                                ] ;
                    rdfs:range xsd:boolean ;
                    rdfs:comment "Whether a patient had a thoracic surgery."@en ;
                    rdfs:label "thoracicSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/thoracicTrauma
bto:thoracicTrauma rdf:type owl:DatatypeProperty ;
                   rdfs:domain [ rdf:type owl:Class ;
                                 owl:unionOf ( bto:Last5YearsEvent
                                               bto:MoreThan5YearsEvent
                                             )
                               ] ;
                   rdfs:range xsd:boolean ;
                   rdfs:comment "Whether a patient had a thoracic trauma."@en ;
                   rdfs:label "thoracicTrauma"@en .


###  https://w3id.org/brainteaser/ontology/schema/thyroidDisorder
bto:thyroidDisorder rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:ALSBrainteaserComorbidities ;
                    rdfs:range xsd:boolean ;
                    rdfs:comment "Whether a patient ever had a thyroid disorder."@en ;
                    rdfs:label "thyroidDisorder"@en .


###  https://w3id.org/brainteaser/ontology/schema/totalCalories
bto:totalCalories rdf:type owl:DatatypeProperty ;
                  rdfs:domain bto:PhysicalActivityData ;
                  rdfs:range xsd:float ;
                  rdfs:comment "Sum of active and basal calories"@en ;
                  rdfs:label "totalCalories"@en .


###  https://w3id.org/brainteaser/ontology/schema/totalLesionsT2MRI
bto:totalLesionsT2MRI rdf:type owl:DatatypeProperty ,
                               owl:FunctionalProperty ;
                      rdfs:domain bto:MRI ;
                      rdfs:range rdf:PlainLiteral ;
                      rdfs:comment "The total number of lesions in T2 detected with the MRI."@en ;
                      rdfs:label "totalLesionsT2MRI"@en .


###  https://w3id.org/brainteaser/ontology/schema/totalSleepDuration
bto:totalSleepDuration rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:SleepData ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Total sleep duration registered by the wearable device. [uom: seconds]"@en ;
                       rdfs:label "totalSleepDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/traumaDate
bto:traumaDate rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:Trauma ;
               rdfs:range xsd:date ;
               rdfs:comment "The calendar date in which the trauma occurred."@en ;
               rdfs:label "traumaDate"@en .


###  https://w3id.org/brainteaser/ontology/schema/traumaDescription
bto:traumaDescription rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:Trauma ;
                      rdfs:range rdf:PlainLiteral ;
                      rdfs:comment "A description of the trauma"@en ;
                      rdfs:label "traumaDescription"@en .


###  https://w3id.org/brainteaser/ontology/schema/unitOfMeasure
bto:unitOfMeasure rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:LaboratoryTestResult ;
                  rdfs:range rdf:PlainLiteral ;
                  rdfs:comment "The unit of measure of reference of the laboratory test result."@en ;
                  rdfs:label "unitOfMeasure"@en .


###  https://w3id.org/brainteaser/ontology/schema/unmeasurableSleepDuration
bto:unmeasurableSleepDuration rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:SleepData ;
                              rdfs:range xsd:float ;
                              rdfs:comment "Unmeasurable sleep duration registered by the wearable device. [uom: seconds]"@en ;
                              rdfs:label "unmeasurableSleepDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/upperLimbSurgery
bto:upperLimbSurgery rdf:type owl:DatatypeProperty ;
                     rdfs:domain [ rdf:type owl:Class ;
                                   owl:unionOf ( bto:Last5YearsEvent
                                                 bto:MoreThan5YearsEvent
                                               )
                                 ] ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether a patient had an upper limb surgery."@en ;
                     rdfs:label "upperLimbSurgery"@en .


###  https://w3id.org/brainteaser/ontology/schema/validMeasurements
bto:validMeasurements rdf:type owl:DatatypeProperty ;
                      rdfs:domain [ rdf:type owl:Class ;
                                    owl:unionOf ( <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration>
                                                  bto:WeatherData
                                                )
                                  ] ;
                      rdfs:range xsd:integer ;
                      rdfs:comment "For each recorded variable, number of valid measurements in that week, ranging from 0 to 7."@en ;
                      rdfs:label "validMeasurements"@en .


###  https://w3id.org/brainteaser/ontology/schema/vigorousIntensityDuration
bto:vigorousIntensityDuration rdf:type owl:DatatypeProperty ;
                              rdfs:domain bto:PhysicalActivityData ;
                              rdfs:range xsd:float ;
                              rdfs:comment "Vigorous intensity duration registered by the wearable device. [uom: seconds]"@en ;
                              rdfs:label "vigorousIntensityDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/virusJCTestedCSF
bto:virusJCTestedCSF rdf:type owl:DatatypeProperty ,
                              owl:FunctionalProperty ;
                     rdfs:domain bto:CSFAnalysis ;
                     rdfs:range xsd:boolean ;
                     rdfs:comment "Whether the presence of JC virus was tested in the CSF specimen."@en ;
                     rdfs:label "virusJCTestedCSF"@en .


###  https://w3id.org/brainteaser/ontology/schema/visualAcuityLeft
bto:visualAcuityLeft rdf:type owl:DatatypeProperty ;
                     rdfs:domain bto:VisualAcuity ;
                     rdfs:range xsd:integer ;
                     rdfs:comment "Visual Acuity Test on the left eye."@en ;
                     rdfs:label "visualAcuityLeft"@en .


###  https://w3id.org/brainteaser/ontology/schema/visualAcuityRight
bto:visualAcuityRight rdf:type owl:DatatypeProperty ;
                      rdfs:domain bto:VisualAcuity ;
                      rdfs:range xsd:integer ;
                      rdfs:comment "Visual Acuity Test on the right eye."@en ;
                      rdfs:label "visualAcuityRight"@en .


###  https://w3id.org/brainteaser/ontology/schema/visualEDSS
bto:visualEDSS rdf:type owl:DatatypeProperty ,
                        owl:FunctionalProperty ;
               rdfs:domain bto:EDSS ;
               rdfs:range xsd:integer ;
               rdfs:comment "Expanded Disability Status Score (EDSS) score for visual (optic) functions."@en ;
               rdfs:label "visualEDSS"@en .


###  https://w3id.org/brainteaser/ontology/schema/visualEvokedPotentialAmplitude
bto:visualEvokedPotentialAmplitude rdf:type owl:DatatypeProperty ,
                                            owl:FunctionalProperty ;
                                   rdfs:domain bto:EvokedPotentials ;
                                   rdfs:range xsd:float ;
                                   rdfs:comment "The amplitude for the Visual Evoked Potential (VEP) wave. [Source: Wikipedia - consulted on November 25th, 2022] Unit of Measure: [uV]."@en ;
                                   rdfs:label "visualEvokedPotentialAmplitude"@en ;
                                   skos:note "This data property can only be used for Evoked Potential of type 'visual'."@en .


###  https://w3id.org/brainteaser/ontology/schema/visualEvokedPotentialLatency
bto:visualEvokedPotentialLatency rdf:type owl:DatatypeProperty ,
                                          owl:FunctionalProperty ;
                                 rdfs:domain bto:EvokedPotentials ;
                                 rdfs:range xsd:integer ;
                                 rdfs:comment "The average peak latency for the Visual Evoked Potential (VEP) wave at approximately 100 ms following stimulus onset. [Source: Wikipedia - consulted on November 25th, 2022] Unit of Measure: [microsec]."@en ;
                                 rdfs:label "visualEvokedPotentialLatency"@en ;
                                 skos:note "This data property can only be used for Evoked Potential of type 'visual'."@en .


###  https://w3id.org/brainteaser/ontology/schema/visualRelapse
bto:visualRelapse rdf:type owl:DatatypeProperty ,
                           owl:FunctionalProperty ;
                  rdfs:domain bto:Relapse ;
                  rdfs:range xsd:boolean ;
                  rdfs:comment "Whether the relapse involved visual functions."@en ;
                  rdfs:label "visualRelapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/walkAssistiveDevice
bto:walkAssistiveDevice rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:WalkTest ;
                        rdfs:range xsd:boolean ;
                        rdfs:comment "Whether the patient uses an assistive device for walking."@en ;
                        rdfs:label "walkAssistiveDevice"@en .


###  https://w3id.org/brainteaser/ontology/schema/walkAssistiveDeviceUsed
bto:walkAssistiveDeviceUsed rdf:type owl:DatatypeProperty ;
                            rdfs:domain bto:WalkTest ;
                            rdfs:range rdf:PlainLiteral ;
                            rdfs:comment "The type of assistive device used for walking."@en ;
                            rdfs:label "walkAssistiveDeviceUsed"@en .


###  https://w3id.org/brainteaser/ontology/schema/walkTestNotCompleted
bto:walkTestNotCompleted rdf:type owl:DatatypeProperty ;
                         rdfs:domain bto:WalkTest ;
                         rdfs:range xsd:boolean ;
                         rdfs:comment "Whether the walk test was completed."@en ;
                         rdfs:label "walkTestNotCompleted"@en .


###  https://w3id.org/brainteaser/ontology/schema/walkingTime10Meters
bto:walkingTime10Meters rdf:type owl:DatatypeProperty ;
                        rdfs:domain bto:WalkTestALS ;
                        rdfs:range xsd:float ;
                        rdfs:comment "Time to walk 10 meters."@en ;
                        rdfs:label "walkingTime10Meters"@en .


###  https://w3id.org/brainteaser/ontology/schema/walkingTime25Steps
bto:walkingTime25Steps rdf:type owl:DatatypeProperty ;
                       rdfs:domain bto:WalkTestMS ;
                       rdfs:range xsd:float ;
                       rdfs:comment "Time to take 25 steps."@en ;
                       rdfs:label "walkingTime25Steps"@en .


###  https://w3id.org/brainteaser/ontology/schema/wdmDuration
bto:wdmDuration rdf:type owl:DatatypeProperty ;
                rdfs:domain bto:WearableDataMeasurement ;
                rdfs:range xsd:integer ;
                rdfs:comment "The duration of the measurement."@en ;
                rdfs:label "wearableDataMeasurementDuration"@en .


###  https://w3id.org/brainteaser/ontology/schema/wdmStartTime
bto:wdmStartTime rdf:type owl:DatatypeProperty ;
                 rdfs:domain bto:WearableDataMeasurement ;
                 rdfs:range xsd:dateTime ;
                 rdfs:comment "The timestamp in which the measurement started."@en ;
                 rdfs:label "wearableDataMeasurementStartTime"@en .


###  https://w3id.org/brainteaser/ontology/schema/weeklyFrequency
bto:weeklyFrequency rdf:type owl:DatatypeProperty ;
                    rdfs:domain bto:PhysicalActivity ;
                    rdfs:range xsd:float ;
                    rdfs:comment "The number of hours per week physical activity takes place."@en ;
                    rdfs:label "weeklyFrequency"@en .


###  https://w3id.org/brainteaser/ontology/schema/weight
bto:weight rdf:type owl:DatatypeProperty ,
                    owl:FunctionalProperty ;
           rdfs:domain bto:ClinicalEvaluation ;
           rdfs:range xsd:float ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005910" ;
           rdfs:comment "Measurement of quantity by means of weighing; quantity (in the abstract) as determined in this way. [Definition Source: Oxford English Dictionary]"@en ;
           rdfs:label "weight"@en .


###  https://w3id.org/brainteaser/ontology/schema/whoThresholdExceeded
bto:whoThresholdExceeded rdf:type owl:DatatypeProperty ;
                         rdfs:domain <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration> ;
                         rdfs:range xsd:integer ;
                         rdfs:comment """Number of days spent over the respective World Health Organization (WHO) threshold in that week (computed as following); if there are no valid measurements in that week, it is denoted as NA. 

* For Carbon Monoxide (CO): if CO ≤ 4 mg/m3 then the value is 0; otherwise, it is 1
* For Nitrogen Dioxide (NO 2 ): if NO 2 ≤ 25 µg/m3 then the value is 0; otherwise, it is 1
* For Ozone (O3): if O 3 ≤ 100 µg/m3 then the value is 0; otherwise, it is 1
* For Particulate Matter with a diameter of 2.5 micrometers or smaller (PM 2.5): if PM 2.5 ≤ 15
µg/m 3 then the value is 0; otherwise, it is 1
* For Particulate Matter with a diameter of 10 micrometers or smaller (PM 10 ): if PM 10 ≤ 45 µg/m3 , then the value is 0; otherwise, it is 1
* For Sulfur Dioxide (SO 2 ); if SO 2 ≤ 40 µg/m3 , then the value is 0; otherwise, it is 1"""@en ;
                         rdfs:label "whoThresholdExceeded"@en .


###  https://w3id.org/brainteaser/ontology/schema/zipCode
bto:zipCode rdf:type owl:DatatypeProperty ,
                     owl:FunctionalProperty ;
            rdfs:domain bto:Place ;
            rdfs:range rdf:PlainLiteral ;
            rdfs:comment "A group of letters or numbers, or both, added to a postal address to facilitate the sorting and delivery of mail. Later also: the area designated by such a code. [Definition Source: Oxford English Dictionary]"@en ;
            rdfs:label "zipCode"@en .


###  https://w3id.org/brainteaser/ontology/schema/zipHashed
bto:zipHashed rdf:type owl:DatatypeProperty ,
                       owl:FunctionalProperty ;
              rdfs:domain bto:Place ;
              rdfs:range rdf:PlainLiteral ;
              rdfs:comment "The zip code hashed for privacy reasons."@en ;
              rdfs:label "zipHashed"@en .


#################################################################
#    Classes
#################################################################

###  http://www.w3.org/2000/10/swap/pim/contact#Person
<http://www.w3.org/2000/10/swap/pim/contact#Person> rdf:type owl:Class ;
                                                    rdfs:comment "A human being. [Definition Source: NCI]"@en ;
                                                    rdfs:label "Person"@en .


###  http://www.w3.org/2004/02/skos/core#Concept
skos:Concept rdf:type owl:Class .


###  https://w3id.org/brainteaser/ontology/schema/ALSBrainteaserComorbidities
bto:ALSBrainteaserComorbidities rdf:type owl:Class ;
                                rdfs:subClassOf bto:UseCaseComorbidities ;
                                rdfs:comment "Comorbidities checked for ALS patient in the BRAINTEASER study."@en ;
                                rdfs:label "ALS Brainteaser Comorbidities"@en .


###  https://w3id.org/brainteaser/ontology/schema/ALSFRS
bto:ALSFRS rdf:type owl:Class ;
           rdfs:subClassOf bto:Questionnaire ;
           rdfs:comment "The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) is an instrument for evaluating the functional status of patients with Amyotrophic Lateral Sclerosis. It can be used to monitor functional change in a patient over time.  [Definition Source: Georgetown University Hospital - Medstar Health]"@en ;
           rdfs:label "Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)"@en .


###  https://w3id.org/brainteaser/ontology/schema/Activity
bto:Activity rdf:type owl:Class ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0441655" ;
             rdfs:comment "An active process; excludes processes and mechanisms which fulfill biological functions. [Definition Source: NCI]"@en ;
             rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C43431" ;
             rdfs:label "Activity"@en ;
             skos:note "In our data we refer to it as \"Behaviour\"."@en .


###  https://w3id.org/brainteaser/ontology/schema/Administration
bto:Administration rdf:type owl:Class ;
                   dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1533734" ;
                   rdfs:comment "The act of the dispensing, applying, or tendering of something to another, such as administration of a medicine. [Definition Source: NCI]"@en ;
                   rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C25409" ;
                   rdfs:label "Administration"@en .


###  https://w3id.org/brainteaser/ontology/schema/AdverseDrugReaction
bto:AdverseDrugReaction rdf:type owl:Class ;
                        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0041755" ;
                        rdfs:comment "Any detrimental or unintended response associated with the use of a medication in humans. [Definition Source: NCI]"@en ;
                        rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C142385" ;
                        rdfs:label "Adverse Drug Reaction"@en .


###  https://w3id.org/brainteaser/ontology/schema/AnatomicalSite
bto:AnatomicalSite rdf:type owl:Class ;
                   dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1515974" ;
                   rdfs:comment "Named locations of or within the body. [Definition Source: NCI]"@en ;
                   rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C13717" ;
                   rdfs:label "Anatomic Site"@en .


###  https://w3id.org/brainteaser/ontology/schema/AppQuestionnaire
bto:AppQuestionnaire rdf:type owl:Class ;
                     dcterms:conformsTo UMLS:C0034394 ;
                     rdfs:comment "A predetermined set of questions. [Definition Source: NCI]"@en ;
                     rdfs:isDefinedBy NCIT:C17048 ;
                     rdfs:label "Questionnaire filled using a mobile application"@en .


###  https://w3id.org/brainteaser/ontology/schema/AtmosphericPressure
bto:AtmosphericPressure rdf:type owl:Class ;
                        rdfs:subClassOf bto:WeatherData ;
                        dcterms:conformsTo UMLS:C0004180 ;
                        rdfs:comment "The pressure at any point in an atmosphere due solely to the weight of the atmospheric gases bove the point concerned. [Definition Source: MSH]"@en ;
                        rdfs:label "Atmospheric Pressure"@en .


###  https://w3id.org/brainteaser/ontology/schema/AvgRelHumidity
bto:AvgRelHumidity rdf:type owl:Class ;
                   rdfs:subClassOf bto:Humidity ;
                   rdfs:label "Daily Average Relative Humidity"@en .


###  https://w3id.org/brainteaser/ontology/schema/AvgSeaLvlPressure
bto:AvgSeaLvlPressure rdf:type owl:Class ;
                      rdfs:subClassOf bto:AtmosphericPressure ;
                      rdfs:label "Daily Average Sea Level Pressure"@en .


###  https://w3id.org/brainteaser/ontology/schema/AwajiClinicalEvaluation
bto:AwajiClinicalEvaluation rdf:type owl:Class ;
                            rdfs:subClassOf bto:DiagnosticProcedure ;
                            rdfs:comment "Diagnostic assessment of ALS following the Awaji reccomendations (doi.org/10.1016/j.clinph.2007.09.143)."@en ;
                            rdfs:label "Awaji Clinical Evaluation"@en .


###  https://w3id.org/brainteaser/ontology/schema/BVMTR
bto:BVMTR rdf:type owl:Class ;
          rdfs:subClassOf bto:CognitiveAssessment ;
          rdfs:comment "The BVMT-R measures Visuospatial Memory for Patients with Head Trauma, LD, Psychiatric Disorder, and Mixed Diagnoses. [Source: https://www.parinc.com/Products/Pkey/30#:~:text=A%20Measure%20of%20Visuospatial%20Memory,to%20document%20changes%20over%20time.]"@en ;
          rdfs:label "Brief Visuospatial Memory Test-Revised "@en .


###  https://w3id.org/brainteaser/ontology/schema/BeatToBeatData
bto:BeatToBeatData rdf:type owl:Class ;
                   rdfs:subClassOf bto:WearableDataMeasurement ;
                   rdfs:comment "Beat-To-Beat Data registered by a wearable device."@en ;
                   rdfs:label "Beat-To-Beat Data"@en .


###  https://w3id.org/brainteaser/ontology/schema/BeforeOnset
bto:BeforeOnset rdf:type owl:Class ;
                rdfs:subClassOf bto:Event ;
                rdfs:comment "Any event that happened to a patient before the onset."@en ;
                rdfs:label "Before Onset"@en .


###  https://w3id.org/brainteaser/ontology/schema/C6H6_concentration
bto:C6H6_concentration rdf:type owl:Class ;
                       rdfs:subClassOf <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration> ;
                       rdfs:label "Benzene concentration"@en .


###  https://w3id.org/brainteaser/ontology/schema/CO_concentration
bto:CO_concentration rdf:type owl:Class ;
                     rdfs:subClassOf <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration> ;
                     rdfs:comment "The determination of the amount of carbon monoxide present in a sample. [Definition Source: NCI]"@en ;
                     rdfs:label "Carbon Monoxide concentration"@en .


###  https://w3id.org/brainteaser/ontology/schema/CSFAnalysis
bto:CSFAnalysis rdf:type owl:Class ;
                rdfs:subClassOf bto:DiagnosticProcedure ;
                dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2026522" ;
                rdfs:comment "A laboratory analysis of a sample of cerebrospinal fluid. [Definition Source: NCI]"@en ;
                rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C173272" ;
                rdfs:label "CSF Analysis"@en .


###  https://w3id.org/brainteaser/ontology/schema/CVLTII
bto:CVLTII rdf:type owl:Class ;
           rdfs:subClassOf bto:CognitiveAssessment ;
           dcterms:conformsTo UMLS:C3899729 ;
           rdfs:comment "The second version of California Verbal Learning Test, a neuropsychological test developed to make a comprehensive and detailed assessment of verbal learning and memory in individuals ranging in age from 16 to 89 years. [Definition Source: NCI]"@en ;
           rdfs:isDefinedBy NCIT:C120257 ;
           rdfs:label "California Verbal Learning Test - Second Edition"@en .


###  https://w3id.org/brainteaser/ontology/schema/ClinicalEvaluation
bto:ClinicalEvaluation rdf:type owl:Class ;
                       rdfs:subClassOf bto:DiagnosticProcedure ;
                       dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1261322" ;
                       rdfs:comment "An assessment of an individual's physical, mental, or emotional condition; information can be gathered from multiple sources, including physical exam, personal interview and observation, medical history, laboratory and imaging tests. [Definition Source: NCI]"@en ;
                       rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C124351" ;
                       rdfs:label "Clinical Evaluation"@en .


###  https://w3id.org/brainteaser/ontology/schema/ClinicalTrial
bto:ClinicalTrial rdf:type owl:Class ;
                  dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0008976" ;
                  rdfs:comment "A research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. [Definition Source: NCI]"@en ;
                  rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C71104" ;
                  rdfs:label "Clinical Trial"@en .


###  https://w3id.org/brainteaser/ontology/schema/ClinicalTrialParticipation
bto:ClinicalTrialParticipation rdf:type owl:Class ;
                               dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C4041024" ;
                               rdfs:comment "The participation in a clinical trial"@en ;
                               rdfs:isDefinedBy "http://purl.bioontology.org/ontology/SNOMEDCT/709491003" ;
                               rdfs:label "Clinical Trial Participation"@en .


###  https://w3id.org/brainteaser/ontology/schema/ClinicsAndHospitals
bto:ClinicsAndHospitals rdf:type owl:Class ;
                        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0587906" ;
                        rdfs:comment "Institutions with an organized medical staff for the medical care, treatment, and cure of the sick and wounded, for the study of disease, and for the training of physicians, nurses, and allied health personnel. [Definition Source: NCI]"@en ;
                        rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C19326" ;
                        rdfs:label "Clinics and Hospitals"@en .


###  https://w3id.org/brainteaser/ontology/schema/CognitiveAssessment
bto:CognitiveAssessment rdf:type owl:Class ;
                        rdfs:subClassOf bto:DiagnosticProcedure ;
                        dcterms:conformsTo UMLS:C0870300 ;
                        rdfs:comment "The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. [Definition Source: NCI]"@en ;
                        rdfs:isDefinedBy NCIT:C62736 ;
                        rdfs:label "Cognitive Assessment"@en .


###  https://w3id.org/brainteaser/ontology/schema/Comorbidity
bto:Comorbidity rdf:type owl:Class ;
                rdfs:subClassOf bto:Condition ;
                dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0009488" ;
                rdfs:comment "The coexistence of two or more disease processes. [Definition Source: NCI]"@en ;
                rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C16457" ;
                rdfs:label "Comorbidity"@en .


###  https://w3id.org/brainteaser/ontology/schema/Condition
bto:Condition rdf:type owl:Class ;
              dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0348080" ;
              rdfs:comment "A state of being, such as a state of health. [Definition Source: NCI]"@en ;
              rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C25457" ;
              rdfs:label "Condition"@en .


###  https://w3id.org/brainteaser/ontology/schema/DYMUS
bto:DYMUS rdf:type owl:Class ;
          rdfs:subClassOf bto:AppQuestionnaire ;
          rdfs:comment "A questionnaire to assess dysphagia in MS patients [DOI: 10.1016/j.jns.2007.12.021]"@en ;
          rdfs:label "Dysphagia In Multiple Sclerosis"@en .


###  https://w3id.org/brainteaser/ontology/schema/Diagnosis
bto:Diagnosis rdf:type owl:Class ;
              rdfs:subClassOf bto:Event ;
              dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011900" ;
              rdfs:comment "The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. [Definition Source: NCI]"@en ;
              rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C15220" ;
              rdfs:label "Diagnosis"@en .


###  https://w3id.org/brainteaser/ontology/schema/DiagnosticImaging
bto:DiagnosticImaging rdf:type owl:Class ;
                      rdfs:subClassOf bto:DiagnosticProcedure ;
                      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011923" ;
                      rdfs:comment "Any method that uses a visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. [Definition Source: NCI]"@en ;
                      rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C16502" ;
                      rdfs:label "Diagnostic Imaging"@en .


###  https://w3id.org/brainteaser/ontology/schema/DiagnosticProcedure
bto:DiagnosticProcedure rdf:type owl:Class ;
                        rdfs:subClassOf bto:InterventionOrProcedure ;
                        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0430022" ;
                        rdfs:comment "Any procedure or test to diagnose a disease or disorder. [Definition Source: NCI]"@en ;
                        rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C18020" ;
                        rdfs:label "Diagnostic Procedure"@en .


###  https://w3id.org/brainteaser/ontology/schema/DiseaseDisorderOrFinding
bto:DiseaseDisorderOrFinding rdf:type owl:Class ;
                             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1511989" ;
                             rdfs:comment "A condition that is relevant to human neoplasms and non-neoplastic disorders. This includes observations, test results, history and other concepts relevant to the characterization of human pathologic conditions. [Definition Source: NCI]"@en ;
                             rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C7057" ;
                             rdfs:label "Disease, Disorder or Finding"@en .


###  https://w3id.org/brainteaser/ontology/schema/ECAS
bto:ECAS rdf:type owl:Class ;
         rdfs:subClassOf bto:CognitiveAssessment ;
         rdfs:comment "The ECAS is a brief multidomain assessment originally designed for people with Amyotrophic Lateral Sclerosis (ALS/Motor Neurone Disease) but is also useful in other neurodegenerative disorders. [Source: https://ecas.psy.ed.ac.uk/]"@en ;
         rdfs:label "Edinburgh Cognitive and Behavioural ALS Screen"@en .


###  https://w3id.org/brainteaser/ontology/schema/EDSS
bto:EDSS rdf:type owl:Class ;
         rdfs:subClassOf bto:DiagnosticProcedure ;
         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0451246" ;
         rdfs:comment "A system for quantifying disability in multiple sclerosis (MS). Based on a standard neurological examination, the Expanded Disability Status Scale quantifies disability in seven Functional Systems (plus \"Other\") and assigns a Functional System Score in each. Results are ranked as steps from 0 to 10, with steps 1 through 4.5 describing MS patients who are fully ambulatory and steps 5 through 9.5 describing increasing impairment to ambulation. Step 10 refers to death due to MS. [Definition Source: NCI]"@en ;
         rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C98302" ;
         rdfs:label "Expanded Disability Status Scale (EDSS)"@en .


###  https://w3id.org/brainteaser/ontology/schema/EQ5D5L
bto:EQ5D5L rdf:type owl:Class ;
           rdfs:subClassOf bto:AppQuestionnaire ;
           dcterms:conformsTo UMLS:C3640517 ;
           rdfs:comment "A standardized rating scale which is used as a measure of health outcome. This instrument is a descriptive system consisting of 5 dimensions: mobility, self-care, usual activity, pain/discomfort, and anxiety/depression. Each dimension has 5 levels ranging from no problem to extreme problem or incapable, which are assessed by the patient. [Definition Source: NCI]"@en ;
           rdfs:isDefinedBy NCIT:C102117 ;
           rdfs:label "European Quality of Life Five Dimension Five Level Scale Questionnaire"@en .


###  https://w3id.org/brainteaser/ontology/schema/EndTherapyReason
bto:EndTherapyReason rdf:type owl:Class ;
                     rdfs:comment "The motivation for the interruption of the therapeutic treatment."@en ;
                     rdfs:label "End Therapy Reason"@en .


###  https://w3id.org/brainteaser/ontology/schema/Event
bto:Event rdf:type owl:Class ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0441471" ;
          rdfs:comment "Something that happens at a given place and time. [Definition Source: NCI]"@en ;
          rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C25499" ;
          rdfs:label "Event"@en .


###  https://w3id.org/brainteaser/ontology/schema/EvokedPotentials
bto:EvokedPotentials rdf:type owl:Class ;
                     rdfs:subClassOf bto:DiagnosticProcedure ;
                     dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015214" ;
                     rdfs:comment "Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported. [Definition Source: MSH]"@en ;
                     rdfs:isDefinedBy "http://purl.bioontology.org/ontology/SNOMEDCT/386205007" ;
                     rdfs:label "Evoked Potentials"@en .


###  https://w3id.org/brainteaser/ontology/schema/Gene
bto:Gene rdf:type owl:Class ;
         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0017337" ;
         rdfs:comment "A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function. [Definition Source: NCI]"@en ;
         rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C16612" ;
         rdfs:label "Gene"@en .


###  https://w3id.org/brainteaser/ontology/schema/GeneticTesting
bto:GeneticTesting rdf:type owl:Class ;
                   dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0679560" ;
                   rdfs:comment "The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. [Definition Source: NCI]"@en ;
                   rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C15709" ;
                   rdfs:label "Genetic Testing"@en .


###  https://w3id.org/brainteaser/ontology/schema/GlobalRadiation
bto:GlobalRadiation rdf:type owl:Class ;
                    rdfs:subClassOf bto:WeatherData ;
                    rdfs:label "Global Radiation"@en .


###  https://w3id.org/brainteaser/ontology/schema/GoldCoastCriteria
bto:GoldCoastCriteria rdf:type owl:Class ;
                      rdfs:subClassOf bto:DiagnosticProcedure ;
                      rdfs:comment "Diagnostic assessment of ALS following the Gold Coast criteria (doi.org/10.1136/practneurol-2021-003256 )."@en ;
                      rdfs:label "Gold Coast Diagnosis Criteria"@en .


###  https://w3id.org/brainteaser/ontology/schema/Group
bto:Group rdf:type owl:Class ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1257890" ;
          rdfs:comment "A group of individuals united by a common factor (e.g., geographic location, ethnicity, disease, age, gender) [Definition Source: NCI]"@en ;
          rdfs:isDefinedBy "http://purl.bioontology.org/ontology/SNOMEDCT/389109008" ;
          rdfs:label "Group (social concept)"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS
bto:HADS rdf:type owl:Class ;
         rdfs:subClassOf bto:AppQuestionnaire ;
         dcterms:conformsTo UMLS:C3539657 ;
         rdfs:comment "A standardized survey developed and copyrighted by A. S. Zigmond and R. P. Snaith in 1983, 1992, 1994 and published in the Acta Psychiatrica Scandinavica journal (A.S. Zigmond and R.P. Snaith. The Hospital Anxiety and Depression Scale. Acta psychiart. scand. 1983, 67:361-370) which is used to detect depression and anxiety in individuals in a hospital or medical outpatient clinic. This instrument is a self-administered questionnaire consisting of 14 items that assess how the individual has felt over the past week. Each item as 4 response options that are associated with a score of 0 to 3. [Definition Source: NCI]"@en ;
         rdfs:isDefinedBy NCIT:C103520 ;
         rdfs:label "Hospital Anxiety and Depression Scale"@en .


###  https://w3id.org/brainteaser/ontology/schema/HADS_ALS
bto:HADS_ALS rdf:type owl:Class ;
             rdfs:subClassOf bto:HADS ;
             rdfs:comment "Hospital Anxiety and Depression Scale questionnaire administered to ALS patients."@en ;
             rdfs:label "Hospital Anxiety and Depression Scale for ALS patients"@en .


###  https://w3id.org/brainteaser/ontology/schema/HandDexterity
bto:HandDexterity rdf:type owl:Class ;
                  rdfs:subClassOf bto:DiagnosticProcedure ;
                  rdfs:comment "Test performed to assess the ability of a person to use the fingers, hands and arms to perform a task. [Definition Source: physio-pedia.com]"@en ;
                  rdfs:label "Hand Dexterity"@en .


###  https://w3id.org/brainteaser/ontology/schema/HeartRateMeasurement
bto:HeartRateMeasurement rdf:type owl:Class ;
                         rdfs:subClassOf bto:WearableDataMeasurement ;
                         dcterms:conformsTo UMLS:C0018810 ;
                         rdfs:comment "The number of heartbeats per unit of time, usually expressed as beats per minute. [Definition Source: NCI]"@en ;
                         rdfs:isDefinedBy NCIT:C49677 ;
                         rdfs:label "Heart Rate Measurement"@en .


###  https://w3id.org/brainteaser/ontology/schema/HematologyTest
bto:HematologyTest rdf:type owl:Class ;
                   rdfs:subClassOf bto:DiagnosticProcedure ;
                   dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0200627" ;
                   rdfs:comment "A laboratory test to measure hematopoietic components and investigate hematologic disorders in a blood sample. [Definition Source: NCI]"@en ;
                   rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C49286" ;
                   rdfs:label "Hematology Test"@en .


###  https://w3id.org/brainteaser/ontology/schema/Humidity
bto:Humidity rdf:type owl:Class ;
             rdfs:subClassOf bto:WeatherData ;
             dcterms:conformsTo UMLS:C0020167 ;
             rdfs:comment "A measure of the water vapor content of air. [Definition Source: NCI]"@en ;
             rdfs:isDefinedBy NCIT:C88206 ;
             rdfs:label "Humidity"@en .


###  https://w3id.org/brainteaser/ontology/schema/Impairment
bto:Impairment rdf:type owl:Class ;
               rdfs:subClassOf bto:Condition ;
               dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0221099" ;
               rdfs:comment "Loss or abnormality of psychological, physiological, or anatomic structure or function. [Definition Source: NCI]"@en ;
               rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C21055" ;
               rdfs:label "Impairment"@en .


###  https://w3id.org/brainteaser/ontology/schema/InterventionOrProcedure
bto:InterventionOrProcedure rdf:type owl:Class ;
                            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0184661" ;
                            rdfs:comment "An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects. [Definition Source: NCI]"@en ;
                            rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C25218" ;
                            rdfs:label "Intervention or Procedure"@en .


###  https://w3id.org/brainteaser/ontology/schema/KingsClinicalStaging
bto:KingsClinicalStaging rdf:type owl:Class ;
                         rdfs:subClassOf bto:Questionnaire ;
                         rdfs:comment "The King’s staging system consists of five disease stages, with Stage 5 being death. Stages 1–3 are based upon the number of El Escorial central nervous system (CNS) regions involved in the disease, measured by weakness, wasting, spasticity, dysphagia, or dysarthria. Stage 4 is nutritional failure, defined by the requirement for gastrostomy, or respiratory failure, defined by the requirement for noninvasive ventilation (NIV), and based upon the National Institute for Clinical Excellence MND Guidelines (Supplemental Material). [Definition Source: Balendra, Rubika et al. “A standard operating procedure for King's ALS clinical staging.” Amyotrophic lateral sclerosis & frontotemporal degeneration vol. 20,3-4 (2019): 159-164.]"@en ;
                         rdfs:label "King's Clinical Staging Method"@en .


###  https://w3id.org/brainteaser/ontology/schema/Kinship
bto:Kinship rdf:type owl:Class ;
            rdfs:comment "The relationship between members of the same family. [Cambridge Dictionary]"@en ;
            rdfs:isDefinedBy "https://dictionary.cambridge.org/dictionary/english/kinship" ;
            rdfs:label "Kinship"@en ;
            skos:note "This class is always instantiated as a blank node"@en .


###  https://w3id.org/brainteaser/ontology/schema/KinshipType
bto:KinshipType rdf:type owl:Class ;
                rdfs:comment "The type of the relationship between members of the same family."@en ;
                rdfs:label "KinshipType"@en ;
                skos:note "For the purpose of our ontology, we only consider biological kinship. We omit the word \"biological\" from the invidual's labels, for example \"father\" refers to \"biological father\"."@en .


###  https://w3id.org/brainteaser/ontology/schema/LaboratoryTestResult
bto:LaboratoryTestResult rdf:type owl:Class ;
                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0587081" ;
                         rdfs:comment "The outcome of a laboratory test. [Definition Source: NCI]"@en ;
                         rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C36292" ;
                         rdfs:label "Laboratory Test Result"@en .


###  https://w3id.org/brainteaser/ontology/schema/Last5YearsEvent
bto:Last5YearsEvent rdf:type owl:Class ;
                    rdfs:subClassOf bto:BeforeOnset ;
                    rdfs:comment "Events occurred in the last 5 years (from the first visit)."@en ;
                    rdfs:label "Last 5 Years Event"@en .


###  https://w3id.org/brainteaser/ontology/schema/Lifestyle
bto:Lifestyle rdf:type owl:Class ;
              rdfs:subClassOf bto:Activity ;
              dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0023676" ;
              rdfs:comment "A manner of living that reflects the person's values and attitudes. [Definition Source: NCI]"@en ;
              rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C16795" ;
              rdfs:label "Lifestyle"@en .


###  https://w3id.org/brainteaser/ontology/schema/MFIS
bto:MFIS rdf:type owl:Class ;
         rdfs:subClassOf bto:AppQuestionnaire ;
         dcterms:conformsTo UMLS:C3810705 ;
         rdfs:comment "A standardized rating scale developed by Fisk et al in 1994, which assesses how fatigue may affect a person and the impact of fatigue on quality of life. The questionnaire contains 21 questions which are scored ranging from 0 (never) to 4 (almost always). [Definition Source: NCI]"@en ;
         rdfs:isDefinedBy NCIT:C113877 ;
         rdfs:label "Modified Fatigue Impact Scale"@en .


###  https://w3id.org/brainteaser/ontology/schema/MRI
bto:MRI rdf:type owl:Class ;
        rdfs:subClassOf bto:DiagnosticImaging ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0024485" ;
        rdfs:comment "Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders. [Definition Source: NCI]"@en ;
        rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C16809" ;
        rdfs:label "Magnetic Resonance Imaging (MRI)"@en .


###  https://w3id.org/brainteaser/ontology/schema/MSQOL54
bto:MSQOL54 rdf:type owl:Class ;
            rdfs:subClassOf bto:AppQuestionnaire ;
            dcterms:conformsTo UMLS:C3826975 ;
            rdfs:comment "A standardized rating scale developed by Vickrey et al in 1995 and 1997, which combines items that are generic and disease-specific to assess quality of life and the level of physical, emotional, and cognitive functions in patients with multiple sclerosis. The questionnaire contains 54 questions and generates 12 subscales: physical function, role limitations due to physical problems, role limitations due to emotional problems, pain, emotional well-being, energy, health perceptions, social function, cognitive function, health distress, sexual function and overall quality of life. [Definition Source: NCI]"@en ;
            rdfs:isDefinedBy NCIT:C113878 ;
            rdfs:label "MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument"@en .


###  https://w3id.org/brainteaser/ontology/schema/MaxTemp
bto:MaxTemp rdf:type owl:Class ;
            rdfs:subClassOf bto:Temperature ;
            rdfs:label "Daily Maximum Temperature"@en .


###  https://w3id.org/brainteaser/ontology/schema/MeanGlobRadiation
bto:MeanGlobRadiation rdf:type owl:Class ;
                      rdfs:subClassOf bto:GlobalRadiation ;
                      rdfs:label "Daily Mean Global Radiation"@en .


###  https://w3id.org/brainteaser/ontology/schema/MeanTemp
bto:MeanTemp rdf:type owl:Class ;
             rdfs:subClassOf bto:Temperature ;
             rdfs:label "Daily Mean Temperature"@en .


###  https://w3id.org/brainteaser/ontology/schema/MeanWindSpeed
bto:MeanWindSpeed rdf:type owl:Class ;
                  rdfs:subClassOf bto:WindSpeed ;
                  rdfs:label "Daily Mean Wind Speed"@en .


###  https://w3id.org/brainteaser/ontology/schema/MenstrualCycle
bto:MenstrualCycle rdf:type owl:Class ;
                   dcterms:conformsTo UMLS:C0025329 ;
                   rdfs:comment "The Menstrual Cycle involves regularly recurring hormonal changes and physiologic endometrial changes during the reproductive period in human females, and some primates, and culminates in partial sloughing of the endometrium (menstruation) in the absence of fertilization. For most women, one cycle takes 28 days. [Definition Source: NCI]"@en ;
                   rdfs:isDefinedBy NCIT:C16838 ;
                   rdfs:label "Menstrual Cycle"@en .


###  https://w3id.org/brainteaser/ontology/schema/MiToSFunctionalStaging
bto:MiToSFunctionalStaging rdf:type owl:Class ;
                           rdfs:subClassOf bto:Questionnaire ;
                           rdfs:comment "The Milano–Torino (MiToS) Staging system comprises six stages, based on functional impairment as assessed by the revised ALS Functional Rating Scale (ALSFRS-R). [Definition Source: Balendra, Rubika et al. “A standard operating procedure for King's ALS clinical staging.” Amyotrophic lateral sclerosis & frontotemporal degeneration vol. 20,3-4 (2019): 159-164.]"@en ;
                           rdfs:label "Milano-Torino Functional Staging System (MiToS)"@en .


###  https://w3id.org/brainteaser/ontology/schema/MinTemp
bto:MinTemp rdf:type owl:Class ;
            rdfs:subClassOf bto:Temperature ;
            rdfs:label "Daily Minimum Temperature"@en .


###  https://w3id.org/brainteaser/ontology/schema/MoreThan5YearsEvent
bto:MoreThan5YearsEvent rdf:type owl:Class ;
                        rdfs:subClassOf bto:BeforeOnset ;
                        rdfs:comment "Events occured more than 5 years ago, counting from the first visit."@en ;
                        rdfs:label "More Than 5 Years Event"@en .


###  https://w3id.org/brainteaser/ontology/schema/MuscleTone
bto:MuscleTone rdf:type owl:Class .


###  https://w3id.org/brainteaser/ontology/schema/MuscleToneALS
bto:MuscleToneALS rdf:type owl:Class ;
                  rdfs:subClassOf bto:MuscleTone ;
                  rdfs:comment "Muscle tone assessment performed to ALS patients."@en ;
                  rdfs:label "Muscle Tone ALS"@en .


###  https://w3id.org/brainteaser/ontology/schema/MuscleToneAssessment
bto:MuscleToneAssessment rdf:type owl:Class ;
                         rdfs:subClassOf bto:DiagnosticProcedure ;
                         dcterms:conformsTo UMLS:C4707572 ;
                         rdfs:comment "Muscle Tone measured by the modified Ashworth scale. The modified Ashworth scale is a muscle tone assessment scale used to assess the resistance experienced during passive range of motion, which does not require any instrumentation and is quick to perform. [Source: ncbi.nlm.nih.gov/books/NBK554572/]"@en ;
                         rdfs:label "Muscle Tone Assessment"@en .


###  https://w3id.org/brainteaser/ontology/schema/MuscleToneMS
bto:MuscleToneMS rdf:type owl:Class ;
                 rdfs:subClassOf bto:MuscleTone ;
                 rdfs:comment "Muscle tone assessment performed to MS patients."@en ;
                 rdfs:label "Muscle Tone MS"@en .


###  https://w3id.org/brainteaser/ontology/schema/Occupation
bto:Occupation rdf:type owl:Class ;
               rdfs:comment "The principal activity that a person does to earn money. [Definition Source: NCI]"@en ;
               rdfs:isDefinedBy "http://data.europa.eu/esco/isco" ;
               rdfs:label "Occupation"@en .


###  https://w3id.org/brainteaser/ontology/schema/OligoclonalBands
bto:OligoclonalBands rdf:type owl:Class ;
                     dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C4048246" ;
                     rdfs:comment "The presence of more than one immunoglobulin band in the serum, urine, or cerebrospinal fluid. It usually results from infectious or immunologic disorders. [Definition Source: NCI]"@en ;
                     rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C113809" ;
                     rdfs:label "Oligoclonal Bands"@en .


###  https://w3id.org/brainteaser/ontology/schema/Onset
bto:Onset rdf:type owl:Class ;
          rdfs:subClassOf bto:Event ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0332162" ;
          rdfs:comment "The start, beginning, or early stages. [Definition Source: NCI]"@en ;
          rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C25279" ;
          rdfs:label "Onset"@en .


###  https://w3id.org/brainteaser/ontology/schema/PET
bto:PET rdf:type owl:Class ;
        rdfs:subClassOf bto:DiagnosticImaging ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032743" ;
        rdfs:comment "A technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered. [Definition Source: NCI]"@en ;
        rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C17007" ;
        rdfs:label "Positron Emission Tomography (PET)"@en .


###  https://w3id.org/brainteaser/ontology/schema/PFTs
bto:PFTs rdf:type owl:Class ;
         rdfs:subClassOf bto:AppQuestionnaire ;
         dcterms:conformsTo UMLS:C0024119 ;
         rdfs:comment "A broad range of tests that are performed to assess how well lungs inhale and exhale air and how efficiently they transfer oxygen into the blood. [Definition Source: NCI]"@en ;
         rdfs:isDefinedBy NCIT:C38081 ;
         rdfs:label "Pulmonary function testing"@en .


###  https://w3id.org/brainteaser/ontology/schema/PM1_concentration
bto:PM1_concentration rdf:type owl:Class ;
                      rdfs:subClassOf <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration> ;
                      rdfs:label "Particulate Matter <1 µm concentration"@en .


###  https://w3id.org/brainteaser/ontology/schema/PSQI
bto:PSQI rdf:type owl:Class ;
         rdfs:subClassOf bto:AppQuestionnaire ;
         dcterms:conformsTo UMLS:C3697468 ;
         rdfs:comment "A self-rated questionnaire which assesses sleep quality and disturbances over a one month time interval. [Definition Source: NCI]"@en ;
         rdfs:isDefinedBy NCIT:C103849 ;
         rdfs:label "Pittsburgh Sleep Quality Index"@en .


###  https://w3id.org/brainteaser/ontology/schema/Patient
bto:Patient rdf:type owl:Class ;
            rdfs:subClassOf <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0030705" ;
            rdfs:comment "A person who receives medical attention, care, or treatment, or who is registered with medical professional or institution with the purpose to receive medical care when necessary. [Definition Source: NCI]"@en ;
            rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C16960" ;
            rdfs:label "Patient"@en .


###  https://w3id.org/brainteaser/ontology/schema/PharmacologicSubstance
bto:PharmacologicSubstance rdf:type owl:Class ;
                           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1254351" ;
                           rdfs:comment "Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances. [Definition Source: NCI]"@en ;
                           rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C1909" ;
                           rdfs:label "Pharmacologic Substance"@en .


###  https://w3id.org/brainteaser/ontology/schema/PhysicalActivity
bto:PhysicalActivity rdf:type owl:Class ;
                     rdfs:subClassOf bto:Activity ;
                     dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0026606" ;
                     rdfs:comment "Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc. [Definition Source: NCI][attribution: from NIDDK Glossary; http://www.niddk.nih.gov/health/nutrit/pubs/glossary/glossaryintro.htm]"@en ;
                     rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C17708" ;
                     rdfs:label "Physical Activity"@en .


###  https://w3id.org/brainteaser/ontology/schema/PhysicalActivityData
bto:PhysicalActivityData rdf:type owl:Class ;
                         rdfs:subClassOf bto:WearableDataMeasurement ;
                         dcterms:conformsTo UMLS:C0026606 ;
                         rdfs:comment "Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc. [Definition Source: NCI]"@en ;
                         rdfs:isDefinedBy NCIT:C17708 ;
                         rdfs:label "Physical Activity Data"@en .


###  https://w3id.org/brainteaser/ontology/schema/Place
bto:Place rdf:type owl:Class ;
          rdfs:comment "A particular part or region of space; a physical locality, a locale; a spot, a location. [Definition Source: Oxford English Dictionary]"@en ;
          rdfs:label "Place"@en .


###  https://w3id.org/brainteaser/ontology/schema/Precipitation
bto:Precipitation rdf:type owl:Class ;
                  rdfs:subClassOf bto:WeatherData ;
                  rdfs:label "Precipitation"@en .


###  https://w3id.org/brainteaser/ontology/schema/PrecipitationSum
bto:PrecipitationSum rdf:type owl:Class ;
                     rdfs:subClassOf bto:Precipitation ;
                     rdfs:label "Daily Precipitation Sum"@en .


###  https://w3id.org/brainteaser/ontology/schema/Pregnancy
bto:Pregnancy rdf:type owl:Class ;
              dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032961" ;
              rdfs:comment "The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. [Definition Source: NCI]"@en ;
              rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C25742" ;
              rdfs:label "Pregnancy"@en .


###  https://w3id.org/brainteaser/ontology/schema/ProtocolEvent
bto:ProtocolEvent rdf:type owl:Class ;
                  rdfs:subClassOf bto:Event ;
                  dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2698908" ;
                  rdfs:comment "Other important events that occur during a trial but are not driven by protocol requirements. [Definition Source: NCI]"@en ;
                  rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C74589" ;
                  rdfs:label "Protocol Event"@en .


###  https://w3id.org/brainteaser/ontology/schema/PulmonaryFunctionTest
bto:PulmonaryFunctionTest rdf:type owl:Class ;
                          rdfs:subClassOf bto:DiagnosticProcedure ;
                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0024119" ;
                          rdfs:comment "A broad range of tests that are performed to assess how well lungs inhale and exhale air and how efficiently they transfer oxygen into the blood. [Definition Source: NCI]"@en ;
                          rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C38081" ;
                          rdfs:label "Pulmonary Function Test"@en .


###  https://w3id.org/brainteaser/ontology/schema/Questionnaire
bto:Questionnaire rdf:type owl:Class ;
                  rdfs:subClassOf bto:DiagnosticProcedure ;
                  dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0034394" ;
                  rdfs:comment "A predetermined set of questions. [Definition Source: NCI]"@en ;
                  rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C17048" ;
                  rdfs:label "Questionnaire"@en .


###  https://w3id.org/brainteaser/ontology/schema/Relapse
bto:Relapse rdf:type owl:Class ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0277556" ;
            rdfs:comment "The return of a disease after a period of remission. [Definition Source: NCI]"@en ;
            rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C38155" ;
            rdfs:label "Relapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/Residence
bto:Residence rdf:type owl:Class ;
              dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0237096" ;
              rdfs:comment "Any address at which a person dwells more than temporarily. [Definition Source: NCI]"@en ;
              rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C25273" ;
              rdfs:label "Residence"@en .


###  https://w3id.org/brainteaser/ontology/schema/RespiratoryData
bto:RespiratoryData rdf:type owl:Class ;
                    rdfs:subClassOf bto:WearableDataMeasurement ;
                    rdfs:comment "Respiratory Data registered by a wearable device."@en ;
                    rdfs:label "Respiratory Data"@en .


###  https://w3id.org/brainteaser/ontology/schema/SDMT
bto:SDMT rdf:type owl:Class ;
         rdfs:subClassOf bto:CognitiveAssessment ;
         dcterms:conformsTo UMLS:C3891405 ;
         rdfs:comment "A standardized rating scale developed by Aaron Smith in 1982, which is used to identify individuals with neurological impairment, as well as to assess divided attention, visual scanning and motor speed. This functional test measures the time to pair abstract symbols with specific numbers with a 90 second time limit. Scoring of this test is based on the total number of correctly coded items from 0-110 in 90 seconds. [Definition Source: NCI]"@en ;
         rdfs:isDefinedBy NCIT:C115793 ;
         rdfs:label "Symbol Digit Modalities Functional Test"@en .


###  https://w3id.org/brainteaser/ontology/schema/SLEEP_ALS
bto:SLEEP_ALS rdf:type owl:Class ;
              rdfs:subClassOf bto:AppQuestionnaire ;
              dcterms:conformsTo UMLS:C5420463 ;
              rdfs:comment "A question about an individual's sleeping. [Definition Source: NCI]"@en ;
              rdfs:isDefinedBy NCIT:C173925 ;
              rdfs:label "Sleep Quality"@en .


###  https://w3id.org/brainteaser/ontology/schema/SPO2Data
bto:SPO2Data rdf:type owl:Class ;
             rdfs:subClassOf bto:WearableDataMeasurement ;
             rdfs:comment "SPO2 Data registered by a wearable device."@en ;
             rdfs:label "SPO2 Data"@en .


###  https://w3id.org/brainteaser/ontology/schema/SelfALSFRSR
bto:SelfALSFRSR rdf:type owl:Class ;
                rdfs:subClassOf bto:AppQuestionnaire ;
                rdfs:comment "ALSFRS-R assessed by the patient using the mobile questionnaires."@en ;
                rdfs:label "Self assessed ALSFRS-R questionnaire"@en .


###  https://w3id.org/brainteaser/ontology/schema/SleepData
bto:SleepData rdf:type owl:Class ;
              rdfs:subClassOf bto:WearableDataMeasurement ;
              dcterms:conformsTo UMLS:C0037313 ;
              rdfs:comment "A natural and periodic state of rest during which consciousness of the world is suspended. [Definition Source: NCI]"@en ;
              rdfs:isDefinedBy NCIT:C73425 ;
              rdfs:label "Sleep Data"@en .


###  https://w3id.org/brainteaser/ontology/schema/Smoking
bto:Smoking rdf:type owl:Class ;
            rdfs:subClassOf bto:Activity ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0037369" ;
            rdfs:comment "The act of puffing and/or inhaling the combustion products of a substance so as to be tasted and absorbed into the bloodstream. [Definition Source: NCI]"@en ;
            rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C154329" ;
            rdfs:label "Smoking"@en .


###  https://w3id.org/brainteaser/ontology/schema/StressLevel
bto:StressLevel rdf:type owl:Class ;
                rdfs:subClassOf bto:WearableDataMeasurement ;
                dcterms:conformsTo UMLS:C0038435 ;
                rdfs:comment "The negative mental, emotional, and physical reactions that occur when environmental stressors are perceived as exceeding the individual's adaptive capacities. [Definition Source: NCI]"@en ;
                rdfs:isDefinedBy NCIT:C35041 ;
                rdfs:label "Stress Level"@en .


###  https://w3id.org/brainteaser/ontology/schema/SurgicalProcedure
bto:SurgicalProcedure rdf:type owl:Class ;
                      rdfs:subClassOf bto:InterventionOrProcedure ;
                      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0543467" ;
                      rdfs:comment "A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery. [Definition Source: NCI]"@en ;
                      rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C15329" ;
                      rdfs:label "Surgical Procedure"@en .


###  https://w3id.org/brainteaser/ontology/schema/SurgicalType
bto:SurgicalType rdf:type owl:Class ;
                 rdfs:comment "It defines some type of surgical procedures a patient could undergo."@en ;
                 rdfs:label "Surgical Procedure Type"@en .


###  https://w3id.org/brainteaser/ontology/schema/Symptom
bto:Symptom rdf:type owl:Class ;
            rdfs:subClassOf bto:Condition ;
            dcterms:conformsTo UMLS:C1457887 ;
            rdfs:comment "Subjective evidence of disease perceived by the patient. [Definition Source: NCI]"@en ;
            rdfs:isDefinedBy NCIT:C4876 ;
            rdfs:label "Symptom"@en .


###  https://w3id.org/brainteaser/ontology/schema/Temperature
bto:Temperature rdf:type owl:Class ;
                rdfs:subClassOf bto:WeatherData ;
                rdfs:comment "The temperature of the surroundings. [Definition Source: NCI]"@en ;
                rdfs:isDefinedBy NCIT:C90380 ;
                rdfs:label "Temperature"@en .


###  https://w3id.org/brainteaser/ontology/schema/TherapeuticProcedure
bto:TherapeuticProcedure rdf:type owl:Class ;
                         rdfs:subClassOf bto:InterventionOrProcedure ;
                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0087111" ;
                         rdfs:comment "An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. [Definition Source: NCI]"@en ;
                         rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C49236" ;
                         rdfs:label "Therapeutic Procedure"@en .


###  https://w3id.org/brainteaser/ontology/schema/TherapeuticProcedureType
bto:TherapeuticProcedureType rdf:type owl:Class ;
                             rdfs:comment "It defines some type of therapeutic procedures that could be administered to a patient."@en ;
                             rdfs:label "Therapeutic Procedure Type"@en .


###  https://w3id.org/brainteaser/ontology/schema/TherapeuticTreatment
bto:TherapeuticTreatment rdf:type owl:Class ;
                         rdfs:comment "The therapeutic treatment that has been administered to a patient."@en ;
                         rdfs:label "Therapeutic Treatment"@en .


###  https://w3id.org/brainteaser/ontology/schema/Trauma
bto:Trauma rdf:type owl:Class ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3263723" ;
           rdfs:comment "Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. [Definition Source: NCI]"@en ;
           rdfs:isDefinedBy "http://purl.obolibrary.org/obo/NCIT_C3671" ;
           rdfs:label "Trauma"@en .


###  https://w3id.org/brainteaser/ontology/schema/UseCaseComorbidities
bto:UseCaseComorbidities rdf:type owl:Class ;
                         rdfs:subClassOf bto:Comorbidity ;
                         rdfs:comment "Comorbidities checked in a specific use-case, e.g. ALS patients in a specific study."@en ;
                         rdfs:label "Use-Case Comorbidities"@en .


###  https://w3id.org/brainteaser/ontology/schema/VAS
bto:VAS rdf:type owl:Class ;
        rdfs:subClassOf bto:AppQuestionnaire ;
        dcterms:conformsTo UMLS:C3536884 ;
        rdfs:comment "A psychometric response scale to assess subjective characteristics or symptoms, which relies upon a continuum of possible result values in between two fixed end-points. [Definition Source: NCI]"@en ;
        rdfs:isDefinedBy NCIT:C121547 ;
        rdfs:label "Visual Analogue Scale"@en .


###  https://w3id.org/brainteaser/ontology/schema/VAS_ALS
bto:VAS_ALS rdf:type owl:Class ;
            rdfs:subClassOf bto:VAS ;
            rdfs:comment "Visual Analogue Scale questionnaire administered to ALS patients."@en ;
            rdfs:label "Visual Analogue Scale for ALS patients"@en .


###  https://w3id.org/brainteaser/ontology/schema/VOC_concentration
bto:VOC_concentration rdf:type owl:Class ;
                      rdfs:subClassOf <http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#Air_pollution_concentration> ;
                      rdfs:label "Volatile Organic Compound concentration"@en .


###  https://w3id.org/brainteaser/ontology/schema/VisualAcuity
bto:VisualAcuity rdf:type owl:Class ;
                 rdfs:subClassOf bto:DiagnosticProcedure ;
                 dcterms:conformsTo UMLS:C0042812 ;
                 rdfs:comment "Sharpness of vision, the ability to discern fine detail. [Definition Source: NCI]"@en ;
                 rdfs:isDefinedBy NCIT:C87149 ;
                 rdfs:label "Visual Acuity"@en .


###  https://w3id.org/brainteaser/ontology/schema/WEIGHT
bto:WEIGHT rdf:type owl:Class ;
           rdfs:subClassOf bto:AppQuestionnaire ;
           dcterms:conformsTo UMLS:C0005910 ;
           rdfs:comment "The weight of a subject. [Definition Source: NCI]"@en ;
           rdfs:isDefinedBy NCIT:C81328 ;
           rdfs:label "Weight"@en .


###  https://w3id.org/brainteaser/ontology/schema/WalkTest
bto:WalkTest rdf:type owl:Class ;
             rdfs:subClassOf bto:DiagnosticProcedure ;
             rdfs:comment "Test performed to assess the walking abilities of patients."@en ;
             rdfs:label "Walk Test"@en .


###  https://w3id.org/brainteaser/ontology/schema/WalkTestALS
bto:WalkTestALS rdf:type owl:Class ;
                rdfs:subClassOf bto:WalkTest ;
                rdfs:comment "Walk test performed to ALS patients."@en ;
                rdfs:label "Walk Test ALS"@en .


###  https://w3id.org/brainteaser/ontology/schema/WalkTestMS
bto:WalkTestMS rdf:type owl:Class ;
               rdfs:subClassOf bto:WalkTest ;
               rdfs:comment "Walk test performed to MS patients."@en ;
               rdfs:label "Walk Test MS"@en .


###  https://w3id.org/brainteaser/ontology/schema/WearableDataMeasurement
bto:WearableDataMeasurement rdf:type owl:Class ;
                            rdfs:subClassOf bto:Activity ;
                            rdfs:comment "Measurements collected by wearables."@en ;
                            rdfs:label "Wearable Data Measurement"@en .


###  https://w3id.org/brainteaser/ontology/schema/WeatherData
bto:WeatherData rdf:type owl:Class ;
                rdfs:subClassOf <http://www.wurvoc.org/vocabularies/om-1.8/Quantity> ,
                                [ rdf:type owl:Restriction ;
                                  owl:onProperty <http://purl.oclc.org/NET/ssnx/ssn#isProducedBy> ;
                                  owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger ;
                                  owl:onClass <http://purl.oclc.org/NET/ssnx/ssn#SensingDevice>
                                ] ;
                rdfs:comment "The different weather information registered by sensing devices."@en ;
                rdfs:label "Weather Data"@en .


###  https://w3id.org/brainteaser/ontology/schema/WindSpeed
bto:WindSpeed rdf:type owl:Class ;
              rdfs:subClassOf bto:WeatherData ;
              rdfs:label "Wind Speed"@en .


#################################################################
#    Individuals
#################################################################

###  http://data.europa.eu/esco/isco/C0
ESCO:C0 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Armed forces occupations include all jobs held by members of the armed forces. Members of the armed forces are those personnel who are currently serving in the armed forces, including auxiliary services, whether on a voluntary or compulsory basis, and who are not free to accept civilian employment and are subject to military discipline. Included are regular members of the army, navy, air force and other military services, as well as conscripts enrolled for military training or other service for a specified period.
Occupations in this major group are classified into the following sub-major groups:
01 Commissioned Armed Forces Officers
02 Non-commissioned Armed Forces Officers
03 Armed Forces Occupations, Other Ranks
Excluded from this group are:
- jobs held by persons in civilian employment of government establishments concerned with defence issues;
- police (other than military police);
- customs inspectors and members of border or other armed civilian services."""@en ;
        rdfs:label "Armed forces occupations"@en .


###  http://data.europa.eu/esco/isco/C01
ESCO:C01 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Commissioned armed forces officers provide leadership and management to organizational units in the armed forces and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes all members of the armed forces holding the rank of second lieutenant (or equivalent) or higher. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level.
Occupations in this sub-major group are classified into the following minor group:
011 Commissioned Armed Forces Officers
Excluded from this group are:
- jobs held by persons in civilian employment of government establishments concerned with defence issues;
- police (other than military police);
- customs inspectors and members of border or other armed civilian services."""@en ;
         rdfs:label "Commissioned armed forces officers"@en ;
         skos:broaderTransitive ESCO:C0 .


###  http://data.europa.eu/esco/isco/C02
ESCO:C02 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Non-commissioned armed forces officers enforce military discipline and supervise the activities of those employed in Sub-major Group 03: Armed Forces Occupations, Other Ranks, and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes members of the armed forces holding ranks such as sergeant, warrant officer and sergeant major. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Occupations in this sub-major group are classified into the following minor group:
021 Non-commissioned Armed Forces Officers
Excluded from this group are:
- jobs held by persons in civilian employment of government establishments concerned with defence issues;
- police (other than military police);
- customs inspectors and members of border or other armed civilian services."""@en ;
         rdfs:label "Non-commissioned armed forces officers"@en ;
         skos:broaderTransitive ESCO:C0 .


###  http://data.europa.eu/esco/isco/C03
ESCO:C03 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Armed forces occupations, other ranks include all conscripted and non-conscripted members of the armed forces except commissioned and non-commissioned officers. They perform specific military tasks and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. Most occupations in this sub-major group require skills at the first ISCO skill level.
Occupations in this sub-major group are classified into the following minor group:
031 Armed Forces Occupations, Other Ranks
Excluded from this group are:
- jobs held by persons in civilian employment of government establishments concerned with defence issues;
- police (other than military police);
- customs inspectors and members of border or other armed civilian services."""@en ;
         rdfs:label "Armed forces occupations, other ranks"@en ;
         skos:broaderTransitive ESCO:C0 .


###  http://data.europa.eu/esco/isco/C1
ESCO:C1 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Managers plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations, or of organizational units within them, and formulate and review their policies, laws, rules and regulations. Competent performance in most occupations in this major group requires skills at the fourth ISCO skill level, except for Sub-major Group 14: Hospitality, Retail and Other Services Managers, for which skills at the third ISCO skill level are generally required.
Tasks performed by managers usually include: formulating and advising on the policy, budgets, laws and regulations of enterprises, governments and other organizational units; establishing objectives and standards and formulating and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise and of its staff; selecting or approving the selection of staff; ensuring compliance with health and safety requirements; planning and directing daily operations; representing and negotiating on behalf of the government, enterprise or organizational unit managed in meetings and other forums.
Occupations in this major group are classified into the following sub-major groups:
11 Chief Executives, Senior Officials and Legislators
12 Administrative and Commercial Managers
13 Production and Specialized Services Managers
14 Hospitality, Retail and Other Services Managers"""@en ;
        rdfs:label "Managers"@en .


###  http://data.europa.eu/esco/isco/C11
ESCO:C11 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Chief executives, senior officials and legislators formulate and review the policies, and plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations with the support of other managers. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level .
Tasks performed by workers in this sub-major group usually include: presiding over or participating in the proceedings of legislative bodies, boards of directors and committees; formulating and advising on the policy budgets, laws and regulations of enterprises, governments and other organizations; establishing objectives for enterprises, government departments or agencies and other organizations; formulating or approving and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise; selecting or approving the selection of senior staff; performing ceremonial duties and representing the enterprise, government, organization or community at official occasions and in meetings, negotiations, conventions and public hearings.
Occupations in this sub-major group are classified into the following minor groups:
111 Legislators and Senior Officials
112 Managing Directors and Chief Executives"""@en ;
         rdfs:label "Chief executives, senior officials and legislators"@en ;
         skos:broaderTransitive ESCO:C1 .


###  http://data.europa.eu/esco/isco/C12
ESCO:C12 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Administrative and commercial managers plan, organize, direct, control and coordinate the financial, administrative, human resource, policy, planning, research and development, advertising, public relations, and sales and marketing activities of enterprises and organizations, or of enterprises that provide such services to other enterprises and organizations. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level
Tasks performed by workers in this sub-major group usually include: formulating and administering policy advice and strategic and financial planning; establishing and directing operational and administrative procedures; implementing, monitoring and evaluating strategies and policies; providing advice to senior managers; directing the development of initiatives for new products, marketing, public relations and advertising campaigns; determining and directing sales activities, product mix and customer service standards; setting prices and credit arrangements; ensuring compliance with relevant legislation, regulations and standards; controlling selection, training and performance of staff; preparing budgets and overseeing financial operations; consulting with the chief executive and with managers of other departments or sections; controlling expenditure and ensuring the efficient use of resources; representing the enterprise or organization in negotiations, and at conventions, seminars, public hearings and forums.
Occupations in this sub-major group are classified into the following minor groups:
121 Business Services and Administration Managers
122 Sales, Marketing and Development Managers"""@en ;
         rdfs:label "Administrative and commercial managers"@en ;
         skos:broaderTransitive ESCO:C1 .


###  http://data.europa.eu/esco/isco/C13
ESCO:C13 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Production and specialized services managers plan, direct and coordinate the production of the goods and the provision of the specialized professional and technical services provided by an enterprise or organization, either as the manager of a department or as the general manager of an enterprise or organization that does not have a hierarchy of managers. They are responsible for manufacturing, mining, construction, logistics, information and communications technology operations for large-scale agricultural, forestry and fisheries operations, and for the provision of health, education, social welfare, banking, insurance and other professional and technical services. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level.
Tasks performed by workers in this sub-major group usually include: planning details of activities in terms of output, services provided, quality, quantity, cost, timeliness and labour requirements; setting standards and objectives; controlling the operation of plant and of procedures; assuring quality of the goods produced and services provided; preparing tenders and contract bids; establishing and managing budgets, monitoring costs, and adjusting activities, procedures and resources to minimize costs; overseeing the acquisition and installation of new plant and equipment; coordinating the implementation of health and safety requirements; planning and directing daily operations; overseeing the selection, training and performance of staff; preparing, or arranging for the preparation of, reports, budgets and forecasts; representing the enterprise or organization in negotiations with other agencies, and at conventions, seminars, public hearings and forums.
Occupations in this sub-major group are classified into the following minor groups:
131 Production Managers in Agriculture, Forestry and Fisheries
132 Manufacturing, Mining, Construction and Distribution Managers
133 Information and Communications Technology Services Managers
134 Professional Services Managers"""@en ;
         rdfs:label "Production and specialised services managers"@en ;
         skos:broaderTransitive ESCO:C1 .


###  http://data.europa.eu/esco/isco/C14
ESCO:C14 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Hospitality, retail and other services managers plan, organize and direct the operations of establishments which provide accommodation, hospitality, retail and other services. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level.
Tasks performed by workers in this sub-major group usually include: planning and organizing special functions, sporting, gaming and entertainment activities and the range and mix of products, stock levels and service standards; promoting and selling goods and services; observing liquor, gaming, health and other laws and regulations; developing and reviewing policies, programmes and procedures concerning customer relations and goods and services provided; promoting facilities for conferences, conventions and trade shows to potential customers; organizing the purchase and maintenance of transport vehicles, equipment and fuel, and transporting goods; controlling the selection, training and supervision of staff; ensuring compliance with occupational health and safety regulations.
Occupations in this sub-major group are classified into the following minor groups:
141 Hotel and Restaurant Managers
142 Retail and Wholesale Trade Managers
143 Other Services Managers"""@en ;
         rdfs:label "Hospitality, retail and other services managers"@en ;
         skos:broaderTransitive ESCO:C1 .


###  http://data.europa.eu/esco/isco/C2
ESCO:C2 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Professionals increase the existing stock of knowledge; apply scientific or artistic concepts and theories; teach about the foregoing in a systematic manner; or engage in any combination of these activities. Competent performance in most occupations in this major group requires skills at the fourth ISCO skill level.
Tasks performed by professionals usually include: conducting analysis and research, and developing concepts, theories and operational methods; advising on or applying existing knowledge related to physical sciences, mathematics, engineering and technology, life sciences, medical and health services, social sciences and humanities; teaching the theory and practice of one or more disciplines at different educational levels; teaching and educating persons with learning difficulties or special needs; providing various business, legal and social services; creating and performing works of art; providing spiritual guidance; preparing scientific papers and reports. Supervision of other workers may be included.
Occupations in this major group are classified into the following sub-major groups:
21 Science and Engineering Professionals
22 Health Professionals
23 Teaching Professionals
24 Business and Administration Professionals
25 Information and Communications Technology Professionals
26 Legal, Social and Cultural Professionals"""@en ;
        rdfs:label "Professionals"@en .


###  http://data.europa.eu/esco/isco/C21
ESCO:C21 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Science and engineering professionals conduct research; improve or develop concepts, theories and operational methods; or apply scientific knowledge relating to fields such as physics, astronomy, meteorology, chemistry, geophysics, geology, biology, ecology, pharmacology, medicine, mathematics, statistics, architecture, engineering, design and technology. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level.
Tasks performed by workers in this sub-major group usually include: conducting research, enlarging, advising on or applying scientific knowledge obtained through the study of structures and properties of physical matter and phenomena, chemical characteristics and processes of various substances, materials and products, all forms of human, animal and plant life and of mathematical and statistical concepts and methods; advising on, designing and directing construction of buildings, towns and traffic systems, or civil engineering and industrial structures, as well as machines and other equipment; advising on and applying mining methods and ensuring their optimum use; surveying land and sea and making maps; studying and advising on technological aspects of particular materials, products and processes, and on efficiency of production and work organization; preparing scientific papers and reports. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
211 Physical and Earth Science Professionals
212 Mathematicians, Actuaries and Statisticians
213 Life Science Professionals
214 Engineering Professionals (excluding Electrotechnology)
215 Electrotechnology Engineers
216 Architects, Planners, Surveyors and Designers"""@en ;
         rdfs:label "Science and engineering professionals"@en ;
         skos:broaderTransitive ESCO:C2 .


###  http://data.europa.eu/esco/isco/C22
ESCO:C22 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Health professionals conduct research,; improve or develop concepts, theories and operational methods; and apply scientific knowledge relating to medicine, nursing, dentistry, veterinary medicine, pharmacy, and promotion of health. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level.
Tasks performed by workers in this sub-major group usually include: conducting research and obtaining scientific knowledge through the study of human and animal disorders and illnesses and ways of treating them; advising on or applying preventive and curative measures, or promoting health; preparing scientific papers and reports. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
221 Medical Doctors
222 Nursing and Midwifery Professionals
223 Traditional and Complementary Medicine Professionals
224 Paramedical Practitioners
225 Veterinarians
226 Other Health Professionals"""@en ;
         rdfs:label "Health professionals"@en ;
         skos:broaderTransitive ESCO:C2 .


###  http://data.europa.eu/esco/isco/C23
ESCO:C23 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Teaching professionals teach the theory and practice of one or more disciplines at different educational levels; conduct research; improve or develop concepts, theories and operational methods pertaining to their particular discipline; and prepare scholarly papers and books. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level.
Tasks performed by workers in this sub-major group usually include: conducting classes, courses, or tutorials at a particular educational level for educational and vocational purposes, including private lessons; conducting adult literacy programmes; teaching and educating persons with learning difficulties or special needs; designing and modifying curricula; inspecting and advising on teaching methods and aids; participating in decisions concerning the organization of teaching and related activities at schools and universities; conducting research in particular subjects to improve or develop concepts, theories or operational methods for application in industrial and other fields; preparing scholarly papers and books. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor group:
231 University and Higher Education Teachers
232 Vocational Education Teachers
233 Secondary Education Teachers
234 Primary School and Early Childhood Teachers
235 Other Teaching Professionals"""@en ;
         rdfs:label "Teaching professionals"@en ;
         skos:broaderTransitive ESCO:C2 .


###  http://data.europa.eu/esco/isco/C24
ESCO:C24 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Business and administration professionals perform analytical, conceptual and practical tasks to provide services in financial matters, human resource development, public relations, marketing and sales in the technical, medical, information and communications technology areas; and conduct reviews of organizational structures, methods and systems as well as quantitative analyses of information affecting investment programmes. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level.
Tasks performed by workers in this sub-major group usually include: collecting, analysing and interpreting information on the financial viability, cost structures and trading effectiveness of organizations; conducting audits, preparing financial statements and controlling treasury systems for organizations; developing and reviewing financial plans and strategies, executing buy and sell orders, and negotiating the purchase and sale of commodities; developing, implementing and evaluating staff recruitment, training and development programmes; researching, developing and implementing marketing and public relations campaigns; studying and developing methods and policies to improve and promote government and business operations and effectiveness; acquiring and updating knowledge of employers’ and competitors’ goods and services, and of market conditions; assessing customers’ needs and explaining and demonstrating goods and services to them.
Occupations in this sub-major group are classified into the following minor group:
241 Finance Professionals
242 Administration Professionals
243 Sales, Marketing and Public Relations Professionals"""@en ;
         rdfs:label "Business and administration professionals"@en ;
         skos:broaderTransitive ESCO:C2 .


###  http://data.europa.eu/esco/isco/C25
ESCO:C25 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Information and communications technology professionals conduct research; plan, design, write, test, provide advice and improve information technology systems, hardware, software and related concepts for specific applications; develop associated documentation including principles, policies and procedures; and design, develop, control, maintain and support databases and other information systems to ensure optimal performance and data integrity and security.
Tasks performed by workers in this sub-major group usually include: researching information technology use in business functions; identifying areas for improvement and researching the theoretical aspects and operational methods for the use of computers; evaluating, planning and designing hardware or software configurations for specific applications including for Internet, Intranet and multimedia systems; designing, writing, testing and maintaining computer programs; designing and developing database architecture and database management systems; developing and implementing security plans and data administration policy, and administering computer networks and related computing environments; analysing, developing, interpreting and evaluating complex system design and architecture specifications, data models and diagrams in the development, configuration and integration of computer systems.
Occupations in this sub-major group are classified into the following minor groups:
251 Software and Applications Developers and Analysts
252 Database and Network Professionals"""@en ;
         rdfs:label "Information and communications technology professionals"@en ;
         skos:broaderTransitive ESCO:C2 .


###  http://data.europa.eu/esco/isco/C26
ESCO:C26 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Legal, social and cultural professionals conduct research; improve or develop concepts, theories and operational methods; or apply knowledge relating to the law, storage and retrieval of information and artefacts, psychology, social welfare, politics, economics, history, religion, languages, sociology, other social sciences, and arts and entertainment. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level.
Tasks performed by workers in this sub-major group usually include: conducting research on legal problems; drafting laws and regulations; advising clients on legal cases; pleading and conducting cases in a court of law; presiding over judicial proceedings in a court of law; developing and maintaining library and gallery collections of archives; conducting research, improving or developing concepts, theories and operational methods or applying knowledge relating to the field of social sciences; conceiving, creating and performing in literary and artistic works; interpreting and communicating news, ideas, impressions and facts.
Occupations in this sub-major group are classified into the following minor groups:
261 Legal Professionals
262 Librarians, Archivists and Curators
263 Social and Religious Professionals
264 Authors, Journalists and Linguists
265 Creative and Performing Artists"""@en ;
         rdfs:label "Legal, social and cultural professionals"@en ;
         skos:broaderTransitive ESCO:C2 .


###  http://data.europa.eu/esco/isco/C3
ESCO:C3 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Technicians and associate professionals perform technical and related tasks connected with research and the application of scientific or artistic concepts and operational methods, and government or business regulations. Competent performance in most occupations in this major group requires skills at the third ISCO skill level.
Tasks performed by technicians and associate professionals usually include: undertaking and carrying out technical work connected with research and the application of concepts and operational methods in the fields of physical sciences including engineering and technology, life sciences including the medical profession, and social sciences and humanities; initiating and carrying out various technical services related to trade, finance and administration including administration of government laws and regulations, and to social work; providing technical support for the arts and entertainment; participating in sporting activities; executing some religious tasks. Supervision of other workers may be included.
Occupations in this major group are classified into the following sub-major groups:
31 Science and Engineering Associate Professionals
32 Health Associate Professionals
33 Business and Administration Associate Professionals
34 Legal, Social, Cultural and Related Associate Professionals
35 Information and Communications Technicians"""@en ;
        rdfs:label "Technicians and associate professionals"@en .


###  http://data.europa.eu/esco/isco/C31
ESCO:C31 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Science and engineering associate professionals perform technical tasks connected with research and operational methods in science and engineering. They supervise and control technical and operational aspects of mining, manufacturing, construction and other engineering operations, and operate technical equipment including aircraft and ships. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level.
Tasks performed by workers in this sub-major group usually include: setting up, monitoring and operating instruments and equipment, conducting and monitoring experiments and tests of systems; collecting and testing samples; recording observations and analysing data; preparing, revising and interpreting technical drawings and diagrams; coordinating, supervising, controlling and scheduling the activities of other workers; operating and monitoring switchboards, computerized control systems, and multi-function process control machinery; performing technical functions to ensure safe and efficient movement and operations in ships, aircraft and other equipment.
Occupations in this sub-major group are classified into the following minor groups:
311 Physical and Engineering Science Technicians
312 Mining, Manufacturing and Construction Supervisors
313 Process Control Technicians
314 Life Science Technicians and Related Associate Professionals
315 Ship and Aircraft Controllers and Technicians"""@en ;
         rdfs:label "Science and engineering associate professionals"@en ;
         skos:broaderTransitive ESCO:C3 .


###  http://data.europa.eu/esco/isco/C32
ESCO:C32 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Health associate professionals perform technical and practical tasks to support diagnosis and treatment of illness, disease, injuries and impairments in humans and animals, and to support implementation of health care, treatment and referral plans usually established by medical, veterinary, nursing and other health professionals. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level.
Tasks performed by workers in the sub-major group usually include: testing and operating medical imaging equipment and administering radiation therapy; performing clinical tests on specimens of bodily fluids and tissues; preparing medications and other pharmaceutical compounds under the guidance of pharmacists; designing, fitting, servicing and repairing medical and dental devices and appliances; providing nursing and personal care and midwifery support services; using herbal and other therapies based on theories, beliefs and experiences originating in specific cultures.
Occupations in this sub-major group are classified into the following minor groups:
321 Medical and Pharmaceutical Technicians
322 Nursing and Midwifery Associate Professionals
323 Traditional and Complementary Medicine Associate Professionals
324 Veterinary Technicians and Assistants
325 Other Health Associate Professionals"""@en ;
         rdfs:label "Health associate professionals"@en ;
         skos:broaderTransitive ESCO:C3 .


###  http://data.europa.eu/esco/isco/C33
ESCO:C33 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Business and administration associate professionals perform mostly technical tasks connected with the practical application of knowledge relating to financial accounting and transaction matters, mathematical calculations, human resource development, selling and buying financial instruments, specialized secretarial tasks, and enforcing or applying government rules. Also included are workers who provide business services such as customs clearance, conference planning, job placements, buying and selling real estate or bulk commodities, and serving as agents for performers such as athletes and artists. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level.
Tasks performed by workers in this sub-major group usually include recording and transmitting buy and sell orders for securities, stocks, bonds or other financial instruments and for foreign exchange for future or immediate delivery; submitting credit and loan applications to management with recommendations for approval or rejection; approving or rejecting applications within authorized limits ensuring that credit standards of the institution are respected; maintaining complete records of all financial transactions of an undertaking according to general bookkeeping principles, with guidance from accountants; assisting in planning and performing mathematical, statistical, actuarial, accounting and related calculations; selling and buying financial instruments.
Occupations in this sub-major group are classified into the following minor groups:
331 Financial and Mathematical Associate Professionals
332 Sales and Purchasing Agents and Brokers
333 Business Services Agents
334 Administrative and Specialized Secretaries
335 Government Regulatory Associate Professionals"""@en ;
         rdfs:label "Business and administration associate professionals"@en ;
         skos:broaderTransitive ESCO:C3 .


###  http://data.europa.eu/esco/isco/C34
ESCO:C34 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Legal, social, cultural and related associate professionals perform technical tasks connected with the practical application of knowledge relating to legal services, social work, culture, food preparation, sport and religion. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level.
Tasks performed by workers in this sub-major group usually include: providing technical and practical services and support functions in legal processes and investigations, social and community assistance programmes, and religious and cultural activities; participating and adjudicating in sporting events; developing and delivering sports coaching, fitness and recreational programmes; combining creative and technical skills in a variety of artistic, cultural and culinary activities; creating dishes and menus and overseeing the preparation of meals.
Occupations in this sub-major group are classified into the following minor groups:
341 Legal, Social and Religious Associate Professionals
342 Sports and Fitness Workers
343 Artistic, Cultural and Culinary Associate Professionals"""@en ;
         rdfs:label "Legal, social, cultural and related associate professionals"@en ;
         skos:broaderTransitive ESCO:C3 .


###  http://data.europa.eu/esco/isco/C35
ESCO:C35 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Information and communications technicians provide support for the day-to-day running of computer systems, communications systems and networks, and perform technical tasks related to telecommunications, broadcast image and sound as well as other types of telecommunications signals on land, sea or in aircraft. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level.
Tasks performed by workers in this sub-major group usually include: providing assistance to information and communications systems users; installing new programs and equipment; establishing, operating and maintaining network and other data communications systems; installing, monitoring and supporting Internet and Intranet websites or web server hardware or software; modifying web pages; and performing web server backup and recovery operations; controlling equipment to record sound, edit and mix image and sound recordings; controlling and maintaining transmitting and broadcast systems and satellite systems for radio and television programmes; controlling and maintaining radio communications systems, satellite services and multiplex systems on land, sea or in aircraft; providing technical assistance connected with research and development of computer systems and telecommunications equipment, or testing prototypes; designing and preparing blueprints of circuitry according to the specifications given; providing technical supervision of the manufacture, utilization, maintenance and repair of telecommunications systems.
Occupations in this sub-major group are classified into the following minor groups:
351 Information and Communications Technology Operations and User Support Technicians
352 Telecommunications and Broadcasting Technicians"""@en ;
         rdfs:label "Information and communications technicians"@en ;
         skos:broaderTransitive ESCO:C3 .


###  http://data.europa.eu/esco/isco/C4
ESCO:C4 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Clerical support workers record, organize, store, compute and retrieve information, and perform a number of clerical duties in connection with money-handling operations, travel arrangements, requests for information, and appointments. Competent performance in most occupations in this major group requires skills at the second ISCO skill level.
Tasks performed by clerical support workers usually include: stenography, typing, and operating word processors and other office machines; entering data into computers; carrying out secretarial duties; recording and computing numerical data; keeping records relating to stocks, production and transport; keeping records relating to passenger and freight transport; carrying out clerical duties in libraries; filing documents; carrying out duties in connection with mail services; preparing and checking material for printing; assisting persons who cannot read or write with correspondence; performing money-handling operations; dealing with travel arrangements; supplying information requested by clients and making appointments; operating a telephone switchboard. Supervision of other workers may be included.
Occupations in this major group are classified into the following sub-major groups:
41 General and Keyboard Clerks
42 Customer Services Clerks
43 Numerical and Material Recording Clerks
44 Other Clerical Support Workers"""@en ;
        rdfs:label "Clerical support workers"@en .


###  http://data.europa.eu/esco/isco/C41
ESCO:C41 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """General and keyboard clerks record, organize, store and retrieve information and perform a wide range of clerical and administrative tasks according to established procedures. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: recording, preparing, sorting, classifying and filing information; sorting, opening and sending mail; preparing reports and correspondence of a routine nature; photocopying and faxing documents; operating personal computers, word processors or typewriters to record, input and process text and data; proofreading and correcting copy; preparing invoices and checking figures.
Occupations in this sub-major group are classified into the following minor groups:
411 General Office Clerks
412 Secretaries (general)
413 Keyboard Operators"""@en ;
         rdfs:label "General and keyboard clerks"@en ;
         skos:broaderTransitive ESCO:C4 .


###  http://data.europa.eu/esco/isco/C42
ESCO:C42 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Customer services clerks deal with clients in connection with money-handling operations, travel arrangements, requests for information, making appointments, operating telephone switchboards, and interviewing for surveys or to complete applications for eligibility for services. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: performing money-handling operations in banks, post offices, betting and gambling establishments, or dealing with travel arrangements; supplying information requested by clients and making appointments; operating telephone switchboards; greeting and receiving visitors; interviewing survey respondents; interviewing applicants for services.
Occupations in this sub-major group are classified into the following minor groups:
421 Tellers, Money Collectors and Related Clerks
422 Client Information Workers"""@en ;
         rdfs:label "Customer services clerks"@en ;
         skos:broaderTransitive ESCO:C4 .


###  http://data.europa.eu/esco/isco/C43
ESCO:C43 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Numerical and material recording clerks obtain, compile and compute accounting, bookkeeping, statistical, financial and other numerical data, and take charge of cash transactions incidental to business matters. Some occupations classified here keep records of goods produced, purchased, stocked and dispatched, and of materials needed at specified production dates, or keep records of operational aspects and coordinate the timing of passenger and freight transport. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: helping with accounting and bookkeeping records and computations; calculating unit production costs; calculating wages and in some cases preparing wage packets and paying wages; taking charge of cash transactions incidental to the business; obtaining, compiling and computing statistical or actuarial data; performing clerical tasks relating to the financial transactions of an insurance establishment, bank or similar establishment; recording produced, stocked, ordered and dispatched goods; recording production materials received, put into stock or issued; computing quantities of the production materials required at specified dates and helping with preparation and checking of production operation schedules; keeping records of operational aspects and coordinating the timing of passenger and freight transport.
Occupations in this sub-major group are classified into the following minor groups:
431 Numerical Clerks
432 Material Recording and Transport Clerks"""@en ;
         rdfs:label "Numerical and material recording clerks"@en ;
         skos:broaderTransitive ESCO:C4 .


###  http://data.europa.eu/esco/isco/C44
ESCO:C44 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Other clerical support workers sort and deliver mail, file documents, prepare information for processing, maintain personnel records, check material for consistency with original source material, assist persons who cannot read or write, and perform various other specialized clerical duties. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: recording information regarding acquisition, issue and return of library books; classifying and filing various documents and other records; maintaining personnel records; sorting, recording and delivering mail from post offices, as well as from or within an enterprise; coding; correcting proofs; performing a range of miscellaneous clerical duties; writing on behalf of persons who are unable to read or write.
Occupations in this sub-major group are classified into the following minor group:
441 Other Clerical Support Workers"""@en ;
         rdfs:label "Other clerical support workers"@en ;
         skos:broaderTransitive ESCO:C4 .


###  http://data.europa.eu/esco/isco/C5
ESCO:C5 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Services and sales workers provide personal and protective services related to travel, housekeeping, catering, personal care, protection against fire and unlawful acts; or demonstrate and sell goods in wholesale or retail shops and similar establishments, as well as at stalls and on markets. Competent performance in most occupations in this major group requires skills at the second ISCO skill level.
Tasks performed by services and sales workers usually include: organizing and providing services during travel; housekeeping; preparing and serving of food and beverages; caring for children; providing personal and basic health care at homes or in institutions, as well as hairdressing, beauty treatment and companionship; telling fortunes; embalming and arranging funerals; providing security services and protecting individuals and property against fire and unlawful acts; enforcing of law and order; posing as models for advertising, artistic creation and display of goods; selling goods in wholesale or retail establishments, as well as at stalls and on markets; and demonstrating goods to potential customers. Supervision of other workers may be included.
Occupations in this major group are classified into the following sub-major groups:
51 Personal Services Workers
52 Sales Workers
53 Personal Care Workers
54 Protective Services Workers"""@en ;
        rdfs:label "Service and sales workers"@en .


###  http://data.europa.eu/esco/isco/C51
ESCO:C51 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Personal services workers provide personal services related to travel, housekeeping, catering and hospitality, hairdressing and beauty treatment, animal care grooming and training, companionship and other services of a personal nature. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: organizing and providing services in connection with travel and sightseeing; housekeeping; preparing and serving food and beverages; hairdressing and beauty treatment; telling fortunes; embalming and arranging funerals; grooming, caring for and training animals; teaching people to drive motor vehicles; providing companionship and other personal services. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
511 Travel Attendants, Conductors and Guides
512 Cooks
513 Waiters and Bartenders
514 Hairdressers, Beauticians and Related Workers
515 Building and Housekeeping Supervisors
516 Other Personal Services Workers"""@en ;
         rdfs:label "Personal service workers"@en ;
         skos:broaderTransitive ESCO:C5 .


###  http://data.europa.eu/esco/isco/C52
ESCO:C52 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Sales workers sell and demonstrate goods in wholesale or retail shops, at stalls and markets, door-to-door, via telephone or customer contact centres. They may record and accept payment for goods and services purchased, and may operate small retail outlets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: selling goods in wholesale or retail establishments, at street or market stalls, door-to-door, via telephone or customer contact centres; demonstrating and displaying goods to potential customers; selling and serving food for immediate consumption at counters and in the street; buying or contracting a regular supply of products to be sold; stacking and displaying goods for sale and wrapping or packing goods sold; determining product mix, stock and price levels for goods to be sold; operating cash registers, optical price scanners, computers or other equipment to record and accept payment for the purchase of goods and services. Supervision of other workers may be required in some occupations classified here.
Occupations in this sub-major group are classified into the following minor groups:
521 Street and Market Salespersons
522 Shop Salespersons
523 Cashiers and Ticket Clerks
524 Other Sales Workers"""@en ;
         rdfs:label "Sales workers"@en ;
         skos:broaderTransitive ESCO:C5 .


###  http://data.europa.eu/esco/isco/C53
ESCO:C53 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Personal care workers provide care, supervision and assistance for children, patients and elderly, convalescent or disabled persons in institutional and residential settings. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: assisting with mobility, washing and other personal needs; assisting children individually to learn social skills; supervising and participating in activities that enhance children’s physical, social, emotional and intellectual development; observing and reporting concerns to appropriate health or social service workers.
Occupations in this sub-major group are classified into the following minor groups:
531 Child Care Workers and Teachers’ Aides
532 Personal Care Workers in Health Services"""@en ;
         rdfs:label "Personal care workers"@en ;
         skos:broaderTransitive ESCO:C5 .


###  http://data.europa.eu/esco/isco/C54
ESCO:C54 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Protective services workers protect individuals and property against fire and other hazards, maintain law and order and enforce laws and regulations. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: preventing, fighting and extinguishing fires; rescuing people from burning buildings and accident sites and those trapped in dangerous situations; maintaining law and order, enforcing laws and regulations, patrolling public areas and arresting suspected offenders; directing traffic and assuming authority in the event of accidents; watching over and maintaining order among inmates of prisons, reformatories or penitentiaries; patrolling or monitoring premises to guard property against theft and vandalism, controlling access to establishments and maintaining order and enforcing regulations at public events and within establishments. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor group:
541 Protective Services Workers"""@en ;
         rdfs:label "Protective services workers"@en ;
         skos:broaderTransitive ESCO:C5 .


###  http://data.europa.eu/esco/isco/C6
ESCO:C6 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Skilled agricultural, forestry and fishery workers grow and harvest field or tree and shrub crops; gather wild fruits and plants; breed, tend or hunt animals; produce a variety of animal husbandry products; cultivate, conserve and exploit forests; breed or catch fish; and cultivate or gather other forms of aquatic life in order to provide food, shelter and income for themselves and their households. Competent performance in most occupations in this major group requires skills at the second ISCO skill level.
Tasks performed by skilled agricultural, forestry and fishery workers usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; gathering wild fruits and plants; breeding, raising, tending or hunting animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; cultivating, conserving and exploiting forests; breeding or catching fish; cultivating or gathering other forms of aquatic life; storing and carrying out some basic processing of their produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included.
Occupations in this major group are classified into the following sub-major groups:
61 Market-oriented Skilled Agricultural Workers
62 Market-oriented Skilled Forestry, Fishery and Hunting Workers
63 Subsistence Farmers, Fishers, Hunters and Gatherers"""@en ;
        rdfs:label "Skilled agricultural, forestry and fishery workers"@en .


###  http://data.europa.eu/esco/isco/C61
ESCO:C61 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Market-oriented skilled agricultural workers plan, organize and perform farming operations to grow and harvest field or tree and shrub crops; and to produce a variety of animals and animal products for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; raising, breeding and tending animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; storing and carrying out some processing of produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
611 Market Gardeners and Crop growers
612 Animal Producers
613 Mixed Crop and Animal Producers"""@en ;
         rdfs:label "Market-oriented skilled agricultural workers"@en ;
         skos:broaderTransitive ESCO:C6 .


###  http://data.europa.eu/esco/isco/C62
ESCO:C62 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Market-oriented skilled forestry, fishery and hunting workers plan, organize and perform operations to cultivate, conserve and exploit natural and plantation forests; breed and raise fish; harvest and catch fish; and hunt and trap animals, for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: renting or investing in equipment and machinery and purchasing supplies; planning and undertaking forestry, aquaculture, fishery and hunting operations; maintaining buildings, tanks, machinery and other equipment; delivering or marketing products; supervising and training other workers.
Occupations in this sub-major group are classified into the following minor groups:
621 Forestry and Related Workers
622 Fishery Workers, Hunters and Trappers"""@en ;
         rdfs:label "Market-oriented skilled forestry, fishery and hunting workers"@en ;
         skos:broaderTransitive ESCO:C6 .


###  http://data.europa.eu/esco/isco/C63
ESCO:C63 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Subsistence farmers, fishers, hunters and gatherers grow and harvest field or tree and shrub crops, vegetables and fruit; gather wild fruits, medicinal and other plants; tend or hunt animals; catch fish and gather various forms of aquatic life in order to provide food, shelter and, in some cases, a minimum of cash income for themselves and their households. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, tending and harvesting field crops; growing vegetables, fruit and other tree and shrub crops; gathering wild fruits, medicinal and other plants; breeding, tending and feeding animals and poultry mainly to obtain meat, eggs, milk, hair, skin or other products; hunting or trapping animals; catching fish and gathering other forms of aquatic life; fetching water and gathering firewood; storing produce for later use and carrying out some processing of produce; building and maintaining houses and other shelters; making tools, clothes and utensils for use by the household; selling or bartering some products at local markets.
Occupations in this sub-major group are classified into the following minor groups:
631 Subsistence Crop Farmers
632 Subsistence Livestock Farmers
633 Subsistence Mixed Crop and Livestock Farmers
634 Subsistence Fishers, Hunters, Trappers and Gatherers"""@en ;
         rdfs:label "Subsistence farmers, fishers, hunters and gatherers"@en ;
         skos:broaderTransitive ESCO:C6 .


###  http://data.europa.eu/esco/isco/C7
ESCO:C7 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Craft and related trades workers apply specific technical and practical knowledge and skills to construct and maintain buildings; form metal; erect metal structures; set machine tools or make, fit, maintain and repair machinery, equipment or tools; carry out printing work; and produce or process foodstuffs, textiles, wooden, metal and other articles, including handicraft goods. Competent performance in most occupations in this major group requires skills at the second ISCO skill level.
The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of all stages of the production process, the materials and tools used, and the nature and purpose of the final product.
Tasks performed by craft and related trades workers usually include: constructing, maintaining and repairing buildings and other structures; casting, welding and shaping metal; installing and erecting heavy metal structures, tackle and related equipment; making machinery, tools, equipment and other metal articles; setting for operators, or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, engines, vehicles, electrical and electronic instruments and other equipment; making precision instruments, jewellery, household and other precious metal articles, pottery, glass and related products; producing handicrafts; executing printing work; producing and processing foodstuffs and various articles made of wood, textiles, leather and related materials. Supervision of other workers may be included. Self-employed craft and related trades workers, who operate their own businesses either independently or with assistance from a small number of others, may also perform a range of tasks associated with management of the business, account and record keeping and client service, although such tasks would not normally comprise the major component of the work.
Occupations in this major group are classified into the following sub-major groups:
71 Building and Related Trades Workers (excluding electricians)
72 Metal, Machinery and Related Trades Workers
73 Handicraft and Printing Workers
74 Electrical and Electronics Trades Workers
75 Food Processing, Woodworking, Garment and Other Craft and Related Trades Workers"""@en ;
        rdfs:label "Craft and related trades workers"@en .


###  http://data.europa.eu/esco/isco/C71
ESCO:C71 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Building and related trades workers construct, maintain and repair buildings; erect and repair foundations, walls and structures of brick, stone and similar materials; shape and finish stone for building and other purposes. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, the materials and tools used, and the nature and purpose of the final product.
Tasks performed by workers in this sub-major group usually include: constructing, maintaining and repairing buildings and other structures, using traditional and/or modern building techniques; constructing and repairing foundations, walls and structures of brick, stone and similar materials; breaking quarried stone into slabs or blocks; cutting, shaping and finishing stone for building, ornamental, monumental and other purposes; erecting reinforced concrete frameworks and structures as well as finishing and repairing cement surfaces; cutting, shaping, assembling and maintaining wooden structures and fittings; performing miscellaneous construction and building maintenance tasks. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
711 Building Frame and Related Trades Workers
712 Building Finishers and Related Trades Workers
713 Painters, Building Structure Cleaners and Related Trades Workers"""@en ;
         rdfs:label "Building and related trades workers, excluding electricians"@en ;
         skos:broaderTransitive ESCO:C7 .


###  http://data.europa.eu/esco/isco/C72
ESCO:C72 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Metal, machinery and related trades workers cast, weld, forge and, by other methods, form metal; erect, maintain and repair heavy metal structures; engage in machine-tool setting as well as in fitting, maintaining and repairing machinery including engines and vehicles; or they produce tools and various non-precious metal articles. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product
Tasks performed by workers in this sub-major group usually include: making moulds and cores for casting metal; casting, welding and shaping metal; installing, erecting, maintaining and repairing heavy metal structures, tackle and related equipment; forging and forming steel and other non-precious metals to make and repair machinery, tools, equipment and other articles; setting for operators or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, including engines and vehicles. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
721 Sheet and Structural Metal Workers, Moulders and Welders, and Related Workers
722 Blacksmiths, Toolmakers and Related Trades Workers
723 Machinery Mechanics and Repairers"""@en ;
         rdfs:label "Metal, machinery and related trades workers"@en ;
         skos:broaderTransitive ESCO:C7 .


###  http://data.europa.eu/esco/isco/C73
ESCO:C73 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Handicraft and printing workers combine artistic and manual skills to design, produce, maintain and decorate precision instruments, musical instruments, jewellery and other precious metals, pottery, porcelain and glassware, items made of wood or textile, leather or related materials, and printed products such as books, newspapers and magazines. They apply traditional and/or recently developed techniques to carve, mould, assemble, weave and decorate various articles; to compose and set type prior to printing; to set up and operate printing presses; to bind and finish printed products; and to prepare stencils and operate screen printing equipment. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
The work may be carried out by hand or involve the use of hand tools and hand-held power tools, and in some cases the set-up and operation of machinery and machine tools. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product.
Tasks performed by workers in this sub-major group usually include: making and repairing nautical, meteorological, optical and other precision instruments and equipment; making and repairing musical instruments; making jewellery and precious metalware; making pottery, porcelain ware, ceramics and glassware; painting and decorating various articles; producing handicraft articles in wood or textile, leather and related materials; performing printing or book-binding tasks. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
731 Handicraft Workers
732 Printing Trades Workers"""@en ;
         rdfs:label "Handicraft and printing workers"@en ;
         skos:broaderTransitive ESCO:C7 .


###  http://data.europa.eu/esco/isco/C74
ESCO:C74 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Electrical and electronics trades workers install, fit and maintain electrical wiring systems and machinery and other electrical apparatus, electrical transmission and supply lines and cables, and electronic and telecommunications equipment and systems. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product.
Tasks performed by workers in this sub-major group usually include: installing, maintaining, fitting and adjusting electrical and electronic wiring systems, machinery and equipment; examining blueprints, wiring diagrams and specifications to determine sequences and methods of operation; inspecting and testing electrical and electronic systems, equipment, cables and machinery to identify hazards, defects and the need for adjustment or repair; installing, maintaining and repairing electrical and telecommunications transmission lines; joining electrical, telecommunications and data cables; maintaining, troubleshooting, fitting, adjusting, testing and repairing electronic equipment such as commercial and office machines, electronic instruments and control systems, computers, and telecommunications and data transmission equipment.
Occupations in this sub-major group are classified into the following minor groups:
741 Electrical Equipment Installers and Repairers
742 Electronics and Telecommunications Installers and Repairers"""@en ;
         rdfs:label "Electrical and electronic trades workers"@en ;
         skos:broaderTransitive ESCO:C7 .


###  http://data.europa.eu/esco/isco/C75
ESCO:C75 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Food processing, woodworking, garment and other craft and related trades workers treat and process agricultural and fisheries raw materials into food and other products, and produce and repair goods made of wood, textiles, fur, leather or other materials. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product.
Tasks performed by workers in this sub-major group usually include: treating and processing meat, fish, grain, fruit, vegetables and related materials into food stuffs, and tobacco into tobacco products; tasting and grading food products and beverages; treating and processing natural fibres, skins and hides; making and repairing furniture and other goods made of wood; preparing hides, skins and pelts for further use; making and repairing textiles, garments, hats, shoes and related products. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
751 Food Processing and Related Trades Workers
752 Wood Treaters, Cabinet-makers and Related Trades Workers
753 Garment and Related Trades Workers
754 Other Craft and Related Workers"""@en ;
         rdfs:label "Food processing, wood working, garment and other craft and related trades workers"@en ;
         skos:broaderTransitive ESCO:C7 .


###  http://data.europa.eu/esco/isco/C8
ESCO:C8 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Plant and machine operators and assemblers operate and monitor industrial and agricultural machinery and equipment on the spot or by remote control; drive and operate trains, motor vehicles and mobile machinery and equipment; or assemble products from component parts according to strict specifications and procedures. Competent performance in most occupations in this major group requires skills at the second ISCO skill level.
The work mainly calls for experience with and an understanding of industrial and agricultural machinery and equipment, as well as an ability to cope with machine-paced operations and to adapt to technological innovations.
Tasks performed by plant and machine operators and assemblers usually include: operating and monitoring mining or other industrial machinery and equipment for processing metal, minerals, glass, ceramics, wood, paper or chemicals; operating and monitoring machinery and equipment used to produce articles made of metal, minerals, chemicals, rubber, plastics, wood, paper, textiles, fur or leather, and which process foodstuffs and related products; driving and operating trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; and assembling products from component parts according to strict specifications and procedures. Supervision of other workers may be included.
Occupations in this major group are classified into the following sub-major groups:
81 Stationary Plant and Machine Operators
82 Assemblers
83 Drivers and Mobile Plant Operators"""@en ;
        rdfs:label "Plant and machine operators and assemblers"@en .


###  http://data.europa.eu/esco/isco/C81
ESCO:C81 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Stationary plant and machine operators monitor and operate stationary industrial plant, machinery and equipment, or for which mobility is not an integral part of operation. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
The work mainly calls for experience with and an understanding of the industrial plant, machinery or equipment being operated and monitored. Ability to cope with machine-paced operations and to adapt to innovations in machinery and equipment are often required.
Tasks performed by workers in this sub-major group usually include: setting up, operating and monitoring a variety of stationary plant and machinery; detecting malfunctions and taking corrective action; examining outputs for defects and conformity with specifications and adjusting machine settings accordingly; performing maintenance, repairs and cleaning; recording data and maintaining production records. Supervision of other workers may be included.
Occupations in this sub-major group are classified into the following minor groups:
811 Mining and Mineral Processing Plant Operators
812 Metal Processing and Finishing Plant Operators
813 Chemical and Photographic Products Plant and Machine Operators
814 Rubber, Plastic and Paper Products Machine Operators
815 Textile, Fur and Leather Products Machine Operators
816 Food and Related Products Machine Operators
817 Wood Processing and Papermaking Plant Operators
818 Other Stationary Plant and Machine Operators"""@en ;
         rdfs:label "Stationary plant and machine operators"@en ;
         skos:broaderTransitive ESCO:C8 .


###  http://data.europa.eu/esco/isco/C82
ESCO:C82 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Assemblers assemble prefabricated parts or components to form subassemblies, products and equipment, according to procedures strictly laid down. The products worked on may be moved from one worker to the next along assembly lines. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: assembling components into various types of product and equipment, according to strictly laid down procedures; reviewing work orders, specifications, diagrams and drawings to determine materials needed and assembly instructions; recording production and operational data on specified forms; inspecting and testing completed components and assemblies, wiring installations and circuits; rejecting faulty assemblies and components.
Occupations in this sub-major group are classified into the following minor group:
821 Assemblers"""@en ;
         rdfs:label "Assemblers"@en ;
         skos:broaderTransitive ESCO:C8 .


###  http://data.europa.eu/esco/isco/C83
ESCO:C83 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Drivers and mobile plant operators drive and tend trains and motor vehicles, or drive, operate and monitor industrial and agricultural machinery and equipment, or execute deck duties on board ship and other water-borne craft. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level.
Tasks performed by workers in this sub-major group usually include: driving and tending trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; carrying out deck duties on board ship and other water-borne craft.
Occupations in this sub-major group are classified into the following minor groups:
831 Locomotive Engine Drivers and Related Workers
832 Car, Van and Motorcycle Drivers
833 Heavy Truck and Bus Drivers
834 Mobile Plant Operators
835 Ships’ Deck Crews and Related Workers"""@en ;
         rdfs:label "Drivers and mobile plant operators"@en ;
         skos:broaderTransitive ESCO:C8 .


###  http://data.europa.eu/esco/isco/C9
ESCO:C9 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:Occupation ;
        rdfs:comment """Elementary occupations involve the performance of simple and routine tasks which may require the use of hand-held tools and considerable physical effort. Most occupations in this major group require skills at the first ISCO skill level.
Tasks performed by workers in elementary occupations usually include: cleaning, restocking supplies and performing basic maintenance in apartments, houses, kitchens, hotels, offices and other buildings; washing cars and windows; helping in kitchens and performing simple tasks in food preparation; delivering messages or goods; carrying luggage and handling baggage and freight; stocking vending-machines or reading and emptying meters; collecting and sorting refuse; sweeping streets and similar places; performing various simple farming, fishing, hunting or trapping tasks; performing simple tasks connected with mining, construction and manufacturing including product-sorting; packing and unpacking produce by hand, and filling shelves; providing various street services; pedalling or hand-guiding vehicles to transport passengers and goods; driving animal-drawn vehicles or machinery. Supervision of other workers may be included.
Occupations in this major group are classified into the following sub-major groups:
91 Cleaners and Helpers
92 Agricultural, Forestry and Fishery Labourers
93 Labourers in Mining, Construction, Manufacturing and Transport
94 Food Preparation Assistants
95 Street and Related Sales and Services Workers
96 Refuse Workers and Other Elementary Workers"""@en ;
        rdfs:label "Elementary occupations"@en .


###  http://data.europa.eu/esco/isco/C91
ESCO:C91 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Cleaners and helpers perform various tasks in private households, hotels, offices, hospitals and other establishments, as well as in aircraft, trains, coaches, trams and similar vehicles, in order to keep the interiors and fixtures clean, and launder and press garments and textiles by hand. Most occupations in this sub-major group require skills at the first ISCO skill level.
Tasks performed by workers in this sub-major group usually include: sweeping or vacuum cleaning; washing and polishing floors, furniture and other objects; taking care of linen and bedmaking; helping with preparation of meals and cleaning in kitchens; washing and cleaning cars and windows; pressing or laundering garments and textiles by hand.
Occupations in this sub-major group are classified into the following minor groups:
911 Domestic, Hotel and Office Cleaners and Helpers
912 Vehicle, Window, Laundry and Other Hand Cleaning Workers""" ;
         rdfs:label "Cleaners and helpers" ;
         skos:broaderTransitive ESCO:C9 .


###  http://data.europa.eu/esco/isco/C92
ESCO:C92 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Agricultural, forestry and fishery labourers perform simple and routine tasks in the production of crops and livestock, cultivation and maintenance of gardens and parks, exploitation and conservation of forests, and conduct of aquaculture and fisheries operations. Most occupations in this sub-major group require skills at the first ISCO skill level.
Tasks performed by workers in this sub-major group usually include: digging, raking and shovelling using hand tools; loading, unloading and stacking supplies, produce and other materials; watering, thinning, weeding and tending crops by hand or using hand tools; planting, harvesting, picking and collecting produce by hand; feeding, watering and cleaning animals and keeping their quarters clean; monitoring livestock and reporting on their condition; preparing and operating nets, lines and other fishing tackle and deck equipment; grading, sorting, bunching and packing produce into containers; performing minor repairs on fixtures, buildings, equipment, vessels and fences.
Occupations in this sub-major group are classified into the following minor group:
921 Agricultural, Forestry and Fishery Labourers"""@en ;
         rdfs:label "Agricultural, forestry and fishery labourers"@en ;
         skos:broaderTransitive ESCO:C9 .


###  http://data.europa.eu/esco/isco/C93
ESCO:C93 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Labourers in mining, construction, manufacturing and transport perform simple and routine manual tasks in mining, quarrying, civil engineering, building, manufacturing, transport and storage operations, and operate human-powered and animal-drawn vehicles and machinery. Most occupations in this sub-major group require skills at the first ISCO skill level.
Task performed by workers in this sub-major group usually include: digging holes and spreading excavated materials, sand, soil and gravel using hand-held tools; sorting, loading, unloading, moving, stacking and storing materials, equipment, products, supplies, baggage and cargo by hand; cleaning machinery, equipment, tools and work sites; packing and unpacking material and products and filling containers and shelves with products by hand; operating human-powered and animal-drawn vehicles and machinery.
Occupations in this sub-major group are classified into the following minor groups:
931 Mining and Construction Labourers
932 Manufacturing Labourers
933 Transport and Storage Labourers"""@en ;
         rdfs:label "Labourers in mining, construction, manufacturing and transport"@en ;
         skos:broaderTransitive ESCO:C9 .


###  http://data.europa.eu/esco/isco/C94
ESCO:C94 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Food preparation assistants prepare and cook to order a small variety of pre-cooked food or beverages, clear tables, clean kitchen areas and wash dishes. Most occupations in this sub-major group require skills at the first ISCO skill level.
Tasks performed by workers in this sub-major group usually include: preparing simple or pre-prepared foods and beverages such as sandwiches, pizzas, fish and chips, salads and coffee; washing, cutting, measuring and mixing foods for cooking; operating cooking equipment such as grills, microwaves and deep-fat fryers; cleaning kitchens, food preparation areas and service areas; cleaning cooking and general utensils used in kitchens and restaurants.
Occupations in this sub-major group are classified into the following minor group:
941 Food Preparation Assistants"""@en ;
         rdfs:label "Food preparation assistants"@en ;
         skos:broaderTransitive ESCO:C9 .


###  http://data.europa.eu/esco/isco/C95
ESCO:C95 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Street and related sales and services workers sell goods (excluding food) for immediate consumption, and provide a variety of services on streets and in other public places such as stations. Most occupations in this sub-major group require skills at the first ISCO skill level.
Tasks performed by workers in this sub-major group usually include: buying or making various items for sale; loading and unloading items for sale and transporting them; obtaining the materials necessary to perform services; approaching people on the street to offer goods or services; cleaning and polishing shoes; cleaning and polishing car windows; running errands; assisting car drivers to find a parking place and ensuring that the car is not damaged during the driver’s absence; handing out leaflets and free newspapers; receiving immediate payment.
Occupations in this sub-major group are classified into the following minor groups:
951 Street and Related Services Workers
952 Street Vendors (excluding Food)"""@en ;
         rdfs:label "Street and related sales and service workers"@en ;
         skos:broaderTransitive ESCO:C9 .


###  http://data.europa.eu/esco/isco/C96
ESCO:C96 rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:Occupation ;
         rdfs:comment """Refuse workers and other elementary workers collect, process and recycle garbage from buildings, yards, streets and other public places. They keep streets and other public places clean and tidy, deliver and carry messages and packages and perform odd jobs for private households or establishments. Most occupations in this sub-major group require skills at the first ISCO skill level.
Tasks performed by workers in this sub-major group usually include: collecting, loading and unloading garbage; sweeping streets, parks and other public places; chopping firewood; collecting and carrying firewood, water, packages, luggage and messages; beating dust out of carpets and performing other odd-job tasks.
Occupations in this sub-major group are classified into the following minor groups:
961 Refuse Workers
962 Other Elementary Workers"""@en ;
         rdfs:label "Refuse workers and other elementary workers"@en ;
         skos:broaderTransitive ESCO:C9 .


###  http://purl.bioontology.org/ontology/ATC/A
ATC:A rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653992" ;
      rdfs:label "Alimentary Tract and Metabolism"@en .


###  http://purl.bioontology.org/ontology/ATC/A01
ATC:A01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653755" ;
        rdfs:label "Stomatological Preparations"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A02
ATC:A02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653499" ;
        rdfs:label "Drugs for Acid Related Disorders"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A02AD02
ATC:A02AD02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0065512" ;
            rdfs:label "Malgradate"@en ;
            skos:broaderTransitive ATC:A02 .


###  http://purl.bioontology.org/ontology/ATC/A02BC01
ATC:A02BC01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0028978 ;
            rdfs:label "Omeprazole"@en ;
            skos:broaderTransitive ATC:A02 .


###  http://purl.bioontology.org/ontology/ATC/A02BC02
ATC:A02BC02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0081876" ;
            rdfs:label "Pantoprazole"@en ;
            skos:broaderTransitive ATC:A02 .


###  http://purl.bioontology.org/ontology/ATC/A02BC05
ATC:A02BC05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0937846" ;
            rdfs:label "Esomeprazole"@en ;
            skos:broaderTransitive ATC:A02 .


###  http://purl.bioontology.org/ontology/ATC/A02BX06
ATC:A02BX06 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0033321" ;
            rdfs:label "Proglumide"@en ;
            skos:broaderTransitive ATC:A02 .


###  http://purl.bioontology.org/ontology/ATC/A03
ATC:A03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653766" ;
        rdfs:label "Drugs for Functional Gastrointestinal Disorders"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A03FA03
ATC:A03FA03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0013015" ;
            rdfs:label "Domperidone"@en ;
            skos:broaderTransitive ATC:A03 .


###  http://purl.bioontology.org/ontology/ATC/A04
ATC:A04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653765" ;
        rdfs:label "Antiemetics and Antinauseants"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A05
ATC:A05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3654041" ;
        rdfs:label "Bile and Liver Therapy Drugs"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A05A
ATC:A05A rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:PharmacologicSubstance ;
         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3654040" ;
         rdfs:label "Bile Therapy"@en ;
         skos:broaderTransitive ATC:A05 .


###  http://purl.bioontology.org/ontology/ATC/A05AA02
ATC:A05AA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042105" ;
            rdfs:label "Ursodeoxycholic Acid"@en ;
            skos:broaderTransitive ATC:A05A .


###  http://purl.bioontology.org/ontology/ATC/A05B
ATC:A05B rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:PharmacologicSubstance ;
         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653559" ;
         rdfs:label "Liver Therapy, Lipotropics"@en ;
         skos:broaderTransitive ATC:A05 .


###  http://purl.bioontology.org/ontology/ATC/A05C
ATC:A05C rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:PharmacologicSubstance ;
         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653658" ;
         rdfs:label "Drugs for Bile Therapy and Lipotropics in Combination"@en ;
         skos:broaderTransitive ATC:A05 .


###  http://purl.bioontology.org/ontology/ATC/A06
ATC:A06 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653756" ;
        rdfs:label "Drugs for Constipation"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A06AD11
ATC:A06AD11 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0022957" ;
            rdfs:label "Lactulose"@en ;
            skos:broaderTransitive ATC:A06 .


###  http://purl.bioontology.org/ontology/ATC/A07
ATC:A07 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653721" ;
        rdfs:label "Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agents"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A07EC01
ATC:A07EC01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0036078" ;
            rdfs:label "Sulfasalazine"@en .


###  http://purl.bioontology.org/ontology/ATC/A07EC02
ATC:A07EC02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0127615" ;
            rdfs:label "Mesalazine"@en ;
            skos:broaderTransitive ATC:A07 .


###  http://purl.bioontology.org/ontology/ATC/A08
ATC:A08 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653760" ;
        rdfs:label "Antiobesity Preparations, excl. Diet Products"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A09
ATC:A09 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653759" ;
        rdfs:label "Digestives, incl. Enzymes"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A10
ATC:A10 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653344" ;
        rdfs:label "Drugs Used in Diabetes"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A10A
ATC:A10A rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:PharmacologicSubstance ;
         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653579" ;
         rdfs:label "Insulins and Analogues"@en ;
         skos:broaderTransitive ATC:A10 .


###  http://purl.bioontology.org/ontology/ATC/A10AB04
ATC:A10AB04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0293359" ;
            rdfs:label "Insulin Lispro"@en ;
            skos:broaderTransitive ATC:A10A .


###  http://purl.bioontology.org/ontology/ATC/A10AE04
ATC:A10AE04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0907402" ;
            rdfs:label "Insulin Glargine"@en ;
            skos:broaderTransitive ATC:A10A .


###  http://purl.bioontology.org/ontology/ATC/A10BA02
ATC:A10BA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0025598" ;
            rdfs:label "Metformin"@en ;
            skos:broaderTransitive ATC:A10 .


###  http://purl.bioontology.org/ontology/ATC/A10BB09
ATC:A10BB09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0017631" ;
            rdfs:label "Gliclazide"@en ;
            skos:broaderTransitive ATC:A10 .


###  http://purl.bioontology.org/ontology/ATC/A10BB12
ATC:A10BB12 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0061323" ;
            rdfs:label "Glimepiride"@en ;
            skos:broaderTransitive ATC:A10 .


###  http://purl.bioontology.org/ontology/ATC/A10BH01
ATC:A10BH01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1565750" ;
            rdfs:label "Sitagliptin"@en ;
            skos:broaderTransitive ATC:A10 .


###  http://purl.bioontology.org/ontology/ATC/A10BJ06
ATC:A10BJ06 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C3885068 ;
            rdfs:label "Semaglutide"@en ;
            skos:broaderTransitive ATC:A10 .


###  http://purl.bioontology.org/ontology/ATC/A10BX02
ATC:A10BX02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0246689 ;
            rdfs:label "Repaglinide"@en ;
            skos:broaderTransitive ATC:A10 .


###  http://purl.bioontology.org/ontology/ATC/A11
ATC:A11 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042890" ;
        rdfs:label "Vitamins"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A11CC05
ATC:A11CC05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0008318" ;
            rdfs:label "Colecalciferol"@en ;
            skos:broaderTransitive ATC:A11 .


###  http://purl.bioontology.org/ontology/ATC/A11CC06
ATC:A11CC06 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006657" ;
            rdfs:label "Calcifediol"@en ;
            skos:broaderTransitive ATC:A11 .


###  http://purl.bioontology.org/ontology/ATC/A11HA05
ATC:A11HA05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005575" ;
            rdfs:label "Biotin"@en ;
            skos:broaderTransitive ATC:A11 .


###  http://purl.bioontology.org/ontology/ATC/A12
ATC:A12 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0556112" ;
        rdfs:label "Mineral Supplements"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A12AX
ATC:A12AX rdf:type owl:NamedIndividual ,
                   skos:Concept ,
                   bto:PharmacologicSubstance ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653309" ;
          rdfs:label "Calcium, Combinations with Vitamin D and/or Other Drugs"@en ;
          skos:broaderTransitive ATC:A12 .


###  http://purl.bioontology.org/ontology/ATC/A13
ATC:A13 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3543842" ;
        rdfs:label "Tonics"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A14
ATC:A14 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653709" ;
        rdfs:label "Anabolic Agents for Systemic Use"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A15
ATC:A15 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0376447" ;
        rdfs:label "Appetite Stimulants"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A16
ATC:A16 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3542964" ;
        rdfs:label "Other Alimentary Tract and Metabolism"@en ;
        skos:broaderTransitive ATC:A .


###  http://purl.bioontology.org/ontology/ATC/A16AA02
ATC:A16AA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0036002" ;
            rdfs:label "Ademetionine"@en ;
            skos:broaderTransitive ATC:A16 .


###  http://purl.bioontology.org/ontology/ATC/B
ATC:B rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3654015" ;
      rdfs:label "Blood and Blood Forming Organs"@en .


###  http://purl.bioontology.org/ontology/ATC/B01
ATC:B01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1704311" ;
        rdfs:label "Antithrombotic Agents"@en ;
        skos:broaderTransitive ATC:B .


###  http://purl.bioontology.org/ontology/ATC/B01AA03
ATC:B01AA03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0043031" ;
            rdfs:label "Warfarin"@en ;
            skos:broaderTransitive ATC:B01 .


###  http://purl.bioontology.org/ontology/ATC/B01AC04
ATC:B01AC04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0070166" ;
            rdfs:label "Clopidogrel"@en ;
            skos:broaderTransitive ATC:B01 .


###  http://purl.bioontology.org/ontology/ATC/B01AC05
ATC:B01AC05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040207" ;
            rdfs:label "Ticlopidine"@en ;
            skos:broaderTransitive ATC:B01 .


###  http://purl.bioontology.org/ontology/ATC/B01AC22
ATC:B01AC22 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1620287" ;
            rdfs:label "Prasugrel"@en ;
            skos:broaderTransitive ATC:B01 .


###  http://purl.bioontology.org/ontology/ATC/B01AE07
ATC:B01AE07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1571583 ;
            rdfs:label "Dabigatran Etexilate"@en ;
            skos:broaderTransitive ATC:B01 .


###  http://purl.bioontology.org/ontology/ATC/B01AF01
ATC:B01AF01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1739768" ;
            rdfs:label "Rivaroxaban"@en ;
            skos:broaderTransitive ATC:B01 .


###  http://purl.bioontology.org/ontology/ATC/B01AF02
ATC:B01AF02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1831808 ;
            rdfs:label "Apixaban"@en ;
            skos:broaderTransitive ATC:B01 .


###  http://purl.bioontology.org/ontology/ATC/B02
ATC:B02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0085824" ;
        rdfs:label "Antihemorrhagics"@en ;
        skos:broaderTransitive ATC:B .


###  http://purl.bioontology.org/ontology/ATC/B03
ATC:B03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653788" ;
        rdfs:label "Antianemic Preparations"@en ;
        skos:broaderTransitive ATC:B .


###  http://purl.bioontology.org/ontology/ATC/B03BA01
ATC:B03BA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042845" ;
            rdfs:label "Cyanocobalamin"@en ;
            skos:broaderTransitive ATC:B03 .


###  http://purl.bioontology.org/ontology/ATC/B05
ATC:B05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653601" ;
        rdfs:label "Blood Substitutes and Perfusion Solutions"@en ;
        skos:broaderTransitive ATC:B .


###  http://purl.bioontology.org/ontology/ATC/B06
ATC:B06 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3540010" ;
        rdfs:label "Other Hematological Agents"@en ;
        skos:broaderTransitive ATC:B .


###  http://purl.bioontology.org/ontology/ATC/C
ATC:C rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3540036" ;
      rdfs:label "Cardiovascular System"@en .


###  http://purl.bioontology.org/ontology/ATC/C01
ATC:C01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3654025" ;
        rdfs:label "Cardiac Therapy"@en .


###  http://purl.bioontology.org/ontology/ATC/C01BD01
ATC:C01BD01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002598" ;
            rdfs:label "Amiodarone"@en ;
            skos:broaderTransitive ATC:C01 .


###  http://purl.bioontology.org/ontology/ATC/C02
ATC:C02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003364" ;
        rdfs:label "Antihypertensives"@en ;
        skos:broaderTransitive ATC:C .


###  http://purl.bioontology.org/ontology/ATC/C02KX02
ATC:C02KX02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1176329 ;
            rdfs:label "Ambrisentan"@en ;
            skos:broaderTransitive ATC:C02 .


###  http://purl.bioontology.org/ontology/ATC/C03
ATC:C03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0012798" ;
        rdfs:label "Diuretics"@en ;
        skos:broaderTransitive ATC:C .


###  http://purl.bioontology.org/ontology/ATC/C03AA03
ATC:C03AA03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0020261 ;
            rdfs:label "Hydrochlorothiazide"@en ;
            skos:broaderTransitive ATC:C03 .


###  http://purl.bioontology.org/ontology/ATC/C03CA01
ATC:C03CA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0016860" ;
            rdfs:label "Furosemide"@en ;
            skos:broaderTransitive ATC:C03 .


###  http://purl.bioontology.org/ontology/ATC/C04
ATC:C04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0724804" ;
        rdfs:label "Peripheral Vasodilators"@en ;
        skos:broaderTransitive ATC:C .


###  http://purl.bioontology.org/ontology/ATC/C04AE02
ATC:C04AE02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0028008" ;
            rdfs:label "Nicergoline"@en ;
            skos:broaderTransitive ATC:C04 .


###  http://purl.bioontology.org/ontology/ATC/C05
ATC:C05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0304533" ;
        rdfs:label "Vasoprotectives"@en ;
        skos:broaderTransitive ATC:C .


###  http://purl.bioontology.org/ontology/ATC/C07
ATC:C07 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001645" ;
        rdfs:label "Beta Blocking Agents"@en ;
        skos:broaderTransitive ATC:C .


###  http://purl.bioontology.org/ontology/ATC/C07AA05
ATC:C07AA05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0033497" ;
            rdfs:label "Propanolol"@en ;
            skos:broaderTransitive ATC:C07 .


###  http://purl.bioontology.org/ontology/ATC/C07AB03
ATC:C07AB03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004147" ;
            rdfs:label "Atenolol"@en ;
            skos:broaderTransitive ATC:C07 .


###  http://purl.bioontology.org/ontology/ATC/C07AB07
ATC:C07AB07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0053799" ;
            rdfs:label "Bisoprolol"@en ;
            skos:broaderTransitive ATC:C07 .


###  http://purl.bioontology.org/ontology/ATC/C07AB12
ATC:C07AB12 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0068475" ;
            rdfs:label "Nebivolol"@en ;
            skos:broaderTransitive ATC:C07 .


###  http://purl.bioontology.org/ontology/ATC/C07CB03
ATC:C07CB03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653013" ;
            rdfs:label "Atenolol and Other Diuretics"@en ;
            skos:broaderTransitive ATC:C07 .


###  http://purl.bioontology.org/ontology/ATC/C08
ATC:C08 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        rdfs:label "Calcium Channel Blockers"@en ;
        skos:broaderTransitive ATC:C .


###  http://purl.bioontology.org/ontology/ATC/C08CA01
ATC:C08CA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0051696" ;
            rdfs:label "Amlodipine"@en ;
            skos:broaderTransitive ATC:C08 .


###  http://purl.bioontology.org/ontology/ATC/C08CA12
ATC:C08CA12 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0078703" ;
            rdfs:label "Barnidipine"@en ;
            skos:broaderTransitive ATC:C08 .


###  http://purl.bioontology.org/ontology/ATC/C08CA13
ATC:C08CA13 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0526399" ;
            rdfs:label "Lercanidipine"@en ;
            skos:broaderTransitive ATC:C08 .


###  http://purl.bioontology.org/ontology/ATC/C08DA01
ATC:C08DA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042523" ;
            rdfs:label "Verapamil"@en ;
            skos:broaderTransitive ATC:C08 .


###  http://purl.bioontology.org/ontology/ATC/C09
ATC:C09 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653735" ;
        rdfs:label "Agents Acting on the Renin-Angiotensin System"@en ;
        skos:broaderTransitive ATC:C .


###  http://purl.bioontology.org/ontology/ATC/C09AA
ATC:C09AA rdf:type owl:NamedIndividual ,
                   skos:Concept ,
                   bto:PharmacologicSubstance ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653768" ;
          rdfs:label "ACE Inhibitors, Plain"@en ;
          skos:broaderTransitive ATC:C09 .


###  http://purl.bioontology.org/ontology/ATC/C09AA02
ATC:C09AA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0014025" ;
            rdfs:label "Enalapril"@en ;
            skos:broaderTransitive ATC:C09AA .


###  http://purl.bioontology.org/ontology/ATC/C09AA05
ATC:C09AA05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0072973" ;
            rdfs:label "Ramipril"@en ;
            skos:broaderTransitive ATC:C09AA .


###  http://purl.bioontology.org/ontology/ATC/C09BB04
ATC:C09BB04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2931929" ;
            rdfs:label "Perindopril and Amlodipine"@en ;
            skos:broaderTransitive ATC:C09AA .


###  http://purl.bioontology.org/ontology/ATC/C09CA01
ATC:C09CA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0126174" ;
            rdfs:label "Losartan"@en ;
            skos:broaderTransitive ATC:C09AA .


###  http://purl.bioontology.org/ontology/ATC/C09CA03
ATC:C09CA03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0216784 ;
            rdfs:label "Valsartan"@en ;
            skos:broaderTransitive ATC:C09 .


###  http://purl.bioontology.org/ontology/ATC/C09CA07
ATC:C09CA07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0248719" ;
            rdfs:label "Telmisartan"@en ;
            skos:broaderTransitive ATC:C09AA .


###  http://purl.bioontology.org/ontology/ATC/C09CA08
ATC:C09CA08 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0386393" ;
            rdfs:label "Olmesartan Medoxomil"@en ;
            skos:broaderTransitive ATC:C09AA .


###  http://purl.bioontology.org/ontology/ATC/C09DA06
ATC:C09DA06 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C3653044 ;
            rdfs:label "Candesartan and Diuretics"@en ;
            skos:broaderTransitive ATC:C09 .


###  http://purl.bioontology.org/ontology/ATC/C09DB02
ATC:C09DB02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C3652731 ;
            rdfs:label "Olmesartan Medoxomil and Amlodipine"@en ;
            skos:broaderTransitive ATC:C09 .


###  http://purl.bioontology.org/ontology/ATC/C10
ATC:C10 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653535" ;
        rdfs:label "Lipid Modifying Agents"@en ;
        skos:broaderTransitive ATC:C .


###  http://purl.bioontology.org/ontology/ATC/C10AA
ATC:C10AA rdf:type owl:NamedIndividual ,
                   skos:Concept ,
                   bto:PharmacologicSubstance ;
          dcterms:conformsTo UMLS:C3539119 ;
          rdfs:label "HMG CoA Reductase Inhibitors"@en ;
          skos:broaderTransitive ATC:C10 .


###  http://purl.bioontology.org/ontology/ATC/C10AA01
ATC:C10AA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0074554" ;
            rdfs:label "Simvastatin"@en ;
            skos:broaderTransitive ATC:C10AA .


###  http://purl.bioontology.org/ontology/ATC/C10AA05
ATC:C10AA05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0286651" ;
            rdfs:label "Atrovastatin"@en ;
            skos:broaderTransitive ATC:C10AA .


###  http://purl.bioontology.org/ontology/ATC/C10AA07
ATC:C10AA07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0965129 ;
            rdfs:label "Rosuvastatin"@en ;
            skos:broaderTransitive ATC:C10 .


###  http://purl.bioontology.org/ontology/ATC/C10AX09
ATC:C10AX09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1142985 ;
            rdfs:label "Ezetimibe"@en ;
            skos:broaderTransitive ATC:C10 .


###  http://purl.bioontology.org/ontology/ATC/D
ATC:D rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011625" ;
      rdfs:label "Dermatologicals"@en .


###  http://purl.bioontology.org/ontology/ATC/D01
ATC:D01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653281" ;
        rdfs:label "Antifungals for Dermatological Use"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D02
ATC:D02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653752" ;
        rdfs:label "Emollients and Protectives"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D03
ATC:D03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653566" ;
        rdfs:label "Preparations for Treatment of Wounds and Ulcers"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D04
ATC:D04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653761" ;
        rdfs:label "Antipruritics, incl. Antihistamines, Anesthetics, etc."@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D05
ATC:D05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1874314" ;
        rdfs:label "Antipsoriatics"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D06
ATC:D06 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653726" ;
        rdfs:label "Antibiotics and Chemotherapeutics for Dermatological Use"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D07
ATC:D07 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        rdfs:label "Corticosteroids, Dermatological Preparations"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D07AA02
ATC:D07AA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020268" ;
            rdfs:label "Hydrocortisone"@en ;
            skos:broaderTransitive ATC:D07 .


###  http://purl.bioontology.org/ontology/ATC/D08
ATC:D08 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653284" ;
        rdfs:label "Antispetic and Disinfectants"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D09
ATC:D09 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0471863" ;
        rdfs:label "Medicated Dressings"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D10
ATC:D10 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0358061" ;
        rdfs:label "Anti-Acne Preparations"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/D11
ATC:D11 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653942" ;
        rdfs:label "Other Dermatological Preparations"@en ;
        skos:broaderTransitive ATC:D .


###  http://purl.bioontology.org/ontology/ATC/G
ATC:G rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653431" ;
      rdfs:label "Genito Urinary System and Sex Hormones"@en .


###  http://purl.bioontology.org/ontology/ATC/G01
ATC:G01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653587" ;
        rdfs:label "Gynecological Antiinfectives and Antiseptics"@en ;
        skos:broaderTransitive ATC:G .


###  http://purl.bioontology.org/ontology/ATC/G02
ATC:G02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653939" ;
        rdfs:label "Other Gynecologicals"@en ;
        skos:broaderTransitive ATC:G .


###  http://purl.bioontology.org/ontology/ATC/G03
ATC:G03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653561" ;
        rdfs:label "Sex Hormones and Modulators of the Genital System"@en ;
        skos:broaderTransitive ATC:G .


###  http://purl.bioontology.org/ontology/ATC/G03AA09
ATC:G03AA09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1112096" ;
            rdfs:label "Desogestrel and Ethinylestradiol"@en ;
            skos:broaderTransitive ATC:G03 .


###  http://purl.bioontology.org/ontology/ATC/G03AA12
ATC:G03AA12 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2604206" ;
            rdfs:label "Drospirenone and Ethinylestradiol"@en ;
            skos:broaderTransitive ATC:G03 .


###  http://purl.bioontology.org/ontology/ATC/G03AB
ATC:G03AB rdf:type owl:NamedIndividual ,
                   skos:Concept ,
                   bto:PharmacologicSubstance ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3540748" ;
          rdfs:label "Progestogens and Estrogens Systemic Contraceptives, Sequential Preparations"@en ;
          skos:broaderTransitive ATC:G03 .


###  http://purl.bioontology.org/ontology/ATC/G03AB08
ATC:G03AB08 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C2936902 ;
            rdfs:label "Dienogest and Estradiol"@en ;
            skos:broaderTransitive ATC:G03 .


###  http://purl.bioontology.org/ontology/ATC/G03AC08
ATC:G03AC08 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0047683 ;
            rdfs:label "Etonogestrel"@en ;
            skos:broaderTransitive ATC:G03 .


###  http://purl.bioontology.org/ontology/ATC/G03AC09
ATC:G03AC09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0057558 ;
            rdfs:label "Desogestrel"@en ;
            skos:broaderTransitive ATC:G03 .


###  http://purl.bioontology.org/ontology/ATC/G03CX01
ATC:G03CX01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0076660 ;
            rdfs:label "Tibolone"@en ;
            skos:broaderTransitive ATC:G03 .


###  http://purl.bioontology.org/ontology/ATC/G04
ATC:G04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653764" ;
        rdfs:label "Urologicals"@en ;
        skos:broaderTransitive ATC:G .


###  http://purl.bioontology.org/ontology/ATC/G04BD04
ATC:G04BD04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0069805" ;
            rdfs:label "Oxybutynin"@en ;
            skos:broaderTransitive ATC:G04 .


###  http://purl.bioontology.org/ontology/ATC/G04BD07
ATC:G04BD07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0388753" ;
            rdfs:label "Tolterodine"@en ;
            skos:broaderTransitive ATC:G04 .


###  http://purl.bioontology.org/ontology/ATC/G04BD09
ATC:G04BD09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0772089" ;
            rdfs:label "Trospium"@en ;
            skos:broaderTransitive ATC:G04 .


###  http://purl.bioontology.org/ontology/ATC/G04BE03
ATC:G04BE03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0529793" ;
            rdfs:label "Sildenafil"@en ;
            skos:broaderTransitive ATC:G04 .


###  http://purl.bioontology.org/ontology/ATC/G04BE08
ATC:G04BE08 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1176316 ;
            rdfs:label "Tadalafil"@en ;
            skos:broaderTransitive ATC:G04 .


###  http://purl.bioontology.org/ontology/ATC/G04CA01
ATC:G04CA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0051150 ;
            rdfs:label "Alfuzosin"@en ;
            skos:broaderTransitive ATC:G04 .


###  http://purl.bioontology.org/ontology/ATC/G04CA02
ATC:G04CA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0257343" ;
            rdfs:label "Tamsulosin"@en ;
            skos:broaderTransitive ATC:G04 .


###  http://purl.bioontology.org/ontology/ATC/G04CB02
ATC:G04CB02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0754659 ;
            rdfs:label "Dustasteride"@en ;
            skos:broaderTransitive ATC:G04 .


###  http://purl.bioontology.org/ontology/ATC/H
ATC:H rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653821" ;
      rdfs:label "Systemic Hormonal Preparations, excl. Sex Hormones and Insulins"@en .


###  http://purl.bioontology.org/ontology/ATC/H01
ATC:H01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653567" ;
        rdfs:label "Pituitary and Hypothalamic Hormones and Analogues"@en ;
        skos:broaderTransitive ATC:H .


###  http://purl.bioontology.org/ontology/ATC/H01AA01
ATC:H01AA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001655" ;
            rdfs:label "Corticotropin"@en ;
            skos:broaderTransitive ATC:H01 .


###  http://purl.bioontology.org/ontology/ATC/H01AA02
ATC:H01AA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0010192" ;
            rdfs:label "Tetracosactide"@en ;
            skos:broaderTransitive ATC:H01 .


###  http://purl.bioontology.org/ontology/ATC/H02
ATC:H02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653708" ;
        rdfs:label "Corticosteroids for Systemic Use"@en ;
        skos:broaderTransitive ATC:H .


###  http://purl.bioontology.org/ontology/ATC/H02AB
ATC:H02AB rdf:type owl:NamedIndividual ,
                   skos:Concept ,
                   bto:PharmacologicSubstance ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3540777" ;
          rdfs:label "Glucocorticoids, Systemic"@en ;
          skos:broaderTransitive ATC:H02 .


###  http://purl.bioontology.org/ontology/ATC/H02AB01
ATC:H02AB01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005308" ;
            rdfs:label "Betamethasone"@en ;
            skos:broaderTransitive ATC:H02AB .


###  http://purl.bioontology.org/ontology/ATC/H02AB02
ATC:H02AB02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011777" ;
            rdfs:label "Dexamethasone"@en ;
            skos:broaderTransitive ATC:H02AB .


###  http://purl.bioontology.org/ontology/ATC/H02AB04
ATC:H02AB04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0025815" ;
            rdfs:label "Methylprednisolone"@en ;
            skos:broaderTransitive ATC:H02AB .


###  http://purl.bioontology.org/ontology/ATC/H02AB06
ATC:H02AB06 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032950" ;
            rdfs:label "Prednisolone"@en ;
            skos:broaderTransitive ATC:H02AB .


###  http://purl.bioontology.org/ontology/ATC/H02AB07
ATC:H02AB07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032952" ;
            rdfs:label "Prednisone"@en ;
            skos:broaderTransitive ATC:H02AB .


###  http://purl.bioontology.org/ontology/ATC/H02AB09
ATC:H02AB09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020268" ;
            rdfs:label "Hydrocortisone"@en ;
            skos:broaderTransitive ATC:H02AB .


###  http://purl.bioontology.org/ontology/ATC/H02AB13
ATC:H02AB13 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0057258" ;
            rdfs:label "Deflazacort"@en ;
            skos:broaderTransitive ATC:H02AB .


###  http://purl.bioontology.org/ontology/ATC/H03
ATC:H03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3540775" ;
        rdfs:label "Thyroid Therapy"@en ;
        skos:broaderTransitive ATC:H .


###  http://purl.bioontology.org/ontology/ATC/H03AA01
ATC:H03AA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0079691" ;
            rdfs:label "Levothyroxine Sodium"@en ;
            skos:broaderTransitive ATC:H03 .


###  http://purl.bioontology.org/ontology/ATC/H03BB02
ATC:H03BB02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0025644" ;
            rdfs:label "Thiamazole"@en ;
            skos:broaderTransitive ATC:H03 .


###  http://purl.bioontology.org/ontology/ATC/H04
ATC:H04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0030292" ;
        rdfs:label "Pancreatic Hormones"@en ;
        skos:broaderTransitive ATC:H .


###  http://purl.bioontology.org/ontology/ATC/H05
ATC:H05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653518" ;
        rdfs:label "Calcium Homeostasis"@en ;
        skos:broaderTransitive ATC:H .


###  http://purl.bioontology.org/ontology/ATC/J
ATC:J rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653775" ;
      rdfs:label "Antiinfectives for Systemic Use"@en .


###  http://purl.bioontology.org/ontology/ATC/J01
ATC:J01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653727" ;
        rdfs:label "Antibacterials for Systemic Use"@en ;
        skos:broaderTransitive ATC:J .


###  http://purl.bioontology.org/ontology/ATC/J01CR02
ATC:J01CR02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653015" ;
            rdfs:label "Amoxicillin and Beta-Lactamase Inhibitor"@en ;
            skos:broaderTransitive ATC:J01 .


###  http://purl.bioontology.org/ontology/ATC/J01DD04
ATC:J01DD04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007561" ;
            rdfs:label "Ceftriaxone"@en ;
            skos:broaderTransitive ATC:J01 .


###  http://purl.bioontology.org/ontology/ATC/J02
ATC:J02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653762" ;
        rdfs:label "Antimycotics for Systemic Use"@en ;
        skos:broaderTransitive ATC:J .


###  http://purl.bioontology.org/ontology/ATC/J04
ATC:J04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0360390" ;
        rdfs:label "Antimycobacterials"@en ;
        skos:broaderTransitive ATC:J .


###  http://purl.bioontology.org/ontology/ATC/J04AB02
ATC:J04AB02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0035608" ;
            rdfs:label "Rifampicin"@en ;
            skos:broaderTransitive ATC:J04 .


###  http://purl.bioontology.org/ontology/ATC/J05
ATC:J05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653777" ;
        rdfs:label "Antivirals for Systemic Use"@en ;
        skos:broaderTransitive ATC:J .


###  http://purl.bioontology.org/ontology/ATC/J05AB01
ATC:J05AB01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001367" ;
            rdfs:label "Aciclovir"@en ;
            skos:broaderTransitive ATC:J05 .


###  http://purl.bioontology.org/ontology/ATC/J05AB11
ATC:J05AB11 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0249458" ;
            rdfs:label "Valaciclovir"@en ;
            skos:broaderTransitive ATC:J05 .


###  http://purl.bioontology.org/ontology/ATC/J06
ATC:J06 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653581" ;
        rdfs:label "Immune Sera and Immunoglobulins"@en ;
        skos:broaderTransitive ATC:J .


###  http://purl.bioontology.org/ontology/ATC/J06BA02
ATC:J06BA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3652960" ;
            rdfs:label "Immunoglobulins, Normal Human, for Intravascular Adm."@en ;
            skos:broaderTransitive ATC:J06 .


###  http://purl.bioontology.org/ontology/ATC/J06BB02
ATC:J06BB02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C4048265" ;
            rdfs:label "Tetanus Immunoglobulin"@en ;
            skos:broaderTransitive ATC:J06 .


###  http://purl.bioontology.org/ontology/ATC/J07
ATC:J07 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042210" ;
        rdfs:label "Vaccines"@en ;
        skos:broaderTransitive ATC:J .


###  http://purl.bioontology.org/ontology/ATC/J07AF
ATC:J07AF rdf:type owl:NamedIndividual ,
                   skos:Concept ,
                   bto:PharmacologicSubstance ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0012551" ;
          rdfs:label "Diphtheria Vaccines"@en ;
          skos:broaderTransitive ATC:J07 .


###  http://purl.bioontology.org/ontology/ATC/J07BC01
ATC:J07BC01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3652493" ;
            rdfs:label "Hepatitis B, Purified Antigen"@en ;
            skos:broaderTransitive ATC:J07 .


###  http://purl.bioontology.org/ontology/ATC/J07BF03
ATC:J07BF03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3652521" ;
            rdfs:label "Poliomyelitis, Trivalent, Inactivated, Whole Virus"@en ;
            skos:broaderTransitive ATC:J07 .


###  http://purl.bioontology.org/ontology/ATC/J07BX
ATC:J07BX rdf:type owl:NamedIndividual ,
                   skos:Concept ,
                   bto:PharmacologicSubstance ;
          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653947" ;
          rdfs:label "Other Vaccines"@en ;
          skos:broaderTransitive ATC:J07 .


###  http://purl.bioontology.org/ontology/ATC/L
ATC:L rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653621" ;
      rdfs:label "Antineoplastic and Immunomodulating Agents"@en .


###  http://purl.bioontology.org/ontology/ATC/L01
ATC:L01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003392" ;
        rdfs:label "Antineoplastic Agents"@en ;
        skos:broaderTransitive ATC:L .


###  http://purl.bioontology.org/ontology/ATC/L01AA01
ATC:L01AA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0010583" ;
            rdfs:label "Cyclophosphamide"@en ;
            skos:broaderTransitive ATC:L01 .


###  http://purl.bioontology.org/ontology/ATC/L01BA01
ATC:L01BA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0025677" ;
            rdfs:label "Methotrexate"@en ;
            skos:broaderTransitive ATC:L01 .


###  http://purl.bioontology.org/ontology/ATC/L01BB04
ATC:L01BB04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0092801" ;
            rdfs:label "Cladribine"@en ;
            skos:broaderTransitive ATC:L01 .


###  http://purl.bioontology.org/ontology/ATC/L01DB07
ATC:L01DB07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0026259" ;
            rdfs:label "Mitoxantrone"@en ;
            skos:broaderTransitive ATC:L01 .


###  http://purl.bioontology.org/ontology/ATC/L01ED03
ATC:L01ED03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3853921" ;
            rdfs:label "Alectinib"@en ;
            skos:broaderTransitive ATC:L01 .


###  http://purl.bioontology.org/ontology/ATC/L01FA02
ATC:L01FA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1832027 ;
            rdfs:label "Ofatumumab"@en ;
            skos:broaderTransitive ATC:L01 .


###  http://purl.bioontology.org/ontology/ATC/L01XC02
ATC:L01XC02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0393022" ;
            rdfs:label "Rituximab"@en ;
            skos:broaderTransitive ATC:L01 .


###  http://purl.bioontology.org/ontology/ATC/L01XC03
ATC:L01XC03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0728747" ;
            rdfs:label "Trastuzumab"@en ;
            skos:broaderTransitive ATC:L01 .


###  http://purl.bioontology.org/ontology/ATC/L02
ATC:L02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3540795" ;
        rdfs:label "Endocrine Therapy"@en ;
        skos:broaderTransitive ATC:L .


###  http://purl.bioontology.org/ontology/ATC/L02BA01
ATC:L02BA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0039286" ;
            rdfs:label "Tamoxifen"@en ;
            skos:broaderTransitive ATC:L02 .


###  http://purl.bioontology.org/ontology/ATC/L03
ATC:L03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001551" ;
        rdfs:label "Immunostimulants"@en ;
        skos:broaderTransitive ATC:L .


###  http://purl.bioontology.org/ontology/ATC/L03AB02
ATC:L03AB02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015980" ;
            rdfs:label "Interferon Beta Natural"@en ;
            skos:broaderTransitive ATC:L03 .


###  http://purl.bioontology.org/ontology/ATC/L03AB07
ATC:L03AB07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0254119" ;
            rdfs:label "Interferon Beta-1a"@en ;
            skos:broaderTransitive ATC:L03 .


###  http://purl.bioontology.org/ontology/ATC/L03AB08
ATC:L03AB08 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0244713" ;
            rdfs:label "Interferon Beta-1b"@en ;
            skos:broaderTransitive ATC:L03 .


###  http://purl.bioontology.org/ontology/ATC/L03AB10
ATC:L03AB10 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0796545" ;
            rdfs:label "Peginterferon Alfa-2b"@en ;
            skos:broaderTransitive ATC:L03 .


###  http://purl.bioontology.org/ontology/ATC/L03AB13
ATC:L03AB13 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3848580" ;
            rdfs:label "Peginterferon Beta-1a"@en ;
            skos:broaderTransitive ATC:L03 .


###  http://purl.bioontology.org/ontology/ATC/L03AX03
ATC:L03AX03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004886" ;
            rdfs:label "BCG Vaccine"@en ;
            skos:broaderTransitive ATC:L03 .


###  http://purl.bioontology.org/ontology/ATC/L03AX13
ATC:L03AX13 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0289884" ;
            rdfs:label "Glatiramer Acetate"@en ;
            skos:broaderTransitive ATC:L03 .


###  http://purl.bioontology.org/ontology/ATC/L04
ATC:L04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0021081" ;
        rdfs:label "Immunosuppressants"@en ;
        skos:broaderTransitive ATC:L .


###  http://purl.bioontology.org/ontology/ATC/L04AA23
ATC:L04AA23 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1172734" ;
            rdfs:label "Natalizumab"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AA27
ATC:L04AA27 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1699926" ;
            rdfs:label "Fingolimod"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AA31
ATC:L04AA31 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1718383" ;
            rdfs:label "Teriflunomide"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AA34
ATC:L04AA34 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0383429" ;
            rdfs:label "Alemtuzumab"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AA36
ATC:L04AA36 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1882138" ;
            rdfs:label "Ocrelizumab"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AA38
ATC:L04AA38 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C4278675 ;
            rdfs:label "Ozanimod"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AA40
ATC:L04AA40 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0092801" ;
            rdfs:label "Cladribine"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AA42
ATC:L04AA42 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3657824" ;
            rdfs:label "Siponimod"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AC01
ATC:L04AC01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0663182" ;
            rdfs:label "Daclizumab"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AC05
ATC:L04AC05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1608841" ;
            rdfs:label "Ustekinumab"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AC07
ATC:L04AC07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1609165" ;
            rdfs:label "Tocilizumab"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AC10
ATC:L04AC10 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3179547" ;
            rdfs:label "Secukinumab"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AX01
ATC:L04AX01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004482" ;
            rdfs:label "Azathioprine"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AX03
ATC:L04AX03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0025677" ;
            rdfs:label "Methotrexate"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/L04AX07
ATC:L04AX07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0058218" ;
            rdfs:label "Dimethyl Fumarate"@en ;
            skos:broaderTransitive ATC:L04 .


###  http://purl.bioontology.org/ontology/ATC/M
ATC:M rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653821" ;
      rdfs:label "Musculo-Skeletal System"@en .


###  http://purl.bioontology.org/ontology/ATC/M01
ATC:M01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653623" ;
        rdfs:label "Antiinflammatory and Antirheumatic Products"@en ;
        skos:broaderTransitive ATC:M .


###  http://purl.bioontology.org/ontology/ATC/M01A
ATC:M01A rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:PharmacologicSubstance ;
         dcterms:conformsTo UMLS:C3653622 ;
         rdfs:label "Antiinflammatory and Antirheumatic Products, Non-Steroids"@en ;
         skos:broaderTransitive ATC:M01 .


###  http://purl.bioontology.org/ontology/ATC/M01AB01
ATC:M01AB01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0021246" ;
            rdfs:label "Indometacin"@en ;
            skos:broaderTransitive ATC:M01 .


###  http://purl.bioontology.org/ontology/ATC/M01AB15
ATC:M01AB15 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0073631" ;
            rdfs:label "Ketorolac"@en ;
            skos:broaderTransitive ATC:M01 .


###  http://purl.bioontology.org/ontology/ATC/M01AE01
ATC:M01AE01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020740" ;
            rdfs:label "Ibuprofen"@en ;
            skos:broaderTransitive ATC:M01 .


###  http://purl.bioontology.org/ontology/ATC/M01AH05
ATC:M01AH05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0972314" ;
            rdfs:label "Etoricoxib"@en ;
            skos:broaderTransitive ATC:M01 .


###  http://purl.bioontology.org/ontology/ATC/M02
ATC:M02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653753" ;
        rdfs:label "Topical Products for Joint and Muscular Pain"@en ;
        skos:broaderTransitive ATC:M .


###  http://purl.bioontology.org/ontology/ATC/M03
ATC:M03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0358430" ;
        rdfs:label "Muscle Relaxants"@en ;
        skos:broaderTransitive ATC:M .


###  http://purl.bioontology.org/ontology/ATC/M03AX01
ATC:M03AX01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006055" ;
            rdfs:label "Botulinum Toxin"@en ;
            skos:broaderTransitive ATC:M03 .


###  http://purl.bioontology.org/ontology/ATC/M03BX01
ATC:M03BX01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004609" ;
            rdfs:label "Baclofen"@en ;
            skos:broaderTransitive ATC:M03 .


###  http://purl.bioontology.org/ontology/ATC/M03BX02
ATC:M03BX02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0146011" ;
            rdfs:label "Tizanidine"@en ;
            skos:broaderTransitive ATC:M03 .


###  http://purl.bioontology.org/ontology/ATC/M03CA01
ATC:M03CA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0010976" ;
            rdfs:label "Dantrolene"@en ;
            skos:broaderTransitive ATC:M03 .


###  http://purl.bioontology.org/ontology/ATC/M04
ATC:M04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0018100" ;
        rdfs:label "Antigout Preparations"@en ;
        skos:broaderTransitive ATC:M .


###  http://purl.bioontology.org/ontology/ATC/M05
ATC:M05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653497" ;
        rdfs:label "Drugs for Treatment of Bone Diseases"@en ;
        skos:broaderTransitive ATC:M .


###  http://purl.bioontology.org/ontology/ATC/M05BX04
ATC:M05BX04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1690432" ;
            rdfs:label "Denosumab"@en ;
            skos:broaderTransitive ATC:M05 .


###  http://purl.bioontology.org/ontology/ATC/M09
ATC:M09 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653872" ;
        rdfs:label "Other Drugs for Disorders of the Musculo-Skeletal System"@en ;
        skos:broaderTransitive ATC:M .


###  http://purl.bioontology.org/ontology/ATC/N
ATC:N rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3542961" ;
      rdfs:label "Nervous System"@en .


###  http://purl.bioontology.org/ontology/ATC/N01
ATC:N01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002932" ;
        rdfs:label "Anesthetics"@en ;
        skos:broaderTransitive ATC:N .


###  http://purl.bioontology.org/ontology/ATC/N02
ATC:N02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002771" ;
        rdfs:label "Analgesics"@en ;
        skos:broaderTransitive ATC:N .


###  http://purl.bioontology.org/ontology/ATC/N02AA59
ATC:N02AA59 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653191" ;
            rdfs:label "Codeine, Combinations excl. Psycholeptics"@en ;
            skos:broaderTransitive ATC:N02 .


###  http://purl.bioontology.org/ontology/ATC/N02BA01
ATC:N02BA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0004057 ;
            rdfs:label "Acetylsalicylic Acid"@en ;
            skos:broaderTransitive ATC:N02 .


###  http://purl.bioontology.org/ontology/ATC/N02BA51
ATC:N02BA51 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653192" ;
            rdfs:label "Acetylsalicylic Acid, Combinations excl. Psycholeptics"@en ;
            skos:broaderTransitive ATC:N02 .


###  http://purl.bioontology.org/ontology/ATC/N02BE01
ATC:N02BE01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0000970" ;
            rdfs:label "Paracetamol"@en ;
            skos:broaderTransitive ATC:N02 .


###  http://purl.bioontology.org/ontology/ATC/N02BG10
ATC:N02BG10 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006864" ;
            rdfs:label "Cannabinoids"@en ;
            skos:broaderTransitive ATC:N02 .


###  http://purl.bioontology.org/ontology/ATC/N02CC01
ATC:N02CC01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0075632 ;
            rdfs:label "Sumatriptan"@en ;
            skos:broaderTransitive ATC:N02 .


###  http://purl.bioontology.org/ontology/ATC/N02CC03
ATC:N02CC03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0528166" ;
            rdfs:label "Zolmitriptan"@en ;
            skos:broaderTransitive ATC:N02 .


###  http://purl.bioontology.org/ontology/ATC/N03
ATC:N03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003299" ;
        rdfs:label "Antiepileptics"@en ;
        skos:broaderTransitive ATC:N .


###  http://purl.bioontology.org/ontology/ATC/N03AA02
ATC:N03AA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0031412" ;
            rdfs:label "Phenobarbital"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AA04
ATC:N03AA04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0105205" ;
            rdfs:label "Barbexaclone"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AB02
ATC:N03AB02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0031507" ;
            rdfs:label "Phenytoin"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AE01
ATC:N03AE01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0009011" ;
            rdfs:label "Clonazepam"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AF01
ATC:N03AF01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006949" ;
            rdfs:label "Carbamazepine"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AF02
ATC:N03AF02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0069751" ;
            rdfs:label "Oxcarbazepine"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AG01
ATC:N03AG01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042291" ;
            rdfs:label "Valproic Acid"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AG04
ATC:N03AG04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0048044" ;
            rdfs:label "Vigabatrin"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AX09
ATC:N03AX09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0064636" ;
            rdfs:label "Lamotrigine"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AX11
ATC:N03AX11 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0076829" ;
            rdfs:label "Topiramate"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AX12
ATC:N03AX12 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0060926" ;
            rdfs:label "Gabapentin"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AX14
ATC:N03AX14 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0377265" ;
            rdfs:label "Levetiracetam"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AX16
ATC:N03AX16 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0657912" ;
            rdfs:label "Pregabalin"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N03AX24
ATC:N03AX24 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0006863 ;
            rdfs:label "Cannabidiol"@en ;
            skos:broaderTransitive ATC:N03 .


###  http://purl.bioontology.org/ontology/ATC/N04
ATC:N04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003405" ;
        rdfs:label "Anti-Parkinson Drugs"@en ;
        skos:broaderTransitive ATC:N .


###  http://purl.bioontology.org/ontology/ATC/N04BA02
ATC:N04BA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653004" ;
            rdfs:label "Levodopa and Decarboxylase Inhibitor"@en ;
            skos:broaderTransitive ATC:N04 .


###  http://purl.bioontology.org/ontology/ATC/N04BB01
ATC:N04BB01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002403" ;
            rdfs:label "Amantadine"@en ;
            skos:broaderTransitive ATC:N04 .


###  http://purl.bioontology.org/ontology/ATC/N04BC04
ATC:N04BC04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0244821" ;
            rdfs:label "Ropinirole"@en ;
            skos:broaderTransitive ATC:N04 .


###  http://purl.bioontology.org/ontology/ATC/N04BC05
ATC:N04BC05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0074710" ;
            rdfs:label "Pramipexole"@en ;
            skos:broaderTransitive ATC:N04 .


###  http://purl.bioontology.org/ontology/ATC/N04BC06
ATC:N04BC06 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0107994" ;
            rdfs:label "Cabergoline"@en ;
            skos:broaderTransitive ATC:N04 .


###  http://purl.bioontology.org/ontology/ATC/N05
ATC:N05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653516" ;
        rdfs:label "Psycholeptics"@en ;
        skos:broaderTransitive ATC:N .


###  http://purl.bioontology.org/ontology/ATC/N05AF05
ATC:N05AF05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0376160" ;
            rdfs:label "Zuclopenthixol"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05AH03
ATC:N05AH03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0171023" ;
            rdfs:label "Olanzapine"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05AH04
ATC:N05AH04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0123091" ;
            rdfs:label "Quetiapine"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05AX12
ATC:N05AX12 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0299792 ;
            rdfs:label "Aripiprazole"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05AX13
ATC:N05AX13 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0753678" ;
            rdfs:label "Paliperidone"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05B
ATC:N05B rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:PharmacologicSubstance ;
         dcterms:conformsTo UMLS:C0040616 ;
         rdfs:label "Anxiolytics"@en ;
         skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05BA01
ATC:N05BA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0012010" ;
            rdfs:label "Diazepam"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05BA06
ATC:N05BA06 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0024002 ;
            rdfs:label "Lorazepam"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05BA08
ATC:N05BA08 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006213" ;
            rdfs:label "Bromazepam"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05BA09
ATC:N05BA09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0055891" ;
            rdfs:label "Clobazam"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05BA11
ATC:N05BA11 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032910" ;
            rdfs:label "Prazepam"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05BA12
ATC:N05BA12 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002333" ;
            rdfs:label "Alprazolam"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05BA19
ATC:N05BA19 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0059862" ;
            rdfs:label "Etizolam"@en ;
            skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05C
ATC:N05C rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:PharmacologicSubstance ;
         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020592" ;
         rdfs:label "Hypnotics and Sedatives"@en ;
         skos:broaderTransitive ATC:N05 .


###  http://purl.bioontology.org/ontology/ATC/N05CD01
ATC:N05CD01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0016375" ;
            rdfs:label "Flurazepam"@en ;
            skos:broaderTransitive ATC:N05C .


###  http://purl.bioontology.org/ontology/ATC/N05CD05
ATC:N05CD05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040879" ;
            rdfs:label "Triazolam"@en ;
            skos:broaderTransitive ATC:N05C .


###  http://purl.bioontology.org/ontology/ATC/N05CD09
ATC:N05CD09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0054151" ;
            rdfs:label "Brotizolam"@en ;
            skos:broaderTransitive ATC:N05C .


###  http://purl.bioontology.org/ontology/ATC/N05CF02
ATC:N05CF02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0078839" ;
            rdfs:label "Zolpidem"@en ;
            skos:broaderTransitive ATC:N05C .


###  http://purl.bioontology.org/ontology/ATC/N05CH01
ATC:N05CH01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0025219" ;
            rdfs:label "Melatonin"@en ;
            skos:broaderTransitive ATC:N05C .


###  http://purl.bioontology.org/ontology/ATC/N06
ATC:N06 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653540" ;
        rdfs:label "Psychoanaleptics"@en ;
        skos:broaderTransitive ATC:N .


###  http://purl.bioontology.org/ontology/ATC/N06A
ATC:N06A rdf:type owl:NamedIndividual ,
                  skos:Concept ,
                  bto:PharmacologicSubstance ;
         dcterms:conformsTo UMLS:C0003289 ;
         rdfs:label "Antidepressants"@en ;
         skos:broaderTransitive ATC:N06 .


###  http://purl.bioontology.org/ontology/ATC/N06AA09
ATC:N06AA09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002600" ;
            rdfs:label "Amitriptyline"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AB03
ATC:N06AB03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0016365" ;
            rdfs:label "Fluoxetine"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AB04
ATC:N06AB04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0008845" ;
            rdfs:label "Citalopram"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AB05
ATC:N06AB05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0070122" ;
            rdfs:label "Paroxetine"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AB06
ATC:N06AB06 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0074393" ;
            rdfs:label "Sertraline"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AB10
ATC:N06AB10 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1099456" ;
            rdfs:label "Escitalopram"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AX05
ATC:N06AX05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040805" ;
            rdfs:label "Trazodone"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AX11
ATC:N06AX11 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0049506" ;
            rdfs:label "Mitrazapine"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AX16
ATC:N06AX16 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0078569" ;
            rdfs:label "Venlafaxine"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AX18
ATC:N06AX18 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0168388" ;
            rdfs:label "Reboxetine"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AX21
ATC:N06AX21 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0245561 ;
            rdfs:label "Duloxetine"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06AX23
ATC:N06AX23 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1880288 ;
            rdfs:label "Desvenlafaxine"@en ;
            skos:broaderTransitive ATC:N06 .


###  http://purl.bioontology.org/ontology/ATC/N06AX26
ATC:N06AX26 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C3661282 ;
            rdfs:label "Vertioxetine"@en ;
            skos:broaderTransitive ATC:N06A .


###  http://purl.bioontology.org/ontology/ATC/N06BA07
ATC:N06BA07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0066677" ;
            rdfs:label "Modafinil"@en ;
            skos:broaderTransitive ATC:N06 .


###  http://purl.bioontology.org/ontology/ATC/N06BX12
ATC:N06BX12 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001040" ;
            rdfs:label "Acetylcarnitine"@en ;
            skos:broaderTransitive ATC:N06 .


###  http://purl.bioontology.org/ontology/ATC/N06CA01
ATC:N06CA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653016" ;
            rdfs:label "Amitriptyline and Psycholeptics"@en ;
            skos:broaderTransitive ATC:N06 .


###  http://purl.bioontology.org/ontology/ATC/N06DA03
ATC:N06DA03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0649350" ;
            rdfs:label "Rivastigmine"@en ;
            skos:broaderTransitive ATC:N06 .


###  http://purl.bioontology.org/ontology/ATC/N07
ATC:N07 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653848" ;
        rdfs:label "Other Nervous System Drugs"@en ;
        skos:broaderTransitive ATC:N .


###  http://purl.bioontology.org/ontology/ATC/N07BB04
ATC:N07BB04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0027360" ;
            rdfs:label "Naltrexone"@en ;
            skos:broaderTransitive ATC:N07 .


###  http://purl.bioontology.org/ontology/ATC/N07CA01
ATC:N07CA01 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005301" ;
            rdfs:label "Betahistine"@en ;
            skos:broaderTransitive ATC:N07 .


###  http://purl.bioontology.org/ontology/ATC/N07CA02
ATC:N07CA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0008803" ;
            rdfs:label "Cinnarizine"@en ;
            skos:broaderTransitive ATC:N07 .


###  http://purl.bioontology.org/ontology/ATC/N07CA03
ATC:N07CA03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0016295" ;
            rdfs:label "Flunarizine"@en ;
            skos:broaderTransitive ATC:N07 .


###  http://purl.bioontology.org/ontology/ATC/N07CA52
ATC:N07CA52 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653100" ;
            rdfs:label "Cinnarizine, Combinations"@en ;
            skos:broaderTransitive ATC:N07 .


###  http://purl.bioontology.org/ontology/ATC/N07XX02
ATC:N07XX02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0073379" ;
            rdfs:label "Riluzole"@en ;
            skos:broaderTransitive ATC:N07 .


###  http://purl.bioontology.org/ontology/ATC/N07XX07
ATC:N07XX07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0000477" ;
            rdfs:label "Fampridine"@en ;
            skos:broaderTransitive ATC:N07 .


###  http://purl.bioontology.org/ontology/ATC/P
ATC:P rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653620" ;
      rdfs:label "Antiparastic Products, Insecticides and Repllents"@en .


###  http://purl.bioontology.org/ontology/ATC/P01
ATC:P01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003416" ;
        rdfs:label "Antiprotozoals"@en ;
        skos:broaderTransitive ATC:P .


###  http://purl.bioontology.org/ontology/ATC/P01BA02
ATC:P01BA02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020336" ;
            rdfs:label "Hydroxychloroquine"@en ;
            skos:broaderTransitive ATC:P01 .


###  http://purl.bioontology.org/ontology/ATC/P02
ATC:P02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003158" ;
        rdfs:label "Anthelmintics"@en ;
        skos:broaderTransitive ATC:P .


###  http://purl.bioontology.org/ontology/ATC/P03
ATC:P03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653591" ;
        rdfs:label "Ectoparasiticides, incl. Scabicides, Insecticides and Repellents"@en ;
        skos:broaderTransitive ATC:P .


###  http://purl.bioontology.org/ontology/ATC/R
ATC:R rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0282686" ;
      rdfs:label "Respiratory System"@en .


###  http://purl.bioontology.org/ontology/ATC/R01
ATC:R01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653410" ;
        rdfs:label "Nasal Preparations"@en ;
        skos:broaderTransitive ATC:R .


###  http://purl.bioontology.org/ontology/ATC/R02
ATC:R02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653754" ;
        rdfs:label "Throat Preparations"@en ;
        skos:broaderTransitive ATC:R .


###  http://purl.bioontology.org/ontology/ATC/R03
ATC:R03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653498" ;
        rdfs:label "Drugs for Obstructive Airway Diseases"@en ;
        skos:broaderTransitive ATC:R .


###  http://purl.bioontology.org/ontology/ATC/R03AC03
ATC:R03AC03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0039542 ;
            rdfs:label "Terbutaline"@en ;
            skos:broaderTransitive ATC:R03 .


###  http://purl.bioontology.org/ontology/ATC/R03AK07
ATC:R03AK07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1276807 ;
            rdfs:label "Formoterol and Budesonide"@en ;
            skos:broaderTransitive ATC:R03 .


###  http://purl.bioontology.org/ontology/ATC/R03BA05
ATC:R03BA05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0082607 ;
            rdfs:label "Fluticasone"@en ;
            skos:broaderTransitive ATC:R03 .


###  http://purl.bioontology.org/ontology/ATC/R03BB04
ATC:R03BB04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1306772 ;
            rdfs:label "Tiotropium Bromide"@en ;
            skos:broaderTransitive ATC:R03 .


###  http://purl.bioontology.org/ontology/ATC/R03CC02
ATC:R03CC02 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0001927 ;
            rdfs:label "Salbutamol"@en ;
            skos:broaderTransitive ATC:R03 .


###  http://purl.bioontology.org/ontology/ATC/R03DC03
ATC:R03DC03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C0298130 ;
            rdfs:label "Montelukast"@en ;
            skos:broaderTransitive ATC:R03 .


###  http://purl.bioontology.org/ontology/ATC/R05
ATC:R05 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1511537" ;
        rdfs:label "Cough and Cold Preparations"@en ;
        skos:broaderTransitive ATC:R .


###  http://purl.bioontology.org/ontology/ATC/R06
ATC:R06 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653763" ;
        rdfs:label "Antihistamines for Systemic Use"@en ;
        skos:broaderTransitive ATC:R .


###  http://purl.bioontology.org/ontology/ATC/R06AB04
ATC:R06AB04 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0008281" ;
            rdfs:label "Chlorphenamine"@en ;
            skos:broaderTransitive ATC:R06 .


###  http://purl.bioontology.org/ontology/ATC/R06AD03
ATC:R06AD03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0039865" ;
            rdfs:label "Thiethylperazine"@en ;
            skos:broaderTransitive ATC:R06 .


###  http://purl.bioontology.org/ontology/ATC/R06AE07
ATC:R06AE07 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0055147" ;
            rdfs:label "Cetirizine"@en ;
            skos:broaderTransitive ATC:R06 .


###  http://purl.bioontology.org/ontology/ATC/R06AE09
ATC:R06AE09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1174893 ;
            rdfs:label "Levocetirizine"@en ;
            skos:broaderTransitive ATC:R06 .


###  http://purl.bioontology.org/ontology/ATC/R07
ATC:R07 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653833" ;
        rdfs:label "Other Respiratory System Products"@en ;
        skos:broaderTransitive ATC:R .


###  http://purl.bioontology.org/ontology/ATC/S
ATC:S rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3654000" ;
      rdfs:label "Sensory Organs"@en .


###  http://purl.bioontology.org/ontology/ATC/S01
ATC:S01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2013096" ;
        rdfs:label "Ophthalmologicals"@en ;
        skos:broaderTransitive ATC:S .


###  http://purl.bioontology.org/ontology/ATC/S01EE05
ATC:S01EE05 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo UMLS:C1451502 ;
            rdfs:label "Tafluprost"@en ;
            skos:broaderTransitive ATC:S01 .


###  http://purl.bioontology.org/ontology/ATC/S02
ATC:S02 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653485" ;
        rdfs:label "Otologicals"@en ;
        skos:broaderTransitive ATC:S .


###  http://purl.bioontology.org/ontology/ATC/S03
ATC:S03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653568" ;
        rdfs:label "Ophthalmologicals and Otologicals Products"@en ;
        skos:broaderTransitive ATC:S .


###  http://purl.bioontology.org/ontology/ATC/V
ATC:V rdf:type owl:NamedIndividual ,
               skos:Concept ,
               bto:PharmacologicSubstance ;
      dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3540763" ;
      rdfs:label "Various"@en .


###  http://purl.bioontology.org/ontology/ATC/V01
ATC:V01 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002092" ;
        rdfs:label "Allergens"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/ATC/V03
ATC:V03 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653767" ;
        rdfs:label "All Other Therapeutic Products"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/ATC/V03AF03
ATC:V03AF03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0731033" ;
            rdfs:label "Calcium Folinate"@en ;
            skos:broaderTransitive ATC:V03 .


###  http://purl.bioontology.org/ontology/ATC/V04
ATC:V04 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        rdfs:label "Diagnostic Agents"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/ATC/V06
ATC:V06 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653491" ;
        rdfs:label "General Nutrients"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/ATC/V07
ATC:V07 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653748" ;
        rdfs:label "All Other Non-Therapeutic Products"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/ATC/V08
ATC:V08 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0009924" ;
        rdfs:label "Contrast Media"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/ATC/V09
ATC:V09 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0360048" ;
        rdfs:label "Diagnostic Radiopharmaceuticals"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/ATC/V10
ATC:V10 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0358509" ;
        rdfs:label "Therapeutic Radiopharmaceuticals"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/ATC/V20
ATC:V20 rdf:type owl:NamedIndividual ,
                 skos:Concept ,
                 bto:PharmacologicSubstance ;
        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3653515" ;
        rdfs:label "Surgical Dressings"@en ;
        skos:broaderTransitive ATC:V .


###  http://purl.bioontology.org/ontology/SNOMEDCT/107769006
<http://purl.bioontology.org/ontology/SNOMEDCT/107769006> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0186318" ;
                                                          rdfs:comment "Surgical procedure involving an upper extremity."@en ;
                                                          rdfs:label "Operative Procedure on Upper Extremity"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/107784002
<http://purl.bioontology.org/ontology/SNOMEDCT/107784002> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0187763" ;
                                                          rdfs:comment "Surgical procedure involiving a lower extremity."@en ;
                                                          rdfs:label "Surgical Procedure on Lower Extremity"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/110469002
<http://purl.bioontology.org/ontology/SNOMEDCT/110469002> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0195324" ;
                                                          rdfs:comment "The excision of a cone of tissue, especially of the CERVIX UTERI. [Definition Source: MSH]"@en ;
                                                          rdfs:label "Cone Biopsy"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/112902005
<http://purl.bioontology.org/ontology/SNOMEDCT/112902005> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          rdfs:comment "The surgical removal of part of bladder."@en ;
                                                          rdfs:label "Partial Cystectomy"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/1144987003
<http://purl.bioontology.org/ontology/SNOMEDCT/1144987003> rdf:type owl:NamedIndividual ,
                                                                    skos:Concept ,
                                                                    bto:DiseaseDisorderOrFinding ;
                                                           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C5546135" ;
                                                           rdfs:comment "The absence of menses in a woman who has achieved reproductive age due to disorder of pituitary gland. [Partial Defintion Source: NCI"@en ;
                                                           rdfs:label "Amenorrhea due to Pituitary Dysfunction"@en ;
                                                           skos:broaderTransitive NCIT:C61443 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/118445002
<http://purl.bioontology.org/ontology/SNOMEDCT/118445002> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1293110" ;
                                                          rdfs:comment "Surgical removal of bening neoplasm."@en ;
                                                          rdfs:label "Excision of Benign Neoplasm"@en ;
                                                          skos:broaderTransitive <http://purl.bioontology.org/ontology/SNOMEDCT/370612006> .


###  http://purl.bioontology.org/ontology/SNOMEDCT/13619001
<http://purl.bioontology.org/ontology/SNOMEDCT/13619001> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040145" ;
                                                         rdfs:comment "Surgery to remover part or all of the thyroid gland. [Definition Source: NCI]"@en ;
                                                         rdfs:label "Thyroid Gland Excision"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/14045001
<http://purl.bioontology.org/ontology/SNOMEDCT/14045001> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:Group ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0043157" ;
                                                         rdfs:comment "A person having origins in any of the original peoples of Europe, the Middle East, or North Africa. (OMB) [Definition Source: NCI]"@en ;
                                                         rdfs:label "Caucasian"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/177250006
<http://purl.bioontology.org/ontology/SNOMEDCT/177250006> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0198542" ;
                                                          rdfs:comment "Surgical removal of excess abdominal skin and fat and tightening of the ABDOMINAL WALL. Abdominoplasty may include LIPECTOMY of INTRA-ABDOMINAL FAT, tightening of the ABDOMINAL MUSCLES, and re-creation of the UMBILICUS. [Definition Source: MSH]"@en ;
                                                          rdfs:label "Abdominoplasty"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/18167009
<http://purl.bioontology.org/ontology/SNOMEDCT/18167009> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0337824" ;
                                                         rdfs:comment "Denotes a person with ancestral origins are in any of the countries of Africa. [Definition Source: NCI]"@en ;
                                                         rdfs:label "Black African"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/183005
<http://purl.bioontology.org/ontology/SNOMEDCT/183005> rdf:type owl:NamedIndividual ,
                                                                skos:Concept ,
                                                                bto:DiseaseDisorderOrFinding ;
                                                       dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0271893" ;
                                                       rdfs:comment "The autoimmune inability of the bone marrow to produce hematopoietic elements. [Definition Source: NCI]"@en ;
                                                       rdfs:label "Autoimmune Pancytopenia"@en ;
                                                       skos:broaderTransitive NCIT:C34889 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/193093009
<http://purl.bioontology.org/ontology/SNOMEDCT/193093009> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:DiseaseDisorderOrFinding ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0376175" ;
                                                          rdfs:comment "A syndrome characterized by the acute onset of unilateral FACIAL PARALYSIS which progresses over a 2-5 day period. Weakness of the orbicularis oculi muscle and resulting incomplete eye closure may be associated with corneal injury. Pain behind the ear often precedes the onset of paralysis. This condition may be associated with HERPESVIRUS 1, HUMAN infection of the facial nerve. (Adams et al., Principles of Neurology, 6th ed, p1376) [Defintion Source: MSH]"@en ;
                                                          rdfs:label "Bell's Palsy"@en ;
                                                          skos:broaderTransitive NCIT:C26769 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/202708005
<http://purl.bioontology.org/ontology/SNOMEDCT/202708005> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:DiseaseDisorderOrFinding ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0281899" ;
                                                          rdfs:comment "Lumbar Hernia [Definition Source: MedDRA]"@en ;
                                                          rdfs:label "Prolapsed Lumbar Intervertebral Disc"@en ;
                                                          skos:broaderTransitive NCIT:C34685 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/20805001
<http://purl.bioontology.org/ontology/SNOMEDCT/20805001> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo UMLS:C0189054 ;
                                                         rdfs:comment "Rhinoseptoplasty, also known as rhino septoplasty or septorhinoplasty, is a nose job procedure that makes cosmetic changes while realigning a malformed nasal septum. [Defintion Source: themodernplasticsurgery]"@en ;
                                                         rdfs:label "Rhinoseptoplasty"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/21371007
<http://purl.bioontology.org/ontology/SNOMEDCT/21371007> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0198482" ;
                                                         rdfs:comment "A surgical procedure located in the abdomnial region."@en ;
                                                         rdfs:label "Operation on Abdominal Region"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/23056005
<http://purl.bioontology.org/ontology/SNOMEDCT/23056005> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:DiseaseDisorderOrFinding ;
                                                         dcterms:conformsTo UMLS:C0036396 ;
                                                         rdfs:comment "Pain in the lower back and hip radiating in the distribution of the sciatic nerve. [HPO:probinson, PMID:17872935] (HPO)"@en ;
                                                         rdfs:label "Sciatica"@en ;
                                                         skos:broaderTransitive NCIT:C2991 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/232717009
<http://purl.bioontology.org/ontology/SNOMEDCT/232717009> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0010055" ;
                                                          rdfs:comment "Surgery performed to bypass partially or completely occluded coronary arteries, thereby increasing the blood supply of the heart. [Definition Source: NCI]"@en ;
                                                          rdfs:label "Coronary Artery Bypass Graft"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/23344004
<http://purl.bioontology.org/ontology/SNOMEDCT/23344004> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:DiseaseDisorderOrFinding ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0401119" ;
                                                         rdfs:comment "Lumbar Hernia [Definition Source: SNOMEDCT]"@en ;
                                                         rdfs:label "Lumbar Hernia"@en ;
                                                         skos:broaderTransitive NCIT:C34685 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/233935004
<http://purl.bioontology.org/ontology/SNOMEDCT/233935004> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:DiseaseDisorderOrFinding ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0524702" ;
                                                          rdfs:comment "Pulmonary embolism is caused by emboli, which have originated from venous thrombi, travelling to and occluding the arteries of the lung. [PMID:29770793]"@en ;
                                                          rdfs:label "Pulmonary Thromboembolism"@en ;
                                                          skos:broaderTransitive NCIT:C28195 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/235159007
<http://purl.bioontology.org/ontology/SNOMEDCT/235159007> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          rdfs:comment "The placement of a feeding tube through the abdominal wall into the stomach using an endoscope. [Definition Source: NCI]"@en ;
                                                          rdfs:label "Percutaneous Endoscopic Gastrostomy (PEG)"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/236825001
<http://purl.bioontology.org/ontology/SNOMEDCT/236825001> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0403848" ;
                                                          rdfs:comment "Drainage of abscess of Barholin's gland."@en ;
                                                          rdfs:label "Drainage of Bartholin's Abscess"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/236886002
<http://purl.bioontology.org/ontology/SNOMEDCT/236886002> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020699" ;
                                                          rdfs:comment "A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). [Definition source: NCI]"@en ;
                                                          rdfs:label "Hysterectomy"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/24079001
<http://purl.bioontology.org/ontology/SNOMEDCT/24079001> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:DiseaseDisorderOrFinding ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011615" ;
                                                         rdfs:comment "A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. [Definition Source: MSH]"@en ;
                                                         rdfs:label "Atopic Dermatitis"@en ;
                                                         skos:broaderTransitive NCIT:C3001 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/250980009
<http://purl.bioontology.org/ontology/SNOMEDCT/250980009> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          rdfs:comment "The conversion of one cardiac rhythm or electrical pattern to another, almost always from an abnormal to a normal one, by pharmacologic means using medications or by electrical cardioversion using a defibrillator. [Definition Source: NCI]"@en ;
                                                          rdfs:label "Cardioversion"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/26212005
<http://purl.bioontology.org/ontology/SNOMEDCT/26212005> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo UMLS:C0003506 ;
                                                         rdfs:label "Replacement of Aortic Valve"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/300009002
<http://purl.bioontology.org/ontology/SNOMEDCT/300009002> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0576748" ;
                                                          rdfs:comment "Surgical removal of acoustic neuroma."@en ;
                                                          rdfs:label "Removal of Acoustic Neuroma"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/300025007
<http://purl.bioontology.org/ontology/SNOMEDCT/300025007> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0576763" ;
                                                          rdfs:comment "Surgical removal of basal cell carcinoma."@en ;
                                                          rdfs:label "Excision of Basal Cell Carcinoma"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/302870006
<http://purl.bioontology.org/ontology/SNOMEDCT/302870006> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:DiseaseDisorderOrFinding ;
                                                          dcterms:conformsTo UMLS:C0020557 ;
                                                          rdfs:comment "A condition of elevated levels of TRIGLYCERIDES in the blood. [Definition Source: MSH]"@en ;
                                                          rdfs:label "Hypertriglyceridaemia"@en ;
                                                          skos:broaderTransitive NCIT:C2991 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/303011007
<http://purl.bioontology.org/ontology/SNOMEDCT/303011007> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:DiseaseDisorderOrFinding ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0027947" ;
                                                          rdfs:comment "A decrease in the number of NEUTROPHILS found in the blood. [Definition Source: MSH]"@en ;
                                                          rdfs:label "Neutropenic Disorder"@en ;
                                                          skos:broaderTransitive NCIT:C3367 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/311801003
<http://purl.bioontology.org/ontology/SNOMEDCT/311801003> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          rdfs:comment "Any approach involiving the head and neck region."@en ;
                                                          rdfs:label "Head and Neck Approaches"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/315240009
<http://purl.bioontology.org/ontology/SNOMEDCT/315240009> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:Group ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005680" ;
                                                          rdfs:comment "A person having origins in the original peoples of sub-Saharan Africa or the Caribbean."@en ;
                                                          rdfs:label "Black (ethnic group)"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/315280000
<http://purl.bioontology.org/ontology/SNOMEDCT/315280000> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:Group ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1282531" ;
                                                          rdfs:comment "A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam. (OMB) [Definition Source: NCI]"@en ;
                                                          rdfs:label "Asian (ethnic group)"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/35926005
<http://purl.bioontology.org/ontology/SNOMEDCT/35926005> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo UMLS:C0188184 ;
                                                         rdfs:label "Repair of Knee Cruciate Ligaments"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/370612006
<http://purl.bioontology.org/ontology/SNOMEDCT/370612006> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1299802" ;
                                                          rdfs:comment "The surgical removal of a neoplasm."@en ;
                                                          rdfs:label "Excision of Neoplasm"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/37340000
<http://purl.bioontology.org/ontology/SNOMEDCT/37340000> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:DiseaseDisorderOrFinding ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0085084" ;
                                                         rdfs:comment "Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) [Definition Source: MSH]"@en ;
                                                         rdfs:label "Motor Neuron Disease"@en ;
                                                         skos:broaderTransitive NCIT:C4802 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/38102005
<http://purl.bioontology.org/ontology/SNOMEDCT/38102005> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0008320" ;
                                                         rdfs:comment "Surgical removal of the gallbladder. [Definition Source: NCI]"@en ;
                                                         rdfs:label "Cholecystectomy"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/385487005
<http://purl.bioontology.org/ontology/SNOMEDCT/385487005> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0524832" ;
                                                          rdfs:comment "Any surgery performed inside the thoracic cavity. [Definition Source: NCI]"@en ;
                                                          rdfs:label "Surgical Procedure on Thorax"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/387731002
<http://purl.bioontology.org/ontology/SNOMEDCT/387731002> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo UMLS:C0022983 ;
                                                          rdfs:comment "A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots. [Defintion Source: MSH]"@en ;
                                                          rdfs:label "Laminectomy"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/389145006
<http://purl.bioontology.org/ontology/SNOMEDCT/389145006> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:DiseaseDisorderOrFinding ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0155877" ;
                                                          rdfs:comment "Allergic Asthma"@en ;
                                                          rdfs:label "Allergic Asthma"@en ;
                                                          skos:broaderTransitive NCIT:C28397 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/414408004
<http://purl.bioontology.org/ontology/SNOMEDCT/414408004> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:Group ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0086409" ;
                                                          rdfs:comment "A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term, \"Spanish origin\" can be used in addition to \"Hispanic or Latino\". (OMB) [Definition Source: NCI]"@en ;
                                                          rdfs:label "Hispanic"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/428297005
<http://purl.bioontology.org/ontology/SNOMEDCT/428297005> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1997755" ;
                                                          rdfs:comment "Surgical removal of a cyst."@en ;
                                                          rdfs:label "Excision of Cyst"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/428402007
<http://purl.bioontology.org/ontology/SNOMEDCT/428402007> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1997868" ;
                                                          rdfs:comment "Lumbo-sacral spine surgery"@en ;
                                                          rdfs:label "Operative Procedure on Lumbosacral Spinal Structure"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/428490009
<http://purl.bioontology.org/ontology/SNOMEDCT/428490009> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1997463" ;
                                                          rdfs:comment "Surgical procedure on the cervical spine."@en ;
                                                          rdfs:label "Surgical Procedure on Cervical Spine"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/428614005
<http://purl.bioontology.org/ontology/SNOMEDCT/428614005> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1997608" ;
                                                          rdfs:comment "Thoracic spine surgery."@en ;
                                                          rdfs:label "Operative Procedure on Thoracic Spinal Structure"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/442338001
<http://purl.bioontology.org/ontology/SNOMEDCT/442338001> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0017125" ;
                                                          rdfs:comment "Surgical procedure in which the STOMACH is transected high on the body. The resulting small proximal gastric pouch is joined to any parts of the SMALL INTESTINE by an end-to-side SURGICAL ANASTOMOSIS, depending on the amounts of intestinal surface being bypasses. This procedure is used frequently in the treatment of MORBID OBESITY by limiting the size of functional STOMACH, food intake, and food absorption. [Definition Source: MSH]"@en ;
                                                          rdfs:label "Gastryc Bypass"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/445968009
<http://purl.bioontology.org/ontology/SNOMEDCT/445968009> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2960489" ;
                                                          rdfs:comment "Surgical insertion of intrathecal access system for drug delivery."@en ;
                                                          rdfs:label "Insertion of Implantable Intrathecal Access System"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/447139008
<http://purl.bioontology.org/ontology/SNOMEDCT/447139008> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:DiseaseDisorderOrFinding ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0159870" ;
                                                          rdfs:comment "A closed fracture of the tibia."@en ;
                                                          rdfs:label "Closed Fracture of Tibia"@en ;
                                                          skos:broaderTransitive NCIT:C99083 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/50172003
<http://purl.bioontology.org/ontology/SNOMEDCT/50172003> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo UMLS:C0186045 ;
                                                         rdfs:comment "Lumbar spinal fusion is surgery to join, or fuse, two or more vertebrae in the low back. The surgery is also called arthrodesis. [Defintion Source: myhealth.alberta.ca]"@en ;
                                                         rdfs:label "Lumbar Spinal Fusion"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/55622001
<http://purl.bioontology.org/ontology/SNOMEDCT/55622001> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0189343" ;
                                                         rdfs:comment "Surgical formation of an opening into the trachea through the neck, or the opening so created. [Definition Source: MSH]"@en ;
                                                         rdfs:label "Emergency Tracheostomy"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/609637006
<http://purl.bioontology.org/ontology/SNOMEDCT/609637006> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3661975" ;
                                                          rdfs:comment "Pelvic surgery."@en ;
                                                          rdfs:label "Procedure on Pelvic Region of Trunk"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/700074001
<http://purl.bioontology.org/ontology/SNOMEDCT/700074001> rdf:type owl:NamedIndividual ,
                                                                   skos:Concept ,
                                                                   bto:SurgicalType ;
                                                          dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3839771" ;
                                                          rdfs:comment "Surgical removal of dermatofibroma."@en ;
                                                          rdfs:label "Excision of dermatofibroma"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/73589001
<http://purl.bioontology.org/ontology/SNOMEDCT/73589001> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:DiseaseDisorderOrFinding ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0021818" ;
                                                         rdfs:comment "Herniated Disc [Definition Source: MedDRA]"@en ;
                                                         rdfs:label "Intervertebral Disc Prolapse"@en ;
                                                         skos:broaderTransitive NCIT:C34685 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/74146001
<http://purl.bioontology.org/ontology/SNOMEDCT/74146001> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0194475" ;
                                                         rdfs:comment "Surgical repair of bladder"@en ;
                                                         rdfs:label "Repair of Bladder"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/80146002
<http://purl.bioontology.org/ontology/SNOMEDCT/80146002> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003611" ;
                                                         rdfs:comment "Surgical removal of the vermiform appendix. [Definition Source: NCI]"@en ;
                                                         rdfs:label "Appendectomy"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/882784691000119100
<http://purl.bioontology.org/ontology/SNOMEDCT/882784691000119100> rdf:type owl:NamedIndividual ,
                                                                            skos:Concept ,
                                                                            bto:DiseaseDisorderOrFinding ;
                                                                   dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C5244027" ;
                                                                   rdfs:comment "Pneumonia caused by severe acute respiratory syndrome coronavirus 2 [Definition Source: SNOMEDCT]"@en ;
                                                                   rdfs:label "Pneumonia Caused By SARS-CoV-2"@en ;
                                                                   skos:broaderTransitive NCIT:C3333 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/89743005
<http://purl.bioontology.org/ontology/SNOMEDCT/89743005> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:DiseaseDisorderOrFinding ;
                                                         dcterms:conformsTo UMLS:C0948163 ;
                                                         rdfs:comment "Non-specific white matter changes in the BRAIN, often seen after age 65. Changes include loss of AXONS; MYELIN pallor, GLIOSIS, loss of ependymal cells, and enlarged perivascular spaces. Leukoaraiosis is a risk factor for DEMENTIA and CEREBROVASCULAR DISORDERS. [Definition Source: MSH]"@en ;
                                                         rdfs:label "Leukoaraiosis"@en ;
                                                         skos:broaderTransitive NCIT:C3367 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/90199006
<http://purl.bioontology.org/ontology/SNOMEDCT/90199006> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:SurgicalType ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040771" ;
                                                         rdfs:comment "Prostate tissue removal via a cystoscope. [Definition Source: NCI]"@en ;
                                                         rdfs:label "Transurethral Prostatectomy"@en .


###  http://purl.bioontology.org/ontology/SNOMEDCT/90460009
<http://purl.bioontology.org/ontology/SNOMEDCT/90460009> rdf:type owl:NamedIndividual ,
                                                                  skos:Concept ,
                                                                  bto:DiseaseDisorderOrFinding ;
                                                         dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0027531" ;
                                                         rdfs:comment "General or unspecified injuries to the neck. It includes injuries to the skin, muscles, and other soft tissues of the neck. [Defintion Source: MSH]"@en ;
                                                         rdfs:label "Neck Trauma"@en ;
                                                         skos:broaderTransitive NCIT:C36282 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/9389005
<http://purl.bioontology.org/ontology/SNOMEDCT/9389005> rdf:type owl:NamedIndividual ,
                                                                 skos:Concept ,
                                                                 bto:DiseaseDisorderOrFinding ;
                                                        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019357" ;
                                                        rdfs:comment "A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed) [Defintion Source: MSH]"@en ;
                                                        rdfs:label "Herpes Simplex Keratitis"@en ;
                                                        skos:broaderTransitive NCIT:C155871 ,
                                                                               NCIT:C26805 .


###  http://purl.bioontology.org/ontology/SNOMEDCT/9429009
<http://purl.bioontology.org/ontology/SNOMEDCT/9429009> rdf:type owl:NamedIndividual ,
                                                                 skos:Concept ,
                                                                 bto:SurgicalType ;
                                                        dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0017193" ;
                                                        rdfs:comment "Surgical procedures involving the STOMACH and sometimes the lower ESOPHAGUS to correct anatomical defects, or to treat MORBID OBESITY by reducing the size of the stomach. There are several subtypes of bariatric gastroplasty, such as vertical banded gastroplasty, silicone ring vertical gastroplasty, and horizontal banded gastroplasty. [Definition Source: MSH]"@en ;
                                                        rdfs:label "Gastroplasty"@en .


###  http://purl.obolibrary.org/obo/NCIT_C100023
NCIT:C100023 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0581375" ;
             rdfs:comment "There was greater than or equal to 50% stenosis (reduction in cross-sectional area) in two coronary arteries (or greater than or equal to 50% stenosis in the left main coronary artery). (ACC) [Definition Source: NCI]"@en ;
             rdfs:label "Two Vessel Coronary Disease"@en ;
             skos:broaderTransitive NCIT:C2931 .


###  http://purl.obolibrary.org/obo/NCIT_C100104
NCIT:C100104 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0037088" ;
             rdfs:comment "Objective evidence of disease perceptible to the examining practitioner (sign) and subjective evidence of disease perceived by the patient (symptom). [Definition Source: NCI]"@en ;
             rdfs:label "Sign or Symptom"@en ;
             skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C100808
NCIT:C100808 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:KinshipType ;
             dcterms:conformsTo UMLS:C3639750 ;
             rdfs:comment "Any individual related biologically or legally to another individual and considered two degrees removed from the immediate family as in the case of cousins. [Definition Source: NCI]"@en ;
             rdfs:label "Third Degree Relative"@en .


###  http://purl.obolibrary.org/obo/NCIT_C101214
NCIT:C101214 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0080178" ;
             rdfs:comment "A congenital neural tube defect in which vertebrae are not fully formed. It results in the protrusion of the spinal cord through the opening of the vertebrae. [Definition Source: NCI]"@en ;
             rdfs:label "Spina Bifida"@en ;
             skos:broaderTransitive NCIT:C27586 .


###  http://purl.obolibrary.org/obo/NCIT_C101398
NCIT:C101398 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:Gene ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1428691" ;
             rdfs:comment "This gene may play a role in cell death. [Definition Source: NCI]"@en ;
             rdfs:label "C9orf72 Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C101491
NCIT:C101491 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:Gene ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1420393" ;
             rdfs:comment "This gene is involved in signal transduction. [Definition Source: NCI]"@en ;
             rdfs:label "SQSTM1 Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C111201
NCIT:C111201 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:KinshipType ;
             dcterms:conformsTo UMLS:C3830065 ;
             rdfs:comment "A male who shares with his sibling the genetic makeup inherited from both of the biological parents. [Definition Source: NCI]"@en ;
             rdfs:label "Brother"@en ;
             skos:broaderTransitive NCIT:C21481 .


###  http://purl.obolibrary.org/obo/NCIT_C111202
NCIT:C111202 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:KinshipType ;
             dcterms:conformsTo UMLS:C3827310 ;
             rdfs:comment "A female who shares with her sibling the genetic makeup inherited from both of the biological parents. [Definition Source: NCI]"@en ;
             rdfs:label "Sister"@en ;
             skos:broaderTransitive NCIT:C21481 .


###  http://purl.obolibrary.org/obo/NCIT_C112175
NCIT:C112175 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002994" ;
             rdfs:comment "Rapid swelling of the deep layers of the skin due to transient vascular leakage of serous fluid. [Definition Source: NCI][attribution: NICHD]"@en ;
             rdfs:label "Angioedema"@en ;
             skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C112183
NCIT:C112183 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005741" ;
             rdfs:comment "Inflammation of the eyelids near the eyelashes. [Definition Source: NCI][attribution: NICHD]"@en ;
             rdfs:label "Blepharitits"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C112208
NCIT:C112208 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3541994" ;
             rdfs:comment "A potentially life-threatening hypersensitivity reaction to a pharmacologic substance that is characterized by rash, lymphadenopathy, fever, hematologic abnormalities and involvement of one or more internal organs. [Definition Source: NCI][attribution: NICHD]"@en ;
             rdfs:label "Drug Hypersensitivity Syndrome"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C112357
NCIT:C112357 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0026394" ;
             rdfs:comment "A species of enveloped and brick-shaped viruses in the Poxviridae family and Molluscipoxvirus genus. The genome is composed of non-segmented, linear double-stranded DNA. Molluscum contagiosum viruses are found in humans and can cause the disease Molluscum contagiosum. Molluscum contagiosum viruses are transmitted via direct person-to-person contact and contact with infected fomites. [Definition Source: NCI]"@en ;
             rdfs:label "Molluscum Contagiosum Virus"@en .


###  http://purl.obolibrary.org/obo/NCIT_C112833
NCIT:C112833 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040262" ;
             rdfs:comment "A skin condition characterized by hypopigmented, pink or tan, confetti-like, discrete and confluent scaly macules distributed on the chest, shoulders and upper back. [Definition Source: NCI]"@en ;
             rdfs:label "Tinea Versicolor"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C114830
NCIT:C114830 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo UMLS:C0042870 ;
             rdfs:comment "Abnormally low level of 25-hydroxyvitamin D in the blood. [Definition Source: NCI]"@en ;
             rdfs:label "Vitamin D Deficiency"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C115958
NCIT:C115958 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0521618" ;
             rdfs:comment "Narrowing of the luminal diameter of one or both ureters due to intrinsic factors. [Definition Source: NCI]"@en ;
             rdfs:label "Ureteral Stenosis"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C116369
NCIT:C116369 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003126" ;
             rdfs:comment "Inability to smell. [Definition Source: NCI]"@en ;
             rdfs:label "Anosmia"@en ;
             skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C116374
NCIT:C116374 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2364111" ;
             rdfs:comment "Inability to taste. [Definition Source: NCI]"@en ;
             rdfs:label "Ageusia"@en ;
             skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C116585
NCIT:C116585 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0018946" ;
             rdfs:comment "A collection of blood between the dura mater and the brain. [Definition Source: NCI]"@en ;
             rdfs:label "Subdural Hematoma"@en ;
             skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C116921
NCIT:C116921 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0338656" ;
             rdfs:comment "Diminished mental function. [Definition Source: NCI]"@en ;
             rdfs:label "Cognitive Impariment"@en ;
             skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C117005
NCIT:C117005 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0154723" ;
             rdfs:comment "A migraine disorder characterized by episodes that are preceded by focal neurological symptoms. [Definition Source: NCI]"@en ;
             rdfs:label "Migraine With Aura"@en ;
             skos:broaderTransitive NCIT:C89715 .


###  http://purl.obolibrary.org/obo/NCIT_C117084
NCIT:C117084 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032768" ;
             rdfs:comment "Pain that occurs after the disappearance of herpes zoster infection lesions. [Definition Source: NCI]"@en ;
             rdfs:label "Post-Herpetic Neuralgia"@en ;
             skos:broaderTransitive NCIT:C4876 .


###  http://purl.obolibrary.org/obo/NCIT_C118723
NCIT:C118723 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005747" ;
             rdfs:comment "Involuntary twitching of the eyelid. [Definition Source: NCI]"@en ;
             rdfs:label "Blepharospasm"@en ;
             skos:broaderTransitive NCIT:C36282 .


###  http://purl.obolibrary.org/obo/NCIT_C119640
NCIT:C119640 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:Gene ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1424774" ;
             rdfs:comment "This gene plays a role in both neuroprotection and Golgi maintenance [Definition Source: NCI]"@en ;
             rdfs:label "OPTN Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C122419
NCIT:C122419 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0259797" ;
             rdfs:comment "A wound received from the teeth of a dog. [Definition Source: NCI]"@en ;
             rdfs:label "Dog Bite"@en ;
             skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C122822
NCIT:C122822 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo UMLS:C0008350 ;
             rdfs:comment "The presence of calculi in the gallbladder. [Definition Source: NCI]"@en ;
             rdfs:label "Cholelithiasis"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C122875
NCIT:C122875 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:Gene ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1413935" ;
             rdfs:comment "This gene is involved in the modulation of retrograde transport of cytoplasmic organelles and vesicles. [Definition Source: NCI]"@en ;
             rdfs:label "DCTN1 Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C123215
NCIT:C123215 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0520575" ;
             rdfs:comment "Sudden onset pyelonephritis. [Definition Source: NCI][attribution: NICHD]"@en ;
             rdfs:label "Acute Pyelonephritis"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C123330
NCIT:C123330 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo UMLS:C0024437 ;
             rdfs:comment "Loss of vision in the central portion of the retina (macula), secondary to retinal degeneration. [Definition Source: NCI]"@en ;
             rdfs:label "Macular Degeneration"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C12401
NCIT:C12401 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015392" ;
            rdfs:comment "The organ of sight or vision. [Definition Source: NCI]"@en ;
            rdfs:label "Eye"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12419
NCIT:C12419 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0018670" ;
            rdfs:comment "The anterior and superior part of a human bearing the mouth, the brain and sensory organs. [Definition Source: NCI]"@en ;
            rdfs:label "Head"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12429
NCIT:C12429 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015385" ;
            rdfs:comment "A body region referring to an upper or lower extremity. [Definition Source: NCI]"@en ;
            rdfs:label "Limb"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12431
NCIT:C12431 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005953" ;
            rdfs:comment "The tissue occupying the spaces of bone. It consists of blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes. [Definition Source: NCI]"@en ;
            rdfs:label "Bone Marrow"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12439
NCIT:C12439 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006104" ;
            rdfs:comment "An organ composed of grey and white matter containing billions of neurons that is the center for intelligence and reasoning. It is protected by the bony cranium. [Definition Source: NCI]"@en ;
            rdfs:label "Brain"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12441
NCIT:C12441 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006121" ;
            rdfs:comment "Three sections, the midbrain, pons and medulla oblongata, that are located at the base of the brain. The brain stem regulates the central nervous system, and is vital as a conduit for motor and sensory innervations. [Definition Source: NCI]"@en ;
            rdfs:label "Brain Stem"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12445
NCIT:C12445 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007765" ;
            rdfs:comment "The portion of the brain located at the base of the skull that is responsible for balance, equilibrium and movement. [Definition Source: NCI]"@en ;
            rdfs:label "Cerebellum"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12464
NCIT:C12464 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0037925" ;
            rdfs:comment "The elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge. [Definition Source: NCI][attribution: On-line Medical Dictionary]"@en ;
            rdfs:label "Spinal Cord"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12512
NCIT:C12512 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1522407" ;
            rdfs:comment "The part of the brain that is located superior to the tentorium cerebelli. [Definition Source: NCI]"@en ;
            rdfs:label "Supratentorial Brain"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12664
NCIT:C12664 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0230168" ;
            rdfs:comment "The cavity located between the lungs and pelvis. It contains the lower esophagus, stomach, pancreas, intestines, liver, gallbladder and spleen. [Definition Source: NCI]"@en ;
            rdfs:label "Abdomen"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12671
NCIT:C12671 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1140618" ;
            rdfs:comment "The region of the body that includes the arm, the forearm, and hand. [Definition Source: NCI]"@en ;
            rdfs:label "Upper Extremity"@en ;
            skos:broaderTransitive NCIT:C12429 .


###  http://purl.obolibrary.org/obo/NCIT_C12742
NCIT:C12742 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0023216" ;
            rdfs:comment "The limb that is composed of the hip, thigh, leg and foot. [Definition Source: NCI]"@en ;
            rdfs:label "Lower Extremity"@en ;
            skos:broaderTransitive NCIT:C12429 .


###  http://purl.obolibrary.org/obo/NCIT_C12767
NCIT:C12767 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0030797" ;
            rdfs:comment "The bony, basin-shaped structure formed by the hipbones and the base of the backbone supporting the lower limbs in humans. [Definition Source: NCI]"@en ;
            rdfs:label "Pelvis"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12799
NCIT:C12799 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0817096" ;
            rdfs:comment "The division of the body lying between the neck and the abdomen. [Definition Source: NCI]"@en ;
            rdfs:label "Thorax"@en .


###  http://purl.obolibrary.org/obo/NCIT_C128405
NCIT:C128405 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0276139" ;
             rdfs:comment "Pericarditis that is caused by an infection with a viral agent. [Definition Source: NCI]"@en ;
             rdfs:label "Viral Pericarditis"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C12892
NCIT:C12892 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0581619" ;
            rdfs:comment "The portion of the spinal cord located in the cervical region. [Definition Source: NCI]"@en ;
            rdfs:label "Cervical Spinal Cord"@en .


###  http://purl.obolibrary.org/obo/NCIT_C12894
NCIT:C12894 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0581620" ;
            rdfs:comment "The portion of the spinal cord located in the thoracic region. [Definition Source: NCI]"@en ;
            rdfs:label "Thoracic Spinal Cord"@en .


###  http://purl.obolibrary.org/obo/NCIT_C129644
NCIT:C129644 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0700502" ;
             rdfs:comment "Hypothyroidism, the cause of which is not present at birth. [Definition Source: NCI]"@en ;
             rdfs:label "Acquired Hypothyroidism"@en ;
             skos:broaderTransitive NCIT:C26800 .


###  http://purl.obolibrary.org/obo/NCIT_C129933
NCIT:C129933 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo UMLS:C0154682 ;
             rdfs:comment "A progressive neurodegenerative disorder affecting upper motor neurons, characterized by progressive muscle weakness. [Definition Source: NCI]"@en ;
             rdfs:label "Primary Lateral Sclerosis"@en ;
             skos:broaderTransitive <http://purl.bioontology.org/ontology/SNOMEDCT/37340000> .


###  http://purl.obolibrary.org/obo/NCIT_C12998
NCIT:C12998 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0037949" ;
            rdfs:comment "A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. [Definition Source: NCI]"@en ;
            rdfs:label "Vertebral Column"@en .


###  http://purl.obolibrary.org/obo/NCIT_C13063
NCIT:C13063 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0027530" ;
            rdfs:comment "The region that connects the head to the rest of the body. [Definition Source: NCI]"@en ;
            rdfs:label "Neck"@en .


###  http://purl.obolibrary.org/obo/NCIT_C142296
NCIT:C142296 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:AnatomicalSite ;
             rdfs:comment "The space between the L4 and L5 vertebrae. [Definition Source: NCI]"@en ;
             rdfs:label "L4-L5 Intervertebral Space"@en .


###  http://purl.obolibrary.org/obo/NCIT_C148427
NCIT:C148427 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo UMLS:C1142169 ;
             rdfs:comment "The reemergence of acute myeloid leukemia after a period of remission. [Definition Source: NCI]"@en ;
             rdfs:label "Recurrent Acute Myeloid Leukemia"@en ;
             skos:broaderTransitive NCIT:C3171 .


###  http://purl.obolibrary.org/obo/NCIT_C1505
NCIT:C1505 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:PharmacologicSubstance ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0242295" ;
           rdfs:comment "Oral preparations containing dietary ingredient(s) intended to supplement the diet. Dietary ingredients include vitamins, minerals, herbs, amino acids, extracts and metabolites. [Definition Source: NCI]"@en ;
           rdfs:label "Dietary Supplement"@en ;
           skos:note "Dietary supplements do not have an ATC but they belong to the GMP class 4AA2F30."@en .


###  http://purl.obolibrary.org/obo/NCIT_C15304
NCIT:C15304 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:TherapeuticProcedureType ;
            rdfs:comment "A procedure that collects plasma from the peripheral blood while returning the rest to the donor. [Definition Source: NCI]"@en ;
            rdfs:label "Plasmapheresis"@en ;
            skos:broaderTransitive bto:ImmunoactiveDrugs .


###  http://purl.obolibrary.org/obo/NCIT_C15342
NCIT:C15342 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:SurgicalType ;
            dcterms:conformsTo UMLS:C0040732 ;
            rdfs:comment "Transference of a tissue or organ within an individual, between individuals of the same species, or between individuals of different species. [Definition Source: NCI]"@en ;
            rdfs:label "Transplantation"@en .


###  http://purl.obolibrary.org/obo/NCIT_C15402
NCIT:C15402 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:SurgicalType ;
            dcterms:conformsTo UMLS:C0195324 ;
            rdfs:comment "Surgical removal of a cone-shaped portion of tissue from the uterine cervix. [Definition Source: NCI]"@en ;
            rdfs:label "Conization"@en .


###  http://purl.obolibrary.org/obo/NCIT_C15454
NCIT:C15454 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:SurgicalType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1512343" ;
            rdfs:comment "Any surgery involving a structure in the head and neck region. [Definition Source: NCI]"@en ;
            rdfs:label "Head and Neck Surgery"@en ;
            skos:broaderTransitive <http://purl.bioontology.org/ontology/SNOMEDCT/311801003> .


###  http://purl.obolibrary.org/obo/NCIT_C155871
NCIT:C155871 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019348" ;
             rdfs:comment "An infection that is caused by herpes simplex virus. [Definition Source: NCI]"@en ;
             rdfs:label "Herpes Simplex Virus Infection"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C156767
NCIT:C156767 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007117" ;
             rdfs:comment "A carcinoma involving the basal cells. [Definition Source: NCI]"@en ;
             rdfs:label "Basal Cell Carcinoma"@en ;
             skos:broaderTransitive NCIT:C2916 .


###  http://purl.obolibrary.org/obo/NCIT_C157942
NCIT:C157942 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C4324621" ;
             rdfs:comment "The use of opioids that results in the development of a dependency that adversely affects an individual's life. [Definition Source: NCI]"@en ;
             rdfs:label "Opioid Use Disorder"@en .


###  http://purl.obolibrary.org/obo/NCIT_C157959
NCIT:C157959 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0155862" ;
             rdfs:comment "Pneumonia that is attributed to the bacteria Streptococcus pneumonia. [Definition Source: NCI]"@en ;
             rdfs:label "Pneumococcal Pneumonia"@en ;
             skos:broaderTransitive NCIT:C3333 .


###  http://purl.obolibrary.org/obo/NCIT_C171133
NCIT:C171133 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C5203670" ;
             rdfs:comment "An acute infection of the respiratory tract that is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Based on currently available information, SARS-CoV-2 is thought to mainly spread from person to person through respiratory droplets. Typically, there is a two- to 14-day incubation period and infected persons can present with no symptoms or mild to severe fever, dry cough, fatigue, and difficulty breathing. Dysgeusia, anosmia, and gastrointestinal and flu-like symptoms have also been reported. Older adults and persons of any age who have serious underlying medical conditions may be of higher risk for severe illness, including secondary infections, respiratory failure, and multi-organ dysfunction. [Definition Source: NCI]"@en ;
             rdfs:label "COVID-19 Infection"@en ;
             skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C171204
NCIT:C171204 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0039980" ;
             rdfs:comment "Trauma to the chest. [Definition Source: NCI]"@en ;
             rdfs:label "Thoracic Trauma"@en ;
             skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C171457
NCIT:C171457 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:TherapeuticProcedureType ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2349740" ;
             rdfs:comment "A type of mechanical ventilation procedure that uses a non-invasive means, such as a face mask or nasal mask, to deliver oxygenated air into the lungs. [Definition Source: NCI]"@en ;
             rdfs:label "Non-Invasive Mechanical Ventilation (NIV)"@en .


###  http://purl.obolibrary.org/obo/NCIT_C180747
NCIT:C180747 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo UMLS:C3805092 ;
             rdfs:comment "A change in the nucleotide sequence of the MTHFR gene. [Definition Source: NCI]"@en ;
             rdfs:label "MTHFR Gene Mutation"@en .


###  http://purl.obolibrary.org/obo/NCIT_C185645
NCIT:C185645 rdf:type owl:NamedIndividual ,
                      skos:Concept ,
                      bto:DiseaseDisorderOrFinding ;
             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0235378" ;
             rdfs:comment "Toxicity that impairs or damages the liver. [Definition Source: NCI]"@en ;
             rdfs:label "Hepatic Toxicity"@en ;
             skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C19811
NCIT:C19811 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1519210" ;
            rdfs:comment "Any relative who is two meioses away from a particular individual in a family; a relative with whom one quarter of an individual's genes is shared (i.e., grandparent, grandchild, uncle, aunt, nephew, niece, half-sibling) (from Genetics Home Reference glossary) [Definition Source: NCI]"@en ;
            rdfs:label "Second Degree Relative"@en .


###  http://purl.obolibrary.org/obo/NCIT_C21009
NCIT:C21009 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:SurgicalType ;
            dcterms:conformsTo UMLS:C0206078 ;
            rdfs:comment "Surgical excision of an intervertebral disc. Often performed for pain relief. [Definition Source: NCI]"@en ;
            rdfs:label "Discectomy"@en .


###  http://purl.obolibrary.org/obo/NCIT_C21481
NCIT:C21481 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1517194" ;
            rdfs:comment "Any relative who is one meiosis away from a particular individual in a family; a relative with whom one half of an individual's genes is shared (i.e., parent, sibling, offspring) (from Genetics Home Reference glossary) [Definition Source: NCI]"@en ;
            rdfs:label "First Degree Relative"@en .


###  http://purl.obolibrary.org/obo/NCIT_C24845
NCIT:C24845 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:Gene ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1336579" ;
            rdfs:comment "This gene plays a role in the immune response and signal transduction. [Definition Source: NCI]"@en ;
            rdfs:label "TBK1 Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C25165
NCIT:C25165 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo UMLS:C0337552 ;
            rdfs:comment "A female human offspring. [Definition Source: NCI]"@en ;
            rdfs:label "Daughter"@en ;
            skos:broaderTransitive NCIT:C21481 .


###  http://purl.obolibrary.org/obo/NCIT_C25174
NCIT:C25174 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo UMLS:C0015671 ;
            rdfs:comment "A male parent. [Definition Source: NCI]"@en ;
            rdfs:label "Father"@en ;
            skos:broaderTransitive NCIT:C21481 .


###  http://purl.obolibrary.org/obo/NCIT_C25189
NCIT:C25189 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo UMLS:C0026591 ;
            rdfs:comment "A female parent. [Definition Source: NCI]"@en ;
            rdfs:label "Mother"@en ;
            skos:broaderTransitive NCIT:C21481 .


###  http://purl.obolibrary.org/obo/NCIT_C25205
NCIT:C25205 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0037683" ;
            rdfs:comment "A male human offspring. [Definition Source: NCI]"@en ;
            rdfs:label "Son"@en ;
            skos:broaderTransitive NCIT:C21481 .


###  http://purl.obolibrary.org/obo/NCIT_C264
NCIT:C264 rdf:type owl:NamedIndividual ,
                   skos:Concept ,
                   bto:TherapeuticProcedureType ;
          rdfs:comment "Medicine to stop, prevent, or control seizures (convulsions). [Definition Source: NCI]" ;
          rdfs:label "Anticonvulsant Agent"@en ;
          skos:broaderTransitive bto:DrugsForOtherDiseases .


###  http://purl.obolibrary.org/obo/NCIT_C26682
NCIT:C26682 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0000737" ;
            rdfs:comment "Painful sensation in the abdominal region. [Definition Source: NCI]"@en ;
            rdfs:label "Abdominal Pain"@en ;
            skos:broaderTransitive NCIT:C4876 .


###  http://purl.obolibrary.org/obo/NCIT_C26704
NCIT:C26704 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004626" ;
            rdfs:comment "Acute infection of the lung parenchyma caused by bacteria (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila). Signs and symptoms include productive cough, fever, chills, shortness of breath, and chest pain. [Definition Source: NCI]"@en ;
            rdfs:label "Bacterial Pneumonia"@en ;
            skos:broaderTransitive NCIT:C3333 .


###  http://purl.obolibrary.org/obo/NCIT_C26714
NCIT:C26714 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007570" ;
            rdfs:comment "An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. [Definition Source: NCI]"@en ;
            rdfs:label "Celiac Disease"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26717
NCIT:C26717 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007933" ;
            rdfs:comment "An eyelid cyst caused by the blockage of a meibomian gland. [Definition Source: NCI]"@en ;
            rdfs:label "Chalazion"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26747
NCIT:C26747 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011860" ;
            rdfs:comment "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity. [Definition Source: NCI]"@en ;
            rdfs:label "Type 2 Diabetes Mellitus"@en ;
            skos:broaderTransitive NCIT:C2985 .


###  http://purl.obolibrary.org/obo/NCIT_C26769
NCIT:C26769 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015469" ;
            rdfs:comment "Partial or complete paralysis of the facial muscles of one side of a person's face. It is caused by damage to the seventh cranial nerve. It is usually temporary but it may recur. [Definition Source: NCI]"@en ;
            rdfs:label "Cranial Nerve VII Palsy"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26774
NCIT:C26774 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015802" ;
            rdfs:comment "A traumatic or pathologic injury to the femur in which the continuity of the femur is broken. [Definition Source: NCI]"@en ;
            rdfs:label "Femur Fracture"@en ;
            skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C26780
NCIT:C26780 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0017152" ;
            rdfs:comment "Inflammation of the stomach. [Definition Source: NCI]"@en ;
            rdfs:label "Gastritis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26781
NCIT:C26781 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0017168 ;
            rdfs:comment "A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa. [Definition Source: NCI]"@en ;
            rdfs:label "Gastroesophageal Reflux Disease"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26782
NCIT:C26782 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0017601" ;
            rdfs:comment "Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor. [Definition Source: NCI]"@en ;
            rdfs:label "Glaucoma"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26800
NCIT:C26800 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020676" ;
            rdfs:comment "Abnormally low levels of thyroid hormone. [Definition Source: NCI][attribution: NICHD]"@en ;
            rdfs:label "Hypothyroidism"@en ;
            skos:broaderTransitive NCIT:C26893 .


###  http://purl.obolibrary.org/obo/NCIT_C26805
NCIT:C26805 rdf:type owl:NamedIndividual ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0022568" ;
            rdfs:comment "Inflammation of the cornea. [Definition Source: NCI]"@en ;
            rdfs:label "Keratitis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26806
NCIT:C26806 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0022578" ;
            rdfs:comment "A degenerative, structural disorder of the eye, characterized by a cone-shaped protrusion of the cornea. It may lead to visual disturbances. [Definition Source: NCI]"@en ;
            rdfs:label "Keratoconus"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26815
NCIT:C26815 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0023524" ;
            rdfs:comment "A progressive demyelination within the central nervous system associated with reactivation of a latent JC virus infection. [Definition Source: NCI]"@en ;
            rdfs:label "Progressive Multifocal Leukoencephalopathy"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26816
NCIT:C26816 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0750394" ;
            rdfs:comment "A laboratory test result indicating a decreased number of white blood cells in the peripheral blood. [Definition Source: NCI]"@en ;
            rdfs:label "Leukopenia"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C26823
NCIT:C26823 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0853986" ;
            rdfs:comment "An abnormally small number of lymphocytes in the circulating blood. [Definition Source: NCI]"@en ;
            rdfs:label "Lymphopenia"@en ;
            skos:broaderTransitive NCIT:C26816 .


###  http://purl.obolibrary.org/obo/NCIT_C26835
NCIT:C26835 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0027765 ;
            rdfs:comment "A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. [Definition Source: NCI]"@en ;
            rdfs:label "Nervous System Disorder"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26845
NCIT:C26845 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0030567" ;
            rdfs:comment "A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression. [Definition Source: NCI]"@en ;
            rdfs:label "Parkinson's Disease"@en ;
            skos:broaderTransitive NCIT:C79593 .


###  http://purl.obolibrary.org/obo/NCIT_C26855
NCIT:C26855 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0032026 ;
            rdfs:comment "A mild, self-limited skin disorder that is most commonly seen in children and young adults. It is characterized by an initial large round spot on the chest, abdomen, or back, often referred to as a herald patch, that is usually followed within a week by a distinctive pattern of similar but smaller papules on the torso, arms, and legs. There may also be itching, especially when overheated. [Definition Source: NCI]"@en ;
            rdfs:label "Pityriasis Rosea"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26874
NCIT:C26874 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0035305" ;
            rdfs:comment "An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision. [Definition Source: NCI]"@en ;
            rdfs:label "Retinal Detachment"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26883
NCIT:C26883 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1527336" ;
            rdfs:comment "An autoimmune disorder affecting the salivary and lacrimal glands. Morphologically, it is characterized by the presence of lymphocytic and plasmacytic infiltrates which cause destruction of these glands. It results in dry mouth and dry eyes. It may be associated with the presence of other autoimmune disorders, including rheumatoid arthritis and lupus erythematosus. [Definition Source: NCI]"@en ;
            rdfs:label "Sjogren Syndrome"@en ;
            skos:broaderTransitive NCIT:C2889 .


###  http://purl.obolibrary.org/obo/NCIT_C26893
NCIT:C26893 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040128" ;
            rdfs:comment "A non-neoplastic or neoplastic disorder that affects the thyroid gland. Representative examples include hyperthyroidism, hypothyroidism, thyroiditis, follicular adenoma, and carcinoma. [Definition Source: NCI]"@en ;
            rdfs:label "Thyroid Gland Disorder"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26894
NCIT:C26894 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040147" ;
            rdfs:comment "Inflammation of the thyroid gland. This category includes Hashimoto thyroiditis, Riedel thyroiditis, acute thyroiditis, subacute thyroiditis, and radiation-induced thyroiditis. [Definition Source: NCI]"@en ;
            rdfs:label "Thyroiditis"@en ;
            skos:broaderTransitive NCIT:C26893 .


###  http://purl.obolibrary.org/obo/NCIT_C26905
NCIT:C26905 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0042018 ;
            rdfs:comment "A concretion in the urinary tract. [Definition Source: NCI]"@en ;
            rdfs:label "Urinary Stone"@en .


###  http://purl.obolibrary.org/obo/NCIT_C26915
NCIT:C26915 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042900" ;
            rdfs:comment "Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes. [Definition Source: NCI][attribution: NICHD]"@en ;
            rdfs:label "Vitiligo"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26921
NCIT:C26921 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0085594" ;
            rdfs:comment "Shivering secondary to a febrile process. [Definition Source: NCI]"@en ;
            rdfs:label "Fever Chills"@en ;
            skos:broaderTransitive NCIT:C4876 .


###  http://purl.obolibrary.org/obo/NCIT_C26934
NCIT:C26934 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0149523" ;
            rdfs:comment "An acute infection of the bladder. It is usually caused by bacteria. Signs and symptoms include increased frequency of urination, pain or burning during urination, fever, cloudy or bloody urine, and suprapubic pain. [Definition Source: NCI]"@en ;
            rdfs:label "Acute Cystitis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26948
NCIT:C26948 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0151905" ;
            rdfs:comment "An increase in the level of alanine aminotransferase in the blood. [Definition Source: NCI]"@en ;
            rdfs:label "Alanine Aminotransferase Increased"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C26952
NCIT:C26952 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0152177" ;
            rdfs:comment "A non-neoplastic or neoplastic disorder affecting the trigeminal nerve (fifth cranial nerve). [Definition Source: NCI]"@en ;
            rdfs:label "Trigeminal Nerve Disorder"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C26989
NCIT:C26989 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0159877" ;
            rdfs:comment "Traumatic or pathological injury to the ankle joint in which the continuity of an ankle bone is broken. Symptoms include pain, swelling, and difficulty moving the affected leg and foot. [Definition Source: NCI]"@en ;
            rdfs:label "Ankle Fracture"@en ;
            skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C27006
NCIT:C27006 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0206061" ;
            rdfs:comment "Inflammation of interstitial lung tissue, usually associated with infection. [Definition Source: NCI]"@en ;
            rdfs:label "Interstitial Pneumonia"@en ;
            skos:broaderTransitive NCIT:C3333 .


###  http://purl.obolibrary.org/obo/NCIT_C27020
NCIT:C27020 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0236100 ;
            rdfs:comment "A non-neoplastic or neoplastic disorder that affects the female genital system. Representative examples of non-neoplastic disorders include infection, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. [Definition Source: NCI]"@en ;
            rdfs:label "Female Reproductive System Disorder"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C27043
NCIT:C27043 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0264490" ;
            rdfs:comment "Life-threatening respiratory failure that develops rapidly. Causes include injury, sepsis, drug overdose, and pancreatitis. It manifests with dyspnea and cyanosis and may lead to cardiovascular shock. [Definition Source: NCI]"@en ;
            rdfs:label "Acute Respiratory Failure"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C27168
NCIT:C27168 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0520679" ;
            rdfs:comment "A disorder characterized by recurrent episodic disruptions of breathing during sleep. It is caused by the intermittent relaxation of pharyngeal muscles leading to the narrowing or complete blockage of the upper airway. This results in compensatory arousal from sleep to breathe again. An anatomically narrow airway from body habitus or enlarged pharyngeal structures may also predispose to obstruction. Clinical presentation usually includes snoring, daytime sleepiness, difficulty concentrating and fatigue. Clinical course may progress to chronic hypoxemia with cardiovascular and cerebrovascular sequelae. [Definition Source: NCI]"@en ;
            rdfs:label "Obstructive Sleep Apnea Syndrome"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C27191
NCIT:C27191 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0677607" ;
            rdfs:comment "An autoimmune disorder caused by the production of autoantibodies against thyroid tissue. There is progressive destruction of the thyroid follicles leading to hypothyroidism. [Definition Source: NCI]"@en ;
            rdfs:label "Hashimoto Thyroiditis"@en ;
            skos:broaderTransitive NCIT:C26894 .


###  http://purl.obolibrary.org/obo/NCIT_C27204
NCIT:C27204 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0035435 ;
            rdfs:comment "Inflammatory and degenerative diseases of connective tissue structures, such as arthritis. [Definition Source: NCI]"@en ;
            rdfs:label "Rheumatologic Disorder"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C27219
NCIT:C27219 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0877203 ;
            rdfs:comment "A respiratory tract infection caused by a virus. Viruses represent the most common causes of upper and lower respiratory tract infections and include rhinoviruses, influenza viruses, parainfluenza viruses, and respiratory syncytial virus. [Definition Source: NCI]"@en ;
            rdfs:label "Viral Respiratory Tract Infection"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C27586
NCIT:C27586 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1335000" ;
            rdfs:comment "Any disorder other than abnormal tissue growth resulting from uncontrolled cell proliferation affecting the nervous system."@en ;
            rdfs:label "Non-Neoplastic Central Nervous System Disorder"@en ;
            skos:broaderTransitive NCIT:C26835 ,
                                   NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C27996
NCIT:C27996 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0027051 ;
            rdfs:comment "Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis. [Definition Source: NCI]"@en ;
            rdfs:label "Myocardial Infarction"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C28195
NCIT:C28195 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040038" ;
            rdfs:comment "Occlusion of the lumen of a vessel by a thrombus that has migrated from a distal site via the blood stream. [Definition Source: NCI]"@en ;
            rdfs:label "Thromboembolism"@en ;
            skos:broaderTransitive NCIT:C2931 .


###  http://purl.obolibrary.org/obo/NCIT_C28286
NCIT:C28286 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0917801 ;
            rdfs:comment "A sleep disorder characterized by difficulty in falling asleep and/or remaining asleep. [Definition Source: NCI]"@en ;
            rdfs:label "Insomnia"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C28381
NCIT:C28381 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1409894" ;
            rdfs:comment "A circular band of muscle that functions to regulate the size of an orifice in the body. [Definition Source: NCI]"@en ;
            rdfs:label "Sphincter"@en .


###  http://purl.obolibrary.org/obo/NCIT_C28397
NCIT:C28397 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004096" ;
            rdfs:comment "A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways. [Definition Source: NCI]"@en ;
            rdfs:label "Asthma"@en ;
            skos:broaderTransitive NCIT:C98541 .


###  http://purl.obolibrary.org/obo/NCIT_C2851
NCIT:C2851 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0001175 ;
           rdfs:comment "A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin lymphoma and Kaposi sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood. [Definition Source: NCI]"@en ;
           rdfs:label "Acquired Immunodeficiency Syndrome (AIDS)"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2852
NCIT:C2852 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001418" ;
           rdfs:comment "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma. [Definition Source: NCI]"@en ;
           rdfs:label "Adenocarcinoma"@en ;
           skos:broaderTransitive NCIT:C2916 .


###  http://purl.obolibrary.org/obo/NCIT_C28539
NCIT:C28539 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:Gene ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1367578" ;
            rdfs:comment "This gene plays a role in the transcriptional activation of androgen responsive genes. [Definition Source: NCI]"@en ;
            rdfs:label "AR Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C2866
NCIT:C2866 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002395" ;
           rdfs:comment "A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. [Definition Source: NCI]"@en ;
           rdfs:label "Alzheimer's Disease"@en ;
           skos:broaderTransitive NCIT:C4786 .


###  http://purl.obolibrary.org/obo/NCIT_C2869
NCIT:C2869 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002871" ;
           rdfs:comment "A reduction in the number of red blood cells, the amount of hemoglobin, and/or the volume of packed red blood cells. Clinically, anemia represents a reduction in the oxygen-transporting capacity of a designated volume of blood, resulting from an imbalance between blood loss (through hemorrhage or hemolysis) and blood production. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. [Definition Source: NCI]"@en ;
           rdfs:label "Anemia"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2875
NCIT:C2875 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           rdfs:comment "Loss of appetite. [Definition Source: NCI]"@en ,
                        "https://uts.nlm.nih.gov/uts/umls/concept/C1971624" ;
           rdfs:label "Anorexia"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2878
NCIT:C2878 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003469" ;
           rdfs:comment "A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. [Definition Source: NCI]"@en ;
           rdfs:label "Anxiety Disorder"@en ;
           skos:broaderTransitive NCIT:C2893 .


###  http://purl.obolibrary.org/obo/NCIT_C2881
NCIT:C2881 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003811" ;
           rdfs:comment "Any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart. [Definition Source: NCI]"@en ;
           rdfs:label "Arrhythmia"@en ;
           skos:broaderTransitive NCIT:C2931 .


###  http://purl.obolibrary.org/obo/NCIT_C2883
NCIT:C2883 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003864" ;
           rdfs:comment "An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain. [Definition Source: NCI]"@en ;
           rdfs:label "Arthritis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2884
NCIT:C2884 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003873" ;
           rdfs:comment "A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor. [Definition Source: NCI]"@en ;
           rdfs:label "Rheumatoid Arthritis"@en ;
           skos:broaderTransitive NCIT:C2883 ,
                                  NCIT:C2889 .


###  http://purl.obolibrary.org/obo/NCIT_C2889
NCIT:C2889 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004364" ;
           rdfs:comment "A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis). [Definition Source: NCI]"@en ;
           rdfs:label "Autoimmune Disease"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2893
NCIT:C2893 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004936" ;
           rdfs:comment "A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [Definition Source: NCI]"@en ;
           rdfs:label "Psychiatric Disorder"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2897
NCIT:C2897 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C1704272 ;
           rdfs:comment "A non-cancerous nodular enlargement of the prostate gland. It is characterized by the presence of epithelial cell nodules, and stromal nodules containing fibrous and smooth muscle elements. It is the most common urologic disorder in men, causing blockage of urine flow. [Definition Source: NCI]"@en ;
           rdfs:label "Benign Prostatic Hyperplasia"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2914
NCIT:C2914 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006852" ;
           rdfs:comment "Infection of the vulva and vagina with a fungus of the genus CANDIDA. It is a disease associated with HIV infection. [Definition Source: NCI]"@en ;
           rdfs:label "Vulvovaginal Candidiasis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2916
NCIT:C2916 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007097" ;
           rdfs:comment "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. [Definition Source: NCI]"@en ;
           rdfs:label "Carcinoma"@en ;
           skos:broaderTransitive NCIT:C9305 .


###  http://purl.obolibrary.org/obo/NCIT_C2920
NCIT:C2920 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007114" ;
           rdfs:comment "A primary or metastatic malignant neoplasm involving the skin. Primary malignant skin neoplasms most often are carcinomas (either basal cell or squamous cell carcinomas) or melanomas. Metastatic malignant neoplasms to the skin include carcinomas and lymphomas. [Definition Source: NCI]"@en ;
           rdfs:label "Malignant Skin Neoplasm"@en ;
           skos:broaderTransitive NCIT:C9305 .


###  http://purl.obolibrary.org/obo/NCIT_C2921
NCIT:C2921 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007117" ;
           rdfs:comment "The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas. [Definition Source: NCI]"@en ;
           rdfs:label "Skin Basal Cell Carcinoma"@en ;
           skos:broaderTransitive NCIT:C156767 .


###  http://purl.obolibrary.org/obo/NCIT_C2922
NCIT:C2922 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007118" ;
           rdfs:comment "A basal cell carcinoma which displays squamous differentiation. The neoplastic cells have more abundant cytoplasm with more marked keratinization than typical basal cell carcinomas. It usually has a more aggressive clinical course compared to typical basal cell carcinoma, and it may produce regional or widespread metastases. [Definition Source: NCI]"@en ;
           rdfs:label "Skin Basosquamous Cell Carcinoma"@en ;
           skos:broaderTransitive NCIT:C2921 .


###  http://purl.obolibrary.org/obo/NCIT_C2931
NCIT:C2931 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007222" ;
           rdfs:comment "A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. [Definition Source: NCI]"@en ;
           rdfs:label "Cardiovascular Disorder"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2955
NCIT:C2955 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0009402 ;
           rdfs:comment "A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas. [Definition Source: NCI]"@en ;
           rdfs:label "Colorectal Carcinoma"@en ;
           skos:broaderTransitive NCIT:C3262 .


###  http://purl.obolibrary.org/obo/NCIT_C2978
NCIT:C2978 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0010709" ;
           rdfs:comment "A sac-like closed membranous structure that may be empty or contain fluid or amorphous material. [Definition Source: NCI]"@en ;
           rdfs:label "Cyst"@en ;
           skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C2982
NCIT:C2982 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011570" ;
           rdfs:comment "A melancholy feeling of sadness and despair. [Definition Source: NCI]"@en ;
           rdfs:label "Depression"@en ;
           skos:broaderTransitive NCIT:C92200 .


###  http://purl.obolibrary.org/obo/NCIT_C2985
NCIT:C2985 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011849" ;
           rdfs:comment "A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization. [Definition Source: NCI]"@en ;
           rdfs:label "Diabetes Mellitus"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2986
NCIT:C2986 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011854" ;
           rdfs:comment "A chronic condition characterized by minimal or absent production of insulin by the pancreas. [Definition Source: NCI][attribution: NICHD]"@en ;
           rdfs:label "Type 1 Diabtes Mellitus"@en ;
           skos:broaderTransitive NCIT:C2889 ,
                                  NCIT:C2985 .


###  http://purl.obolibrary.org/obo/NCIT_C29888
NCIT:C29888 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0026780" ;
            rdfs:comment "A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. [Definition Source: NCI]"@en ;
            rdfs:label "Mumps"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C2991
NCIT:C2991 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0012634" ;
           rdfs:comment "Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. [Definition Source: NCI]"@en ;
           rdfs:label "Disease or Disorder"@en .


###  http://purl.obolibrary.org/obo/NCIT_C3001
NCIT:C3001 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0013595" ;
           rdfs:comment "A form of dermatitis characterized by red, itchy, scaly, or crusty patches that can be chronic or intermittent. [Definition Source: NCI][attribution: NICHD]"@en ;
           rdfs:label "Eczema"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3014
NCIT:C3014 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0014175" ;
           rdfs:comment "The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. [Definition Source: NCI]"@en ;
           rdfs:label "Endometriosis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3020
NCIT:C3020 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0014544" ;
           rdfs:comment "A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions. [Definition Source: NCI]"@en ;
           rdfs:label "Seizure Disorder"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3021
NCIT:C3021 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0014548" ;
           rdfs:comment "A chronic condition characterised by recurrent generalised seizures. [Definition Source: NCI]"@en ;
           rdfs:label "Generalized Epilepsy"@en ;
           skos:broaderTransitive NCIT:C3020 .


###  http://purl.obolibrary.org/obo/NCIT_C3041
NCIT:C3041 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0016045" ;
           rdfs:comment "A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts. [Definition Source: NCI]"@en ;
           rdfs:label "Fibroma"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3079
NCIT:C3079 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0018799 ;
           rdfs:comment "A non-neoplastic or neoplastic disorder that affects the heart and/or the pericardium. Representative examples include endocarditis, pericarditis, atrial myxoma, cardiac myeloid sarcoma, and pericardial malignant mesothelioma. [Definition Source: NCI]"@en ;
           rdfs:label "Heart Disorder"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3086
NCIT:C3086 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0018920" ;
           rdfs:comment "A hemangioma characterized by the presence of cavernous vascular spaces. [Definition Source: NCI]"@en ;
           rdfs:label "Cavernous Hemangioma"@en ;
           skos:broaderTransitive NCIT:C2931 .


###  http://purl.obolibrary.org/obo/NCIT_C3095
NCIT:C3095 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019158" ;
           rdfs:comment "Inflammation of the liver; usually from a viral infection, but sometimes from toxic agents. [Definition Source: NCI]"@en ;
           rdfs:label "Hepatitis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3096
NCIT:C3096 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019159" ;
           rdfs:comment "Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. [Definition Source: NCI]"@en ;
           rdfs:label "Hepatitis A Infection"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3098
NCIT:C3098 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0019196 ;
           rdfs:comment "A viral infection caused by the hepatitis C virus. [Definition Source: NCI]"@en ;
           rdfs:label "Hepatitis C Infection"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3107
NCIT:C3107 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019621" ;
           rdfs:comment "A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001) [Definition Source: NCI]"@en ;
           rdfs:label "Langerhans Cell Histiocytosis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3114
NCIT:C3114 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020517" ;
           rdfs:comment "An immune response that occurs following exposure to an innocuous antigen, but that does not require the presence of preformed antibodies to the antigen. [Definition Source: NCI]"@en ;
           rdfs:label "Hypersensitivity"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3117
NCIT:C3117 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020538" ;
           rdfs:comment "Blood pressure that is abnormally high. [Definition Source: NCI]"@en ;
           rdfs:label "Hypertension"@en ;
           skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C3122
NCIT:C3122 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020546" ;
           rdfs:comment "A severe, acute increase in blood pressure that may result in stroke or myocardial ischemia. [Definition Source: NCI]"@en ;
           rdfs:label "Hypertensive Crisis"@en ;
           skos:broaderTransitive NCIT:C2931 .


###  http://purl.obolibrary.org/obo/NCIT_C3123
NCIT:C3123 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020550" ;
           rdfs:comment "Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor. [Definition Source: NCI]"@en ;
           rdfs:label "Hyperthyroidism"@en ;
           skos:broaderTransitive NCIT:C26893 .


###  http://purl.obolibrary.org/obo/NCIT_C3124
NCIT:C3124 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0020564 ;
           rdfs:comment "Abnormal enlargement of a body part or organ. [Definition Source: NCI]"@en ;
           rdfs:label "Hypertrophy"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3134
NCIT:C3134 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0014511" ;
           rdfs:comment "The most common type of cutaneous cyst. It results from the proliferation of epidermal cells in a circumscribed space within the dermis. It is usually asymptomatic and presents as a firm, round nodule. [Definition Source: NCI]"@en ;
           rdfs:label "Epidermal Inclusion Cyst"@en ;
           skos:broaderTransitive NCIT:C2978 .


###  http://purl.obolibrary.org/obo/NCIT_C3171
NCIT:C3171 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0023467 ;
           rdfs:comment "A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias (AMLs) encompasses four major categories: 1) AML with recurrent genetic abnormalities; 2) AML with multilineage dysplasia; 3) Therapy-related AML; 4) AML not otherwise specified. The required bone marrow or peripheral blood blast percentage for the diagnosis of AML is 20% (WHO classification). [Definition Source: NCI]"@en ;
           rdfs:label "Acute Myeloid Leukemia"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3199
NCIT:C3199 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0024117 ;
           rdfs:comment "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema. [Definition Source: NCI]"@en ;
           rdfs:label "Chronic Obstructive Pulmonary Disease"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3211
NCIT:C3211 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0024305 ;
           rdfs:comment "Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage. [Definition Source: NCI]"@en ;
           rdfs:label "Non-Hodgkin Lymphoma"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3243
NCIT:C3243 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0026769" ;
           rdfs:comment "A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers. [Definition Source: NCI]"@en ;
           rdfs:label "Multiple Sclerosis"@en ;
           skos:broaderTransitive NCIT:C27586 ,
                                  NCIT:C99383 .


###  http://purl.obolibrary.org/obo/NCIT_C3245
NCIT:C3245 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0026946" ;
           rdfs:comment "An infection caused by a fungus. [Definition Source: NCI]"@en ;
           rdfs:label "Fungal Infection"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3262
NCIT:C3262 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0375111" ;
           rdfs:comment "A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. [Definition Source: NCI]"@en ;
           rdfs:label "Neoplasm"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3283
NCIT:C3283 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0028754" ;
           rdfs:comment "Having a high amount of body fat (body mass index [BMI] of 30 or more). [Definition Source: NCI]"@en ;
           rdfs:label "Obesity"@en ;
           skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C3298
NCIT:C3298 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0029456" ;
           rdfs:comment "A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss). [Definition Source: NCI]"@en ;
           rdfs:label "Osteoporosis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3329
NCIT:C3329 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032000" ;
           rdfs:comment "A well-differentiated neuroendocrine neoplasm that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. It has a low frequency of metastatic spread. When metastatic, the term metastatic pituitary neuroendocrine tumor is endorsed instead of pituitary carcinoma. (WHO) [Definition Source: NCI] It has exact synonim: Pituitary Gland Adenoma."@en ;
           rdfs:label "Pituitary Neuroendocrine Tumor"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3331
NCIT:C3331 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032227" ;
           rdfs:comment "Increased amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough, and chest pain. It is usually caused by lung infections, congestive heart failure, pleural and lung tumors, connective tissue disorders, and trauma. [Definition Source: NCI]"@en ;
           rdfs:label "Pleural Effusion"@en ;
           skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C3333
NCIT:C3333 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032285" ;
           rdfs:comment "An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. [Definition Source: NCI]"@en ;
           rdfs:label "Pneumonia"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3346
NCIT:C3346 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0033860" ;
           rdfs:comment "An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp. [Definition Source: NCI][attribution: NICHD]"@en ;
           rdfs:label "Psoriasis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3364
NCIT:C3364 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0036690 ;
           rdfs:comment "The presence of pathogenic microorganisms in the blood stream causing a rapidly progressing systemic reaction that may lead to shock. Symptoms include fever, chills, tachycardia, and increased respiratory rate. It is a medical emergency that requires urgent medical attention. [Definition Source: NCI]"@en ;
           rdfs:label "Septicemia"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3367
NCIT:C3367 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1285578" ;
           rdfs:comment "Clinical, laboratory or molecular evidence, or absence of evidence of disease. [Definition Source: NCI]"@en ;
           rdfs:label "Finding"@en .


###  http://purl.obolibrary.org/obo/NCIT_C3390
NCIT:C3390 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0038454" ;
           rdfs:comment "A sudden loss of neurological function secondary to hemorrhage or ischemia in the brain parenchyma due to a vascular event. [Definition Source: NCI]"@en ;
           rdfs:label "Stroke"@en ;
           skos:broaderTransitive NCIT:C27586 .


###  http://purl.obolibrary.org/obo/NCIT_C3408
NCIT:C3408 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0392386" ;
           rdfs:comment "A laboratory test result indicating that there is an abnormally small number of platelets in the circulating blood. [Definition Source: NCI]"@en ;
           rdfs:label "Thrombocytopenia"@en ;
           skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C3418
NCIT:C3418 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040558" ;
           rdfs:comment "A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii. [Definition Source: NCI]"@en ;
           rdfs:label "Toxoplasmosis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3432
NCIT:C3432 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0042109 ;
           rdfs:comment "A transient, itchy skin eruption characterized by wheals with pale interiors and red margins. [Definition Source: NCI]"@en ;
           rdfs:label "Urticaria"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3434
NCIT:C3434 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042133" ;
           rdfs:comment "A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. [Definition Source: NCI]"@en ;
           rdfs:label "Uterine Corpus Leiomyoma"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34360
NCIT:C34360 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001627" ;
            rdfs:comment "A genetic disorder characterized by defects in the synthesis of cortisol and/or aldosterone, resulting in hyperplasia of the adrenal cortical cells. [Definition Source: NCI]"@en ;
            rdfs:label "Congenital Adrenal Hyperplasia"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34373
NCIT:C34373 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002736" ;
            rdfs:comment "A neurodegenerative disorder characterized by progressive degeneration of the motor neurons of the central nervous system. It results in weakness and atrophy of the muscles which leads to an inability to initiate and control voluntary movements. [Definition Source: NCI]"@en ;
            rdfs:label "Amyotrophic Lateral Sclerosis"@en ;
            skos:broaderTransitive <http://purl.bioontology.org/ontology/SNOMEDCT/37340000> ,
                                   NCIT:C4802 .


###  http://purl.obolibrary.org/obo/NCIT_C34379
NCIT:C34379 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002881" ;
            rdfs:comment "A congenital hemolytic anemia caused by defects of the erythrocyte membrane, enzyme deficiencies, or hemoglobinopathies. [Definition Source: NCI]"@en ;
            rdfs:label "Hereditary Hemolytic Anemia"@en ;
            skos:broaderTransitive NCIT:C2869 .


###  http://purl.obolibrary.org/obo/NCIT_C34423
NCIT:C34423 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0005586" ;
            rdfs:comment "A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression. [Definition Source: NCI]"@en ;
            rdfs:label "Bipolar Disorder"@en ;
            skos:broaderTransitive NCIT:C92200 .


###  http://purl.obolibrary.org/obo/NCIT_C34486
NCIT:C34486 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0434579" ;
            rdfs:comment "A closed dislocation of the shoulder [Definition Source: NCI]"@en ;
            rdfs:label "Closed Dislocation of Shoulder"@en ;
            skos:broaderTransitive NCIT:C35020 .


###  http://purl.obolibrary.org/obo/NCIT_C34499
NCIT:C34499 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0009438" ;
            rdfs:comment "The presence of one or more stones in the common bile duct. They are composed either of cholesterol or, less commonly, calcium salts and bilirubin. [Definition Source: NCI]"@en ;
            rdfs:label "Common Bile Duct Stone"@en .


###  http://purl.obolibrary.org/obo/NCIT_C3457
NCIT:C3457 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0079731 ;
           rdfs:comment "The most common type of non-Hodgkin lymphoma. It includes the most frequently seen morphologic variants which are: diffuse large B-cell lymphoma, follicular lymphoma, small lymphocytic lymphoma and marginal zone B-cell lymphoma. [Definition Source: NCI]"@en ;
           rdfs:label "B-Cell Non-Hodgkin Lymphoma"@en ;
           skos:broaderTransitive NCIT:C3211 .


###  http://purl.obolibrary.org/obo/NCIT_C34607
NCIT:C34607 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015702" ;
            rdfs:comment "A condition associated with glucose-6-phosphate dehydrogenase deficiency, which is characterized by hemolysis. [Definition Source: NCI]"@en ;
            rdfs:label "Favism"@en ;
            skos:broaderTransitive NCIT:C2869 .


###  http://purl.obolibrary.org/obo/NCIT_C34632
NCIT:C34632 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0017160" ;
            rdfs:comment "An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting. [Definition Source: NCI]"@en ;
            rdfs:label "Gastroenteritits"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34660
NCIT:C34660 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0018674" ;
            rdfs:comment "A traumatic injury to the head. [Definition Source: NCI]"@en ;
            rdfs:label "Head Trauma"@en ;
            skos:broaderTransitive NCIT:C36282 .


###  http://purl.obolibrary.org/obo/NCIT_C34661
NCIT:C34661 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0018681" ;
            rdfs:comment "Pain in various parts of the head, not confined to the area of distribution of any nerve. [Definition Source: NCI]"@en ;
            rdfs:label "Headache"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C34685
NCIT:C34685 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019270" ;
            rdfs:comment "The protrusion of part of an organ or fibroadipose tissue through an abnormal opening. [Definition Source: NCI]"@en ;
            rdfs:label "Hernia"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3469
NCIT:C3469 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0013312" ;
           rdfs:comment "A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males. [Definition Source: NCI] It has exact synonim: Dupuytren Contracture; Palmar Fibromatosis; Dupuytren's Contracture."@en ;
           rdfs:label "Palmar Fibromatosis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34690
NCIT:C34690 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019294" ;
            rdfs:comment "The protrusion of a sac-like structure containing fibroadipose tissue through an abnormal opening in the inguinal region. [Definition Source: NCI]"@en ;
            rdfs:label "Inguinal Hernia"@en ;
            skos:broaderTransitive NCIT:C34685 .


###  http://purl.obolibrary.org/obo/NCIT_C34695
NCIT:C34695 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019345" ;
            rdfs:comment "A lesion caused by type 1 or type 2 herpes simplex virus, involving the oralfacial region. [Definition Source: NCI]"@en ;
            rdfs:label "Cold Sore"@en ;
            skos:broaderTransitive NCIT:C155871 .


###  http://purl.obolibrary.org/obo/NCIT_C34726
NCIT:C34726 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0021345" ;
            rdfs:comment "A clinical syndrome of fever, sore throat, fatigue, and lymphadenopathy caused by infection with the Epstein-Barr virus. Subsequent physical findings may include hepatomegaly, palatal petechiae, jaundice, uvular edema, and splenomegaly. [Definition Source: NCI]"@en ;
            rdfs:label "Infectious Mononucleosis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34733
NCIT:C34733 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0021847" ;
            rdfs:comment "Ileus of the intestine in which there is no mechanical obstruction. [Definition Source: NCI]"@en ;
            rdfs:label "Intestinal Pseudo-Obstruction"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34736
NCIT:C34736 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0022073" ;
            rdfs:comment "Inflammation of the iris and the ciliary body. [Definition Source: NCI]"@en ;
            rdfs:label "Iridocyclitis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34753
NCIT:C34753 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0022744 ;
            rdfs:comment "Trauma to the knee. [Definition Source: NCI]"@en ;
            rdfs:label "Knee Injury"@en ;
            skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C3478
NCIT:C3478 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0085580" ;
           rdfs:comment "Hypertension that presents without an identifiable cause. [Definition Source: NCI]"@en ;
           rdfs:label "Essential Hypertension"@en ;
           skos:broaderTransitive NCIT:C3117 .


###  http://purl.obolibrary.org/obo/NCIT_C34786
NCIT:C34786 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0023976" ;
            rdfs:comment "A ventricular arrhythmia characterized by a long QT interval, and accompanied by syncopal episodes sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death. [Definition Source: NCI]"@en ;
            rdfs:label "Long QT Syndrome"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34876
NCIT:C34876 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0029410 ;
            rdfs:comment "Osteoarthritis of the hip joint. [Definition Source: NCI]"@en ;
            rdfs:label "Hip Osteoarthritis"@en ;
            skos:broaderTransitive NCIT:C2883 .


###  http://purl.obolibrary.org/obo/NCIT_C34889
NCIT:C34889 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0030312" ;
            rdfs:comment "A finding of low numbers of red and white blood cells and platelets in the peripheral blood. [Definition Source: NCI]"@en ;
            rdfs:label "Pancytopenia"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C34890
NCIT:C34890 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0030319 ;
            rdfs:comment "An anxiety disorder characterized by multiple unexpected panic attacks with persistent concern of recurring attacks. Panic disorder may or may not be accompanied by agoraphobia. [Definition Source: NCI]"@en ;
            rdfs:label "Panic Disorder"@en ;
            skos:broaderTransitive NCIT:C2878 .


###  http://purl.obolibrary.org/obo/NCIT_C34911
NCIT:C34911 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0030824" ;
            rdfs:comment "An allergy to Penicillin. [Definition Source: NCI]"@en ;
            rdfs:label "Penicillin Allergy"@en ;
            skos:broaderTransitive NCIT:C112208 .


###  http://purl.obolibrary.org/obo/NCIT_C34922
NCIT:C34922 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0031212" ;
            rdfs:comment "A diverse category of psychiatric disorders characterized by behavior that deviates markedly from the expectations of the individual's culture; this pattern of deviation is pervasive and inflexible and is stable over time. The behavioral pattern negatively interferes with relationships and work. [Definition Source: NCI]"@en ;
            rdfs:label "Personality Disorder"@en ;
            skos:broaderTransitive NCIT:C2893 .


###  http://purl.obolibrary.org/obo/NCIT_C34932
NCIT:C34932 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1761609" ;
            rdfs:comment "Inflammation of the lungs due to the inhalation of solid or liquid material. [Definition Source: NCI]"@en ;
            rdfs:label "Aspiration Pneumonitis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34935
NCIT:C34935 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0032650" ;
            rdfs:comment "Swelling and protrusion of the gastrocnemius-semimembranosus bursa due to an accumulation of synovial fluid. [Definition Source: NCI]"@en ;
            rdfs:label "Baker Cyst"@en ;
            skos:broaderTransitive NCIT:C2978 .


###  http://purl.obolibrary.org/obo/NCIT_C34995
NCIT:C34995 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0036202" ;
            rdfs:comment "An idiopathic inflammatory disorder characterized by the formation of non-necrotizing epithelioid granulomas which contain giant cells. It usually affects the lungs, lymph nodes, liver, and skin. Cardiac involvement is also possible. [Definition Source: NCI]"@en ;
            rdfs:label "Sarcoidosis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C34997
NCIT:C34997 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0036205" ;
            rdfs:comment "Sarcoidosis affecting the lung parenchyma. It is characterized by the presence of non-necrotizing granulomas in the lung tissues. It is manifested with dyspnea, cough, fever, night sweats, fatigue, and weight loss. [Definition Source: NCI]"@en ;
            rdfs:label "Pulmonary Sarcoidosis"@en ;
            skos:broaderTransitive NCIT:C34995 ,
                                   NCIT:C98541 .


###  http://purl.obolibrary.org/obo/NCIT_C35020
NCIT:C35020 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0037005" ;
            rdfs:comment "A dislocation of the shoulder joint. [Definition Source: NCI]"@en ;
            rdfs:label "Shoulder Dislocation"@en ;
            skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C35024
NCIT:C35024 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0037199" ;
            rdfs:comment "An acute or chronic inflammatory process affecting the mucous membranes of any sinus cavity. [Definition Source: NCI]"@en ;
            rdfs:label "Sinusitis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C35038
NCIT:C35038 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0038160" ;
            rdfs:comment "Infection by Staphylococcus. [Definition Source: NCI]"@en ;
            rdfs:label "Staphylococcal Infection"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C35053
NCIT:C35053 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0039070" ;
            rdfs:comment "A spontaneous loss of consciousness caused by insufficient blood supply to the brain. [Definition Source: NCI]"@en ;
            rdfs:label "Syncope"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C35069
NCIT:C35069 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0039730" ;
            rdfs:comment "An inherited blood disorder characterized by a decreased synthesis of one of the polypeptide chains that form hemoglobin. Anemia results from this abnormal hemoglobin formation. [Definition Source: NCI]"@en ;
            rdfs:label "Thalassemia"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C3510
NCIT:C3510 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0151779" ;
           rdfs:comment "A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma. [Definition Source: NCI]"@en ;
           rdfs:label "Cutaneous Melanoma"@en ;
           skos:broaderTransitive NCIT:C2920 .


###  http://purl.obolibrary.org/obo/NCIT_C35131
NCIT:C35131 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042998" ;
            rdfs:comment "An inflammatory pathologic process that affects the vulva and the vagina. [Definition Source: NCI]"@en ;
            rdfs:label "Vulvovaginitis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C35204
NCIT:C35204 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0155626" ;
            rdfs:comment "Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations. [Definition Source: NCI]"@en ;
            rdfs:label "Acute Myocardial Infarction"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C35350
NCIT:C35350 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0435750" ;
            rdfs:comment "A traumatic break in one of the bones in the rib cage that does not involve a break in the adjacent skin. [Definition Source: NCI]"@en ;
            rdfs:label "Closed Fracture of Rib"@en ;
            skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C35475
NCIT:C35475 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0518988" ;
            rdfs:comment "An infectious process that affects a tooth. It is characterized by localized periapical or periodontal collection of pus. It presents with pain and swelling of the gums and/or cheek. [Definition Source: NCI]"@en ;
            rdfs:label "Tooth Abscess"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C35548
NCIT:C35548 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1136085" ;
            rdfs:comment "An abnormal laboratory test result indicating the presence of monoclonal immunoglobulins in the blood or urine. [Definition Source: NCI]"@en ;
            rdfs:label "Monoclonal Gammopathy"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C36282
NCIT:C36282 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0575141" ;
            rdfs:comment "Symptoms, physical examination results, and/or laboratory test results related to the head and neck. [Definition Source: NCI]"@en ;
            rdfs:label "Head and Neck Finding"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C3671
NCIT:C3671 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3263723" ;
           rdfs:comment "Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. [Definition Source: NCI]"@en ;
           rdfs:label "Injury"@en ;
           skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C37920
NCIT:C37920 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0428977" ;
            rdfs:comment "An abnormally slow heart rate. Thresholds for different age, gender, and patient populations exist. [Definition Source: NCI]"@en ;
            rdfs:label "Bradycardia"@en ;
            skos:broaderTransitive NCIT:C2881 .


###  http://purl.obolibrary.org/obo/NCIT_C37967
NCIT:C37967 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1522133" ;
            rdfs:comment "A laboratory test result indicating an increased amount of cholesterol in the blood. [Definition Source: NCI]"@en ;
            rdfs:label "Hypercholesterolemia"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C38012
NCIT:C38012 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0033687" ;
            rdfs:comment "The presence of abnormal amounts of protein in the urine. [Definition Source: NCI]"@en ;
            rdfs:label "Proteinuria"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C38057
NCIT:C38057 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0042571" ;
            rdfs:comment "A feeling of movement, a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). Vertigo is medically distinct from dizziness, lightheadedness, and unsteadiness. [Definition Source: NCI]"@en ;
            rdfs:label "Vertigo"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C3852
NCIT:C3852 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0236075 ;
           rdfs:comment "Any of the mental or physical manifestations that accompany perimenopause and menopause. [Definition Source: NCI]"@en ;
           rdfs:label "Menopausal Symptom"@en ;
           skos:broaderTransitive NCIT:C4876 .


###  http://purl.obolibrary.org/obo/NCIT_C3884
NCIT:C3884 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0241060" ;
           rdfs:comment "A cystic lesion located in the skin. [Definition Source: NCI]"@en ;
           rdfs:label "Skin Cyst"@en ;
           skos:broaderTransitive NCIT:C2978 .


###  http://purl.obolibrary.org/obo/NCIT_C4017
NCIT:C4017 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C1527349 ;
           rdfs:comment "A breast carcinoma arising from the ducts. While ductal carcinomas can arise at other sites, this term is universally used to refer to carcinomas of the breast. Ductal carcinomas account for about two thirds of all breast cancers. Two types of ductal carcinomas have been described: ductal carcinoma in situ (DCIS) and invasive breast carcinoma of no special type. The latter often spreads to the axillary lymph nodes and other anatomic sites. The two forms of ductal carcinoma often coexist. [Definition Source: NCI]"@en ;
           rdfs:label "Breast Ductal Carcinoma"@en ;
           skos:broaderTransitive NCIT:C4872 .


###  http://purl.obolibrary.org/obo/NCIT_C40197
NCIT:C40197 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1512433" ;
            rdfs:comment "A precancerous neoplastic process that affects the cervical squamous epithelium. It is usually associated with human papillomavirus infection. It is classified as cervical squamous intraepithelial neoplasia 2 when there is nuclear atypia in both the upper and lower epithelial layers, mitotic figures are confined to the basal two-thirds of the epithelium, and maturation is present in the upper half of the epithelium. It is classified as cervical squamous intraepithelial neoplasia 3 when there is nuclear atypia and mitotic figures throughout the entire thickness of the epithelium, and maturation is absent or confined to the upper third of the epithelium. [Definition Source: NCI]"@en ;
            rdfs:label "High Grade Cervical Squamous Intraepithelial Neoplasia"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C4345
NCIT:C4345 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1292778" ;
           rdfs:comment "A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008) [Definition Source: NCI]"@en ;
           rdfs:label "Myeloproliferative Neoplasm"@en ;
           skos:broaderTransitive NCIT:C3262 .


###  http://purl.obolibrary.org/obo/NCIT_C4349
NCIT:C4349 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0338106" ;
           rdfs:comment "An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma. [Definition Source: NCI]"@en ;
           rdfs:label "Colon Adenocarcinoma"@en ;
           skos:broaderTransitive NCIT:C2852 .


###  http://purl.obolibrary.org/obo/NCIT_C4786
NCIT:C4786 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0497327" ;
           rdfs:comment "Loss of intellectual abilities interfering with an individual's social and occupational functions. Causes include Alzheimer's disease, brain injuries, brain tumors, and vascular disorders. [Definition Source: NCI]"@en ;
           rdfs:label "Dementia"@en ;
           skos:broaderTransitive NCIT:C4802 .


###  http://purl.obolibrary.org/obo/NCIT_C4802
NCIT:C4802 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0270715" ;
           rdfs:comment "A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function. [Definition Source: NCI]"@en ;
           rdfs:label "Central Nervous System Degenerative Disorder"@en ;
           skos:broaderTransitive NCIT:C27586 .


###  http://purl.obolibrary.org/obo/NCIT_C4847
NCIT:C4847 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C1302363 ;
           rdfs:comment "A morphologic finding indicating the presence of dysplastic glandular epithelial cells in the colonic mucosa. There is no evidence of invasion. [Definition Source: NCI]"@en ;
           rdfs:label "Colon Dysplasia"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C4872
NCIT:C4872 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0678222" ;
           rdfs:comment "A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla. [Definition Source: NCI]"@en ;
           rdfs:label "Breast Carcinoma"@en ;
           skos:broaderTransitive NCIT:C2916 .


###  http://purl.obolibrary.org/obo/NCIT_C4876
NCIT:C4876 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1457887" ;
           rdfs:comment "Subjective evidence of disease perceived by the patient. [Definition Source: NCI]"@en ;
           rdfs:label "Symptom"@en ;
           skos:broaderTransitive NCIT:C100104 .


###  http://purl.obolibrary.org/obo/NCIT_C48824
NCIT:C48824 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0024094" ;
            rdfs:comment "The part of the spine in the lower back that consists of the lumbar region and the sacrum. [Definition Source: NCI]"@en ;
            rdfs:label "Lumbosacral Region"@en .


###  http://purl.obolibrary.org/obo/NCIT_C4914
NCIT:C4914 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0699893" ;
           rdfs:comment "A carcinoma that arises from the skin. Representative examples are basal cell carcinoma and squamous cell carcinoma. [Definition Source: NCI]"@en ;
           rdfs:label "Skin Carcinoma"@en ;
           skos:broaderTransitive NCIT:C2916 ,
                                  NCIT:C2920 .


###  http://purl.obolibrary.org/obo/NCIT_C49343
NCIT:C49343 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0149871" ;
            rdfs:comment "A blood clot in a deep vein, predominantly in the lower extremity, but may include the pelvis or upper extremity. [Definition Source: NCI][attribution: NICHD]"@en ;
            rdfs:label "Deep Vein Thrombosis"@en ;
            skos:broaderTransitive NCIT:C2931 .


###  http://purl.obolibrary.org/obo/NCIT_C50466
NCIT:C50466 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004238" ;
            rdfs:comment "A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC) [Definition Source: NCI]"@en ;
            rdfs:label "Atrial Fibrillation"@en ;
            skos:broaderTransitive NCIT:C2881 .


###  http://purl.obolibrary.org/obo/NCIT_C50530
NCIT:C50530 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0011880" ;
            rdfs:comment "The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids. [Definition Source: NCI]"@en ;
            rdfs:label "Diabetic Ketoacidosis"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C50577
NCIT:C50577 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0018801" ;
            rdfs:comment "Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction. [Definition Source: NCI]"@en ;
            rdfs:label "Heart Failure"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C50579
NCIT:C50579 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0018944 ;
            rdfs:comment "A localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel. [Definition Source: NCI]"@en ;
            rdfs:label "Hematoma"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C50643
NCIT:C50643 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0270697" ;
            rdfs:comment "Headache in erect position, after lumbar puncture; due to lowering of intracranial pressure by leakage of cerebrospinal fluid through the needle tract. [Definition Source: NCI]"@en ;
            rdfs:label "Lumbar Puncture Headache"@en ;
            skos:broaderTransitive NCIT:C34661 .


###  http://purl.obolibrary.org/obo/NCIT_C50667
NCIT:C50667 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1709158" ;
            rdfs:comment "An abnormality that affects hearing within the first month after birth. It may or may not result in hearing loss. [Definition Source: NCI]"@en ;
            rdfs:label "Neonatal Hearing Impairment"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C50713
NCIT:C50713 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0034065" ;
            rdfs:comment "The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung. [Definition Source: NCI]"@en ;
            rdfs:label "Pulmonary Embolism"@en ;
            skos:broaderTransitive NCIT:C2931 .


###  http://purl.obolibrary.org/obo/NCIT_C50781
NCIT:C50781 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007787" ;
            rdfs:comment "A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. [Definition Source: NCI]"@en ;
            rdfs:label "Transient Ischemic Attack"@en ;
            skos:broaderTransitive NCIT:C27586 .


###  http://purl.obolibrary.org/obo/NCIT_C51224
NCIT:C51224 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0004239" ;
            rdfs:comment "A disorder characterized by an electrocardiographic finding of an organized, regular atrial rhythm with atrial rate of 240-340 beats per minute. Multiple P waves typically appear in the inferior leads in a saw tooth-like pattern between the QRS complexes. (CDISC) [Definition Source: NCI]"@en ;
            rdfs:label "Atrial Flutter"@en ;
            skos:broaderTransitive NCIT:C2881 .


###  http://purl.obolibrary.org/obo/NCIT_C51447
NCIT:C51447 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0035229 ;
            rdfs:comment "Impairment of gas exchange within the lungs secondary to a disease process, neoplasm, or trauma, possibly resulting in hypoxia, hypercarbia, or both, but not requiring intubation or mechanical ventilation. Patients are normally managed with pharmaceutical therapy, supplemental oxygen, or both. [Definition Source: NCI]"@en ;
            rdfs:label "Pulmonary Insufficiency"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C51605
NCIT:C51605 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:SurgicalType ;
            dcterms:conformsTo UMLS:C0041271 ;
            rdfs:comment "Surgery to remove part or all of the fallopian tube(s). [Definition Source: NCI]"@en ;
            rdfs:label "Salpingectomy"@en .


###  http://purl.obolibrary.org/obo/NCIT_C51750
NCIT:C51750 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:SurgicalType ;
            dcterms:conformsTo UMLS:C0161872 ;
            rdfs:comment "Total or partial excision of the turbinates. [Definition Source: NCI]"@en ;
            rdfs:label "Turbinectomy"@en .


###  http://purl.obolibrary.org/obo/NCIT_C53458
NCIT:C53458 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0311392" ;
            rdfs:comment "Objective evidence of disease perceptible to the examining healthcare provider. [Definition Source: NCI]"@en ;
            rdfs:label "Sign"@en ;
            skos:broaderTransitive NCIT:C100104 .


###  http://purl.obolibrary.org/obo/NCIT_C54578
NCIT:C54578 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:Gene ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1420306" ;
            rdfs:comment "This gene plays a role in the detoxification of superoxide radicals in the cytosol. [Definition Source: NCI]"@en ;
            rdfs:label "SOD1 Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C55098
NCIT:C55098 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1557189" ;
            rdfs:comment "An enzyme that is normally present in liver and heart cells. SGPT is released into blood when the liver or heart is damaged. The blood SGPT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise SGPT levels. Also called alanine aminotransferase (ALT). [Definition Source: RxList] Common Terminology Criteria for Adverse Events (CTCAE) [Definition Source: U.s. Department of Health and Human Services]"@en ;
            rdfs:label "Serum Glutamic Pyruvic Transaminase, CTCAE"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C60785
NCIT:C60785 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0149889" ;
            rdfs:comment "A pathologic tract that connects an opening in the anal canal to the perianal skin. In the vast majority of cases there is a history of perianal abscess. [Definition Source: NCI]"@en ;
            rdfs:label "Anorectal Fistula"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C60989
NCIT:C60989 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0026896" ;
            rdfs:comment "A chronic autoimmune neuromuscular disorder characterized by skeletal muscle weakness. It is caused by the blockage of the acetylcholine receptors at the neuromuscular junction. [Definition Source: NCI]"@en ;
            rdfs:label "Myasthenia Gravis"@en ;
            skos:broaderTransitive NCIT:C99383 .


###  http://purl.obolibrary.org/obo/NCIT_C61277
NCIT:C61277 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0003872" ;
            rdfs:comment "Joint inflammation associated with psoriasis. [Definition Source: NCI]"@en ;
            rdfs:label "Psoriatic Arthritis"@en ;
            skos:broaderTransitive NCIT:C2883 .


###  http://purl.obolibrary.org/obo/NCIT_C61443
NCIT:C61443 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0002453" ;
            rdfs:comment "The absence of menses in a woman who has achieved reproductive age. [Definition Source: NCI]"@en ;
            rdfs:label "Amenorrhea"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C61595
NCIT:C61595 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0023791" ;
            rdfs:comment "A naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with antioxidant and potential chemopreventive activities. Alpha-lipoic acid acts as a free radical scavenger and assists in repairing oxidative damage and regenerates endogenous antioxidants, including vitamins C and E and glutathione. This agent also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids. [Definition Source: NCI]"@en ;
            rdfs:label "Alpha-Lipoic Acid"@en ;
            skos:broaderTransitive NCIT:C1505 .


###  http://purl.obolibrary.org/obo/NCIT_C6727
NCIT:C6727 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0162678" ;
           rdfs:comment "An autosomal dominant hereditary neoplastic syndrome. Two distinct clinicopathological entities are recognized: neurofibromatosis type 1 and neurofibromatosis type 2. Neurofibromatosis type 1 is associated with the presence of cafe-au-lait cutaneous lesions, multiple neurofibromas, malignant peripheral nerve sheath tumors, optic nerve gliomas, and bone lesions. Neurofibromatosis type 2 is associated with the presence of schwannomas, meningiomas, and gliomas. [Definition Source: NCI]"@en ;
           rdfs:label "Neurofibromatosis"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C69313
NCIT:C69313 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0728985" ;
            rdfs:comment "The set of vertebrae immediately caudal to the skull. [Definition Source: NCI]"@en ;
            rdfs:label "Cervical Spine"@en .


###  http://purl.obolibrary.org/obo/NCIT_C69314
NCIT:C69314 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3887615" ;
            rdfs:comment "Those vertebrae between the ribs and the pelvis, L1-L5 in man. [Definition Source: NCI]"@en ;
            rdfs:label "Lumbar Spine"@en .


###  http://purl.obolibrary.org/obo/NCIT_C69315
NCIT:C69315 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:AnatomicalSite ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0581269" ;
            rdfs:comment "The vertebrae of the thoracic spine, numbered one through twelve in man. [Definition Source: NCI]"@en ;
            rdfs:label "Thoracic Spine"@en .


###  http://purl.obolibrary.org/obo/NCIT_C70428
NCIT:C70428 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0036749" ;
            rdfs:comment "Inflammation of a serous membrane. [Definition Source: NCI]"@en ;
            rdfs:label "Serositis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C71079
NCIT:C71079 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0019360" ;
            rdfs:comment "A common dermal and neurologic disorder caused by reactivation of the varicella-zoster virus that has remained dormant within dorsal root ganglia, often for decades, after the patient's initial exposure to the virus in the form of varicella (chickenpox). It is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. [Definition Source: NCI]"@en ;
            rdfs:label "Herpes Zoster"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C71398
NCIT:C71398 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0337573" ;
            rdfs:comment "A male grandchild. [Definition Source: NCI]"@en ;
            rdfs:label "Grandson"@en ;
            skos:broaderTransitive NCIT:C19811 .


###  http://purl.obolibrary.org/obo/NCIT_C71399
NCIT:C71399 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo UMLS:C0337561 ;
            rdfs:comment "A female grandchild. [Definition Source: NCI]"@en ;
            rdfs:label "Granddaughter"@en ;
            skos:broaderTransitive NCIT:C19811 .


###  http://purl.obolibrary.org/obo/NCIT_C71408
NCIT:C71408 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0337578" ;
            rdfs:comment "A daughter of your brother or sister. [Definition Source: NCI]"@en ;
            rdfs:label "Niece"@en ;
            skos:broaderTransitive NCIT:C19811 .


###  http://purl.obolibrary.org/obo/NCIT_C71409
NCIT:C71409 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0337579" ;
            rdfs:comment "A son of your brother or sister. [Definition Source: NCI]"@en ;
            rdfs:label "Nephew"@en ;
            skos:broaderTransitive NCIT:C19811 .


###  http://purl.obolibrary.org/obo/NCIT_C71410
NCIT:C71410 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo UMLS:C0337580 ;
            rdfs:comment "A child of your aunt or uncle or their descendents. [Definition Source: NCI]"@en ;
            rdfs:label "Cousin"@en .


###  http://purl.obolibrary.org/obo/NCIT_C71411
NCIT:C71411 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0337583" ;
            rdfs:comment "A child of your aunt or uncle. [Definition Source: NCI]"@en ;
            rdfs:label "First Cousin"@en ;
            skos:broaderTransitive NCIT:C100808 .


###  http://purl.obolibrary.org/obo/NCIT_C7405
NCIT:C7405 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0017154" ;
           rdfs:comment "Atrophic gastritis that is persistent and long-standing. [Definition Source: NCI]"@en ;
           rdfs:label "Chronic Atropic Gastritis"@en ;
           skos:broaderTransitive NCIT:C26780 .


###  http://purl.obolibrary.org/obo/NCIT_C7510
NCIT:C7510 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007115" ;
           rdfs:comment "A primary or metastatic malignant neoplasm affecting the thyroid gland. [Definition Source: NCI]"@en ;
           rdfs:label "Malignant Thyroid Gland Neoplasm"@en ;
           skos:broaderTransitive NCIT:C26893 .


###  http://purl.obolibrary.org/obo/NCIT_C7570
NCIT:C7570 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0027962" ;
           rdfs:comment "A neoplasm composed of melanocytes that usually appears as a dark spot on the skin. [Definition Source: NCI]"@en ;
           rdfs:label "Melanocytic Nevus"@en ;
           skos:broaderTransitive NCIT:C3262 .


###  http://purl.obolibrary.org/obo/NCIT_C78302
NCIT:C78302 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0392171" ;
            rdfs:comment "Complaints describing a pattern similar to influenza, which may include one or more of the following symptoms: fever, chills, muscle or body aches, cough, sore throat, rhinitis, or fatigue. [Definition Source: NCI]"@en ;
            rdfs:label "Flu-Like Symptoms"@en ;
            skos:broaderTransitive NCIT:C4876 .


###  http://purl.obolibrary.org/obo/NCIT_C78576
NCIT:C78576 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0033975 ;
            rdfs:comment "A mental disorder characterized by personality change, impaired functioning, and loss of touch with reality. [Definition Source: NCI]"@en ;
            rdfs:label "Psychosis"@en ;
            skos:broaderTransitive NCIT:C2893 .


###  http://purl.obolibrary.org/obo/NCIT_C78593
NCIT:C78593 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0152169" ;
            rdfs:comment "Paroxysmal and severe flank pain radiating to the inguinal area. It is caused by the passage of a kidney stone through the ureter. [Definition Source: NCI]"@en ;
            rdfs:label "Renal Colic"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C79532
NCIT:C79532 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2607914" ;
            rdfs:comment "Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life. [Definition Source: NCI]"@en ;
            rdfs:label "Allergic Rhinitis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C79593
NCIT:C79593 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015371" ;
            rdfs:comment "A movement disorder caused by defects in the basal ganglia. The clinical manifestations include changes in the muscle tone, dyskinesia, and akinesia. Causes include vascular disorders, degenerative disorders, and antipsychotic drugs. [Definition Source: NCI]"@en ;
            rdfs:label "Extrapyramidal Disorder"@en ;
            skos:broaderTransitive NCIT:C4802 .


###  http://purl.obolibrary.org/obo/NCIT_C80020
NCIT:C80020 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:Gene ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1420588" ;
            rdfs:comment "This gene is involved in transcription and mRNA splicing. [Definition Source: NCI]"@en ;
            rdfs:label "TARDBP Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C80310
NCIT:C80310 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C2698259" ;
            rdfs:comment "A monoclonal expansion of B-lymphocytes with or without the characteristic immunophenotype of chronic lymphocytic leukemia. It precedes virtually all cases of chronic lymphocytic leukemia/small lymphocytic lymphoma. [Definition Source: NCI]"@en ;
            rdfs:label "Monoclonal B_Cell Lymphocytosis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C80385
NCIT:C80385 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0242339" ;
            rdfs:comment "A lipoprotein metabolism disorder characterized by decreased levels of high-density lipoproteins, or elevated levels of plasma cholesterol, low-density lipoproteins and/or triglycerides. [Definition Source: NCI]"@en ;
            rdfs:label "Dyslipidemia"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C8366
NCIT:C8366 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0878500 ;
           rdfs:comment "A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. According to the degree of nuclear atypia, number of mitotic figures, and presence of architectural distortion, it is classified as low grade (mild dysplasia) or high grade (moderate or severe dysplasia). [Definition Source: NCI]"@en ;
           rdfs:label "Intraepithelial Neoplasia"@en ;
           skos:broaderTransitive NCIT:C3262 .


###  http://purl.obolibrary.org/obo/NCIT_C84484
NCIT:C84484 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0162316" ;
            rdfs:comment "Anemia caused by low iron intake, inefficient iron absorption in the gastrointestinal tract, or chronic blood loss. [Definition Source: NCI]"@en ;
            rdfs:label "Iron-Deficiency Anemia"@en ;
            skos:broaderTransitive NCIT:C2869 .


###  http://purl.obolibrary.org/obo/NCIT_C84505
NCIT:C84505 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0039685 ;
            rdfs:comment "A congenital heart disorder characterized by the presence of the following four abnormalities: ventricular septal defect, pulmonary stenosis, overriding aorta, and right ventricular hypertrophy. [Definition Source: NCI]"@en ;
            rdfs:label "Tetralogy of Fallot"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C84601
NCIT:C84601 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0242644" ;
            rdfs:comment "A disorder caused by a spinal injury leading to an incomplete spinal lesion. Patients develop paralysis, ataxia and loss of sensation. Causes include spinal cord tumors, spinal traumas, ischemia, and inflammatory processes affecting the spine. [Definition Source: NCI]"@en ;
            rdfs:label "Brown-Sequard Syndrome"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C84705
NCIT:C84705 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0015523" ;
            rdfs:comment "A rare inherited bleeding disorder caused by deficiency of coagulation factor XI. It may be asymptomatic or manifest with bleeding. [Definition Source: NCI]"@en ;
            rdfs:label "Hereditary Factor XI Deficiency"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C84719
NCIT:C84719 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0338451" ;
            rdfs:comment "A syndrome caused by progressive degeneration of the frontal or temporal lobes of the brain. It is manifested with personality changes and deterioration of the language skills. [Definition Source: NCI]"@en ;
            rdfs:label "Frontotemporal Dementia"@en ;
            skos:broaderTransitive NCIT:C4786 .


###  http://purl.obolibrary.org/obo/NCIT_C84770
NCIT:C84770 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0598608 ;
            rdfs:comment "A serious metabolic condition caused by mutations in the MTHFR gene, medications, or nutritional deficiency. It results in increased levels of homocysteine in the blood. Patients with this condition are at an increased risk for recurrent blood clots formation and cardiovascular accidents. [Definition Source: NCI]"@en ;
            rdfs:label "Hyperhomocysteinemia"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C84776
NCIT:C84776 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0020757" ;
            rdfs:comment "A group of inherited or acquired skin disorders characterized by a dry, thickened, and scaly skin. The skin changes range from mild to severe. [Definition Source: NCI]" ;
            rdfs:label "Ichthyosis" ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C8486
NCIT:C8486 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0677721" ;
           rdfs:comment "Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid. [Definition Source: NCI]"@en ;
           rdfs:label "Ann Arbor Stage IV Mantle Cell Lymphoma"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C84950
NCIT:C84950 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0029134" ;
            rdfs:comment "A disorder characterized by inflammation of the optic nerve. Causes include autoimmune disorders, infections, toxins, drugs, and multiple sclerosis. It may manifest with acute loss of vision and pain. [Definition Source: NCI]"@en ;
            rdfs:label "Optic Neuritis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C85024
NCIT:C85024 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0282513" ;
            rdfs:comment "A rare neurologic progressive disorder characterized by impairment of the language and speech abilities. [Definition Source: NCI]"@en ;
            rdfs:label "Primary Progressive Aphasia"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C85026
NCIT:C85026 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0030442 ;
            rdfs:comment "A progressive motor neuron disorder affecting the muscles which are innervated by cranial nerves of the lower brain stem. Signs and symptoms include difficulties in chewing and swallowing, dysarthria, and weakness of the facial muscles and tongue. [Definition Source: NCI]"@en ;
            rdfs:label "Progressive Bulbar Palsy"@en ;
            skos:broaderTransitive <http://purl.bioontology.org/ontology/SNOMEDCT/37340000> .


###  http://purl.obolibrary.org/obo/NCIT_C85027
NCIT:C85027 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C0917981 ;
            rdfs:comment "A rare, milder form of amyotrophic lateral sclerosis. It is characterized by a slowly progressive clinical course. Signs and symptoms include muscle weakness, atrophy, and fasciculation. [Definition Source: NCI]"@en ;
            rdfs:label "Progressive Muscular Atrophy"@en ;
            skos:broaderTransitive NCIT:C34373 .


###  http://purl.obolibrary.org/obo/NCIT_C8509
NCIT:C8509 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0677930" ;
           rdfs:comment "A tumor at the original site of origin. [Definition Source: NCI]"@en ;
           rdfs:label "Primary Neoplasm"@en ;
           skos:broaderTransitive NCIT:C3262 .


###  http://purl.obolibrary.org/obo/NCIT_C85233
NCIT:C85233 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1839259" ;
            rdfs:comment "A rare, slowly progressive degenerative disorder affecting males. It is caused by mutations in the androgen receptor (AR) gene. It is characterized by bulbar and limb muscle weakness and atrophy, and gynecomastia. [Definition Source: NCI]"@en ;
            rdfs:label "Spinal and Bulbar Muscular Atrophy, X-linked 1"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C8668
NCIT:C8668 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0854831" ;
           rdfs:comment "Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid. [Definition Source: NCI]"@en ;
           rdfs:label "Ann Arbor Stage IV T-Cell Non-Hodgkin Lymphoma"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C87069
NCIT:C87069 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0008925" ;
            rdfs:comment "A congenital abnormality consisting of a fissure in the midline of the hard and/or soft palate; it is the result of the failure of the two sides of the palate to fuse during embryonic development. [Definition Source: NCI]"@en ;
            rdfs:label "Cleft Palate"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C87497
NCIT:C87497 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0016053" ;
            rdfs:comment "A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation. [Definition Source: NCI]"@en ;
            rdfs:label "Fibromyalgia"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C89715
NCIT:C89715 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0149931" ;
            rdfs:comment "A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity. [Definition Source: NCI]"@en ;
            rdfs:label "Migraine"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C9039
NCIT:C9039 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C0302592 ;
           rdfs:comment "A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are squamous cell carcinoma and adenocarcinoma. [Definition Source: NCI]"@en ;
           rdfs:label "Cervical Carcinoma"@en ;
           skos:broaderTransitive NCIT:C27020 ,
                                  NCIT:C2916 .


###  http://purl.obolibrary.org/obo/NCIT_C9175
NCIT:C9175 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0021843" ;
           rdfs:comment "Blockage of the normal flow of the intestinal contents within the bowel. [Definition Source: NCI]"@en ;
           rdfs:label "Bowel Obstruction"@en ;
           skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C91852
NCIT:C91852 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:Gene ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C1414860" ;
            rdfs:comment "This gene is involved in gene expression, genomic integrity and RNA processing. [Definition Source: NCI]"@en ;
            rdfs:label "FUS Gene"@en .


###  http://purl.obolibrary.org/obo/NCIT_C92200
NCIT:C92200 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0525045" ;
            rdfs:comment "A category of psychiatric disorders which have as their most predominant feature a disturbance in mood. [Definition Source: NCI]"@en ;
            rdfs:label "Mood Disorder"@en ;
            skos:broaderTransitive NCIT:C2893 .


###  http://purl.obolibrary.org/obo/NCIT_C9242
NCIT:C9242 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0007102" ;
           rdfs:comment "A primary or metastatic malignant neoplasm that affects the colon. Representative examples include carcinoma, lymphoma, and sarcoma. [Definition Source: NCI]"@en ;
           rdfs:label "Malignant Colon Neoplasm"@en ;
           skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C92560
NCIT:C92560 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C4317146" ;
            rdfs:comment "The backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the stomach). [Definition Source: NCI]"@en ;
            rdfs:label "Gastroesophageal Reflux"@en ;
            skos:broaderTransitive NCIT:C3367 .


###  http://purl.obolibrary.org/obo/NCIT_C93040
NCIT:C93040 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001973" ;
            rdfs:comment "Physical and psychological dependence on alcohol. [Definition Source: NCI]"@en ;
            rdfs:label "Alcohol Dependance"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C9305
NCIT:C9305 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0006826" ;
           rdfs:comment "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. [Definition Source: NCI]"@en ;
           rdfs:label "Malignant Neoplasm"@en ;
           skos:broaderTransitive NCIT:C3262 .


###  http://purl.obolibrary.org/obo/NCIT_C9384
NCIT:C9384 rdf:type owl:NamedIndividual ,
                    skos:Concept ,
                    bto:DiseaseDisorderOrFinding ;
           dcterms:conformsTo UMLS:C1378703 ;
           rdfs:comment "A carcinoma arising from the epithelium of the renal parenchyma or the renal pelvis. The majority are renal cell carcinomas. Kidney carcinomas usually affect middle aged and elderly adults. Hematuria, abdominal pain, and a palpable mass are common symptoms. [Definition Source: NCI]"@en ;
           rdfs:label "Kidney Carcinoma"@en ;
           skos:broaderTransitive NCIT:C2916 .


###  http://purl.obolibrary.org/obo/NCIT_C94575
NCIT:C94575 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0036285" ;
            rdfs:comment "A streptococcal infection, mainly occurring among children, that is characterized by a red skin rash, sore throat, and fever. [Definition Source: NCI]"@en ;
            rdfs:label "Scarlet Fever"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C94676
NCIT:C94676 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo UMLS:C2986622 ;
            rdfs:comment "A neoplastic process in the cervix characterized by morphologic features of both moderate and severe intraepithelial neoplasia. [Definition Source: NCI]"@en ;
            rdfs:label "Cervical Intraepithelial Neoplasia Grade 2/3"@en ;
            skos:broaderTransitive NCIT:C27020 .


###  http://purl.obolibrary.org/obo/NCIT_C96569
NCIT:C96569 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3272868" ;
            rdfs:comment "A female relative who is a sibling of either of the biological parents, and who share a common ancestor. [Definition Source: NCI]"@en ;
            rdfs:label "Aunt"@en ;
            skos:broaderTransitive NCIT:C19811 .


###  http://purl.obolibrary.org/obo/NCIT_C96573
NCIT:C96573 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0337477" ;
            rdfs:comment "A male relative who is the biological father of either the biological mother or the biological father. [Definition Source: NCI]"@en ;
            rdfs:label "Grandfather"@en ;
            skos:broaderTransitive NCIT:C19811 .


###  http://purl.obolibrary.org/obo/NCIT_C96574
NCIT:C96574 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0337476" ;
            rdfs:comment "A female relative who is the biological mother of either the biological mother or the biological father. [Definition Source: NCI]"@en ;
            rdfs:label "Grandmother"@en ;
            skos:broaderTransitive NCIT:C19811 .


###  http://purl.obolibrary.org/obo/NCIT_C96575
NCIT:C96575 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3272872" ;
            rdfs:comment "A female relative who is a sibling of the biological mother, and who both share a common ancestor. [Definition Source: NCI]"@en ;
            rdfs:label "Maternal Aunt"@en ;
            skos:broaderTransitive NCIT:C96569 .


###  http://purl.obolibrary.org/obo/NCIT_C96579
NCIT:C96579 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo UMLS:C3272876 ;
            rdfs:comment "A male relative who is a sibling of the biological mother, and who both share a common ancestor. [Definition Source: NCI]"@en ;
            rdfs:label "Maternal Uncle"@en ;
            skos:broaderTransitive NCIT:C96587 .


###  http://purl.obolibrary.org/obo/NCIT_C96581
NCIT:C96581 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C3272877" ;
            rdfs:comment "A female relative who is a sibling of the biological father, and who both share a common ancestor. [Definition Source: NCI]"@en ;
            rdfs:label "Paternal Aunt"@en ;
            skos:broaderTransitive NCIT:C96569 .


###  http://purl.obolibrary.org/obo/NCIT_C96585
NCIT:C96585 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo UMLS:C3272881 ;
            rdfs:comment "A male relative who is a sibling of the biological father, and who both share a common ancestor. [Definition Source: NCI]"@en ;
            rdfs:label "Paternal Uncle"@en ;
            skos:broaderTransitive NCIT:C96587 .


###  http://purl.obolibrary.org/obo/NCIT_C96587
NCIT:C96587 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:KinshipType ;
            dcterms:conformsTo UMLS:C3272882 ;
            rdfs:comment "A male relative who is a sibling of either of the biological parents, and who share a common ancestor. [Definition Source: NCI]"@en ;
            rdfs:label "Uncle"@en ;
            skos:broaderTransitive NCIT:C19811 .


###  http://purl.obolibrary.org/obo/NCIT_C97132
NCIT:C97132 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0008049" ;
            rdfs:comment "A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rash, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. [Definition Source: NCI]"@en ;
            rdfs:label "Chicken Pox"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C97142
NCIT:C97142 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0001361" ;
            rdfs:comment "An acute inflammation of the tonsils caused by viruses or bacteria. Signs and symptoms include fever, enlargement of the tonsils, difficulty swallowing, and enlargement of the regional lymph nodes. [Definition Source: NCI]"@en ;
            rdfs:label "Acute Tonsillitis"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C98541
NCIT:C98541 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0746102" ;
            rdfs:comment "A persistent non-neoplastic disorder of the lungs. Representative examples include: chronic obstructive pulmonary disease, chronic bronchitis, emphysema, pulmonary fibrosis, pneumoconiosis, asbestosis, atelectasis, radiation induced pneumonitis, and radiation fibrosis. [Definition Source: NCI]"@en ;
            rdfs:label "Chronic Lung Disorder"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C98967
NCIT:C98967 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0022738" ;
            rdfs:comment "A rare congenital syndrome characterized by the fusion of the vertebrae in the cervical spine. Patients present with a short neck and restricted mobility of the upper spine. Other signs and symptoms include scoliosis, spina bifida, cleft palate, and rib malformations. [Definition Source: NCI]"@en ;
            rdfs:label "Klippel-Feil Syndrome"@en ;
            skos:broaderTransitive NCIT:C2991 .


###  http://purl.obolibrary.org/obo/NCIT_C99039
NCIT:C99039 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0034628" ;
            rdfs:comment "Traumatic or pathological injury to the radius bone in which the continuity of the bone is broken. [Definition Source: NCI]"@en ;
            rdfs:label "Radius Fracture"@en ;
            skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C99083
NCIT:C99083 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0040185" ;
            rdfs:comment "Traumatic or pathological injury to the tibia in which the continuity of the bone is broken. [Definition Source: NCI]"@en ;
            rdfs:label "Tibia Fracture"@en ;
            skos:broaderTransitive NCIT:C3671 .


###  http://purl.obolibrary.org/obo/NCIT_C99383
NCIT:C99383 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:DiseaseDisorderOrFinding ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0751871" ;
            rdfs:comment "A disorder characterized by the degeneration of the nervous system due to autoimmunity. Representative examples include multiple sclerosis, Guillain-Barre syndrome, and myasthenia gravis. [Definition Source: NCI]"@en ;
            rdfs:label "Autoimmune Nervous System Disorder"@en ;
            skos:broaderTransitive NCIT:C2889 .


###  http://purl.obolibrary.org/obo/OAE_0000005
<http://purl.obolibrary.org/obo/OAE_0000005> rdf:type owl:NamedIndividual ,
                                                      skos:Concept ,
                                                      bto:AdverseDrugReaction ;
                                             rdfs:comment "An adverse event that occurs after a drug administration. [Definition Source: OAE]"@en ;
                                             rdfs:label "Adverse Drug Event"@en .


###  http://purl.obolibrary.org/obo/OAE_0000220
<http://purl.obolibrary.org/obo/OAE_0000220> rdf:type owl:NamedIndividual ,
                                                      skos:Concept ,
                                                      bto:AdverseDrugReaction ;
                                             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0852908" ;
                                             rdfs:comment "An errored drug administration where a patient is administered with an ineffective drug. [Definition Source: OAE]"@en ;
                                             rdfs:label "Administration of Ineffective Drug"@en ;
                                             skos:broaderTransitive <http://purl.obolibrary.org/obo/OAE_0000005> .


###  http://purl.obolibrary.org/obo/OAE_0000890
<http://purl.obolibrary.org/obo/OAE_0000890> rdf:type owl:NamedIndividual ,
                                                      skos:Concept ,
                                                      bto:AdverseDrugReaction ;
                                             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0013182" ;
                                             rdfs:comment "A hypersensitivity AE that has an outcome of allergic reactions to certain drugs. [Definition Source: OAE]"@en ;
                                             rdfs:label "Drug Hypersensitivity AE"@en ;
                                             skos:broaderTransitive <http://purl.obolibrary.org/obo/OAE_0000005> .


###  http://purl.obolibrary.org/obo/OAE_0000891
<http://purl.obolibrary.org/obo/OAE_0000891> rdf:type owl:NamedIndividual ,
                                                      skos:Concept ,
                                                      bto:AdverseDrugReaction ;
                                             dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C0277585" ;
                                             rdfs:comment "A drug AE that has an outcome of lower threshold to the normal pharmacologic action of a drug. [Definition Source: OAE]"@en ;
                                             rdfs:label "Drug Intolerance AE"@en ;
                                             skos:broaderTransitive <http://purl.obolibrary.org/obo/OAE_0000005> .


###  https://imm.medicina.ulisboa.pt/
<https://imm.medicina.ulisboa.pt/> rdf:type owl:NamedIndividual ,
                                            bto:ClinicsAndHospitals ;
                                   rdfs:label "Institute of Molecular Medicine Joao Lobo Antunes"@en ,
                                              "Instituto de medicina molecular Joao Lobo Antunes"@pt .


###  https://orcid.org/0000-0001-9219-6239
<https://orcid.org/0000-0001-9219-6239> rdf:type owl:NamedIndividual ,
                                                 <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
                                        rdfs:label "Nicola Ferro"@en ;
                                        foaf:name "Nicola Ferro"@en .


###  https://orcid.org/0000-0001-9709-6392
<https://orcid.org/0000-0001-9709-6392> rdf:type owl:NamedIndividual ,
                                                 <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
                                        rdfs:label "Giorgio Maria Di Nunzio"@en ;
                                        foaf:name "Giorgio Maria Di Nunzio"@en .


###  https://orcid.org/0000-0002-0676-682X
<https://orcid.org/0000-0002-0676-682X> rdf:type owl:NamedIndividual ,
                                                 <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
                                        rdfs:label "Laura Menotti"@en ;
                                        foaf:name "Laura Menotti"@en .


###  https://orcid.org/0000-0002-5070-2049
<https://orcid.org/0000-0002-5070-2049> rdf:type owl:NamedIndividual ,
                                                 <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
                                        rdfs:label "Guglielmo Faggioli"@en ;
                                        foaf:name "Guglielmo Faggioli" .


###  https://orcid.org/0000-0003-0362-5893
<https://orcid.org/0000-0003-0362-5893> rdf:type owl:NamedIndividual ,
                                                 <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
                                        rdfs:label "Stefano Marchesin"@en ;
                                        foaf:name "Stefano Marchesin"@en .


###  https://orcid.org/0000-0003-4970-4554
<https://orcid.org/0000-0003-4970-4554> rdf:type owl:NamedIndividual ,
                                                 <http://www.w3.org/2000/10/swap/pim/contact#Person> ;
                                        rdfs:label "Gianmaria Silvello"@en ;
                                        foaf:name "Gianmaria Silvello"@en .


###  https://w3id.org/brainteaser/ontology/schema/BehavioralImpairment
bto:BehavioralImpairment rdf:type owl:NamedIndividual ,
                                  skos:Concept ,
                                  bto:DiseaseDisorderOrFinding ;
                         rdfs:comment "Diminished psychological function."@en ;
                         rdfs:label "Behavioral Impairment"@en ;
                         skos:broaderTransitive NCIT:C3367 .


###  https://w3id.org/brainteaser/ontology/schema/CortisoneTherapyForRelapse
bto:CortisoneTherapyForRelapse rdf:type owl:NamedIndividual ,
                                        skos:Concept ,
                                        bto:TherapeuticProcedureType ;
                               rdfs:comment "Therapy based on cortisone used for treating relapses."@en ;
                               rdfs:label "Cortisone Therapy for Relapse"@en .


###  https://w3id.org/brainteaser/ontology/schema/DrugsForMSSymptomaticTherapy
bto:DrugsForMSSymptomaticTherapy rdf:type owl:NamedIndividual ,
                                          skos:Concept ,
                                          bto:TherapeuticProcedureType ;
                                 rdfs:comment "Symptomatic therapy for Multiple Sclerosis (MS)."@en ;
                                 rdfs:label "Drugs for MS Symptomatic Therapy"@en .


###  https://w3id.org/brainteaser/ontology/schema/DrugsForMSTherapySideEffects
bto:DrugsForMSTherapySideEffects rdf:type owl:NamedIndividual ,
                                          skos:Concept ,
                                          bto:TherapeuticProcedureType ;
                                 rdfs:comment "Therapy for managing side effects of MS therapy."@en ;
                                 rdfs:label "Drugs for MS Therapy Side Effects"@en .


###  https://w3id.org/brainteaser/ontology/schema/DrugsForOtherDiseases
bto:DrugsForOtherDiseases rdf:type owl:NamedIndividual ,
                                   skos:Concept ,
                                   bto:TherapeuticProcedureType ;
                          rdfs:comment "Any drugs used to treat other diseases."@en ;
                          rdfs:label "Drugs for Other Diseases"@en .


###  https://w3id.org/brainteaser/ontology/schema/ImmunoactiveDrugs
bto:ImmunoactiveDrugs rdf:type owl:NamedIndividual ,
                               skos:Concept ,
                               bto:TherapeuticProcedureType ;
                      rdfs:comment "Therapy employed to slow the progression of the disease."@en ;
                      rdfs:label "Immunoactive Drugs"@en .


###  https://w3id.org/brainteaser/ontology/schema/J07BX03
bto:J07BX03 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo "https://uts.nlm.nih.gov/uts/umls/concept/C5400806" ;
            rdfs:label "Covid-19 Vaccines"@en ;
            skos:broaderTransitive ATC:J07BX .


###  https://w3id.org/brainteaser/ontology/schema/N07XX09
bto:N07XX09 rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            dcterms:conformsTo ATC:L04AX07 ;
            rdfs:label "BG-12"@en ;
            skos:broaderTransitive ATC:N07 .


###  https://w3id.org/brainteaser/ontology/schema/ecunerv
bto:ecunerv rdf:type owl:NamedIndividual ,
                     skos:Concept ,
                     bto:PharmacologicSubstance ;
            rdfs:comment "Ecunerv is recommended to help maintain normal functions of the nervous system under abnormal conditions such as neuropathy (due to mechanical, metabolic, toxic, ischemic, optical, alcoholic, diabetic or post-herpetic causes), canalicular syndrome, radiculopathy. B-vitamins (B1, B6 and B12) work in synergy with magnesium and help maintain normal functions of the nervous system. Vitamin E helps protect cells from oxidative stress. [Definition Source: https://www.ecupharma.it/en/ecunerv - visited on November 28th, 2022]"@en ;
            rdfs:label "Ecunerv"@en ;
            skos:broaderTransitive NCIT:C1505 ;
            skos:note "Dietary supplements do not have an ATC but they belong to the GMP class 4AA2F30."@en .


###  https://www.comunidad.madrid/hospital/gregoriomaranon/
<https://www.comunidad.madrid/hospital/gregoriomaranon/> rdf:type owl:NamedIndividual ,
                                                                  bto:ClinicsAndHospitals ;
                                                         rdfs:label "Hospital General Universitario Gregorio Marañón"@en .


###  https://www.mondino.it/
<https://www.mondino.it/> rdf:type owl:NamedIndividual ,
                                   bto:ClinicsAndHospitals ;
                          rdfs:label "Mondino Foundation"@en .


###  https://www.unipd.it/
<https://www.unipd.it/> rdf:type owl:NamedIndividual ,
                                 bto:ClinicsAndHospitals ;
                        rdfs:label "University of Padua"@en ,
                                   "Università degli Studi di Padova"@it .


###  https://www.unito.it/
<https://www.unito.it/> rdf:type owl:NamedIndividual ,
                                 bto:ClinicsAndHospitals ;
                        rdfs:label "University of Turin"@en ,
                                   "Università degli Studi di Torino"@it .


#################################################################
#    Annotations
#################################################################

<http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#NO2_concentration> rdfs:label "Nitrogen Dioxide concentration"@en .


<http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#O3_concentration> rdfs:label "Ozone concentration"@en .


<http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#PM10_concentration> rdfs:label "Particulate Matter <10 µm concentration"@en .


<http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#PM2.5_concentration> rdfs:label "Particulate Matter <2.5 µm concentration"@en .


<http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#SO2_concentration> rdfs:label "Sulphur Dioxide concentration"@en .


###  Generated by the OWL API (version 4.5.9.2019-02-01T07:24:44Z) https://github.com/owlcs/owlapi